BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0057.p (898 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2125 [E] COG0308 Aminopeptidase N Rso Ralstonia solanacearum 1139 0.0 PA3083 [E] COG0308 Aminopeptidase N Pae Pseudomonas aeruginosa 918 0.0 YPO1414 [E] COG0308 Aminopeptidase N Ype Yersinia pestis 868 0.0 ECs1015 [E] COG0308 Aminopeptidase N Ecs Escherichia coli O157:H7 859 0.0 ZpepN [E] COG0308 Aminopeptidase N EcZ Escherichia coli O157:H7 ... 857 0.0 >RSc2125 [E] COG0308 Aminopeptidase N Rso Ralstonia solanacearum Length = 905 Score = 1139 bits (2947), Expect = 0.0, Method: Compositional matrix adjust. Identities = 595/923 (64%), Positives = 689/923 (74%), Gaps = 45/923 (4%) Query: 1 MRTDTPQTIYRKDYAAPHYLADTVEMGFDLDPADTRVATRITMTRNPAAKSRDLVLFGEE 60 +RTDT TIYR+DY AP + D V + DL P TR+ +R+ MTR A L L GE Sbjct: 2 LRTDTAVTIYRQDYTAPAFRIDDVALEIDLVPERTRIVSRLRMTRLRAGAP--LTLVGEG 59 Query: 61 LELVALRLNGKLLTQAKGDFRIAGGVLTIPAAPAKV----VLEIETLVHPDRNTSLMGLY 116 LEL + L+G+ L + D G LTI AAPA+ LE+ T +P N+SLMGLY Sbjct: 60 LELAGVTLDGQALPGIQPD----GDTLTIEAAPAQADTAFTLELTTFCNPAANSSLMGLY 115 Query: 117 VSNGNFFTQCEAEGFRKITYFPDRPDVMAKFTVMLRADKARYPVLLSNGNLIEEGDLPDG 176 VSN NFFTQCEAEGFRKITYF DRPDVMA +TV LRA KA YPVLLSNGNL+ + DLPDG Sbjct: 116 VSNDNFFTQCEAEGFRKITYFLDRPDVMAVYTVTLRAAKADYPVLLSNGNLVSQRDLPDG 175 Query: 177 RHYAKWEDPFKKPSYLFALVAGNLVCQEETVRLHSGRDALLQVWVEEGNLDKTQHAMDSL 236 RH A W DPFKKPSYLFALVAG L C E + SG++ LLQVWVE +L KT+HAMDSL Sbjct: 176 RHEAVWHDPFKKPSYLFALVAGTLECIEARILSASGKEKLLQVWVEPHDLGKTRHAMDSL 235 Query: 237 KNSITWDVQRFGLDLDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPRIATDVDFAN 296 ++I WD QRFGL+LDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLAN ATDVDFAN Sbjct: 236 IHAIRWDEQRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANAETATDVDFAN 295 Query: 297 IEAVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFS-----------ADMIGSDS 345 IE+VVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFS + + S Sbjct: 296 IESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMAAQAAAQAGNAAAAAS 355 Query: 346 GRAVKRIDDVRVLRQAQFPEDAGPMAHPVRPDSYVEINNFYTVTVYEKGAEVVRMYQTLL 405 RAVKRI+DVR+LRQ QFPEDAGPMAHPVRPDSY EINNFYTVTVYEKGAEVVRMYQTLL Sbjct: 356 