BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0081.p (183 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2205 [L] COG0587 DNA polymerase III, alpha subunit Rso Ralsto... 214 8e-56 PA3640 [L] COG0587 DNA polymerase III, alpha subunit Pae Pseudom... 140 1e-33 NMB1827 [L] COG0587 DNA polymerase III, alpha subunit Nme Neisse... 130 2e-30 NMA0632 [L] COG0587 DNA polymerase III, alpha subunit NmA Neisse... 122 3e-28 YPO1059 [L] COG0587 DNA polymerase III, alpha subunit Ype Yersin... 121 7e-28 >RSc2205 [L] COG0587 DNA polymerase III, alpha subunit Rso Ralstonia solanacearum Length = 1173 Score = 214 bits (545), Expect = 8e-56, Method: Compositional matrix adjust. Identities = 107/184 (58%), Positives = 136/184 (73%), Gaps = 2/184 (1%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 VDG VR+D+ VKAAA DG ALA+TDLAN F +VRFYKEARGKGVKPI G D+WITN + Sbjct: 18 VDGNVRLDEAVKAAAADGMGALALTDLANAFGLVRFYKEARGKGVKPIVGADVWITNHDE 77 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEG--GNGLIA 118 R+KP RLL+L++N+ GYL LC +L++AWL+NQ++GRAEV EW +E GL+A Sbjct: 78 RDKPSRLLLLVRNKQGYLNLCMLLARAWLSNQHRGRAEVAPEWFGEPGVEEAPMATGLLA 137 Query: 119 LSGAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGA 178 LSGA GDIG A+ NGN A A A +W+++FP +FY+ELQRAG A E V+Q+V L A Sbjct: 138 LSGAMGGDIGMALANGNEALARKLATQWSQVFPASFYIELQRAGNAGTEAYVQQAVKLAA 197 Query: 179 KLGL 182 + L Sbjct: 198 SMQL 201 >PA3640 [L] COG0587 DNA polymerase III, alpha subunit Pae Pseudomonas aeruginosa Length = 1173 Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 74/179 (41%), Positives = 106/179 (59%), Gaps = 5/179 (2%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 VDGLVR+ + KA A G A+AVTD +N+ +V+FYK A G G+KPI G D+W+ + + Sbjct: 17 VDGLVRVKPLAKAVAGLGMPAVAVTDQSNMCSLVKFYKTAMGAGIKPICGADIWLASREE 76 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEGGNGLIALS 120 RL +L N GY L E++S+ W Q G + +W+ +E GLIALS Sbjct: 77 DGPLSRLSLLAMNAKGYRNLTELISRGWSEGQRNGEIIIERDWV-----KEAAEGLIALS 131 Query: 121 GAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGAK 179 A G+IG A+ +G A+AEA R W E+FP FY+E+QR + N E + +VAL ++ Sbjct: 132 AAKEGEIGHALLDGEEAKAEALLREWMEVFPERFYVEVQRTSRVNDEEHLHAAVALASR 190 >NMB1827 [L] COG0587 DNA polymerase III, alpha subunit Nme Neisseria meningitidis MC58 Length = 1144 Score = 130 bits (327), Expect = 2e-30, Method: Composition-based stats. Identities = 77/184 (41%), Positives = 109/184 (59%), Gaps = 8/184 (4%) Query: 2 DGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDADR 61 DG+VRI ++ A + G AL ++DL N F +V+FYK R G+KPI D+ I N Sbjct: 19 DGMVRIKKLIAKAQEYGLPALGISDLMNEFGLVKFYKACRSAGIKPIGAADVRIGNPDAP 78 Query: 62 EKPFRLLVLIKNRHGYLQLCEVLSQAWL-NNQYKGRAEVRMEWLDALRHQEGGN-GLIAL 119 +KPFR +++I+N GYL+L E+L+ A++ ++ AE+ EWL + G N GLI L Sbjct: 79 DKPFRAMLIIRNDAGYLRLSELLTAAYVGKDRNVHHAELNPEWL-----ENGDNSGLICL 133 Query: 120 SGAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQ-ANMEVQVRQSVALGA 178 SGA G++G + NGN A A ++A FP AFY+ELQR + E V SV L Sbjct: 134 SGAHYGEVGVNLLNGNEDAARTAALKYAAWFPDAFYMELQRLPERPEWEACVSGSVKLAE 193 Query: 179 KLGL 182 +LGL Sbjct: 194 ELGL 197 >NMA0632 [L] COG0587 DNA polymerase III, alpha subunit NmA Neisseria meningitidis Z2491 Length = 1144 Score = 122 bits (307), Expect = 3e-28, Method: Composition-based stats. Identities = 79/184 (42%), Positives = 110/184 (59%), Gaps = 8/184 (4%) Query: 2 DGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDADR 61 DG+VRI ++ A + G AL ++DL N F +V+FYK R G+KPI D+ I N Sbjct: 19 DGMVRIKKLIAKAQEYGLPALGISDLMNEFGLVKFYKACRSAGIKPIGAADVRIGNPDAP 78 Query: 62 EKPFRLLVLIKNRHGYLQLCEVLSQAWL-NNQYKGRAEVRMEWLDALRHQEGGN-GLIAL 119 +KPFR +++I+N GYL+L E+L+ A++ ++ AE+ EWL + G N GLI L Sbjct: 79 DKPFRAMLIIRNDAGYLRLSELLTAAYVGKDRNVHHAELNPEWL-----ENGDNSGLICL 133 Query: 120 SGAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQ-ANMEVQVRQSVALGA 178 SGA G++G + NGN A A A ++A FP AFYLELQR + E V SV L Sbjct: 134 SGAHYGEVGVNLLNGNEDAARAAALKYAAWFPDAFYLELQRLPERPEWEACVSGSVKLAE 193 Query: 179 KLGL 182 +LGL Sbjct: 194 ELGL 197 >YPO1059 [L] COG0587 DNA polymerase III, alpha subunit Ype Yersinia pestis Length = 1171 Score = 121 bits (304), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 69/182 (37%), Positives = 103/182 (56%), Gaps = 5/182 (2%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 +DGL +I +VK AA G ALA+TD NL +V+FY A G G+KPI G D ++ ++ Sbjct: 29 IDGLAKIGPLVKRAAALGMPALAITDFTNLCGLVKFYGSAHGAGIKPIIGADFYVQSEIL 88 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEGGNGLIALS 120 ++ L VL +N GY L ++S+A+ + +WL ++H+E GLI LS Sbjct: 89 GDELAHLTVLARNNEGYQNLTLLISEAYQRGYGAAGPIIDRDWL--IKHKE---GLILLS 143 Query: 121 GAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGAKL 180 G MGD+G+ + GN Q + C + E FP +YLEL R G+ + E + +VAL + Sbjct: 144 GGRMGDVGKFLLRGNQVQVDQCLAFYQEHFPDCYYLELIRTGRPDEENYLHAAVALATER 203 Query: 181 GL 182 GL Sbjct: 204 GL 205