BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0050.p (291 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0136 [M] COG1560 Lauroyl/myristoyl acyltransferase Rso Ralsto... 249 4e-66 NMB1418 [M] COG1560 Lauroyl/myristoyl acyltransferase Nme Neisse... 238 9e-63 NMA1630 [M] COG1560 Lauroyl/myristoyl acyltransferase NmA Neisse... 231 1e-60 PA3242 [M] COG1560 Lauroyl/myristoyl acyltransferase Pae Pseudom... 189 5e-48 ddg [M] COG1560 Lauroyl/myristoyl acyltransferase Eco Escherichi... 156 5e-38 >RSc0136 [M] COG1560 Lauroyl/myristoyl acyltransferase Rso Ralstonia solanacearum Length = 297 Score = 249 bits (637), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 128/289 (44%), Positives = 173/289 (59%), Gaps = 5/289 (1%) Query: 2 LAIMWLLHWLPLPILGRLGEGIGSLLYLYMRPRRHIALTNLRLCFPEKTEEERVSIAREH 61 L +WLL + P + R GEG+G LLY RR + L NL+ CFPEK++ ER +IA E Sbjct: 10 LGFLWLLSFFPYGFVARFGEGLGGLLYRIPNGRRRVVLANLKACFPEKSDAEREAIAHEV 69 Query: 62 FRLFARSALERGILWWAPISRLRRLIQVEPGMPLDTFAKGPTILLAPHFVCLEIPGATLG 121 FR RS ER W+A RL+R+++++ L P IL+ H +EI L Sbjct: 70 FRKVFRSFAERSFAWFASEQRLKRVVKIDDQANLPALHGSPHILVTLHLSGVEIGALALT 129 Query: 122 VFSE----YSACTIYTKQRNDVIDRALLKGRLRFRPATLLAREQGVKPIIRAMRKGLPFL 177 + + C++YT+ N +D A+ R RF AT+++R + ++ I+R +++G Sbjct: 130 DYLREHVGNAGCSLYTRMANPALDAAIKALRSRF-GATMVSRNENIRQIMRTIKRGEALQ 188 Query: 178 MLPDMDFGIRDAEFVPFFGVPAATLTATARIAAATGAAVVPVVCTFLPGYKGWKATYYPA 237 ++ DMDFG RDAEFVPFFGV A TL A R+AA TGA VVP+ LP Y+G+ PA Sbjct: 189 LISDMDFGERDAEFVPFFGVQALTLNAIPRMAALTGARVVPMYTEILPDYQGYVLRILPA 248 Query: 238 WTDYPGEDIVAATRRMNAFIEDRVREHPAEYFWAHKRFKTRPPGEPDVY 286 W DYP D+ A TRRMNAF ED +R EY+W HKRFK RPPGEP +Y Sbjct: 249 WDDYPTGDLSADTRRMNAFFEDAIRPRITEYYWVHKRFKHRPPGEPGIY 297 >NMB1418 [M] COG1560 Lauroyl/myristoyl acyltransferase Nme Neisseria meningitidis MC58 Length = 289 Score = 238 bits (608), Expect = 9e-63, Method: Compositional matrix adjust. Identities = 119/286 (41%), Positives = 172/286 (60%), Gaps = 6/286 (2%) Query: 4 IMWLLHWLPLPILGRLGEGIGSLLYLYMRPRRHIALTNLRLCFPEKTEEERVSIAREHFR 63 ++++L +LP +L ++ + G L YL ++PRR I NL CF E +EE+R ++ ++HF+ Sbjct: 7 VLYVLQFLPFALLHKIADLTGLLAYLLVKPRRRIGEINLAKCFSEWSEEKRKTVLKQHFK 