BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0085.p (414 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc4834 [GEPR] COG0477 Permeases of the major facilitator superf... 131 3e-30 VC1634 [GEPR] COG0477 Permeases of the major facilitator superfa... 123 1e-27 Cgl2686 [GEPR] COG0477 Permeases of the major facilitator superf... 118 2e-26 SMc03825 [GEPR] COG0477 Permeases of the major facilitator super... 117 5e-26 SA2222 [GEPR] COG0477 Permeases of the major facilitator superfa... 116 1e-25 >AGc4834 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 398 Score = 131 bits (329), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 116/365 (31%), Positives = 176/365 (48%), Gaps = 32/365 (8%) Query: 6 PPSPQHPPNHPRFLLFLICAFASAGQLAIDLYVPALPEMAIDYATSAQAIQSSVTGYLIA 65 PP P L L+ A A +++ +Y PA+PE+ +AT+ AI+ S++ Y Sbjct: 2 PPEPIMSTKRTAILGALLTALA---PISMAIYTPAMPELTRVFATNESAIKLSLSLYFAG 58 Query: 66 YAFGQLVFGPLADAYGRKRILALGLGLFSLGCVLSLAAPNLETFVAARVLQGFGIAATNL 125 +A QL+ GP +DA+GR+R + L +F G +L++ AP +E + AR++QG G + Sbjct: 59 FALAQLLAGPASDAFGRRRASLVFLSVFLGGGLLAIFAPTIEVLLLARLIQGIGASVGMT 118 Query: 126 LAKAIITDSFAGQALVHAYTYMAIAWGLAPIIAPVIGAHLQEAFGWRSCLVFLLVYSLG- 184 +A+AI+ D F G + I + P + P IG AFGW+S VF L+ LG Sbjct: 119 VARAIVRDQFTGAEASSIMNLIGIMLAVGPALGPTIGGLSLAAFGWKS--VFFLMAGLGA 176 Query: 185 --MWAVLWRYRETLAQPVRL-HPATLARNARMVLASPVFQSCFLAQGLCYSILLVFNIVG 241 +++V+ RET L P L +L P F L G L + Sbjct: 177 AAIFSVVIFLRETTVPDKSLIRPRRLLSAYGNLLTEPRFLLAALVLGGSIGALYAQATML 236 Query: 242 PFMVQNTLHQPPTFFGYLALAIGMM-----YFLGGISNRITHRRLPTAEQRLRLGARVMT 296 F++ NT+ PT FG IGM+ YF G I+ R RL ++R VM Sbjct: 237 TFILINTVGMTPTAFG-----IGMLMQTGAYFFGSIALRYIAPRL--GDRR-----SVML 284 Query: 297 GAAFV---MLLLALSVGL---TVWTLCAPVLVMAFCAGAMYPTLMAKGNSIFPHIAGLTS 350 G F LL+ LSV L + +++ PV V + P+++ + FPHIAG S Sbjct: 285 GLCFSGTGGLLILLSVFLIPPSFFSIMGPVAVATVGIALLTPSMVTAALAPFPHIAGSAS 344 Query: 351 AILGF 355 A++GF Sbjct: 345 AMMGF 349 >VC1634 [GEPR] COG0477 Permeases of the major facilitator superfamily Vch Vibrio cholerae Length = 401 Score = 123 bits (308), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 102/353 (28%), Positives = 171/353 (48%), Gaps = 11/353 (3%) Query: 8 SPQHPPNHPRFLLFLICAFASAGQLAIDLYVPALPEMAIDYATSAQAIQSSVTGYLIAYA 67 + Q P L ++ A + LAID+Y+PA+P +A D+ +A A+Q ++T Y +A Sbjct: 7 NTQQTPQMSLLLYIVLGALGALTPLAIDMYLPAMPTIARDFGVNAGAVQITLTAYTAGFA 66 Query: 