BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0106.p (448 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value yjiZ [GEPR] COG0477 Permeases of the major facilitator superfami... 327 3e-89 ECs5316 [GEPR] COG0477 Permeases of the major facilitator superf... 325 2e-88 ZyjiZ [GEPR] COG0477 Permeases of the major facilitator superfam... 325 2e-88 yhaU [GEPR] COG0477 Permeases of the major facilitator superfami... 183 6e-46 ZyhaU [GEPR] COG0477 Permeases of the major facilitator superfam... 183 6e-46 >yjiZ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 453 Score = 327 bits (838), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 161/325 (49%), Positives = 223/325 (68%), Gaps = 8/325 (2%) Query: 6 EKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFSLAY 65 ++S R+KRIQ A+ L A ++NYLDRS+LS+AN ++ +EL LSA+++G LLS FSLAY Sbjct: 31 QRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAY 90 Query: 66 AFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVNNLQQFLVARVFLGLGEAPQFPA 125 +QLP G +LD+ G R+MLG GMF WS+ Q G V+N QF++ R+ +G+GEAP P Sbjct: 91 GIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPC 150 Query: 126 GAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFVIMGVLGIAVS 185 G KV+++WF ++ERG P G F A+STIG A++PPIL +ML GWR MF+ +GVLGI ++ Sbjct: 151 GVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLA 210 Query: 186 VGWYLFYRNRNEVQLTPSEVLYLADDHDNDPNANAK---LSWSEWKSLFTYRTTWGMLFG 242 +GWY+ YRNR V+LT E YL N + NA+ LS++EW+SLF RT WGM+ G Sbjct: 211 IGWYMLYRNREHVELTAVEQAYL-----NAGSVNARRDPLSFAEWRSLFRNRTMWGMMLG 265 Query: 243 FMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGTLGMLSSGYIADGLMKRGM 302 F G+ Y WLYL WLP YL+ +L + TG + IP++FG GML +GY+ D L+K GM Sbjct: 266 FSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGM 325 Query: 303 PAIRSRKWPICAGLIGASDXSRKWP 327 I+SRK I AG+ ++ + P Sbjct: 326 APIKSRKICIIAGMFCSAAFTLIVP 350 >ECs5316 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 453 Score = 325 bits (832), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 160/325 (49%), Positives = 223/325 (68%), Gaps = 8/325 (2%) Query: 6 EKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFSLAY 65 ++S R+KRIQ A+ L A ++NYLDRS+LS+AN ++ +EL LSA+++G LLS FSLAY Sbjct: 31 QRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAY 90 Query: 66 AFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVNNLQQFLVARVFLGLGEAPQFPA 125 +QLP G +LD+ G R+MLG GMF WS+ Q G V++ QF++ R+ +G+GEAP P Sbjct: 91 GIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPC 150 Query: 126 GAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFVIMGVLGIAVS 185 G KV+++WF ++ERG P G F A+STIG A++PPIL +ML GWR MF+ +GVLGI ++ Sbjct: 151 GVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLA 210 Query: 186 VGWYLFYRNRNEVQLTPSEVLYLADDHDNDPNANAK---LSWSEWKSLFTYRTTWGMLFG 242 +GWY+ YRNR V+LT E YL N + NA+ LS++EW+SLF RT WGM+ G Sbjct: 211 IGWYMLYRNREHVELTAVEQAYL-----NAGSVNARRDPLSFAEWRSLFRNRTMWGMMLG 265 Query: 243 FMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGTLGMLSSGYIADGLMKRGM 302 F G+ Y WLYL WLP YL+ +L + TG + IP++FG GML +GY+ D L+K GM Sbjct: 266 FSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGM 325 Query: 303 PAIRSRKWPICAGLIGASDXSRKWP 327 I+SRK I AG+ ++ + P Sbjct: 326 APIKSRKICIIAGMFCSAAFTLIVP 350 >ZyjiZ [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 453 Score = 325 bits (832), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 160/325 (49%), Positives = 223/325 (68%), Gaps = 8/325 (2%) Query: 6 EKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFSLAY 65 ++S R+KRIQ A+ L A ++NYLDRS+LS+AN ++ +EL LSA+++G LLS FSLAY Sbjct: 31 QRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAY 90 Query: 66 AFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVNNLQQFLVARVFLGLGEAPQFPA 125 +QLP G +LD+ G R+MLG GMF WS+ Q G V++ QF++ R+ +G+GEAP P Sbjct: 91 GIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPC 150 Query: 126 GAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFVIMGVLGIAVS 185 G KV+++WF ++ERG P G F A+STIG A++PPIL +ML GWR MF+ +GVLGI ++ Sbjct: 151 GVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLA 210 Query: 186 VGWYLFYRNRNEVQLTPSEVLYLADDHDNDPNANAK---LSWSEWKSLFTYRTTWGMLFG 242 +GWY+ YRNR V+LT E YL N + NA+ LS++EW+SLF RT WGM+ G Sbjct: 211 IGWYMLYRNREHVELTAVEQAYL-----NAGSVNARRDPLSFAEWRSLFRNRTMWGMMLG 265 Query: 243 FMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGTLGMLSSGYIADGLMKRGM 302 F G+ Y WLYL WLP YL+ +L + TG + IP++FG GML +GY+ D L+K GM Sbjct: 266 FSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGM 325 Query: 303 PAIRSRKWPICAGLIGASDXSRKWP 327 I+SRK I AG+ ++ + P Sbjct: 326 APIKSRKICIIAGMFCSAAFTLIVP 350 >yhaU [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 444 Score = 183 bits (465), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 117/337 (34%), Positives = 181/337 (53%), Gaps = 23/337 (6%) Query: 2 EVQKEKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAF 61 V ++K R ++ + F++ A VNY DR+TLSIA V++EL LSA MG + SAF Sbjct: 5 TVDEKKKGVHTRYLILLIIFIVTA--VNYADRATLSIAGTEVAKELQLSAVSMGYIFSAF 62 Query: 62 SLAYAFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVN-------NLQQFLVARVF 114 AY Q+P G +LDKFG++ + +F WS+ GFV+ + F + R Sbjct: 63 GWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFM-RFM 121 Query: 115 LGLGEAPQFPAGAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMF 174 LG EAP FPA A++V+ WF +ERG + IF ++ AL P+L L ++GW +F Sbjct: 122 LGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVF 181 Query: 175 VIMGVLGIAVSVGWY-LFYRNRNEVQLTPSEVLYLAD-------DHDNDPNANA---KLS 223 +MGV+G ++ W L + + +++ E+ ++++ DH +A A KL Sbjct: 182 TVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLH 241 Query: 224 WSEWKSLFTYRTTWGMLFGFMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFG 283 + K L + R G+ FG + + W +LTW P YL E+ +SI + G V IP + G Sbjct: 242 YI--KQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCG 299 Query: 284 TLGMLSSGYIADGLMKRGMPAIRSRKWPICAGLIGAS 320 G + G +D L+KRG+ +RK PI G++ AS Sbjct: 300 FAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLAS 336 >ZyhaU [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 444 Score = 183 bits (465), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 117/337 (34%), Positives = 181/337 (53%), Gaps = 23/337 (6%) Query: 2 EVQKEKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAF 61 V ++K R ++ + F++ A VNY DR+TLSIA V++EL LSA MG + SAF Sbjct: 5 TVDEKKKGVHTRYLILLIIFIVTA--VNYADRATLSIAGTEVAKELQLSAVSMGYIFSAF 62 Query: 62 SLAYAFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVN-------NLQQFLVARVF 114 AY Q+P G +LDKFG++ + +F WS+ GFV+ + F + R Sbjct: 63 GWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFM-RFM 121 Query: 115 LGLGEAPQFPAGAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMF 174 LG EAP FPA A++V+ WF +ERG + IF ++ AL P+L L ++GW +F Sbjct: 122 LGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVF 181 Query: 175 VIMGVLGIAVSVGWY-LFYRNRNEVQLTPSEVLYLAD-------DHDNDPNANA---KLS 223 +MGV+G ++ W L + + +++ E+ ++++ DH +A A KL Sbjct: 182 TVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLH 241 Query: 224 WSEWKSLFTYRTTWGMLFGFMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFG 283 + K L + R G+ FG + + W +LTW P YL E+ +SI + G V IP + G Sbjct: 242 YI--KQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCG 299 Query: 284 TLGMLSSGYIADGLMKRGMPAIRSRKWPICAGLIGAS 320 G + G +D L+KRG+ +RK PI G++ AS Sbjct: 300 FAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLAS 336