BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0016.0027.p         (368 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PA3079 [R] COG1033 Predicted exporters of the RND superfamily Pa...   238   1e-62
MJ1562 [R] COG1033 Predicted exporters of the RND superfamily Mj...    62   3e-09
TP0790 [R] COG1033 Predicted exporters of the RND superfamily Tp...    61   4e-09
BB0252 Non COG                                                         61   5e-09

>PA3079 [R] COG1033 Predicted exporters of the RND superfamily Pae
           Pseudomonas aeruginosa
          Length = 793

 Score =  238 bits (607), Expect = 1e-62,   Method: Compositional matrix adjust.
 Identities = 143/368 (38%), Positives = 203/368 (55%), Gaps = 5/368 (1%)

Query: 1   VVITLLVLAGSAWYSHDRLVGTLQPGAPELHADARYNRDARWIADNYGNGLDWLTVILAT 60
           + I LL+L G  WY     +G L  GAPEL  D+RYN D  +I  NY    D L V++ T
Sbjct: 431 IAIALLMLGGGLWYGKHLKIGDLDQGAPELRPDSRYNLDNDFIIRNYSTSSDVLVVMVKT 490

Query: 61  PANSCDQVRFGRYQDQFDTVMRHVPGVLSVSSFADQMKIYNEGYNEGNPAMFTVPLDAGN 120
               C   +     D+    + +  GV S  S     K   +G NEGN    T+   + N
Sbjct: 491 SPEGCSTHQALAAMDELAWKLENTEGVQSAISMVTVSKQVIKGMNEGNLKWETL---SRN 547

Query: 121 YAALAVEIGRVRGFLSKDCNMLASHLFLADHKAATINGVIQAVKRYRDQHKLEGLEIRLA 180
              L   I R  G  + DC++    +FL DHKA T++  + AV+ +  ++  + L+ +LA
Sbjct: 548 QDVLNNSIARADGLYNTDCSLAPLLVFLNDHKAETLDRAVAAVQAFAAENDKDDLQFQLA 607

Query: 181 AGNAGVIAAVNDEVEKSELPMMLYVYGAIVLLVFAVYRDWRAIIACCLPLTVATFIGYAF 240
           AGNAG+ AA N+ +++SEL +++ VY  +  +    +R + A +   LPL + + +G A 
Sbjct: 608 AGNAGIEAATNEVIKQSELIILVLVYICVAAMCMITFRSFAATLCIVLPLILTSVLGNAL 667

Query: 241 MKQLQIGLTVATLPVMVLAVGIGVDYAFYIYNRLQLHLAAGLAIEEALHNAIQEVGIATI 300
           M  L IG+ VATLPV+ L VGIGVDY  YIY RL+  L  GL ++EA +  ++  G A +
Sbjct: 668 MAALGIGVKVATLPVIALGVGIGVDYGIYIYTRLESFLRMGLPLQEAYYETLRSTGKAVL 727

Query: 301 FTAITLAIGVATWSFSDLKFQADMGKLLAFMFLVNLIMAMTALPAFAVVLDKMFPRKSPI 360
           FT + LAIGVATW FS +KFQADMG +L FM L N+  A+  LPA A  L  + P K   
Sbjct: 728 FTGLCLAIGVATWIFSAIKFQADMGLMLTFMLLWNMFGALWLLPALARFL--INPAKLQA 785

Query: 361 KLNSALAH 368
           +  S  AH
Sbjct: 786 RKASLFAH 793


>MJ1562 [R] COG1033 Predicted exporters of the RND superfamily Mja
           Methanococcus jannaschii
          Length = 388

 Score = 61.6 bits (148), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 78/334 (23%), Positives = 144/334 (43%), Gaps = 48/334 (14%)

Query: 43  IADNYGNGLDWLTVILA-TPANSCDQV------RFGRYQDQFDTVMRHVPGVLSVSSFAD 95
           + D +G G D +T+ +   P++S D+V      R  +   + +  +R+V G+ SVSS  D
Sbjct: 65  VRDEFG-GTDVITICIKLKPSDSSDKVVDIRDPRVLKAIKELEDNLRYVDGITSVSSPVD 123

Query: 96  QMKIYNEGYNEGNPAMFTVPLDAGNYAALAVEIGRVRGFLSKDCNMLASHLFLADHKAAT 155
            +   N G          VP D          I  V+  L+K        +F +D+    
Sbjct: 124 IIIQKNNGI---------VPND----------IDTVKDILNKLPEDKRKRIFNSDYSMTV 164