66 Query: 64 LFARSALERGILWWAPISRLRRLIQVEPGMPLD-TFAKG-PTILLAPHFVCLEIPGATLG 121 A+ LE G+ W+AP RL+ L++ LD A G I+L PHF E+ A Sbjct: 67 HMAKLMLEYGLYWYAPAGRLKSLVRYRNKHYLDDALAAGEKVIILYPHFTAFEM--AVYA 124 Query: 122 VFSEYSACTIYTKQRNDVIDRALLKGRLRFRPATLLAREQGVKPIIRAMRKG-LPFLMLP 180 + + ++Y+ Q+N ++D +LKGR R+ L+ R +G++ +++ RK PFL LP Sbjct: 125 LNQDIPLISMYSHQKNKILDEQILKGRNRYHNVFLIGRTEGLRALVKQFRKSSAPFLYLP 184 Query: 181 DMDFGIRDAEFVPFFGVPAATLTATARIAAATGAAVVPVVCTFLPGYKGWKATYYPAWTD 240 D DFG D+ FV FFG+ AT+T +RIAA A V+P + +YPAW Sbjct: 185 DQDFGRNDSVFVDFFGIQTATITGLSRIAALANAKVIPAIPV-READNTVTLHFYPAWKS 243 Query: 241 YPGEDIVAATRRMNAFIEDRVREHPAEYFWAHKRFKTRPPGEPDVY 286 +PGED A +RMN FIEDRVREHP +YFW HKRFKTRP G PD Y Sbjct: 244 FPGEDAKADAQRMNRFIEDRVREHPEQYFWLHKRFKTRPEGSPDFY 289 >NMA1630 [M] COG1560 Lauroyl/myristoyl acyltransferase NmA Neisseria meningitidis Z2491 Length = 289 Score = 231 bits (590), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 117/286 (40%), Positives = 170/286 (59%), Gaps = 6/286 (2%) Query: 4 IMWLLHWLPLPILGRLGEGIGSLLYLYMRPRRHIALTNLRLCFPEKTEEERVSIAREHFR 63 ++++L +LP +L +L + G L YL ++PRR I NL CFPE ++R ++ ++HF+ Sbjct: 7 VLYVLQFLPFALLHKLADLTGLLAYLLVKPRRRIGEINLAKCFPEWDGKKRKTVLKQHFK 66 Query: 64 LFARSALERGILWWAPISRLRRLIQVEPGMPLD-TFAKG-PTILLAPHFVCLEIPGATLG 121 A+ LE G+ W+AP RL+ L++ LD A G I+L PHF E+ A Sbjct: 67 HMAKLMLEYGLYWYAPAGRLKSLVRYRNKHYLDDALAAGEKVIILYPHFTAFEM--AVYA 124 Query: 122 VFSEYSACTIYTKQRNDVIDRALLKGRLRFRPATLLAREQGVKPIIRAMRKG-LPFLMLP 180 + + ++Y+ Q+N ++D +LKGR R+ L+ R +G++ +++ RK PFL LP Sbjct: 125 LNQDVPLISMYSHQKNKILDEQILKGRNRYHNVFLIGRTEGLRALVKQFRKSSAPFLYLP 184 Query: 181 DMDFGIRDAEFVPFFGVPAATLTATARIAAATGAAVVPVVCTFLPGYKGWKATYYPAWTD 240 D DFG D+ FV FFG+ AT+T +RIAA A V+P + +YPAW Sbjct: 185 DQDFGRNDSVFVDFFGIRTATITGLSRIAALANAKVIPAIPV-READNTVTLHFYPAWES 243 Query: 241 YPGEDIVAATRRMNAFIEDRVREHPAEYFWAHKRFKTRPPGEPDVY 286 +P ED A +RMN FIE+RVREHP +YFW HKRFKTRP G PD Y Sbjct: 244 FPSEDAQADAQRMNRFIEERVREHPEQYFWLHKRFKTRPEGSPDFY 289 >PA3242 [M] COG1560 Lauroyl/myristoyl acyltransferase Pae Pseudomonas aeruginosa Length = 312 Score = 189 bits (481), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 112/279 (40%), Positives = 158/279 (56%), Gaps = 6/279 (2%) Query: 11 LPLPILGRLGEGIGSLLYLYMRPRRHIALTNLRLCFPEKTEEERVSIAREHFRLFARSAL 70 LP P+L LG G+G+L+Y + RR IA NL LCFPEK+ ER + +E+F + Sbjct: 31 LPYPVLLMLGRGLGALMYRLVGSRREIAARNLELCFPEKSPAERERLLKENFASSGIAFF 90 Query: 71 ERGILWWAPISRLRRLIQVEPGMPL-DTFAKGP-TILLAPHFVCLEIPGATLGVFSEYSA 128 E + WW P +RL RL +E L + A+G IL+A HF LEI A LG ++ Sbjct: 91 EMAMSWWWPKARLARLAHIEGLEHLREAQAQGEGVILMALHFTTLEIGAALLGQV--HTI 148 Query: 129 CTIYTKQRNDVIDRALLKGRLRFR-PATLLAREQGVKPIIRAMRKGLPFLMLPDMDFGIR 187 +Y + N V D +GR R AT + RE V+ +++ +R G PD D+G + Sbjct: 149 DGMYREHDNPVFDYVQRRGRERHNLDATAIERED-VRSMLKVLRGGRAIWYAPDQDYGAK 207 Query: 188 DAEFVPFFGVPAATLTATARIAAATGAAVVPVVCTFLPGYKGWKATYYPAWTDYPGEDIV 247 + FVP FG+PAAT+TAT + A A V+P + L G++ T +P D+PGE Sbjct: 208 QSLFVPLFGIPAATVTATTKFARLGRARVLPFTQSRLADGSGYRLTIHPPLEDFPGESEE 267 Query: 248 AATRRMNAFIEDRVREHPAEYFWAHKRFKTRPPGEPDVY 286 A R+N ++E VR+ P +Y WAH+RFKTRPPGE +Y Sbjct: 268 ADCLRINQWVERCVRQQPEQYLWAHRRFKTRPPGEAKLY 306 >ddg [M] COG1560 Lauroyl/myristoyl acyltransferase Eco Escherichia coli K12 Length = 328 Score = 156 bits (395), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 95/291 (32%), Positives = 149/291 (51%), Gaps = 14/291 (4%) Query: 2 LAIMWLLHWLPLPILGRLGEGIGSLLYLYMRPRRHIALTNLRLCFPEKTEEERVSIAREH 61 L ++WL LP P+L LG IG++ +++ R IA NL LCFP+ + EER + E+ Sbjct: 45 LGVLWLWVQLPYPVLCFLGTRIGAMARPFLKRRESIARKNLELCFPQHSAEEREKMIAEN 104 Query: 62 FRLFARSALERGILWWAPISRLRRLIQVEPGMPLDTFAKGP-----TILLAPHFVCLEIP 116 FR + +E G+ W+ P SR+R+ VE LD + +++ HF+ LE+ Sbjct: 105 FRSLGMALVETGMAWFWPDSRVRKWFDVE---GLDNLKRAQMQNRGVMVVGVHFMSLELG 161 Query: 117 GATLGVFSEYSACTIYTKQRNDVIDRALLKGRLRFRPATLLAREQGVKPIIRAMRKGLPF 176 G +G+ A Y N +++ +GR+R A ++ R ++ I+ A++KG Sbjct: 162 GRVMGLCQPMMAT--YRPHNNQLMEWVQTRGRMRSNKA-MIGRNN-LRGIVGALKKGEAV 217 Query: 177 LMLPDMDFGIRDAEFVPFFGVP-AATLTATARIAAATGAAVVPVVCTFLPGYKGWKATYY 235 PD D+G + + F PFF V AT T ++ +GAA++ V Y G++ Sbjct: 218 WFAPDQDYGRKGSSFAPFFAVENVATTNGTYVLSRLSGAAMLTVTMVRKADYSGYRLFIT 277 Query: 236 PAWTDYPGEDIVAATRRMNAFIEDRVREHPAEYFWAHKRFKTRPPGEPDVY 286 P YP ++ AA MN IE + P +Y W H+RFKTRP GE +Y Sbjct: 278 PEMEGYPTDENQAAA-YMNKIIEKEIMRAPEQYLWIHRRFKTRPVGESSLY 327