ARAVKRIEDVRLLRQVQFPEDAGPMAHPVRPDSYEEINNFYTVTVYEKGAEVVRMYQTLL 415 Query: 406 GRDGFRKGMDLYFERHDGQAVTCDDFRAAMADANGRDLSQFERWYSQAGTPQVQASVDYD 465 GR+ FRKGMDLYF+RHDGQAVTCDDFRAAMADANGRDL++F RWYSQAGTP V +D Sbjct: 416 GREAFRKGMDLYFQRHDGQAVTCDDFRAAMADANGRDLTRFGRWYSQAGTPVVAVEGRHD 475 Query: 466 AKRKTLTLTLEQSCPPT-----PGQKKKQPFHIPVAVGLLDAQGRDLALTLEGE-KKAGP 519 A +T TLTL Q C P G KQPFHIP A+GLLDAQGRDL L L GE A P Sbjct: 476 AATRTYTLTLRQRCEPVGIETADGSLHKQPFHIPFAIGLLDAQGRDLPLRLRGEPASAQP 535 Query: 520 -TTRVLELTKAKQSFRFVNVEQKPVPSLLRGFSAPVLLQYDYSDAELAFLMAHDSDAFNR 578 TTRVL+ T+A+Q+F F +V + P+PSLLR FSAPV+++Y Y+ +L FL+AHD+D FNR Sbjct: 536 LTTRVLDFTEAEQTFVFEDVAEAPLPSLLRNFSAPVVVEYGYTTGQLTFLLAHDADPFNR 595 Query: 579 WEAGQRLATRRLLNLTVAVQAARQSGHVVSVDTVLNNLEHDGALANALRATLRDEALDPA 638 WEAGQRLAT LL + VQ R + D AL ALRA L D +LDPA Sbjct: 596 WEAGQRLATDALLRMVADVQQGRTP-------------QVDPALVEALRAVLADASLDPA 642 Query: 639 FRELVLTLPSETMIAEQMEIIDPHAIHVARQFLRRSLARELREDLLAAYHANQTPGEYSP 698 FRE +L LP+ET +AE+M++ DP AIHVAR+ LRR+LA L + L AYH + T G Y+P Sbjct: 643 FREQMLILPAETYLAERMDVADPAAIHVARRALRRTLAEALGAEFLRAYHDSTTDGPYTP 702 Query: 699 DAASAGRRALKNVALSYLAELDDEQAMTLAQQQDQQANNMTDRLAALSAILNSAAPGKSE 758 DA SAG+RAL+N+AL YLAE + +A+ LA+QQ A +MTDR+ AL+A++NS APG+ Sbjct: 703 DAVSAGKRALRNIALGYLAEAESAEALALAEQQYTSAASMTDRMGALAALVNSYAPGREA 762 Query: 759 ALQRFYAEFEQEALVIDKWFTLQA----TARNADVNTVRTLAEHPAFTLKNPNRARSLIF 814 AL FY F +ALVIDKWF LQA A + TVR L HPAFTL+NPNRAR+LIF Sbjct: 763 ALADFYTRFADDALVIDKWFALQAMQPGAAGKPTLATVRALMAHPAFTLRNPNRARALIF 822 Query: 815 SFCNGNPSAFHAPDGNGYSFWAEQVIALNASNPQVAARLARSLDRWRKYSPALQEKMRLA 874 SFC+GNP+ FHA DG+GY+FWAEQV+AL+A NPQV+ARLARSLDRWRKY PAL+E M A Sbjct: 823 SFCSGNPAQFHAADGSGYAFWAEQVLALDAINPQVSARLARSLDRWRKYVPALREAMHDA 882 Query: 875 LQQVAAAPKLSRDVAEVVTKALA 897 L++VAA P LSRDV E+V KALA Sbjct: 883 LKRVAAHPSLSRDVREIVGKALA 905 >PA3083 [E] COG0308 Aminopeptidase N Pae Pseudomonas aeruginosa Length = 885 Score = 918 bits (2372), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/904 (53%), Positives = 610/904 (67%), Gaps = 26/904 (2%) Query: 1 MRTDTPQTIYRKDYAAPHYLADTVEMGFDLDPADTRVATRITMTRNP--AAKSRDLVLFG 58 MRT+ P+ I+ KDY AP YL D + F+L + V + + RNP A L+L G Sbjct: 1 MRTEQPKVIHLKDYQAPDYLIDETHLKFELFEDHSLVHAELKLRRNPERGAGLPPLLLHG 