Query: 156 INGVIQAVKRYRDQHKL-----------------EGLEIRLAAGNAGVIAAVNDEVEKSE 198
           +N    A     DQ KL                  G+E+ +A G   +   +++ +++S+
Sbjct: 165 VNAYTDA---GGDQKKLMRVMDDVNERIEETPFPPGVEV-IATGTPPMRKLMDELMKESQ 220

Query: 199 LPMMLYVYGAIVLLVFAVYRDWRAIIACCLPLTVATFIGYAFMKQLQIGLTVATLPVMVL 258
                     I++++   +R   + I   LP+ +A       M  L I L +AT  +  L
Sbjct: 221 SFTTTVGLIGILIILIIYFRKPLSSIMPLLPVLIAVIWTGGAMGLLDIPLDMATAGIGSL 280

Query: 259 AVGIGVDYAFYIYNRLQLHLAAGLAIEEALHNAIQEVGIATIFTAITLAIGVATWSFSDL 318
            +G+G+DY  ++ +R       G+ I++A+  A+ E G A + T  T  +G      + L
Sbjct: 281 ILGLGIDYGIHLMHRYDEERRKGMPIDKAIETAVVETGTAVMATTATTVVGFLALVLAPL 340

Query: 319 KFQADMGKLLAFMFLVNLIMAMTALPAFAVVLDK 352
              A++GK+ A      +++ +T LPA  V+ ++
Sbjct: 341 PMMANLGKVCALGISFCMVVVLTLLPALIVIEER 374


>TP0790 [R] COG1033 Predicted exporters of the RND superfamily Tpa
           Treponema pallidum
          Length = 888

 Score = 61.2 bits (147), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 50/200 (25%), Positives = 89/200 (44%), Gaps = 8/200 (4%)

Query: 158 GVIQAVKRYRDQHKLEGLEIRLAAGNAGVIAAVNDEVEKSELPMMLYVYGAIVLLVFAVY 217
           GVI+AVK++  ++  + +      G+  V  ++ND V +S+L  +++    + +++   Y
Sbjct: 691 GVIEAVKKFIRENFPQDVHAEFG-GSVLVEQSLNDLVVQSQLISLVFSLCVVFIIIAVHY 749

Query: 218 RDWRAIIACCLPLTVATFIGYAFMKQLQIGLTVATLPVMVLAVGIGVDYAFYI---YNRL 274
           R   A I   LPL V+  + +  M    I L + T  V   + GIGVDY  +    Y R 
Sbjct: 750 RSLFAGIIGTLPLGVSVLVNFGVMGFFGIKLNICTTMVAGFSSGIGVDYTIHYLAAYRRA 809

Query: 275 QLHLAAGLAIEEALHNAIQEVGIATIFTAITLAIGVATWSFSDLKFQADMGKLLAFMFLV 334
                    + +  + +    G A +F  +++  G A    S     AD G L+    L 
Sbjct: 810 WKECGGKDFLTQTFYGS----GRAILFNVLSVGSGFAVLMLSKFNVLADFGLLMVLAMLT 865

Query: 335 NLIMAMTALPAFAVVLDKMF 354
           + + ++T LP    V+   F
Sbjct: 866 SSVASLTLLPTLLNVVKPRF 885


>BB0252 Non COG
          Length = 767

 Score = 60.8 bits (146), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 36/138 (26%), Positives = 69/138 (50%)

Query: 196 KSELPMMLYVYGAIVLLVFAVYRDWRAIIACCLPLTVATFIGYAFMKQLQIGLTVATLPV 255
           K ++  ++   G+I LL+   ++  +  I   +P+  + F+ +A M+   I L  AT  +
Sbjct: 596 KEQVINIITTLGSITLLLMFFFKSIKTGIIIAIPVAWSVFLNFAVMRLFGITLNPATATI 655

Query: 256 MVLAVGIGVDYAFYIYNRLQLHLAAGLAIEEALHNAIQEVGIATIFTAITLAIGVATWSF 315
             +++G+GVDY+ + +N   L        + AL  +I  V       +I++ IG  T +F
Sbjct: 656 ASVSMGVGVDYSIHFFNTFILQYQKNQIYKTALLESIPNVFNGIFANSISVGIGFLTLTF 715

Query: 316 SDLKFQADMGKLLAFMFL 333
           S  K  + +G ++AF  L
Sbjct: 716 SSYKIISTLGAIIAFTML 733