BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0116.p (447 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb21486 [GEPR] COG0477 Permeases of the major facilitator super... 513 e-145 CC1774 [GEPR] COG0477 Permeases of the major facilitator superfa... 479 e-135 AGc231 [GEPR] COG0477 Permeases of the major facilitator superfa... 440 e-123 mll6844 [GEPR] COG0477 Permeases of the major facilitator superf... 438 e-122 SMc01869 [GEPR] COG0477 Permeases of the major facilitator super... 269 1e-71 >SMb21486 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 431 Score = 513 bits (1320), Expect = e-145, Method: Compositional matrix adjust. Identities = 253/423 (59%), Positives = 327/423 (77%), Gaps = 1/423 (0%) Query: 26 HDHGKIEPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEP-KLEGTLYAFVIFA 84 HD + G IA+GVVIGRA+E+FDFFVY +ASV+VFP +FFP P +L TLY+F IF+ Sbjct: 9 HDDTPVSAGNIAIGVVIGRAAEFFDFFVYGIASVVVFPQLFFPFAPDRLTATLYSFAIFS 68 Query: 85 FAFLARPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLL 144 AF+ARP+G+ +FMAI + YGR VKLT+ALF+LG STA IA LP + +G W+I+LL++ Sbjct: 69 LAFVARPVGSLVFMAIDRTYGRGVKLTIALFLLGGSTASIAFLPGYATLGAWSIVLLAVF 128 Query: 145 RVGQGLALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTA 204 R+GQG ALGGAWDGL SLLA+NAPQH RGWYA + QLGAPLGF++A++LFAY L S++ A Sbjct: 129 RLGQGFALGGAWDGLASLLALNAPQHHRGWYAMIPQLGAPLGFMLASALFAYFLVSISKA 188 Query: 205 DFLEWGWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNII 264 DFL WGWRYPF+VAFAINVVALF+RLRLV E+ LLD EL+ A V E+ G N++ Sbjct: 189 DFLAWGWRYPFFVAFAINVVALFTRLRLVMTKEFGTLLDLHELQAAPVTEVLRANGGNVL 248 Query: 265 IGALAALASYALFHLVTVFPLSWIKLYSLREATDFLVVQIWGGLIMAVGIVISGLIADRF 324 +GA LAS+ALFHLVTVFPLSW+++Y+ A+ FL+VQ G + + I+ SGLIADR Sbjct: 249 VGAFVPLASFALFHLVTVFPLSWVEIYTDHGASSFLMVQFLGAVCGILAIIASGLIADRI 308 Query: 325 GRRNTLGSMALLIAILSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKAR 384 GRRN LG A+LIAI S P L+ G G++ F+++GF +LGLS+GQAAGAV + F Sbjct: 309 GRRNHLGICAVLIAIFSFVAPMLLQAGATGRDVFVIVGFTILGLSFGQAAGAVASRFGKA 368 Query: 385 YRYTGAALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALSLNRALEA 444 YRYTGAALTSDL+WL+GAGFAPLVALGL++ FG+A+ +YLLSGA+ ++ AL ++ LE Sbjct: 369 YRYTGAALTSDLSWLIGAGFAPLVALGLTSRFGLAFAGYYLLSGALCTILALVFSKKLEI 428 Query: 445 RDD 447 ++ Sbjct: 429 DNE 431 >CC1774 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 446 Score = 479 bits (1232), Expect = e-135, Method: Compositional matrix adjust. Identities = 241/421 (57%), Positives = 318/421 (75%), Gaps = 1/421 (0%) Query: 27 DHGKIEPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLYAFVIFAFA 86 D + PGEIA+GVVIGR SE+FDFFVYA+ASVLVFP + FP +L G + AF +FA A Sbjct: 23 DDKGVRPGEIALGVVIGRTSEFFDFFVYAIASVLVFPQLVFPFVDRLTGVMLAFGLFALA 82 Query: 87 FLARPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLLRV 146 F+ARP G+ IF AI + YGR VKLT+ALF+LG STA I++LP+F +G AI L+ R+ Sbjct: 83 FIARPFGSVIFGAIDQRYGRGVKLTIALFLLGGSTAVISMLPSFAAVGPIAIWALAACRI 142 Query: 147 GQGLALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTADF 206 GQGLAL GAWDG+ SLLA+NAP++KRGWYA + QLGAP GF++A+ LFAY +++L ADF Sbjct: 143 GQGLALAGAWDGMASLLALNAPENKRGWYAMIPQLGAPFGFMLASGLFAYFVATLAPADF 202 Query: 207 LEWGWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNIIIG 266 L+WGWRYPF+ AFAINVVALF+RLR+V+ E+ L ++REL P V L +G N++IG Sbjct: 203 LDWGWRYPFFAAFAINVVALFARLRIVATEEFGALFEKRELRPTRVASLLRAEGGNVLIG 262 Query: 267 ALAALASYALFHLVTVFPLSWIKLY-SLREATDFLVVQIWGGLIMAVGIVISGLIADRFG 325 A A LA++A+FHLVTVFPLSW+ L+ ++A +FL ++++G L+ GI+ SG IADR Sbjct: 263 AFAPLATFAMFHLVTVFPLSWVVLHGDAQQALNFLRIELFGALVGVGGILASGWIADRIT 322 Query: 326 RRNTLGSMALLIAILSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKARY 385 R+N L ALLI S P L++GG GQ +++IGFA+LGLS+GQAAGAV++ F RY Sbjct: 323 RQNQLALSALLIGAFSLLAPRLLDGGATGQTAYVVIGFAILGLSFGQAAGAVSSGFSKRY 382 Query: 386 RYTGAALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALSLNRALEAR 445 RYTGAALTSDL+WL+GAGFAPL ALGL++ +G+ + YL SGA+ +L AL+++R R Sbjct: 383 RYTGAALTSDLSWLIGAGFAPLAALGLASLWGLPAIGLYLASGALATLLALTIDRTRRRR 442 Query: 446 D 446 Sbjct: 443 Q 443 >AGc231 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 440 Score = 440 bits (1132), Expect = e-123, Method: Compositional matrix adjust. Identities = 216/418 (51%), Positives = 296/418 (70%) Query: 30 KIEPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLYAFVIFAFAFLA 89 ++P I + V++ R +E+FDFF+YA+AS LVFP VFF L TLY+F +F+ AF+A Sbjct: 23 SVDPDRITIAVILARMTEFFDFFIYAIASALVFPHVFFSFVDPLTATLYSFAVFSLAFIA 82 Query: 90 RPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLLRVGQG 149 RPIG+ IF+ I + +GR VKL ALF L ST I+ LP+++ G+ A LL+ R+GQG Sbjct: 83 RPIGSLIFLQIDRKFGRAVKLMAALFTLCGSTMAISFLPSYDEAGMLAPCLLAAFRIGQG 142 Query: 150 LALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTADFLEW 209 L LGGAWDGL SLLAMNAPQ +RGWYA + Q+GA +GF +A++ F ++ L+ A+FL W Sbjct: 143 LGLGGAWDGLVSLLAMNAPQKQRGWYAMMPQIGAAMGFGLASAFFIVFVTQLSNAEFLAW 202 Query: 210 GWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNIIIGALA 269 GWR+PF+VA A+NV+ALF+RLR++ PE+ +L++ ELEP + + +Q ++ GA Sbjct: 203 GWRFPFFVALALNVLALFARLRMIVTPEFQAMLEQHELEPRPMFRMLRSQFPVVLTGAFV 262 Query: 270 ALASYALFHLVTVFPLSWIKLYSLREATDFLVVQIWGGLIMAVGIVISGLIADRFGRRNT 329 LAS+ALFHLVTVFPLSW+ L + + +DFL VQ +I IV+SG++ADR GRR Sbjct: 263 PLASFALFHLVTVFPLSWVSLNTSQRVSDFLFVQFVSAIICGGMIVVSGILADRIGRRKL 322 Query: 330 LGSMALLIAILSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKARYRYTG 389 L A LI + S P L++ G+ G+ F+LIGF+LLGLS+GQA GA+ + F YRYTG Sbjct: 323 LAIAAALIGLFSLVAPVLLSSGDIGRYLFVLIGFSLLGLSFGQAGGALASRFSREYRYTG 382 Query: 390 AALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALSLNRALEARDD 447 A+LTSD++WL+GAGFAPLVALG S+ FG+ V YL+SGAV +L AL +R LE + Sbjct: 383 ASLTSDISWLIGAGFAPLVALGFSSKFGLFAVGIYLMSGAVCTLVALWFSRTLEMPSE 440 >mll6844 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 411 Score = 438 bits (1126), Expect = e-122, Method: Compositional matrix adjust. Identities = 225/407 (55%), Positives = 300/407 (73%) Query: 40 VVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLYAFVIFAFAFLARPIGTTIFMA 99 +++GR SE+FDFFVYA+ASV+VFP + FP L