BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0101.p (243 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value XF2477 [H] COG0132 Dethiobiotin synthetase Xfa Xylella fastidios... 172 6e-43 STM0797 [H] COG0132 Dethiobiotin synthetase Sty Salmonella typhi... 169 4e-42 ZbioD [H] COG0132 Dethiobiotin synthetase EcZ Escherichia coli O... 169 5e-42 ECs0856 [H] COG0132 Dethiobiotin synthetase Ecs Escherichia coli... 169 5e-42 VC1115 [H] COG0132 Dethiobiotin synthetase Vch Vibrio cholerae 168 1e-41 >XF2477 [H] COG0132 Dethiobiotin synthetase Xfa Xylella fastidiosa 9a5c Length = 226 Score = 172 bits (436), Expect = 6e-43, Method: Compositional matrix adjust. Identities = 107/218 (49%), Positives = 135/218 (61%), Gaps = 1/218 (0%) Query: 17 KGIFVTGTDTGVGKTLVASALVHLHAAHGLRCVGMKPVASGAFHDGQRWCNEDVLALQAQ 76 +VTGTDTG+GKT V+ L+H+ G R VGMKPVASG + W NED LALQA Sbjct: 4 SAFYVTGTDTGIGKTFVSCILLHMLRGRGQRAVGMKPVASGCTYSDTGWRNEDALALQAA 63 Query: 77 ANVQVPPQWVNPYLLRRATAPHIAAAEEGVTIELEHLAACHAHLAAASDCVIVEGAGGFM 136 ++ +NPY L A AP IAA E GVT+ LE L+A L A +D V+VEG GG+ Sbjct: 64 SDPTPAYDLINPYALPAAVAPEIAAIEAGVTVALEPLSAAFTQLRAQADVVVVEGVGGWA 123 Query: 137 VPLDARHNTDDLVARLGLPVVLVVGMRLGCINHALLTQQAIAARGLPLLGWVANEIDPAE 196 PL+A + LV L +PVVLVVG+RLGC+NHA L+ AI A GL +GW+AN IDP Sbjct: 124 TPLNATIDQATLVRALEIPVVLVVGLRLGCLNHARLSTTAIMADGLRCIGWIANTIDPHM 183 Query: 197 ACMDAMVESLQARLHAPLLGRLP-WQPGMSAQEAAARL 233 A ++ + L+ RL P G LP PG++ AARL Sbjct: 184 ARIEENLALLRQRLPIPYWGHLPHIPPGINPATLAARL 221 >STM0797 [H] COG0132 Dethiobiotin synthetase Sty Salmonella typhimurium LT2 Length = 228 Score = 169 bits (429), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 99/216 (45%), Positives = 131/216 (60%), Gaps = 5/216 (2%) Query: 17 KGIFVTGTDTGVGKTLVASALVHLHAAHGLRCVGMKPVASGA--FHDGQRWCNEDVLALQ 74 K FVTGTDT VGKT+ + AL+ G + VG KPVASG+ DG R N D LALQ Sbjct: 3 KRYFVTGTDTEVGKTVASCALLQAATQLGYQTVGYKPVASGSEMTTDGLR--NSDALALQ 60 Query: 75 AQANVQVPPQWVNPYLLRRATAPHIAAAEEGVTIELEHLAACHAHLAAASDCVIVEGAGG 134 +++ P +NPY T+PHI +A+EG I+ L+ L A +D V+ EGAGG Sbjct: 61 RNSSLPQPYSAINPYTFAEPTSPHIVSADEGRAIDAAVLSRGLRTLEAQADWVLTEGAGG 120 Query: 135 FMVPLDARHNTDDLVARLGLPVVLVVGMRLGCINHALLTQQAIAARGLPLLGWVANEIDP 194 + PL A D V LPV+LVVG++LGCINHA+LT A+ GLPL+GW+AN+I P Sbjct: 121 WFTPLSATLTFADWVQTEQLPVILVVGVKLGCINHAMLTALAVEQAGLPLVGWIANDIQP 180 Query: 195 AEACMDAMVESLQARLHAPLLGRLPWQPGMSAQEAA 230 A + +L+ + APLLG +PW G+S +AA Sbjct: 181 PGARHGEYLATLRRVIPAPLLGEIPWL-GVSPSQAA 215 >ZbioD [H] COG0132 Dethiobiotin synthetase EcZ Escherichia coli O157:H7 EDL933 Length = 225 Score = 169 bits (428), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 