BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0010.0024.p (304 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ZyeaT [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 333 2e-91 ECs2508 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 333 2e-91 yeaT [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 323 2e-88 YPO2497 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 311 2e-84 STM0333 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 261 1e-69 >ZyeaT [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 314 Score = 333 bits (855), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 154/295 (52%), Positives = 218/295 (73%) Query: 1 VNNTPLLEDLRLFCVVARHSSFAGSAREVGASPAYISKRIALLEQALGVRLFHRTTRSVV 60 +NN PLL DLR+F +VAR + FA A E+G SPA++SKRIALLEQ L V L HRTTR V Sbjct: 8 MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLEQTLNVVLLHRTTRRVT 67 Query: 61 MTEEGGNVHEWARRILDDVEQMMETVSSAKRVPRGLLKISTSFGLGRKVVSPLLSRFASE 120 +TEEG ++EWA+RIL DV QMM+ +S ++VP+G+L+I +SFG GR+VV+P LS A Sbjct: 68 ITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISSFGFGRQVVAPALSALAKA 127 Query: 121 HPELKIQLELVDRQIDLVNEGIDLDIRVGAGHEPHLFSKRILPSQRVLCASPAYLKKHGL 180 +P+L+++ ++ DR +DLVNEG+DLDIR+G P+L ++++ + R+LCASP ++ +HG Sbjct: 128 YPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARKLATNYRILCASPEFIAQHGA 187 Query: 181 PADLAALRQHQCLVIRERNQSFGIWRMMGPKGVETVKVSGMLASNHGEIIHQWAVDGHGI 240 P L L CLVI+ER+ FG+W++ +G +KV+G L+SNHGEI+HQW +DG GI Sbjct: 188 PKHLTDLSALPCLVIKERDHPFGVWQLRNKEGHHAIKVTGPLSSNHGEIVHQWCLDGQGI 247 Query: 241 ILRSAWDVADSLKRGRLVRVLPQYYQEADLCAVYPLQLKNSAKVRECVRFLQKHL 295 LRS WDV++++ G LV+VLP+YYQ A++ AVY +L SAKVR V FL+++ Sbjct: 248 ALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVSRLATSAKVRITVEFLRQYF 302 >ECs2508 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 314 Score = 333 bits (855), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 154/295 (52%), Positives = 218/295 (73%) Query: 1 VNNTPLLEDLRLFCVVARHSSFAGSAREVGASPAYISKRIALLEQALGVRLFHRTTRSVV 60 +NN PLL DLR+F +VAR + FA A E+G SPA++SKRIALLEQ L V L HRTTR V Sbjct: 8 MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLEQTLNVVLLHRTTRRVT 67 Query: 61 MTEEGGNVHEWARRILDDVEQMMETVSSAKRVPRGLLKISTSFGLGRKVVSPLLSRFASE 120 +TEEG ++EWA+RIL DV QMM+ +S ++VP+G+L+I +SFG GR+VV+P LS A Sbjct: 68 ITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISSFGFGRQVVAPALSALAKA 127 Query: 121 HPELKIQLELVDRQIDLVNEGIDLDIRVGAGHEPHLFSKRILPSQRVLCASPAYLKKHGL 180 +P+L+++ ++ DR +DLVNEG+DLDIR+G P+L ++++ + R+LCASP ++ +HG Sbjct: 128 YPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARKLATNYRILCASPEFIAQHGA 187 Query: 181 PADLAALRQHQCLVIRERNQSFGIWRMMGPKGVETVKVSGMLASNHGEIIHQWAVDGHGI 240 P L L CLVI+ER+ FG+W++ +G +KV+G L+SNHGEI+HQW +DG GI Sbjct: 188 PKHLTDLSALPCLVIKERDHPFGVWQLRNKEGHHAIKVTGPLSSNHGEIVHQWCLDGQGI 247 Query: 241 ILRSAWDVADSLKRGRLVRVLPQYYQEADLCAVYPLQLKNSAKVRECVRFLQKHL 295 LRS WDV++++ G LV+VLP+YYQ A++ AVY +L SAKVR V FL+++ Sbjct: 248 ALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVSRLATSAKVRITVEFLRQYF 302 >yeaT [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 314 Score = 323 bits (829), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 153/295 (51%), Positives = 217/295 (73%) Query: 1 VNNTPLLEDLRLFCVVARHSSFAGSAREVGASPAYISKRIALLEQALGVRLFHRTTRSVV 60 +NN PLL DLR+F +VAR + FA A E+G SPA++SKRIALLEQ L V L HRTTR V