BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0018.p (382 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0027 [E] COG2021 Homoserine acetyltransferase Rso Ralstonia s... 582 e-166 NMB0940 [E] COG2021 Homoserine acetyltransferase Nme Neisseria m... 507 e-143 NMA1136 [E] COG2021 Homoserine acetyltransferase NmA Neisseria m... 502 e-142 PA0390 [E] COG2021 Homoserine acetyltransferase Pae Pseudomonas ... 494 e-139 mlr3538 [E] COG2021 Homoserine acetyltransferase Mlo Mesorhizobi... 363 e-100 >RSc0027 [E] COG2021 Homoserine acetyltransferase Rso Ralstonia solanacearum Length = 403 Score = 582 bits (1501), Expect = e-166, Method: Compositional matrix adjust. Identities = 273/375 (72%), Positives = 322/375 (85%), Gaps = 5/375 (1%) Query: 2 SIGIVSPQVMHFAEPLPLQGGSALADYSLTYETYGTLNADKSNAVLVCHALNASHHVAGV 61 S+G+V P+ MHFAEPLPL+ GS L Y L ETYGTLNA++SNAVL+CHALNASHHVAGV Sbjct: 32 SVGLVVPERMHFAEPLPLRNGSQLVGYDLMVETYGTLNAERSNAVLICHALNASHHVAGV 91 Query: 62 YADDPDNVGWWDNMVGPGKSLDTDRFFVIGVNNLGSCFGSTGPMHANPATGKPYGADFPV 121 +A+ VGWWDNMVGPGK +DT+RFFVIGVNNLGSCFGSTGPM +P TG+PYGA FPV Sbjct: 92 HAEG--EVGWWDNMVGPGKPVDTNRFFVIGVNNLGSCFGSTGPMSPHPQTGQPYGARFPV 149 Query: 122 VTVEDWVNAQARLADRLGITCFAAVMGGSLGGMQALAWSMMYPDRLRHCLVIASTPKLSA 181 VTVEDWVNAQAR+ADR GI FAAVMGGSLGGMQALAWS+MYP+R+RHC+V+ASTPKLSA Sbjct: 150 VTVEDWVNAQARVADRFGIRQFAAVMGGSLGGMQALAWSLMYPERVRHCVVVASTPKLSA 209 Query: 182 QNIAFNDVARQAILTDPQYHGGDFYAHGVVPKNGLRVARMVGHITYLSDDDMAEKFGRDL 241 QNIAFN+VAR AIL+DP +HGGD+YAH V PK GLRVARM+GHITYLSD+DMAEKFGR+L Sbjct: 210 QNIAFNEVARSAILSDPDFHGGDYYAHNVKPKRGLRVARMIGHITYLSDEDMAEKFGREL 269 Query: 242 RSGQYQFGYGVDFEIESYLRYQGDKFSTYFDANTYLLITKALDYFDPAREFGGDLAKXPK 301 ++ +F + V+F++ESYLRYQGDKF+ YFDANTYLLIT+ALDYFDPA + G L + Sbjct: 270 KAEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDYFDPALAYEGSLT---R 326 Query: 302 ALACTKAKFLLVSFTTDWRFSPERSREMVQALVANKRRVSYAEIDAPHGHDAFLLDDARY 361 A+A T+A +L+VSFTTDWRF+P RSRE+V+AL+ NKR V+Y EIDAPHGHDAFLL+DARY Sbjct: 327 AVAHTRASYLVVSFTTDWRFAPARSRELVKALLDNKRPVTYGEIDAPHGHDAFLLEDARY 386 Query: 362 MKVVREYYGSIWTEL 376 +VR YY I E+ Sbjct: 387 