68 FGQLVFGPLADAYGRKRILALGLGLFSLGCVLSLAAPNLETFVAARVLQGFGIAATNLLA 127 GQL+ GPLAD++GR+ ++ G+ LF + ++S +E R QGF AA ++ Sbjct: 67 IGQLLHGPLADSFGRRPVMLCGIFLFGIAAMVSATTNGIEALTYIRAAQGFAGAAAAVVI 126 Query: 128 KAIITDSFAGQALVHAYTYMAIAWGLAPIIAPVIGAHLQEAFGWRSCL-VFLLVYSLGMW 186 +A++ D F + A +++ + LAP++AP+IG HL FGWRS V L +L + Sbjct: 127 QAVVRDMFDREDFARAMSFVTLVVTLAPLVAPMIGGHLAIWFGWRSIFWVLALFAALVIA 186 Query: 187 AVLWRYRETLA----QPVRLHPATLARNARMVLASPVFQSCFLAQGLCYSILLVFNIVGP 242 V+W+ ETL+ QP+R + RN + +PV + ++ + F G Sbjct: 187 MVMWKIPETLSPENRQPLRFR--STMRNYFDLCKNPVAMGLIFSGAFSFAGMFAFLTAGA 244 Query: 243 FMVQNTLHQPPTFFGYL-ALAIGMMYFLGGISNRITHRRLPTAEQRLRLGARVMTGAAFV 301 F+ + P FGYL L I M L I+ R + R L ++M G + Sbjct: 245 FVYIDIYGVSPDGFGYLFGLNIVAMIALTTINGRFVKKIGSHNMLRFALFLQLMAG---I 301 Query: 302 MLLLALSVGLTVWTLCAPVLVMAFCAGAMYPTLMAKGNSIFPHIAGLTSAILG 354 L ++ + +W V++ + M S +P +AG S++ G Sbjct: 302 GLFVSWVLDWGLWGTVPFVVLFVGTISTIGSNSMGLLLSKYPRMAGTASSLAG 354 >Cgl2686 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 398 Score = 118 bits (296), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 106/352 (30%), Positives = 168/352 (47%), Gaps = 17/352 (4%) Query: 35 DLYVPALPEMAIDYATSAQAIQSSVTGYLIAYAFGQLVFGPLADAYGRKRILALGLGLFS 94 D+Y+PA+P +A D T+A +Q +++ ++ A GQL+ GPL+D GRK +L G Sbjct: 27 DMYLPAMPGIAEDLGTTAPMVQLTLSSFMAGMAIGQLIIGPLSDQLGRKGLLVAGAVAAL 86 Query: 95 LGCVLSLAAPNLETFVAARVLQGFGIAATNLLAKAIITDSFAGQALVHAYTYMAIAWGLA 154 + V+ AP++ V AR++QG G A ++A+AI+ D GQ HA+ + I G+A Sbjct: 87 VASVVCALAPSISVLVIARLVQGLGGGACVVIARAIVPDLERGQKAAHAFALLMIIQGIA 146 Query: 155 PIIAPVIGAHLQEAFGWRSCLVFL-LVYSLGMWAVLWRYRETLAQPVRLHPAT----LAR 209 P++AP+IG L FGWR L LV + L + +E+ +PV A + Sbjct: 147 PVVAPLIGGVLVGPFGWRGIFWALALVNFAQLLVALLQIKES--KPVEERTAAGLGGMLS 204 Query: 210 NARMVLASPVFQSCFLAQGLCYSILLVFNIVGPFMVQNTLHQPPTFFGYLALAIGMMYFL 269 N VL +P F + GL + + + PF++QN + P + ++ G+ F Sbjct: 205 NYVFVLKNPQFLAYVFTLGLSFGAMFSYISASPFVLQNQMGIPVLLY---SIIFGVNAF- 260 Query: 270 GGISNRITHRRLPTAEQRLRLGARVMTGAAFVMLLLALSVGLTVWTLCAPVLVMAFCAGA 329 G I + +RRL R+ V+ + LL + V W +L+ + Sbjct: 261 GLIVGGMVNRRLLQRIHPHRIMQTVLASFTVLCALLLIEVLFINWIPLFLLLLFLIV--S 318 Query: 330 MYPTLMAK----GNSIFPHIAGLTSAILGFALLLVSAAMMGLAGFVSIHSLT 377 P +MA G + AG SAILGF + A + L G S +LT Sbjct: 319 HIPMVMANATALGTEVVRSRAGSGSAILGFVQFTMGALVSSLVGLGSDKALT 370 >SMc03825 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 412 Score = 117 bits (293), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 95/345 (27%), Positives = 169/345 (48%), Gaps = 20/345 (5%) Query: 22 LICAFASA-GQLAIDLYVPALPEMAIDYATSAQAIQSSVTGYLIAYAFGQLVFGPLADAY 80 +I AF A G +++ LY PA+PE+ +A+S AI+ +++ Y +AF QLV G L+D Sbjct: 12 IIGAFLVALGPISMALYTPAMPELVRAFASSEAAIKMTLSLYFGGFAFAQLVSGTLSDVI 71 Query: 81 GRKRILALGLGLFSLGCVLSLAAPNLETFVAARVLQGFGIAATNLLAKAIITDSFAGQAL 140 GR+R + + ++ G +++ AP++ +A R++QG G + +A+AI+ D F G Sbjct: 72 GRRRTTLIFMAIYLAGSLMAAFAPSIPVLLAGRLVQGIGASVGMTVARAIVRDQFTGTTA 131 Query: 141 VHAYTYMAIAWGLAPIIAPVIGAHLQEAFGWRSCLVFLLVYSLGMWAVLWRYRETLAQPV 200 + + L P ++P +G+ FGW+S + ++ ++L ++ + P Sbjct: 132 ARIMNMIGMMLALGPAVSPTLGSIALGLFGWQSIFLLMVGFALMACFIVQLFMAETTTPD 191 Query: 201 R----LHP-----ATLARNARMVLASPVFQSCFLAQGLCYSILLVFNIVGPFMVQNTLHQ 251 R P L R+ R V ++ V A G Y+ + + PF++ + + Sbjct: 192 RSKGHFRPILAAYGELMRDGRFVSSTLVIAG---AVGALYA----WATMLPFVLISQVGL 244 Query: 252 PPTFFGYLALAIGMMYFLGGISNRITHRRLPTAEQRLRLGARVMTGAAFVMLLLAL-SVG 310 PT FG L ++F G ++ R+ RR Q L GAA + L + ++ Sbjct: 245 TPTEFGIGMLMQSGLFFSGTVTMRLMMRRF--TPQALVPAGLFFIGAASLALAFTMHALE 302 Query: 311 LTVWTLCAPVLVMAFCAGAMYPTLMAKGNSIFPHIAGLTSAILGF 355 T ++ P+ + AF + P +M + FPHIAG SA++GF Sbjct: 303 PTFLSVMTPIGIYAFGIAFVMPYMMTAAMAPFPHIAGTASAMMGF 347 >SA2222 [GEPR] COG0477 Permeases of the major facilitator superfamily Sau Staphylococcus aureus N315 Length = 403 Score = 116 bits (290), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 78/254 (30%), Positives = 125/254 (49%), Gaps = 7/254 (2%) Query: 8 SPQHPPNHPRFLLFLICAFASA-GQLAIDLYVPALPEMAIDYATSAQAIQSSVTGYLIAY 66 S + H FLL + +A G L ID+YVP+LP++ D+ ++ IQ +++ +I Sbjct: 3 STKTKTKHFSFLLLITLGVMTAFGPLTIDMYVPSLPKVQGDFGSTTSEIQLTLSFTMIGL 62 Query: 67 AFGQLVFGPLADAYGRKRILALGLGLFSLGCVLSLAAPNLETFVAARVLQGFGIAATNLL 126 A GQ +FGPL+DA+GRKRI L +F L LS+ L F+ R +QG ++ Sbjct: 63 ALGQFIFGPLSDAFGRKRIAVSILIIFILVSGLSMFVDQLPLFLTLRFIQGLTGGGVIVI 122 Query: 127 AKAIITDSFAGQALVHAYTYMAIAWGLAPIIAPVIGAHLQEAFGWRSCLVFLLVYSL--- 183 AKA D F+G AL + + G+ I+AP+ G WRS L + +L Sbjct: 123 AKASAGDKFSGNALAKFLASLMVVNGIITILAPLAGGLALSVATWRSIFTILTIVALIIL 182 Query: 184 -GMWAVLWRYRETLAQPVRLHPATLARNARMVLASPVFQSCFLAQGLCYSILLVFNIVGP 242 G+ + L + + + V +++ ++ +L P F L QGL Y +L ++ P Sbjct: 183 IGVASQLPKTSKDELKQVNF--SSVIKDFGSLLKKPAFIIPMLLQGLTYVMLFSYSSASP 240 Query: 243 FMVQNTLHQPPTFF 256 F+ Q + P F Sbjct: 241 FITQKLYNMTPQQF 254