BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0140.p (258 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2643 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Rso R... 318 9e-87 AGl2129 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Atu A... 246 4e-65 NMA0927 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) NmA N... 243 4e-64 VC0987 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Vch Vi... 242 5e-64 NMB0718 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Nme N... 239 4e-63 >RSc2643 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Rso Ralstonia solanacearum Length = 371 Score = 318 bits (814), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 148/234 (63%), Positives = 179/234 (76%), Gaps = 5/234 (2%) Query: 1 VVHAMRYGSPSLPQVLDQLKQQGCTRILVLPAYPQYSGTTTASIFDAVFDHYRKVRNIPE 60 V AMRYG+PS+P V+ L++QG RILVLP YPQYSGTTTA+ FD VF ++RN PE Sbjct: 115 VACAMRYGNPSIPSVMQTLRKQGVERILVLPMYPQYSGTTTATAFDEVFRVMGQMRNQPE 174 Query: 61 LRLIRNYHDQDGYIQALRQSVLDHWEVNGRPD-----KLVMSFHGVPKRTLELGDPYHCE 115 LRL++++HD YI AL Q V +W +G PD KL++SFHGVP+RTLELGDPYHC Sbjct: 175 LRLVKHFHDHPAYINALHQQVGAYWAQHGAPDFARGDKLLLSFHGVPRRTLELGDPYHCA 234 Query: 116 CYKTARLLAQSLGLNDEQYLVTFQSRFGKAEWLQPYTAPTVQALGRQGVRRIDVMCPGFT 175 C KT RLL ++LGL QYLVTFQSRFG+AEWLQPYTAPT++ LGR G R+DV CPGF Sbjct: 235 CLKTGRLLGEALGLQPGQYLVTFQSRFGRAEWLQPYTAPTLEELGRVGTGRVDVFCPGFP 294 Query: 176 SDCLETLEEIAMEVKDEFLHAGGKEFHFIPCLNESPAWIAGMVEIVEQHLAGWP 229 +DCLETLEEIAME + F AGGK+FH+IPCLN+S WIAG+ +I + HL GWP Sbjct: 295 ADCLETLEEIAMEGQSTFRVAGGKDFHYIPCLNDSEPWIAGLADIAQAHLQGWP 348 >AGl2129 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 368 Score = 246 bits (628), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 113/226 (50%), Positives = 156/226 (69%), Gaps = 1/226 (0%) Query: 4 AMRYGSPSLPQVLDQLKQQGCTRILVLPAYPQYSGTTTASIFDAVFDHYRKVRNIPELRL 63 AMRYG PS+ +D LK+QGC +IL+ P YPQY+ +TTA++ D F+H K+R P +R Sbjct: 142 AMRYGQPSIASRIDALKEQGCEKILLFPLYPQYAASTTATVNDKAFEHLMKLRWQPAIRT 201 Query: 64 IRNYHDQDGYIQALRQSVLDHW-EVNGRPDKLVMSFHGVPKRTLELGDPYHCECYKTARL 122 + YHD YI+ L SV +H ++ P+ L+ SFHG+P+ + GDPY+C C KTARL Sbjct: 202 VPPYHDDPAYIEGLAASVKNHLATLDWEPEMLITSFHGIPQSYFKKGDPYYCHCQKTARL 261 Query: 123 LAQSLGLNDEQYLVTFQSRFGKAEWLQPYTAPTVQALGRQGVRRIDVMCPGFTSDCLETL 182 L ++LG ++ +++TFQSRFG EWLQPYT TV+ L +G++RI VM PGF SDCLETL Sbjct: 262 LREALGRTEKNFMITFQSRFGPEEWLQPYTDKTVEKLASEGIKRIAVMNPGFVSDCLETL 321 Query: 183 EEIAMEVKDEFLHAGGKEFHFIPCLNESPAWIAGMVEIVEQHLAGW 228 EEIA E + FLH GG++F IPCLN+S + + ++V + L GW Sbjct: 322 EEIAGEAGEIFLHNGGEKFTHIPCLNDSTEGMNVLEKVVRRELQGW 367 >NMA0927 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) NmA Neisseria meningitidis Z2491 Length = 336 Score = 243 bits (619), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 107/228 (46%), Positives = 159/228 (69%) Query: 1 VVHAMRYGSPSLPQVLDQLKQQGCTRILVLPAYPQYSGTTTASIFDAVFDHYRKVRNIPE 60 V HAM YG+PS+ VL +LK QG R+LV+P YPQY+ +++ + D V + RN Sbjct: 108 VRHAMTYGNPSVADVLSELKAQGAGRLLVIPMYPQYAASSSGAAVDKVCEQLLLQRNQMS 167 Query: 61 LRLIRNYHDQDGYIQALRQSVLDHWEVNGRPDKLVMSFHGVPKRTLELGDPYHCECYKTA 120 +R + ++D GYI A++ +L +W +GR KL++SFHGVP++ +LGDPY EC TA Sbjct: 168 VRTVSRFYDDTGYIDAMKNHILRYWAEHGRGKKLMLSFHGVPQKHYDLGDPYPDECRHTA 227 Query: 121 RLLAQSLGLNDEQYLVTFQSRFGKAEWLQPYTAPTVQALGRQGVRRIDVMCPGFTSDCLE 180 +LLA++L L ++QY+V+FQS+FG+A+W+ P T L +QGV +DV CPGF +DCLE Sbjct: 228 KLLAEALELTEDQYVVSFQSQFGRAKWVTPSTQDLFGKLPKQGVTELDVFCPGFLADCLE 287 Query: 181 TLEEIAMEVKDEFLHAGGKEFHFIPCLNESPAWIAGMVEIVEQHLAGW 228 T+EEIA+ +++F AGGK + +IPCLN++P WI +V + E++L GW Sbjct: 288 TMEEIALMGREQFYEAGGKSYRYIPCLNDNPDWIDALVALAEENLGGW 335 >VC0987 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Vch Vibrio cholerae Length = 324 Score = 242 bits (618), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 113/219 (51%), Positives = 160/219 (73%) Query: 4 AMRYGSPSLPQVLDQLKQQGCTRILVLPAYPQYSGTTTASIFDAVFDHYRKVRNIPELRL 63 M YG PSL + + +L+QQG +I+VLP YPQYS TTTA++FD + R++ +PEL Sbjct: 103 GMTYGEPSLLEGVRKLQQQGVEQIVVLPLYPQYSATTTAAVFDGLAKALRQLPVVPELHF 162 Query: 64 IRNYHDQDGYIQALRQSVLDHWEVNGRPDKLVMSFHGVPKRTLELGDPYHCECYKTARLL 123 IR+YHD YIQAL +SV W+ +G+ D L+ S+HG+PKR + GD Y C KT LL Sbjct: 163 IRDYHDHPLYIQALAKSVRASWQQHGQGDLLLCSYHGIPKRYAQNGDIYPEHCLKTTELL 222 Query: 124 AQSLGLNDEQYLVTFQSRFGKAEWLQPYTAPTVQALGRQGVRRIDVMCPGFTSDCLETLE 183 AQ+LGL ++ ++T+QS+FGK EWLQPYT T++AL RQG++++DV+CP F+ DCLETLE Sbjct: 223 AQALGLPQDKVMMTYQSQFGKEEWLQPYTDKTMEALPRQGIKKLDVICPAFSVDCLETLE 282 Query: 184 EIAMEVKDEFLHAGGKEFHFIPCLNESPAWIAGMVEIVE 222 EIA + ++ FLH+GG+ FH++PCLN+S + I M +V+ Sbjct: 283 EIAEQNQEIFLHSGGEAFHYVPCLNDSQSHIELMAALVK 321 >NMB0718 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Nme Neisseria meningitidis MC58 Length = 360 Score = 239 bits (611), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 106/228 (46%), Positives = 158/228 (69%) Query: 1 VVHAMRYGSPSLPQVLDQLKQQGCTRILVLPAYPQYSGTTTASIFDAVFDHYRKVRNIPE 60 V HAM YG+PS+ VL +LK QG R+LV+P YPQY+ +++ + D V + RN Sbjct: 132 VRHAMTYGNPSVADVLSELKAQGAGRLLVIPMYPQYAASSSGAAVDKVCEQLLLQRNQMS 191 Query: 61 LRLIRNYHDQDGYIQALRQSVLDHWEVNGRPDKLVMSFHGVPKRTLELGDPYHCECYKTA 120 +R + ++D GYI A++ +L +W +GR KL++SFHGVP++ +LGDPY EC TA Sbjct: 192 VRTVSRFYDDTGYIDAMKNHILRYWAEHGRGKKLMLSFHGVPQKHHDLGDPYPDECRHTA 251 Query: 121 RLLAQSLGLNDEQYLVTFQSRFGKAEWLQPYTAPTVQALGRQGVRRIDVMCPGFTSDCLE 180 +LLA++L L ++QY+V+FQS+FG+A+W+ P T L +QGV +DV CPGF +DCLE Sbjct: 252 KLLAEALELTEDQYVVSFQSQFGRAKWVTPSTQDLFGKLPKQGVTELDVFCPGFLADCLE 311 Query: 181 TLEEIAMEVKDEFLHAGGKEFHFIPCLNESPAWIAGMVEIVEQHLAGW 228 T+EEIA+ +++F AGGK + +IPCLN++P WI +V + E++L W Sbjct: 312 TMEEIALMGREQFYEAGGKSYRYIPCLNDNPDWIDALVALAEENLGSW 359