HALVRAYYERIAQEI 401 >NMB0940 [E] COG2021 Homoserine acetyltransferase Nme Neisseria meningitidis MC58 Length = 379 Score = 507 bits (1305), Expect = e-143, Method: Compositional matrix adjust. Identities = 234/377 (62%), Positives = 295/377 (78%), Gaps = 3/377 (0%) Query: 2 SIGIVSPQVMHFAEPLPLQGGSALADYSLTYETYGTLNADKSNAVLVCHALNASHHVAGV 61 S+GIV PQ + F PL L+ G L + L ETYG LNA+K+NAVL+CHAL+ +HHVAG Sbjct: 6 SVGIVMPQKIPFEMPLVLENGKTLPRFDLMIETYGELNAEKNNAVLICHALSGNHHVAGR 65 Query: 62 YADDPDNVGWWDNMVGPGKSLDTDRFFVIGVNNLGSCFGSTGPMHANPATGKPYGADFPV 121 ++ + GWWDNMVGPGK +DT+RFFV+G+NNLG C GS+GP+ NP TG+ YGADFPV Sbjct: 66 HSAEDKYTGWWDNMVGPGKPIDTERFFVVGLNNLGGCDGSSGPLSINPETGREYGADFPV 125 Query: 122 VTVEDWVNAQARLADRLGITCFAAVMGGSLGGMQALAWSMMYPDRLRHCLVIASTPKLSA 181 VTV+DWV +QA LAD LGI +AA++GGSLGGMQAL W++ YP+R+RH LVIAS PKLS Sbjct: 126 VTVKDWVKSQAALADYLGIEQWAAIVGGSLGGMQALQWTISYPERVRHALVIASAPKLST 185 Query: 182 QNIAFNDVARQAILTDPQYHGGDFYAHGVVPKNGLRVARMVGHITYLSDDDMAEKFGRDL 241 QNIAFNDVARQAILTDP ++ G + +H VP GLR+ARM+GHITYL++D + +KFGRDL Sbjct: 186 QNIAFNDVARQAILTDPDFNEGHYRSHNTVPARGLRIARMMGHITYLAEDGLGKKFGRDL 245 Query: 242 RSGQYQFGYGVDFEIESYLRYQGDKFSTYFDANTYLLITKALDYFDPAREFGGDLAKXPK 301 RS YQ+G+GV+FE+ESYLRYQGDKF FDANTYLL+TKALDYFDPA +FG L + Sbjct: 246 RSNGYQYGFGVEFEVESYLRYQGDKFVGRFDANTYLLMTKALDYFDPAADFGDSLT---R 302 Query: 302 ALACTKAKFLLVSFTTDWRFSPERSREMVQALVANKRRVSYAEIDAPHGHDAFLLDDARY 361 AL KAKF + SF+TDWRF+PERS E+V+AL+A ++ V Y E+ + HGHDAFL++D Y Sbjct: 303 ALQNVKAKFFVASFSTDWRFAPERSHELVKALIAAQKSVQYIEVKSAHGHDAFLMEDEAY 362 Query: 362 MKVVREYYGSIWTELQQ 378 M+ V Y +++ E QQ Sbjct: 363 MRAVAAYMNNVYKECQQ 379 >NMA1136 [E] COG2021 Homoserine acetyltransferase NmA Neisseria meningitidis Z2491 Length = 379 Score = 502 bits (1293), Expect = e-142, Method: Compositional matrix adjust. Identities = 232/377 (61%), Positives = 294/377 (77%), Gaps = 3/377 (0%) Query: 2 SIGIVSPQVMHFAEPLPLQGGSALADYSLTYETYGTLNADKSNAVLVCHALNASHHVAGV 61 S+GIV+PQ + F PL L+ G L + L ETYG LNA+K+NAVL+CHAL+ +HHVAG Sbjct: 6 SVGIVTPQKIPFEMPLVLENGKTLPRFDLMIETYGELNAEKNNAVLICHALSGNHHVAGR 65 Query: 62 