BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0009.p (384 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMA1661 [L] COG0389 Nucleotidyltransferase/DNA polymerase involv... 215 1e-55 SMa2355 [L] COG0389 Nucleotidyltransferase/DNA polymerase involv... 210 4e-54 CC2466 [L] COG0389 Nucleotidyltransferase/DNA polymerase involve... 200 6e-51 SPy1846 [L] COG0389 Nucleotidyltransferase/DNA polymerase involv... 199 1e-50 lin2082 [L] COG0389 Nucleotidyltransferase/DNA polymerase involv... 198 2e-50 >NMA1661 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair NmA Neisseria meningitidis Z2491 Length = 352 Score = 215 bits (548), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 138/372 (37%), Positives = 192/372 (51%), Gaps = 31/372 (8%) Query: 3 NDRRIAHLDMDAFYASVELLRYPDLRGQAVVIGGGSATRPVELPDGTRQYFRMRDYAGRG 62 + R+I H+DMDAFYASVEL P L+G+ VV+ A R Sbjct: 2 SSRKIIHIDMDAFYASVELREQPHLKGRPVVVAWEGA---------------------RS 40 Query: 63 VVTTSTYEARALGVFSAMGIMKAAQLAPDAILLPTDFEAYRKYSRLFKEAVRNIAPLIED 122 V+ ++YEAR G+ SAM + A +L P A+ +P F+ YR+ S R LIE Sbjct: 41 VICAASYEARQFGLHSAMSVATAKRLCPQAVYVPPHFDLYRQVSAQIHAVFRRYTDLIEP 100 Query: 123 RGIDEIYIDLSAWSDTAP---EVARQIKDAVHAATSLTCSIGVAPNKMLAKISSELDKPN 179 +DE Y+D++ P EVA++I+ A+ A T LT S G+APNK LAKI+S+ KPN Sbjct: 101 LSLDEAYLDVTRNFKNIPYASEVAKEIRAAIFAETGLTASAGIAPNKFLAKIASDWRKPN 160 Query: 180 GLTILTPADIERRIWPLPVRKINGIGPKAAEKLSALGIDTVADLARAAPDLLRAHFGRSY 239 G +L P + + LP+ KI G+G +K+ +LG+ T DL R L HFGR Y Sbjct: 161 GQFVLPPHKVMAFLETLPLGKIPGVGKVTLKKMQSLGMQTAGDLRRFERGELLNHFGR-Y 219 Query: 240 AEWLGRVAQGVDDRPVQTYSEPKSISRETTFERDLHARADRAQLSEIFTALCVKLAADLD 299 L +A+G D+RPV+ E IS E T DL L L L + Sbjct: 220 GYRLYDLARGTDERPVKAERECLQISTEITLPEDLPLEQAAGHLPH----LAEDLWRQIT 275 Query: 300 RKGYVGRTIGIKLKYADFRGVTRDVTLPSPTGDAAAIRQAAGECLKRVP--LDKKLRLLG 357 RK +++ +KLK DFR +TR +T S D A+ QAA + RVP + RL+G Sbjct: 276 RKNVEAQSVTLKLKTYDFRIITRTLTYSSVLPDCTALLQAAQMLMARVPPQTEDAFRLIG 335 Query: 358 VRVGALSKKDEQ 369 + VG L K++Q Sbjct: 336 IGVGHLVPKNQQ 347 >SMa2355 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair Sme Sinorhizobium meliloti Length = 379 Score = 210 bits (535), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 138/376 (36%), Positives = 200/376 (53%), Gaps = 41/376 (10%) Query: 5 RRIAHLDMDAFYASVELLRYPDLRGQAVVIGGGSATRPVELPDGTRQYFRMRDYAGRGVV 64 R+I H+DMDAFYASVE P+LRG+ V +G A RGVV Sbjct: 27 RKIIHIDMDAFYASVEQRDNPELRGKPVAVGYPEA---------------------RGVV 65 Query: 65 TTSTYEARALGVFSAMGIMKAAQLAPDAILLPTDFEAYRKYSRLFKEAVRNIAPLIEDRG 124 ++YEAR GV SAM + A + P+ I +P F+ YR SR + PL+E Sbjct: 66 AAASYEARKFGVHSAMPSVTAKRKCPELIFVPHRFDVYRAVSRQIQAIFAEYTPLVEPLS 125 Query: 125 