60 Query: 59 EELELVALRLNGKLLTQAKGDFRIAGGVLTIPAAPAKVVLEIETLVHPDRNTSLMGLYVS 118 ++LEL+AL L+G+ L D+++ L + A+ VL +HP+ NT+L GLY S Sbjct: 61 QQLELLALELDGQAL--GADDYQLDDEQLGVQPRQAEFVLRSTVRIHPESNTALEGLYKS 118 Query: 119 NGNFFTQCEAEGFRKITYFPDRPDVMAKFTVMLRADKARYPVLLSNGNLIEEGDLPDGRH 178 F TQCEAEGFRKITY+ DRPDVM++FT + A++ RYPVLLSNGN + G +GRH Sbjct: 119 GKMFCTQCEAEGFRKITYYLDRPDVMSRFTTTVSAEQQRYPVLLSNGNPVASGSEGNGRH 178 Query: 179 YAKWEDPFKKPSYLFALVAGNLVCQEETVRLHSGRDALLQVWVEEGNLDKTQHAMDSLKN 238 +A WEDPFKKP+YLFALVAG+L C E++ R S RD L+++VE N+DK QHAMDSLK Sbjct: 179 WATWEDPFKKPAYLFALVAGDLWCVEDSFRTMSQRDVALRIYVEPENIDKVQHAMDSLKK 238 Query: 239 SITWDVQRFGLDLDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPRIATDVDFANIE 298 S+ WD + +G + DLD FMIVAV DFNMGAMENKGLNIFN+ VLA ATD +E Sbjct: 239 SMRWDEEVYGREYDLDIFMIVAVNDFNMGAMENKGLNIFNSSCVLARAETATDAAHQRVE 298 Query: 299 AVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMIGSDSGRAVKRIDDVRVL 358 VV HEYFHNW+GNRVTCRDWFQLSLKEG TVFRD EFSADM + R VKR++DV L Sbjct: 299 GVVAHEYFHNWSGNRVTCRDWFQLSLKEGFTVFRDSEFSADM----NSRTVKRVEDVAFL 354 Query: 359 RQAQFPEDAGPMAHPVRPDSYVEINNFYTVTVYEKGAEVVRMYQTLLGRDGFRKGMDLYF 418 R QF EDAGPMAHPVRPDS++EI+NFYT+TVYEKG+EVVRM TLLG +GFRKG DLYF Sbjct: 355 RTNQFAEDAGPMAHPVRPDSFIEISNFYTLTVYEKGSEVVRMIHTLLGAEGFRKGSDLYF 414 Query: 419 ERHDGQAVTCDDFRAAMADANGRDLSQFERWYSQAGTPQVQASVDYDAKRKTLTLTLEQS 478 +RHDGQAVTCDDF AM DANG DL+QF+RWYSQ+GTP++ +YDA + TLT+ QS Sbjct: 415 QRHDGQAVTCDDFVKAMEDANGVDLTQFKRWYSQSGTPRLAVEGEYDAAARRYTLTVRQS 474 Query: 479 CPPTPGQKKKQPFHIPVAVGLLDAQGRDLALTLEGEKKAGPTTRVLELTKAKQSFRFVNV 538 CPPTPGQ K+PF IP+ +GLLD QG +L L LEGE A RVL +T+A+Q F FV V Sbjct: 475 CPPTPGQPSKEPFVIPLELGLLDGQGHELPLRLEGEAVAQGGNRVLAVTEAEQRFVFVEV 534 Query: 539 EQKPVPSLLRGFSAPVLLQYDYSDAELAFLMAHDSDAFNRWEAGQRLATRRLLNLTVAVQ 598 ++P+PSLLRGFSAPV L + YS +L FLM HDSD FNRWEAGQ+L+ + L L Q Sbjct: 535 PEQPLPSLLRGFSAPVKLSFPYSRDQLLFLMQHDSDGFNRWEAGQQLSVQVLQELIGQHQ 594 Query: 599 AARQSGHVVSVDTVLNNLEHDGALANALRATLRDEALDPAFRELVLTLPSETMIAEQMEI 658 Q L D L A R L DEALD A +L+LPSE + E E+ Sbjct: 595 RGEQ-------------LVLDPRLIEAYRTLLADEALDQAMVAEMLSLPSEAYLTEISEV 641 Query: 659 IDPHAIHVARQFLRRSLARELREDLLAAYHANQTPGE---YSPDAASAGRRALKNVALSY 715 D AIH AR+F R+ + L E L Y AN+ Y +A+ RR+L+N+ALSY Sbjct: 642 ADVDAIHAAREFARQRIGEALFEPLWQRYQANRKISRDTAYLAEASHIARRSLQNIALSY 701 Query: 716 LAELDDEQAMTLAQQQDQQANNMTDRLAALSAILNSAAPG-KSEALQRFYAEFEQEALVI 774 L+ E+ + +Q + +NMT+RL AL+ ++NS K +AL F F+ + LV+ Sbjct: 702 LSLSGREEILAACLEQYEGCDNMTERLTALAVLVNSGFEAEKGKALAMFADYFKDDPLVM 761 Query: 775 DKWFTLQA-TARNADVNTVRTLAEHPAFTLKNPNRARSLIFSFCNGNPSAFHAPDGNGYS 833 D+WF++QA + + V+ L +HPAFTLKNPN+ R+LI +F N N FH PDG GY Sbjct: 762 DQWFSVQAGSPLPGGLERVQELMQHPAFTLKNPNKVRALIGAFANQNLVNFHRPDGAGYR 821 Query: 834 FWAEQVIALNASNPQVAARLARSLDRWRKYSPALQEKMRLALQQVAAAPKLSRDVAEVVT 893 F A+QVI LNA NPQ+A+RL L RWRKY A Q MR L+++ A+ +LS DV EVV+ Sbjct: 822 FLADQVIVLNALNPQIASRLLVPLTRWRKYDEARQALMRGELERILASGELSSDVYEVVS 881 Query: 894 KALA 897 K+LA Sbjct: 882 KSLA 885 >YPO1414 [E] COG0308 Aminopeptidase N Ype Yersinia pestis Length = 871 Score = 868 bits (2244), Expect = 0.0, Method: Compositional matrix adjust. Identities = 463/896 (51%), Positives = 579/896 (64%), Gaps = 28/896 (3%) Query: 3 TDTPQTIYRKDYAAPHYLADTVEMGFDLDPADTRVATRITMTRNPAAKSRDLVLFGEELE 62 T PQ YR DY AP Y +++ F LD T V T ++ + L+L GE+L Sbjct: 2 TQQPQAKYRHDYRAPDYTITDIDLDFALDAQKTTV-TAVSKVKRQGTDVTPLILNGEDLT 60 Query: 63 LVALRLNGKLLTQAKGDFRIAGGVLTIPAAPAKVVLEIETLVHPDRNTSLMGLYVSNGNF 122 L+++ ++G QA +R L I PA L I +HP N++L GLY+S Sbjct: 61 LISVSVDG----QAWPHYRQQDNTLVIEQLPADFTLTIVNDIHPATNSALEGLYLSGEAL 116 Query: 123 FTQCEAEGFRKITYFPDRPDVMAKFTVMLRADKARYPVLLSNGNLIEEGDLPDGRHYAKW 182 TQCEAEGFR ITY+ DRPDV+A+FT + ADK+RYP LLSNGN + +G+L DGRH+ KW Sbjct: 117 CTQCEAEGFRHITYYLDRPDVLARFTTRIVADKSRYPYLLSNGNRVGQGELDDGRHWVKW 176 Query: 183 EDPFKKPSYLFALVAGNLVCQEETVRLHSGRDALLQVWVEEGNLDKTQHAMDSLKNSITW 242 EDPF KPSYLFALVAG+ ++ SGR+ L+++V+ GNLD+ AM SLKNS+ W Sbjct: 177 EDPFPKPSYLFALVAGDFDVLQDKFITRSGREVALEIFVDRGNLDRADWAMTSLKNSMKW 236 Query: 243 DVQRFGLDLDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPRIATDVDFANIEAVVG 302 D RFGL+ DLD +MIVAV FNMGAMENKGLN+FN+KYVLA ATD D+ NIEAV+G Sbjct: 237 DETRFGLEYDLDIYMIVAVDFFNMGAMENKGLNVFNSKYVLAKAETATDKDYLNIEAVIG 296 Query: 303 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMIGSDSGRAVKRIDDVRVLRQAQ 362 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFS+D+ R+V RI++VRV+R AQ Sbjct: 297 