YADDPDNVGWWDNMVGPGKSLDTDRFFVIGVNNLGSCFGSTGPMHANPATGKPYGADFPV 121 ++ + GWWDNMVGPGK +DT+RFFV+G+NNLG C GS+GP+ NP TG+ YGADFPV Sbjct: 66 HSAEDKYTGWWDNMVGPGKPIDTERFFVVGLNNLGGCDGSSGPLSINPETGREYGADFPV 125 Query: 122 VTVEDWVNAQARLADRLGITCFAAVMGGSLGGMQALAWSMMYPDRLRHCLVIASTPKLSA 181 VTV+DWV +QA L D LGI +AAV+GGSLGGMQAL W++ YP+R+RH LVIAS PKLS Sbjct: 126 VTVKDWVKSQAALTDYLGIGQWAAVVGGSLGGMQALQWTISYPERVRHALVIASAPKLST 185 Query: 182 QNIAFNDVARQAILTDPQYHGGDFYAHGVVPKNGLRVARMVGHITYLSDDDMAEKFGRDL 241 QNIAFNDVARQAILTDP ++ G + + VP GLR+ARM+GHITYL++D + +KFGRDL Sbjct: 186 QNIAFNDVARQAILTDPDFNEGHYRSRNTVPARGLRIARMMGHITYLAEDGLGKKFGRDL 245 Query: 242 RSGQYQFGYGVDFEIESYLRYQGDKFSTYFDANTYLLITKALDYFDPAREFGGDLAKXPK 301 RS YQ+GYGV+FE+ESYLRYQGDKF FDANTYLL+TKALDYFDPA +FG L + Sbjct: 246 RSNGYQYGYGVEFEVESYLRYQGDKFVGRFDANTYLLMTKALDYFDPAADFGNSLT---R 302 Query: 302 ALACTKAKFLLVSFTTDWRFSPERSREMVQALVANKRRVSYAEIDAPHGHDAFLLDDARY 361 A+ +AKF + SF+TDWRF+PERS E+V+AL+A ++ V Y E+ + HGHDAFL++D Y Sbjct: 303 AVQDVQAKFFVASFSTDWRFAPERSHELVKALIAAQKSVQYIEVKSAHGHDAFLMEDEAY 362 Query: 362 MKVVREYYGSIWTELQQ 378 M+ V Y +++ E QQ Sbjct: 363 MRAVAAYMNNVYKECQQ 379 >PA0390 [E] COG2021 Homoserine acetyltransferase Pae Pseudomonas aeruginosa Length = 379 Score = 494 bits (1273), Expect = e-139, Method: Compositional matrix adjust. Identities = 236/372 (63%), Positives = 289/372 (77%), Gaps = 4/372 (1%) Query: 2 SIGIVSPQVMHFAEPLPLQGGSALADYSLTYETYGTLNADKSNAVLVCHALNASHHVAGV 61 S+G+VSPQ +HF EPL L G +LA+Y L ETYG LNA +SNAVL+CHAL+ HH AG Sbjct: 9 SVGLVSPQTLHFNEPLELTSGKSLAEYDLVIETYGELNATQSNAVLICHALSGHHHAAGY 68 Query: 62 YADDPDNVGWWDNMVGPGKSLDTDRFFVIGVNNLGSCFGSTGPMHANPATGKPYGADFPV 121 ++ D GWWD+ +GPGK +DT +FFV+ +NNLG C GS+GP NPATGK YGADFP+ Sbjct: 69 HSVDERKPGWWDSCIGPGKPIDTRKFFVVALNNLGGCNGSSGPASINPATGKVYGADFPM 128 Query: 122 VTVEDWVNAQARLADRLGITCFAAVMGGSLGGMQALAWSMMYPDRLRHCLVIASTPKLSA 181 VTVEDWV++QARLADRLGI +AAV+GGSLGGMQAL W++ YP+R+RHCL IAS PKLSA Sbjct: 129 VTVEDWVHSQARLADRLGIRQWAAVVGGSLGGMQALQWTISYPERVRHCLCIASAPKLSA 188 Query: 182 QNIAFNDVARQAILTDPQYHGGDFYAHGVVPKNGLRVARMVGHITYLSDDDMAEKFGRDL 241 QNIAFN+VARQAIL+DP++ GG F GV+PK GL++ARMVGHITYLSDD