BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0018.0091.p         (135 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AGl595 [IQR] COG1028 Dehydrogenases with different specificities...   122   3e-28
L77482 [IQR] COG1028 Dehydrogenases with different specificities...    93   2e-19
PA1379 [IQR] COG1028 Dehydrogenases with different specificities...    89   3e-18
SMa0326 [IQR] COG1028 Dehydrogenases with different specificitie...    84   7e-17
CAC3335 [IQR] COG1028 Dehydrogenases with different specificitie...    83   1e-16

>AGl595 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Atu Agrobacterium
           tumefaciens strain C58 (Cereon)
          Length = 249

 Score =  122 bits (305), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 70/120 (58%), Positives = 83/120 (69%), Gaps = 1/120 (0%)

Query: 2   KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPRHDLLPA-SPHLRILPLDVADAHSIQ 60
            TI ITG SSG+G  IA  FL R W VIATMR P        +  LR+LPLDV +  SI 
Sbjct: 3   NTILITGTSSGYGKAIAELFLARGWNVIATMRRPSAARFAGDNGRLRVLPLDVTEEASIA 62

Query: 61  AAVEAAGPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQMRGNGRG 120
           AA+EAAGP+DVLVNNAGIG +GA EA PM+ +R +F+TN+ G +AMTQA IPQMR    G
Sbjct: 63  AAIEAAGPIDVLVNNAGIGMVGAFEATPMSAIRTIFDTNSFGVMAMTQAVIPQMRKRQSG 122


>L77482 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Lla Lactococcus
           lactis
          Length = 277

 Score = 92.8 bits (229), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 52/124 (41%), Positives = 70/124 (56%), Gaps = 7/124 (5%)

Query: 2   KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPRHDLLPA-SPHLRILPLDVADAHSIQ 60
           K + ITG S+G G E A  F +R WKV A  R  R + +P    +++ L LDV  + S Q
Sbjct: 4   KIVAITGASNGMGFEAAELFAKRGWKVYAGAR--RVEKIPQYENNIKALKLDVTSSESNQ 61

Query: 61  AAV----EAAGPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQMRG 116
           A V    + AG +DVL+NNAG G  G  E  PM ++R  FETN  G++ +TQ  +P MR 
Sbjct: 62  AFVKKILDEAGHIDVLINNAGYGEYGPAEEIPMDKIRNQFETNFFGAVELTQLVLPTMRA 121

Query: 117 NGRG 120
              G
Sbjct: 122 QNYG 125


>PA1379 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Pae Pseudomonas
           aeruginosa
          Length = 277

 Score = 88.6 bits (218), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 54/128 (42%), Positives = 73/128 (57%), Gaps = 11/128 (8%)

Query: 2   KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPR-----HDLLPASPHLRILPLDVADA 56
           KT+ ITG SSGFG  +AR  L    +V+ T+R+         + P     R+L  DV D 
Sbjct: 5   KTLLITGASSGFGQALAREALDAGHRVVGTVRSEEARSALEAVAPGQAFGRLL--DVTDL 62

Query: 57  HSIQAAVEAA----GPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIP 112
            +I+  V A     GP+DVLVN+AG G+ G LE  P+A++R  FE N  G++AM QA +P
Sbjct: 63  AAIEPTVAAIERDIGPLDVLVNSAGYGHEGILEESPLAEMRRQFEVNLFGAVAMIQAVLP 122

Query: 113 QMRGNGRG 120
            MR   RG
Sbjct: 123 YMRRRRRG 130


>SMa0326 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Sme Sinorhizobium
           meliloti
          Length = 279

 Score = 84.0 bits (206), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 51/125 (40%), Positives = 65/125 (52%), Gaps = 7/125 (5%)

Query: 2   KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPRH--DLLPASPHLRILPLDVADAHSI 59
           K   +TGCS+GFG  IA + L+   KV+ T R      DL      L ILPLDV D    
Sbjct: 7   KVWLVTGCSTGFGRYIAEHLLEVGEKVVVTARKADKIADLEQKGDAL-ILPLDVIDRDQC 65

Query: 60  QAAVEAA----GPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQMR 115
           Q  V+AA    G +DVL+NNAGIG  GA+E    +  R LF+ N  G+     + +P MR
Sbjct: 66  QKVVDAAEAHFGRIDVLINNAGIGFFGAIEETDESNARRLFDVNFFGTANTIHSVLPHMR 125

Query: 116 GNGRG 120
               G
Sbjct: 126 ARRSG 130


>CAC3335 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Cac Clostridium
           acetobutylicum
          Length = 266

 Score = 83.2 bits (204), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 48/123 (39%), Positives = 66/123 (53%), Gaps = 10/123 (8%)

Query: 4   IFITGCSSGFGLEIARYFLQRDWKVIATMRTPRHDL--LPASPHLRILPLDVADAHSIQA 61
           + ITGCS+G G E+ +    + + V+AT R    DL  LPA+  L   PLDV    S+  
Sbjct: 7   VLITGCSTGIGRELCKILYNKGYTVVATARKV-EDLKDLPAALKL---PLDVTKEESVHK 62

Query: 62  AVEAA----GPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQMRGN 117
           A++        +D+LVNNAG    GALE   ++ V+ +F  N  G I M QA IP+MR  
Sbjct: 63  AIKEVMLNFHKIDILVNNAGYSVRGALEEVNVSDVKSMFNVNVFGIINMLQAVIPEMRKR 122

Query: 118 GRG 120
             G
Sbjct: 123 KTG 125