BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0029.p (484 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RP109 [C] COG0280 Phosphotransacetylase Rpr Rickettsia prowazekii 307 4e-83 CAC3076 [C] COG0280 Phosphotransacetylase Cac Clostridium acetob... 239 1e-62 TM1130 [C] COG0280 Phosphotransacetylase Tma Thermotoga maritima 208 2e-53 BS_yqiS [C] COG0280 Phosphotransacetylase Bsu Bacillus subtilis 194 5e-49 RC0147 [C] COG0280 Phosphotransacetylase Rco Rickettsia conorii 174 6e-43 >RP109 [C] COG0280 Phosphotransacetylase Rpr Rickettsia prowazekii Length = 351 Score = 307 bits (786), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 163/322 (50%), Positives = 222/322 (68%), Gaps = 13/322 (4%) Query: 170 TSLPEVSMKMGDAD------LQLLLEHARKPGPAPV--AVVHPCDELSLAAVLDAHAAGL 221 T +P +K D D + LLL R G P+ AVVHP D+ SL + A + Sbjct: 23 TYIPPTEIKDSDFDKAAKHFINLLL---RADGLKPIKTAVVHPIDKESLLGAVRAAQFNV 79 Query: 222 ISPILVAPRSRLLALAESHKLDISAFPLEDVPHSHAAAARAIELVMHGKVEMLMKGSLHT 281 I PIL+ P+ ++ ++A+ + +D+ + + + HSH AA +A+EL +V +MKG+LHT Sbjct: 80 IKPILIGPQHKIESVAKVNDVDLENYQVINAEHSHEAAKKAVELAKKREVAAIMKGALHT 139 Query: 282 EEFMGAVVACP-GLHTKRRMSHCYLMQTPAYPRPFIITDAAVNIEPGLAEKADIIRNAIE 340 +E M AVV GL T+RR+SH +LM +P+PFIITDAA+NI P L +K DI++NAI+ Sbjct: 140 DELMSAVVYKENGLRTERRISHAFLMAVATFPKPFIITDAAINIRPTLEDKRDIVQNAID 199 Query: 341 LAHVIGV-KTPKVAILAAVETVNPRMPATLDAAALCKMADRGQITGAILDGPLAFDNAVS 399 L H+I K +VA+L+AVETV +P TLDAAAL KMADRGQIT A++DGPLAFDNA+S Sbjct: 200 LMHIIKEDKQVRVAVLSAVETVTSAIPTTLDAAALSKMADRGQITNAVVDGPLAFDNAIS 259 Query: 400 PVSARVKGISSEVAGQADILVVPDLESGNLLAKQLEYMGGAISAGLVLGARIPLILTSRA 459 +A KGISS V+G ADILVVPDLESGN+LAKQL+Y+G A+ AG+VLGAR+P+ILTSRA Sbjct: 260 LFAAEAKGISSPVSGNADILVVPDLESGNMLAKQLKYLGQAVMAGIVLGARVPIILTSRA 319 Query: 460 DSRETRLASCAVARMLAQHYRS 481 D + R+ SC +A + ++ Sbjct: 320 DPIDMRVISCVLASFIYNQTKA 341 >CAC3076 [C] COG0280 Phosphotransacetylase Cac Clostridium acetobutylicum Length = 301 Score = 239 bits (610), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 126/307 (41%), Positives = 194/307 (63%), Gaps = 13/307 (4%) Query: 171 SLPEVSMKMGDADLQLLLEHARKPGPAPVAVVHPCDELSLAAVLDAHAAGLISPILVAPR 230 S E+ MK+ +++ VAV DE L AV DA G+ ILV Sbjct: 4 SFNEIIMKVKSKEMK------------KVAVAVAQDEPVLEAVRDAKKNGIADAILVGDH 51 Query: 231 SRLLALAESHKLDISAFPLEDVPHSHAAAARAIELVMHGKVEMLMKGSLHTEEFMGAVVA 290 ++++A +D++ F + + P+ AA +A+ELV GK +M+MKG ++T F+ +V+ Sbjct: 52 DEIVSIALKIGMDVNDFEIVNEPNVKKAALKAVELVSTGKADMVMKGLVNTATFLRSVLN 111 Query: 291 CP-GLHTKRRMSHCYLMQTPAYPRPFIITDAAVNIEPGLAEKADIIRNAIELAHVIGVKT 349 GL T + MSH + +T + R +TD A N P L EK DI+ N++++AH IG++ Sbjct: 112 KEVGLRTGKTMSHVAVFETEKFDRLLFLTDVAFNTYPELKEKIDIVNNSVKVAHAIGIEN 171 Query: 350 PKVAILAAVETVNPRMPATLDAAALCKMADRGQITGAILDGPLAFDNAVSPVSARVKGIS 409 PKVA + AVE +NP+MP+TLDAA L KM+DRGQI G ++DGPLA D A+S +A KG++ Sbjct: 172 PKVAPICAVEVINPKMPSTLDAAMLSKMSDRGQIKGCVVDGPLALDIALSEEAAHHKGVT 231 Query: 410 SEVAGQADILVVPDLESGNLLAKQLEYMGGAISAGLVLGARIPLILTSRADSRETRLASC 469 EVAG+ADI ++P++E+GN++ K L Y + + G+++G P++LTSRADS ET++ S Sbjct: 232 GEVAGKADIFLMPNIETGNVMYKTLTYTTDSKNGGILVGTSAPVVLTSRADSHETKMNSI 291 Query: 470 AVARMLA 