M KFGR L Sbjct: 189 QNIAFNEVARQAILSDPEFLGGYFQEQGVIPKRGLKLARMVGHITYLSDDAMGAKFGRVL 248 Query: 242 RSGQYQFG-YGVDFEIESYLRYQGDKFSTYFDANTYLLITKALDYFDPAREFGGDLAKXP 300 ++ + + + V+F++ESYLRYQG++FST FDANTYLL+TKALDYFDPA G DL Sbjct: 249 KTEKLNYDLHSVEFQVESYLRYQGEEFSTRFDANTYLLMTKALDYFDPAAAHGDDLV--- 305 Query: 301 KALACTKAKFLLVSFTTDWRFSPERSREMVQALVANKRRVSYAEIDAPHGHDAFLLDDAR 360 + L +A F L+SFTTDWRFSP RSRE+V AL+A K+ VSY EIDAP GHDAFL+ R Sbjct: 306 RTLEGVEADFCLMSFTTDWRFSPARSREIVDALIAAKKNVSYLEIDAPQGHDAFLMPIPR 365 Query: 361 YMKVVREYYGSI 372 Y++ Y I Sbjct: 366 YLQAFSGYMNRI 377 >mlr3538 [E] COG2021 Homoserine acetyltransferase Mlo Mesorhizobium loti Length = 389 Score = 363 bits (932), Expect = e-100, Method: Compositional matrix adjust. Identities = 183/370 (49%), Positives = 241/370 (65%), Gaps = 11/370 (2%) Query: 7 SPQVMHFA--EPLPLQGGSALADYSLTYETYGTLNADKSNAVLVCHALNASHHVAGVYAD 64 S V+ F +PL L G+ L+ + + Y+TYGTLN +SNA+LVCHAL HVA Sbjct: 17 SSPVLRFGADKPLKLDAGTLLSPFQIAYQTYGTLNDARSNAILVCHALTGDQHVANT--- 73 Query: 65 DP--DNVGWWDNMVGPGKSLDTDRFFVIGVNNLGSCFGSTGPMHANPATGKPYGADFPVV 122 +P GWW+ ++GPG+ +DT+RFFVI N +G C GSTGP NPATGKPYG D PV+ Sbjct: 74 NPVTGKPGWWEVLIGPGRIIDTNRFFVICSNVIGGCLGSTGPASTNPATGKPYGLDLPVI 133 Query: 123 TVEDWVNAQARLADRLGITCFAAVMGGSLGGMQALAWSMMYPDRLRHCLVIASTPKLSAQ 182 T+ D V AQ L D GI V+GGS+GGMQ L W+ YP+R+ L IA+ + S+Q Sbjct: 134 TIRDMVRAQQMLIDHFGIEKLFCVLGGSMGGMQVLEWASSYPERVFSALPIATGARHSSQ 193 Query: 183 NIAFNDVARQAILTDPQYHGGDFYAHGVVPKNGLRVARMVGHITYLSDDDMAEKFGRDLR 242 NIAF++V RQA++ DP +HGG ++ +G P+ GL VARM HITYLS+ + KFGR+L+ Sbjct: 194 NIAFHEVGRQAVMADPDWHGGKYFENGKRPEKGLAVARMAAHITYLSEAALHRKFGRNLQ 253 Query: 243 SGQ-YQFGYGVDFEIESYLRYQGDKFSTYFDANTYLLITKALDYFDPAREFGGDLAKXPK 301 + FG+ DF+IESYLR+QG F FDAN+YL +T+++DYFD A + GG LA Sbjct: 254 DREALTFGFDADFQIESYLRHQGMTFVDRFDANSYLYMTRSMDYFDLAADHGGRLA---D 310 Query: 302 ALACTKAKFLLVSFTTDWRFSPERSREMVQALVANKRRVSYAEIDAPHGHDAFLLDDARY 361 A A TK +F LVSFT+DW F E SR +V AL A VS+ EI+ GHDAFLLD+ Sbjct: 311 AFAGTKTRFCLVSFTSDWLFPTEESRSIVHALNAAGASVSFVEIETDRGHDAFLLDEPEL 370 Query: 362 MKVVREYYGS 371 + + GS Sbjct: 371 FAAINGFIGS 380