IDEIYIDLSA---WSDTAPEVARQIKDAVHAATSLTCSIGVAPNKMLAKISSELDKPNGL 181 +DE Y+D++ A E+A +I+ + A T LT S GV+ NK LAK++S+ KP+GL Sbjct: 126 LDEAYLDVTENFRGLKLATEIAEEIRGRIRAETHLTASAGVSYNKFLAKMASDQRKPDGL 185 Query: 182 TILTPADIERRIWPLPVRKINGIGPKAAEKLSALGIDTVADLARAAPDLLRAHFGRS--Y 239 ++TP + LPV+K +G+GP AEK+ LGI+T ADL L+ HFG+S Y Sbjct: 186 FVITPKHGPDFVQALPVKKFHGVGPATAEKMKRLGIETGADLKSRDLAFLQQHFGKSGPY 245 Query: 240 AEWLGRVAQGVDDRPVQTYSEPKSISRETTFERDLH----ARADRAQLSEIFTALCVKLA 295 W +A+G+D+R V+ KSI E TF D+H ARA L + C Sbjct: 246 FYW---IARGIDERKVKPDRIRKSIGAEDTFREDVHDLETARAGLKPLIDKVWHYC---- 298 Query: 296 ADLDRKGYVGRTIGIKLKYADFRGVTRDVTLPSPTGDAAAIRQAAGECLKRV-PLDKKLR 354 + G G+T+ +K+K+ADF +TR T+ +P A + + A L + P K +R Sbjct: 299 ---EASGIRGKTMTLKVKWADFTQITRSKTIVAPIASVAEMSEIAELLLSPIFPAPKGIR 355 Query: 355 LLGVRVGALSKKDEQA 370 LLGV + +L D+++ Sbjct: 356 LLGVTLSSLDTVDDRS 371 >CC2466 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair Ccr Caulobacter vibrioides Length = 418 Score = 200 bits (508), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 135/355 (38%), Positives = 183/355 (51%), Gaps = 30/355 (8%) Query: 7 IAHLDMDAFYASVELLRYPDLRGQAVVIGGGSATRPVELPDGTRQYFRMRDYAGRGVVTT 66 IAH+D DAFYASVE P LR V+IGGG RGVVTT Sbjct: 38 IAHMDCDAFYASVEKRDDPSLRDLPVIIGGGK----------------------RGVVTT 75 Query: 67 STYEARALGVFSAMGIMKAAQLAPDAILLPTDFEAYRKYSRLFKEAVRNIAPLIEDRGID 126 + Y AR G SAM + KA +L PDA+++ +F Y++ SR E + + PLI+ +D Sbjct: 76 ACYIARMSGAKSAMPMFKALKLCPDAVVIKPNFAKYKEESRRIHEKLDRLTPLIQPLSLD 135 Query: 127 EIYIDLSA----WSDTAPEVARQIKDAVHAATSLTCSIGVAPNKMLAKISSELDKPNGLT 182 E +IDL+ T ++ +++ + LT S+G+APNK LAKI+SELDKP G + Sbjct: 136 EAWIDLTGTERLHGATPAQMLARLQAEIERDIGLTVSVGLAPNKFLAKIASELDKPRGFS 195 Query: 183 ILTPADIERRIWPLPVRKINGIGPKAAEKLSALGIDTVADLARAAPDLLRAHFGRSYAEW 242 + A+ + + PV + G+GP L+ +G+ TV D+A A LL G S Sbjct: 196 AIGAAEAQSFLANKPVNILPGVGPATVASLAEIGLRTVGDIAAADLKLLANRLG-SGGMR 254 Query: 243 LGRVAQGVDDRPVQTYSEPKSISRETTFERDLHARADRAQLSEIFTALCVKLAADLDRKG 302 L R+A G D R V K+IS ETTF DLH R D L + LC K+A ++G Sbjct: 255 LHRLAHGQDSRIVDPDQARKTISAETTFNDDLHKRED---LEDELWPLCEKVAKQARQEG 311 Query: 303 YVGRTIGIKLKYADFRGVTRDVTLPSPTGDAAAIRQAAGECLKRVPLDKKLRLLG 357 GR +KL+ DF+ TR TL PT A + Q A E L P RL+G Sbjct: 312 VAGRVATLKLRTPDFKIHTRRRTLAVPTQTARTLFQVARELLSAEPRGLAYRLIG 366 >SPy1846 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair Spy Streptococcus pyogenes M1 GAS Length = 364 Score = 199 bits (505), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 134/374 (35%), Positives = 206/374 (55%), Gaps = 31/374 (8%) Query: 1 MAND--RRIAHLDMDAFYASVELLRYPDLRGQAVVIGGGSATRPVELPDGTRQYFRMRDY 58 + ND R+I H+DMDAF+A+VE P L+G+ VVIG R+ Sbjct: 6 LINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKDP-----------------RET 48 Query: 59 AGRGVVTTSTYEARALGVFSAMGIMKAAQLAPDAILLPTDFEAYRKYSRLFKEAVRNIAP 118 GRGVV+T YEAR G+ SAM +A + P AI + ++E YR + + Sbjct: 49 GGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRIFKRYTD 108 Query: 119 LIEDRGIDEIYIDLSAWS---DTAPEVARQIKDAVHAATSLTCSIGVAPNKMLAKISSEL 175 ++E IDE Y+D++ +A ++A+ I+ + LTCS GV+ NK LAK++S+ Sbjct: 109 VVEPMSIDEAYLDVTDNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKFLAKLASDF 168 Query: 176 DKPNGLTILTPADIERRIWPLPVRKINGIGPKAAEKLSALGIDTVADLARAAPDL-LRAH 234 +KP+GLT++ D + LP+ K +G+G K+ +KL +GI T DL A P++ L H Sbjct: 169 EKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVKKLHDMGIYTGQDLL-AVPEMTLIDH 227 Query: 235 FGRSYAEWLGRVAQGVDDRPVQTYSEPKSISRETTFERDLHARAD-RAQLSEIFTALCVK 293 FGR + L R A+G+ + PV+ KSI E T+ + L+ D +A++S+ + Sbjct: 228 FGR-FGFDLYRKARGISNSPVKYDRIRKSIGSERTYAKLLYQETDIKAEISKNVK----R 282 Query: 294 LAADLDRKGYVGRTIGIKLKYADFRGVTRDVTLPSPTGDAAAIRQAAGECLKRVPLD-KK 352 +AA L +G+TI +K++YADF +T+ VTLP T +AA I Q AG+ + + Sbjct: 283 VAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFDSLSENPAG 342 Query: 353 LRLLGVRVGALSKK 366 +RLLGV + L K Sbjct: 343 IRLLGVTMTNLEDK 356 >lin2082 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair Lin Listeria innocua Length = 356 Score = 198 bits (503), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 129/368 (35%), Positives = 193/368 (52%), Gaps = 30/368 (8%) Query: 1 MANDRRIAHLDMDAFYASVELLRYPDLRGQAVVIGGGSATRPVELPDGTRQYFRMRDYAG 60 M R+I H+DMDAFYASVE +P+ RG+ ++IGG D Sbjct: 1 MDTSRKIIHIDMDAFYASVEQRDHPEFRGKPLIIGG--------------------DPNK 40 Query: 61 RGVVTTSTYEARALGVFSAMGIMKAAQLAPDAILLPTDFEAYRKYSRLFKEAVRNIAPLI 120 RGVV T +YEAR GV SAM +AA+L P+ I + + Y + S +E +I Sbjct: 41 RGVVATCSYEARKFGVHSAMPTRQAAKLCPNGIFIHGNMAHYVEVSNQIREIFSRYTDII 100 Query: 121 EDRGIDEIYIDLSAWSD---TAPEVARQIKDAVHAATSLTCSIGVAPNKMLAKISSELDK 177 E +DE Y+D++ +A VAR+I+ ++ LT S GV+ NK +AKI+S+ K Sbjct: 101 EPLSLDEAYLDVTENKKGMKSATMVAREIQQTIYRELGLTASAGVSFNKFIAKIASDFKK 160 Query: 178 PNGLTILTPADIERRIWPLPVRKINGIGPKAAEKLSALGIDTVADLARAAP-DLLRAHFG 236 P G+T++ P + E + +PV K G+G AEKL LGI+T ADL + + DL+R Sbjct: 161 PAGITVVAPEEAEAFLEQIPVTKFYGVGKVTAEKLHRLGIETGADLKKWSEWDLIRELHK 220 Query: 237 RSYAEWLGRVAQGVDDRPVQTYSEPKSISRETTFERDLHARADRAQLSEIFTALCVKLAA 296 Y L R +G + V + + KS+ +ETTFE ++ D L + K+ Sbjct: 221 HGYQ--LYRHVRGRSNNIVNPHRDRKSVGKETTFEFNV---LDNRILEQSLMKFAKKVEE 275 Query: 297 DLDRKGYVGRTIGIKLKYADFRGVTRDVTLPSPTGDAAAIRQAAGECLKRVPLDK-KLRL 355 L + G+T+ +KL+Y+DF +T+ +TL T DA I QAA L+ + +RL Sbjct: 276 RLIKLQKHGKTVVLKLRYSDFTTITKRLTLNEYTNDANQIYQAAALLLRESYKGQDSIRL 335 Query: 356 LGVRVGAL 363 +G+ V L Sbjct: 336 IGLTVTNL 343