Sbjct: 8 MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLEQTLNVVLLHRTTRRVT 67 Query: 61 MTEEGGNVHEWARRILDDVEQMMETVSSAKRVPRGLLKISTSFGLGRKVVSPLLSRFASE 120 +TEEG ++EWA+RIL DV QMM+ +S ++VP+G+L+I +SFG GR+VV+P L A Sbjct: 68 ITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISSFGFGRQVVAPALLALAKA 127 Query: 121 HPELKIQLELVDRQIDLVNEGIDLDIRVGAGHEPHLFSKRILPSQRVLCASPAYLKKHGL 180 +P+L+++ ++ DR +DLVNEG+DLDIR+G P+L ++++ + R+LCASP ++ +HG Sbjct: 128 YPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARKLATNYRILCASPEFIAQHGA 187 Query: 181 PADLAALRQHQCLVIRERNQSFGIWRMMGPKGVETVKVSGMLASNHGEIIHQWAVDGHGI 240 P L L CLVI+ER+ FG+W++ +G +KV+G L+SNHGEI+HQW +DG GI Sbjct: 188 PKHLTDLSALPCLVIKERDHPFGVWQLRNKEGPHAIKVTGPLSSNHGEIVHQWCLDGQGI 247 Query: 241 ILRSAWDVADSLKRGRLVRVLPQYYQEADLCAVYPLQLKNSAKVRECVRFLQKHL 295 LRS WDV++++ G LV+VLP+YYQ A++ AVY +L SAKVR V FL+++ Sbjct: 248 ALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVSRLATSAKVRITVEFLRQYF 302 >YPO2497 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 313 Score = 311 bits (796), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 148/296 (50%), Positives = 218/296 (73%) Query: 1 VNNTPLLEDLRLFCVVARHSSFAGSAREVGASPAYISKRIALLEQALGVRLFHRTTRSVV 60 +NN P+L DLR+F +VAR + FA +A E+G SPAY+SKR+A+LE+ L V L HRTTR V Sbjct: 1 MNNLPILSDLRVFLLVARRAGFAAAAEEMGVSPAYVSKRVAILEKTLNVALLHRTTRRVT 60 Query: 61 MTEEGGNVHEWARRILDDVEQMMETVSSAKRVPRGLLKISTSFGLGRKVVSPLLSRFASE 120 ++E+G +EWA+RIL DV+QMM+ +S+ ++ P+G L++ +SFG GR+ V+P LS A E Sbjct: 61 ISEDGERTYEWAQRILHDVDQMMDELSAIRQEPQGTLRVISSFGFGRRFVAPALSALARE 120 Query: 121 HPELKIQLELVDRQIDLVNEGIDLDIRVGAGHEPHLFSKRILPSQRVLCASPAYLKKHGL 180 +P L+++ ++ DR IDLV EG+DLDIRVG +L + ++ P++R+LCASP +L+++G Sbjct: 121 YPRLELRFDVEDRLIDLVTEGVDLDIRVGDNIGDNLIACQLAPNRRILCASPDFLQRYGT 180 Query: 181 PADLAALRQHQCLVIRERNQSFGIWRMMGPKGVETVKVSGMLASNHGEIIHQWAVDGHGI 240 P L+ L CLVI+ER+ FGIWR+ +++KV+G +ASNHGEI+HQW +DG GI Sbjct: 181 PKALSELPGFACLVIKERDHPFGIWRLHNGTEEQSIKVTGPMASNHGEIVHQWCLDGQGI 240 Query: 241 ILRSAWDVADSLKRGRLVRVLPQYYQEADLCAVYPLQLKNSAKVRECVRFLQKHLD 296 LRS WDV D++ G+LV +LP+Y+Q A++ AVY +L SAKVR V FL+++ + Sbjct: 241 ALRSYWDVKDNIHSGKLVHILPEYFQSANIWAVYVTRLAMSAKVRVSVEFLRRYFN 296 >STM0333 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 321 Score = 261 bits (668), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 126/291 (43%), Positives = 193/291 (66%) Query: 5 PLLEDLRLFCVVARHSSFAGSAREVGASPAYISKRIALLEQALGVRLFHRTTRSVVMTEE 64 P +EDL +F VAR+ FA +A E+G SP+YISKRIA+LE+ L RLF R R + +T E Sbjct: 18 PSVEDLFVFVTVARNGGFARAALELGLSPSYISKRIAILEKCLNARLFFRNNRVMRLTPE 77 Query: 65 GGNVHEWARRILDDVEQMMETVSSAKRVPRGLLKISTSFGLGRKVVSPLLSRFASEHPEL 124 G N A +++ +++ + + + + V G + I+ SFG G K V+ LS F +P++ Sbjct: 78 GENALGGAMQVVSEMDGFVSRLDNQRGVLAGNITINCSFGFGHKYVAEALSSFMIAYPDI 137 Query: 125 KIQLELVDRQIDLVNEGIDLDIRVGAGHEPHLFSKRILPSQRVLCASPAYLKKHGLPADL 184 ++L L DR++DLV EGID++IRVG ++++ ++R+LCASP YL++HG P + Sbjct: 138 TVKLTLTDREVDLVEEGIDIEIRVGDDINELYIARQLATNRRILCASPEYLERHGKPESV 197 Query: 185 AALRQHQCLVIRERNQSFGIWRMMGPKGVETVKVSGMLASNHGEIIHQWAVDGHGIILRS 244 +AL QH CL+I+E+N +FG W + K +++G +SN G ++ WA+ GHGI LRS Sbjct: 198 SALVQHDCLMIQEKNSAFGNWILTDGKQQTHCRLNGFHSSNSGSVVLIWALKGHGITLRS 257 Query: 245 AWDVADSLKRGRLVRVLPQYYQEADLCAVYPLQLKNSAKVRECVRFLQKHL 295 WDVA ++RG LVRVLPQ+YQEA++ AVY + +S +++ C+ FL +HL Sbjct: 258 EWDVAQYIERGELVRVLPQWYQEANIWAVYTRRSSSSDRIKICIDFLTEHL 308