476 A+A ++A Sbjct: 292 ALAALVA 298 >TM1130 [C] COG0280 Phosphotransacetylase Tma Thermotoga maritima Length = 294 Score = 208 bits (529), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 119/294 (40%), Positives = 178/294 (60%), Gaps = 3/294 (1%) Query: 184 LQLLLEHARKPGPAPVAVVHPCDELSLAAVLDAHAAGLISPILVAPRSRLLALAESHKLD 243 L+ L+E AR G +AV D+ + AV A + P+L P + + E + Sbjct: 3 LEKLVEMARGKGKK-LAVAAANDDHVIEAVYRAWRERVCEPVLFGPEEEITRIIEELVPE 61 Query: 244 ISAFPLEDVPHSHAAAARAIELVMHGKVEMLMKGSLHTEEFMGAVV-ACPGLHTKRRMSH 302 + D P A A+E V G+ + LMKG + T + M + GL T + M+ Sbjct: 62 WKNPQIIDCPPEEAGRL-AVEAVSKGECDFLMKGKIKTGDLMKIYLDERYGLRTGKTMAM 120 Query: 303 CYLMQTPAYPRPFIITDAAVNIEPGLAEKADIIRNAIELAHVIGVKTPKVAILAAVETVN 362 +M+ P +PRP II+D + I P L +K D+I + + +A+V+G++TPKVA++ A+E VN Sbjct: 121 VSVMEIPDFPRPLIISDPGMLISPTLEQKVDMIEHCVRVANVMGLETPKVAVVGAIEVVN 180 Query: 363 PRMPATLDAAALCKMADRGQITGAILDGPLAFDNAVSPVSARVKGISSEVAGQADILVVP 422 P+MP T++AA L KM RGQI G I+DGP A DN VS +A+ KGI S VAG+ADIL++P Sbjct: 181 PKMPITMEAAILSKMNQRGQIKGCIVDGPFALDNVVSEEAAKKKGIQSPVAGKADILILP 240 Query: 423 DLESGNLLAKQLEYMGGAISAGLVLGARIPLILTSRADSRETRLASCAVARMLA 476 D+E+ N+L K L ++ A SA +LG ++P++LTSRADS ET+ S A++ + A Sbjct: 241 DIEAANILYKALVFLAKAKSASTILGGKVPVVLTSRADSEETKFYSIALSAVFA 294 >BS_yqiS [C] COG0280 Phosphotransacetylase Bsu Bacillus subtilis Length = 299 Score = 194 bits (492), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 113/257 (43%), Positives = 157/257 (61%), Gaps = 8/257 (3%) Query: 231 SRLLALAESHKLD--ISAFPLEDVPHSHA-----AAARAIELVMHGKVEMLMKGSLHTEE 283 +R L +S KL+ S+ V HA +A A+ V H ++LMKG++ T Sbjct: 41 ARFLLTGDSKKLNELTSSMQGHQVEIVHANTPEESAKLAVRAVHHKTADVLMKGNVPTSV 100 Query: 284 FMGAVVA-CPGLHTKRRMSHCYLMQTPAYPRPFIITDAAVNIEPGLAEKADIIRNAIELA 342 + AV+ GL + +SH + P + R +TD+A+NI P L E I++NA+ +A Sbjct: 101 LLKAVLNRQEGLRSASVLSHVAVFDIPDFDRLMFVTDSAMNIAPSLEELRQILQNAVHVA 160 Query: 343 HVIGVKTPKVAILAAVETVNPRMPATLDAAALCKMADRGQITGAILDGPLAFDNAVSPVS 402 H +G PK A LAAVETVNP+M AT++AAAL +M RGQI G I+DGPLA DNAVS ++ Sbjct: 161 HAVGNNMPKAAALAAVETVNPKMEATVNAAALAQMYKRGQIKGCIVDGPLALDNAVSQIA 220 Query: 403 ARVKGISSEVAGQADILVVPDLESGNLLAKQLEYMGGAISAGLVLGARIPLILTSRADSR 462 A K IS +VAG DIL+VP +E+GN+L K L Y A A ++ GA+ P+ LTSRADS Sbjct: 221 AAQKKISGDVAGNPDILLVPTIEAGNILYKSLIYFAKASVAAVITGAKAPIALTSRADSA 280 Query: 463 ETRLASCAVARMLAQHY 479 E +L S A+A ++ Y Sbjct: 281 ENKLYSIALAICASEEY 297 >RC0147 [C] COG0280 Phosphotransacetylase Rco Rickettsia conorii Length = 155 Score = 174 bits (440), Expect = 6e-43, Method: Compositional matrix adjust. Identities = 87/139 (62%), Positives = 108/139 (77%), Gaps = 1/139 (0%) Query: 306 MQTPAYPRPFIITDAAVNIEPGLAEKADIIRNAIELAHVIGVKTP-KVAILAAVETVNPR 364 M +P+PFIITDAA+NI P L +K DI++NAI+L H+I T +VA+L+ VETV Sbjct: 1 MVVATFPKPFIITDAAINIRPTLEDKRDIVQNAIDLMHMIREDTQVRVAVLSVVETVTSA 60 Query: 365 MPATLDAAALCKMADRGQITGAILDGPLAFDNAVSPVSARVKGISSEVAGQADILVVPDL 424 +P TLDAAAL +M DRGQIT AI+DGPLAFDNA+S +A K ISS V+G ADILVVPDL Sbjct: 61 IPTTLDAAALSQMVDRGQITNAIVDGPLAFDNAISLFAAEAKCISSSVSGNADILVVPDL 120 Query: 425 ESGNLLAKQLEYMGGAISA 443 ESGN+LAKQL+Y+G A+ A Sbjct: 121 ESGNMLAKQLKYLGQAVMA 139