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL----GSRSVNRIENVRVMRAAQ 352 Query: 363 FPEDAGPMAHPVRPDSYVEINNFYTVTVYEKGAEVVRMYQTLLGRDGFRKGMDLYFERHD 422 F EDA PMAH +RPD +E+NNFYT+TVYEKG+EV+RM TLLG F+ GM LYFERHD Sbjct: 353 FAEDASPMAHAIRPDKVIEMNNFYTLTVYEKGSEVIRMMHTLLGEQQFQAGMRLYFERHD 412 Query: 423 GQAVTCDDFRAAMADANGRDLSQFERWYSQAGTPQVQASVDYDAKRKTLTLTLEQSCPPT 482 G A TCDDF AM D + DLS F RWYSQ+GTP + DYD +++ L + Q PT Sbjct: 413 GSAATCDDFVQAMEDVSNVDLSLFRRWYSQSGTPLLTVHDDYDVEKQQYHLFVSQKTLPT 472 Query: 483 PGQKKKQPFHIPVAVGLLDAQGRDLALTLEGEKKAGPTTRVLELTKAKQSFRFVNVEQKP 542 Q +K P HIP+ + L D++G + L G P VL +T+A+Q+F F NV QKP Sbjct: 473 ADQPEKLPLHIPLDIELYDSKGNVIPLQHNGL----PVHHVLNVTEAEQTFTFDNVAQKP 528 Query: 543 VPSLLRGFSAPVLLQYDYSDAELAFLMAHDSDAFNRWEAGQRLATRRLLNLTVAVQAARQ 602 +PSLLR FSAPV L Y YSD +L FLM H + F+RW+A Q L + L VA +Q Sbjct: 529 IPSLLREFSAPVKLDYPYSDQQLTFLMQHARNEFSRWDAAQSLLA-TYIKLNVAKYQQQQ 587 Query: 603 SGHVVSVDTVLNNLEHDGALANALRATLRDEALDPAFRELVLTLPSETMIAEQMEIIDPH 662 L +A+A RA L DE LDPA +LTLPSE +AE IDP Sbjct: 588 P------------LSLPAHVADAFRAILLDEHLDPALAAQILTLPSENEMAELFTTIDPQ 635 Query: 663 AIHVARQFLRRSLARELREDLLAAYHANQTPGEYSPDAASAGRRALKNVALSYLAELDDE 722 AI + + R LA+EL ++LLA Y AN TP Y + +RAL+N L+YLA D+E Sbjct: 636 AISTVHEAITRCLAQELSDELLAVYVANMTP-VYRIEHGDIAKRALRNTCLNYLAFGDEE 694 Query: 723 QAMTLAQQQDQQANNMTDRLAALSAILNSAAPGKSEALQRFYAEFEQEALVIDKWFTLQA 782 A L Q QA+NMTD LAAL+A + + P + E L F + + LV+DKWF LQA Sbjct: 695 FANKLVSSQYHQADNMTDSLAALAAAVAAQLPCRDELLAAFDVRWNHDGLVMDKWFALQA 754 Query: 783 TARNADVNT-VRTLAEHPAFTLKNPNRARSLIFSFCNGNPSAFHAPDGNGYSFWAEQVIA 841 T+ A+V VRTL +HPAF+L NPNR RSLI SF +GNP+AFHA DG+GY F E + Sbjct: 755 TSPAANVLVQVRTLLKHPAFSLSNPNRTRSLIGSFASGNPAAFHAADGSGYQFLVEILSD 814 Query: 842 LNASNPQVAARLARSLDRWRKYSPALQEKMRLALQQVAAAPKLSRDVAEVVTKALA 897 LN NPQVAARL L R ++Y Q MR AL+Q+ LS D+ E +TKALA Sbjct: 815 LNTRNPQVAARLIEPLIRLKRYDAGRQALMRKALEQLKTLDNLSGDLYEKITKALA 870 >ECs1015 [E] COG0308 Aminopeptidase N Ecs Escherichia coli O157:H7 Length = 870 Score = 859 bits (2219), Expect = 0.0, Method: Compositional matrix adjust. Identities = 460/897 (51%), Positives = 587/897 (65%), Gaps = 30/897 (3%) Query: 3 TDTPQTIYRKDYAAPHYLADTVEMGFDLDPADTRVATRITMTRNPAAKSRDLVLFGEELE 62 T