93/204 (45%), Positives = 122/204 (59%) Query: 17 KGIFVTGTDTGVGKTLVASALVHLHAAHGLRCVGMKPVASGAFHDGQRWCNEDVLALQAQ 76 K FVTGTDT VGKT+ + AL+ A G R G KPVASG+ + N D LALQ Sbjct: 3 KRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEGLRNSDALALQRN 62 Query: 77 ANVQVPPQWVNPYLLRRATAPHIAAAEEGVTIELEHLAACHAHLAAASDCVIVEGAGGFM 136 +++Q+ VNPY T+PHI +A+EG +IE +++ L +D V+VEGAGG+ Sbjct: 63 SSLQLDYATVNPYTFAEPTSPHIISAQEGRSIESSVMSSGLRALEQQADWVLVEGAGGWF 122 Query: 137 VPLDARHNTDDLVARLGLPVVLVVGMRLGCINHALLTQQAIAARGLPLLGWVANEIDPAE 196 PL D V + LPV+LVVG++LGCINHA+LT QAI GL L GWVAN++ P Sbjct: 123 TPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQAIQHAGLTLAGWVANDVTPPG 182 Query: 197 ACMDAMVESLQARLHAPLLGRLPW 220 + +L + APLLG PW Sbjct: 183 KRHAEYMTTLTRMIPAPLLGESPW 206 >ECs0856 [H] COG0132 Dethiobiotin synthetase Ecs Escherichia coli O157:H7 Length = 225 Score = 169 bits (428), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 93/204 (45%), Positives = 122/204 (59%) Query: 17 KGIFVTGTDTGVGKTLVASALVHLHAAHGLRCVGMKPVASGAFHDGQRWCNEDVLALQAQ 76 K FVTGTDT VGKT+ + AL+ A G R G KPVASG+ + N D LALQ Sbjct: 3 KRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEGLRNSDALALQRN 62 Query: 77 ANVQVPPQWVNPYLLRRATAPHIAAAEEGVTIELEHLAACHAHLAAASDCVIVEGAGGFM 136 +++Q+ VNPY T+PHI +A+EG +IE +++ L +D V+VEGAGG+ Sbjct: 63 SSLQLDYATVNPYTFAEPTSPHIISAQEGRSIESSVMSSGLRALEQQADWVLVEGAGGWF 122 Query: 137 VPLDARHNTDDLVARLGLPVVLVVGMRLGCINHALLTQQAIAARGLPLLGWVANEIDPAE 196 PL D V + LPV+LVVG++LGCINHA+LT QAI GL L GWVAN++ P Sbjct: 123 TPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQAIQHAGLTLAGWVANDVTPPG 182 Query: 197 ACMDAMVESLQARLHAPLLGRLPW 220 + +L + APLLG PW Sbjct: 183 KRHAEYMTTLTRMIPAPLLGESPW 206 >VC1115 [H] COG0132 Dethiobiotin synthetase Vch Vibrio cholerae Length = 238 Score = 168 bits (425), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 90/217 (41%), Positives = 126/217 (58%) Query: 12 YRARHKGIFVTGTDTGVGKTLVASALVHLHAAHGLRCVGMKPVASGAFHDGQRWCNEDVL 71 Y IF+ GTDT VGKT+ + A++ A H + +G KPVA+G+ + N D L Sbjct: 5 YSPMRNAIFIAGTDTDVGKTVASKAILQALATHNIATIGYKPVAAGSDKTEFGYRNSDAL 64 Query: 72 ALQAQANVQVPPQWVNPYLLRRATAPHIAAAEEGVTIELEHLAACHAHLAAASDCVIVEG 131 L A V +P + VNPY L T+PHIAA E VTI+ L+ + ++ V+VEG Sbjct: 65 HLMKAATVDMPYEDVNPYALVLPTSPHIAAKHENVTIDYALLSNKLSKHKQNAELVVVEG 124 Query: 132 AGGFMVPLDARHNTDDLVARLGLPVVLVVGMRLGCINHALLTQQAIAARGLPLLGWVANE 191 AGG+ VP V + LPV+LVVG++LGC++HA+LT +AI A GL L+GW+AN Sbjct: 125 AGGWRVPTSDSDCLSTWVKQERLPVILVVGIKLGCLSHAILTAEAIRADGLELVGWIANR 184 Query: 192 IDPAEACMDAMVESLQARLHAPLLGRLPWQPGMSAQE 228 I+P ++E L+ RL P LG +P+ P QE Sbjct: 185 INPGTEHYAEIIEHLEGRLGTPKLGEIPYMPKAKRQE 221