GTLY+F IFA AF+ARP G+ +FMA Sbjct: 1 MIVGRTSEFFDFFVYAIASVIVFPKLVFPTHDPLVGTLYSFCIFALAFVARPFGSVLFMA 60 Query: 100 IQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLLRVGQGLALGGAWDGL 159 I + YGR KLT+ALF+LG ST IA LP + IG A+ LL+L R+GQGLALGG WDGL Sbjct: 61 IDRAYGRGAKLTIALFLLGTSTVAIAFLPAYGDIGAVAVWLLALARIGQGLALGGTWDGL 120 Query: 160 PSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTADFLEWGWRYPFYVAF 219 PSLLA+NAPQ++RG+YA + QLGAP+G +VA+SLFA+ +++L+ DF WGWRYPF+VAF Sbjct: 121 PSLLALNAPQNRRGFYAMIPQLGAPIGLIVASSLFAFFVANLSADDFFSWGWRYPFFVAF 180 Query: 220 AINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNIIIGALAALASYALFHL 279 AINVVALF+RLR+V PE++KL + +L+P + + +G N++IGA A LAS+ALFH+ Sbjct: 181 AINVVALFARLRIVVTPEFSKLYESGDLQPTRIRDTIRAEGHNVVIGAFAPLASFALFHM 240 Query: 280 VTVFPLSWIKLYSLREATDFLVVQIWGGLIMAVGIVISGLIADRFGRRNTLGSMALLIAI 339 VTVFPLSW+ L++ FL+++ L IV SG +ADR GRR LG A+ IA Sbjct: 241 VTVFPLSWVFLFTNEGPARFLMIEAVSALFGIAAIVASGPLADRVGRRALLGGSAIAIAT 300 Query: 340 LSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKARYRYTGAALTSDLAWL 399 S F P L++GG G+ F+++GF LLGLS+GQ++G V ++F +YRYTG+A+TSDLAW+ Sbjct: 301 FSGFAPQLLDGGAVGEALFMVLGFILLGLSFGQSSGVVASSFSRQYRYTGSAITSDLAWM 360 Query: 400 VGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALSLNRALEARD 446 GAGFAPL AL L+ +FG+ YLLSGA +L AL ++ A D Sbjct: 361 FGAGFAPLAALLLAGNFGLIAAGAYLLSGAACTLLALWIDGRRPAAD 407 >SMc01869 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 436 Score = 269 bits (687), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 164/420 (39%), Positives = 240/420 (57%), Gaps = 4/420 (0%) Query: 26 HDHGKIEPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLYAFVIFAF 85 H P + ++G E+FDF+VYA A+V++FP +FFP L + F+ Sbjct: 16 HRQAVNSPARVLFASLVGTTIEFFDFYVYATAAVIIFPHLFFPAADPTSAMLQSLATFSI 75 Query: 86 AFLARPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLLR 145 AF ARP+G IF GR+ L AL +G ST I LLPT+ IGV A +LL+L R Sbjct: 76 AFFARPLGAVIFGHFGDRIGRKATLVAALMTMGISTVVIGLLPTYSTIGVVAPLLLALCR 135 Query: 146 VGQGLALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTAD 205 GQGL LGG W G L NAP+ KR WYA QLGAP+GF+++A F + ++ Sbjct: 136 FGQGLGLGGEWGGAVLLATENAPEGKRSWYAMFPQLGAPIGFILSAGTFLILGEVMSEEA 195 Query: 206 FLEWGWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNIII 265 FL WGWR PF + + +V L+ RL++ PE+ K +D+ E V + + R++++ Sbjct: 196 FLAWGWRVPFIASVLLVIVGLYVRLKITETPEFQKAIDKHERVEVPVAAIFRSHKRSLVL 255 Query: 266 GALAALASYALFHLVTVFPLSW--IKLYSLREATDFLVVQIWGGLIMAVGIVISGLIADR 323 G ALA++ LF+L+TVF LSW KL RE FL+VQ+ G + + I +SG+++DR Sbjct: 256 GTFVALATFVLFYLMTVFSLSWGTTKLGYSRE--QFLLVQMTGVVFFGLMIPVSGILSDR 313 Query: 324 FGRRNTLGSMALLIAILSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKA 383 FGRR L + I + F+ L++ G G F ++G L+GL+YG A+ A F Sbjct: 314 FGRRLVLVLTTIGIGVFGLFMAPLLSSGLGGAFVFSIVGLGLMGLTYGPIGAALAAPFPT 373 Query: 384 RYRYTGAALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALSLNRALE 443 RYTGA++T +LA + GA AP +A L+ ++ + +V +YLL+ A +L L L+ E Sbjct: 374 AVRYTGASMTFNLAGIFGASLAPYIATWLATNYSLGHVGYYLLAAASITLVCLLLSNEEE 433