PQ YR DY AP Y +++ FDLD T V T ++ A L L GE+L+ Sbjct: 2 TQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKT-VVTAVSQAVRHGASDAPLCLNGEDLK 60 Query: 63 LVALRLNGKLLTQAKGDFRIAGGVLTIPAAPAKVVLEIETLVHPDRNTSLMGLYVSNGNF 122 LV++ +N + T K + G L I P + L+I + P NT+L GLY S Sbjct: 61 LVSVHINDEPWTAWKEE----EGALVISNLPERFTLKIINEISPAANTALEGLYQSGDAL 116 Query: 123 FTQCEAEGFRKITYFPDRPDVMAKFTVMLRADKARYPVLLSNGNLIEEGDLPDGRHYAKW 182 TQCEAEGFR ITY+ DRPDV+A+FT + ADK +YP LLSNGN + +G+L +GRH+ +W Sbjct: 117 CTQCEAEGFRHITYYLDRPDVLARFTTKIIADKTKYPFLLSNGNRVAQGELENGRHWVQW 176 Query: 183 EDPFKKPSYLFALVAGNLVCQEETVRLHSGRDALLQVWVEEGNLDKTQHAMDSLKNSITW 242 +DPF KP YLFALVAG+ +T SGR+ L+++V+ GNLD+ AM SLKNS+ W Sbjct: 177 QDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKW 236 Query: 243 DVQRFGLDLDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPRIATDVDFANIEAVVG 302 D +RFGL+ DLD +MIVAV FNMGAMENKGLNIFN+KYVLA ATD D+ +IE V+G Sbjct: 237 DEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIG 296 Query: 303 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMIGSDSGRAVKRIDDVRVLRQAQ 362 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFS+D+ RAV RI++VR +R Q Sbjct: 297 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL----GSRAVNRINNVRTMRGLQ 352 Query: 363 FPEDAGPMAHPVRPDSYVEINNFYTVTVYEKGAEVVRMYQTLLGRDGFRKGMDLYFERHD 422 F EDA PMAHP+RPD +E+NNFYT+TVYEKGAEV+RM TLLG + F+KGM LYFERHD Sbjct: 353 FAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQLYFERHD 412 Query: 423 GQAVTCDDFRAAMADANGRDLSQFERWYSQAGTPQVQASVDYDAKRKTLTLTLEQSCPPT 482 G A TCDDF AM DA+ DLS F RWYSQ+GTP V DY+ + + TLT+ Q P T Sbjct: 413 GSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPVVTVKDDYNPETEQYTLTISQRTPAT 472 Query: 483 PGQKKKQPFHIPVAVGLLDAQGRDLALTLEGEKKAGPTTRVLELTKAKQSFRFVNVEQKP 542 P Q +KQP HIP A+ L D +G+ + L +K P VL +T+A+Q+F F NV +P Sbjct: 473 PDQAEKQPLHIPFAIELYDNEGKVIPL----QKGGHPVNSVLNVTQAEQTFVFDNVYFQP 528 Query: 543 VPSLLRGFSAPVLLQYDYSDAELAFLMAHDSDAFNRWEAGQR-LATRRLLNLTVAVQAAR 601 VP+LL FSAPV L+Y +SD +L FLM H + F+RW+A Q LAT LN+ A Sbjct: 529 VPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNV-----ARH 583 Query: 602 QSGHVVSVDTVLNNLEHDGALANALRATLRDEALDPAFRELVLTLPSETMIAEQMEIIDP 661 Q G +S+ +A+A RA L DE +DPA +LTLPS +AE +IIDP Sbjct: 584 QQGQPLSLPV---------HVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDP 634 Query: 662 HAIHVARQFLRRSLARELREDLLAAYHANQTPGEYSPDAASAGRRALKNVALSYLAELDD 721 AI R+ L R+LA EL ++LLA Y+AN EY + +R L+N L +LA + Sbjct: 635 IAIAEVREALTRTLATELADELLAIYNANYQ-SEYRVEHEDIAKRTLRNACLRFLAFGET 693 Query: 722 EQAMTLAQQQDQQANNMTDRLAALSAILNSAAPGKSEALQRFYAEFEQEALVIDKWFTLQ 781 A L +Q +ANNMTD LAALSA + + P + +Q + ++ Q+ LV+DKWF LQ Sbjct: 694 HLADVLVSKQYHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWHQDGLVMDKWFILQ 753 Query: 782 ATARNADV-NTVRTLAEHPAFTLKNPNRARSLIFSFCNGNPSAFHAPDGNGYSFWAEQVI 840 AT+ A+V TVR L +H +FT+ NPNR RSLI +F NP+AFHA DG+GY F E + Sbjct: 754 ATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAEDGSGYQFLVEMLT 813 Query: 841 ALNASNPQVAARLARSLDRWRKYSPALQEKMRLALQQVAAAPKLSRDVAEVVTKALA 897 LN+ NPQVA+RL L R ++Y QEKMR AL+Q+ LS D+ E +TKALA Sbjct: 814 DLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA 870 >ZpepN [E] COG0308 Aminopeptidase N EcZ Escherichia coli O157:H7 EDL933 Length = 870 Score = 857 bits (2215), Expect = 0.0, Method: Compositional matrix adjust. Identities = 459/897 (51%), Positives = 586/897 (65%), Gaps = 30/897 (3%) Query: 3 TDTPQTIYRKDYAAPHYLADTVEMGFDLDPADTRVATRITMTRNPAAKSRDLVLFGEELE 62 T PQ YR DY AP Y +++ FDLD T V T ++ A L L GE+L+ Sbjct: 2 TQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKT-VVTAVSQAVRHGASDAPLCLNGEDLK 60 Query: 63 LVALRLNGKLLTQAKGDFRIAGGVLTIPAAPAKVVLEIETLVHPDRNTSLMGLYVSNGNF 122 LV++ +N + T K + G L I P + L+I + P NT+L GLY S Sbjct: 61 LVSVHINDEPWTAWKEE----EGALVISNLPERFTLKIINEISPAANTALEGLYQSGDAL 116 Query: 123 FTQCEAEGFRKITYFPDRPDVMAKFTVMLRADKARYPVLLSNGNLIEEGDLPDGRHYAKW 182 TQCEAEGFR ITY+ DRPDV+A+FT + ADK +YP LLSNGN + +G+L +GRH+ +W Sbjct: 117 CTQCEAEGFRHITYYLDRPDVLARFTTKIIADKTKYPFLLSNGNRVAQGELENGRHWVQW 176 Query: 183 EDPFKKPSYLFALVAGNLVCQEETVRLHSGRDALLQVWVEEGNLDKTQHAMDSLKNSITW 242 +DPF KP YLFALVAG+ +T SGR+ L+++V+ GNLD+ AM SLKNS+ W Sbjct: 177 QDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKW 236 Query: 243 DVQRFGLDLDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPRIATDVDFANIEAVVG 302 D +RFGL+ DLD +MIVAV FNMGAMENKGLNIFN+KYVLA ATD D+ +IE V+G Sbjct: 237 DEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIG 296 Query: 303 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMIGSDSGRAVKRIDDVRVLRQAQ 362 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFS+D+ RAV RI++VR +R Q Sbjct: 297 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL----GSRAVNRINNVRTMRGLQ 352 Query: 363 FPEDAGPMAHPVRPDSYVEINNFYTVTVYEKGAEVVRMYQTLLGRDGFRKGMDLYFERHD 422 F EDA PMAHP+RPD +E+NNFYT+TVYEKGAEV+RM LLG + F+KGM LYFERHD Sbjct: 353 FAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHXLLGEENFQKGMQLYFERHD 412 Query: 423 GQAVTCDDFRAAMADANGRDLSQFERWYSQAGTPQVQASVDYDAKRKTLTLTLEQSCPPT 482 G A TCDDF AM DA+ DLS F RWYSQ+GTP V DY+ + + TLT+ Q P T Sbjct: 413 GSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPVVTVKDDYNPETEQYTLTISQRTPAT 472 Query: 483 PGQKKKQPFHIPVAVGLLDAQGRDLALTLEGEKKAGPTTRVLELTKAKQSFRFVNVEQKP 542 P Q +KQP HIP A+ L D +G+ + L +K P VL +T+A+Q+F F NV +P Sbjct: 473 PDQAEKQPLHIPFAIELYDNEGKVIPL----QKGGHPVNSVLNVTQAEQTFVFDNVYFQP 528 Query: 543 VPSLLRGFSAPVLLQYDYSDAELAFLMAHDSDAFNRWEAGQR-LATRRLLNLTVAVQAAR 601 VP+LL FSAPV L+Y +SD +L FLM H + F+RW+A Q LAT LN+ A Sbjct: 529 VPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNV-----ARH 583 Query: 602 QSGHVVSVDTVLNNLEHDGALANALRATLRDEALDPAFRELVLTLPSETMIAEQMEIIDP 661 Q G +S+ +A+A RA L DE +DPA +LTLPS +AE +IIDP Sbjct: 584 QQGQPLSLPV---------HVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDP 634 Query: 662 HAIHVARQFLRRSLARELREDLLAAYHANQTPGEYSPDAASAGRRALKNVALSYLAELDD 721 AI R+ L R+LA EL ++LLA Y+AN EY + +R L+N L +LA + Sbjct: 635 IAIAEVREALTRTLATELADELLAIYNANYQ-SEYRVEHEDIAKRTLRNACLRFLAFGET 693 Query: 722 EQAMTLAQQQDQQANNMTDRLAALSAILNSAAPGKSEALQRFYAEFEQEALVIDKWFTLQ 781 A L +Q +ANNMTD LAALSA + + P + +Q + ++ Q+ LV+DKWF LQ Sbjct: 694 HLADVLVSKQYHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWHQDGLVMDKWFILQ 753 Query: 782 ATARNADV-NTVRTLAEHPAFTLKNPNRARSLIFSFCNGNPSAFHAPDGNGYSFWAEQVI 840 AT+ A+V TVR L +H +FT+ NPNR RSLI +F NP+AFHA DG+GY F E + Sbjct: 754 ATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAEDGSGYQFLVEMLT 813 Query: 841 ALNASNPQVAARLARSLDRWRKYSPALQEKMRLALQQVAAAPKLSRDVAEVVTKALA 897 LN+ NPQVA+RL L R ++Y QEKMR AL+Q+ LS D+ E +TKALA Sbjct: 814 DLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA 870