BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0010.0021.p (548 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1047 [GEPR] COG0477 Permeases of the major facilitator superf... 737 0.0 AGl343 [GEPR] COG0477 Permeases of the major facilitator superfa... 641 0.0 NMA1574 [GEPR] COG0477 Permeases of the major facilitator superf... 490 e-138 NMB1362 [GEPR] COG0477 Permeases of the major facilitator superf... 486 e-137 BH2528 [GEPR] COG0477 Permeases of the major facilitator superfa... 273 1e-72 >RSp1047 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 549 Score = 737 bits (1903), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/543 (69%), Positives = 447/543 (82%), Gaps = 3/543 (0%) Query: 5 FLNKEHTVAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGADVGF 64 F ++E TVA GFNRWLVPPAALAIHLCIGMAYGFSVFWLPLS+ALG+T CGADV Sbjct: 9 FFSRERTVAAVGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRALGITQSHTCGADVSL 68 Query: 65 FAQVFSSSCDWKISMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCGGLLI 124 A++F++SCDW+IS LGWMYT+FFV LG SAALWGGWLE GPRKAGVV+A+CWCGGLLI Sbjct: 69 IAELFTTSCDWRISSLGWMYTLFFVFLGASAALWGGWLERVGPRKAGVVSAVCWCGGLLI 128 Query: 125 SALGVKTHQIWLMWLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAL 184 SA GV+THQ+W++W+GSGVIGG+GLGLGYISPVSTLIKWFPD+RGMATGMAIMGFGGGA+ Sbjct: 129 SAFGVQTHQLWMLWIGSGVIGGIGLGLGYISPVSTLIKWFPDKRGMATGMAIMGFGGGAM 188 Query: 185 VGTPLADALMKKFATPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWTPPVA 244 +G PLAD LMK FA+ SVGV +TF+V+A IYFVFMMAGA GYRVPP GWKPAGW P A Sbjct: 189 IGAPLADRLMKLFASADSVGVSQTFIVLAAIYFVFMMAGALGYRVPPAGWKPAGWKPSPA 248 Query: 245 KSSATMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKLLGVN 304 K++ TM+TQ HVHVS+ PQFWL+W VLCLNVSAGIGV+G+ASP+LQEVFGGKLLGV Sbjct: 249 KANDTMVTQRHVHVSQAVKTPQFWLIWAVLCLNVSAGIGVLGMASPLLQEVFGGKLLGVT 308 Query: 305 IGFNDLSVEQKTAIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLGFVLY 364 F +L+ QK IAA+AAGFTGL+SLFNIGGRF WAS SD GRK+TYA+FF LGFVLY Sbjct: 309 TAFTELTAAQKGQIAAIAAGFTGLLSLFNIGGRFFWASLSDRLGRKLTYAVFFALGFVLY 368 Query: 365 VSLPWSAKAGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWATA 424 ++PW++ NI LF A C+ILSMYGGGFATVPAYLAD+FGTQMVGAIHGRLLTAW+TA Sbjct: 369 AAIPWTSHTSNIALFSLAFCVILSMYGGGFATVPAYLADMFGTQMVGAIHGRLLTAWSTA 428 Query: 425 GILGPVVVNYMREYQLAQGMPKNEVYNTTMYILAGMLILGLICNLLIRPVAAKHFMTPEE 484 GILGPV+VNY+REYQ+A G+ + VY+ TM +LAG+L+LG ICNLL+RPV KHFMT + Sbjct: 429 GILGPVLVNYLREYQIAHGVARAAVYDITMMVLAGLLVLGFICNLLVRPVDPKHFMTEAQ 488 Query: 485 LAHEKKLAHEKSAADAAVTAGSGDMSQIGSGGNPVFIGLAWAAVGIPLIWGITLVLQKSA 544 L ++ H +AA A + G+ V + LAWAAVG+PL WG+ + LQK+A Sbjct: 489 LDEQR---HAATAATPQANAPETSLEWQAHPGSAVAVVLAWAAVGLPLGWGVWITLQKAA 545 Query: 545 VLF 547 VLF Sbjct: 546 VLF 548 >AGl343 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 552 Score = 641 bits (1654), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/545 (65%), Positives = 421/545 (77%), Gaps = 13/545 (2%) Query: 5 FLNKEHTVAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGADVGF 64 FL++E +A+PGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKAL T P +C + + Sbjct: 18 FLDRERIIARPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALPATDP-SC-SSLTL 75 Query: 65 FAQVFSSSCDWKISMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCGGLLI 124 +F++ C+W+++ LGW+YT+FFVLLG SAA+WGGWLE GPRKAG V+A CWCGG+L+ Sbjct: 76 MGALFTTECNWRVADLGWIYTLFFVLLGCSAAIWGGWLERVGPRKAGFVSACCWCGGILV 135 Query: 125 SALGVKTHQIWLMWLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAL 184 +A+GV THQ+WLMWLG+GVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGA+ Sbjct: 136 AAIGVATHQLWLMWLGAGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAM 195 Query: 185 VGTPLADALMKKFATPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWTPPVA 244 +G PLA+ LM F T S+GVW+TFVVMA++YF FMMAGAFGYR+PP GW+P GWT P A Sbjct: 196 IGAPLANLLMNTFKTEASIGVWQTFVVMALVYFAFMMAGAFGYRIPPAGWRPEGWTAPAA 255 Query: 245 KSSATMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKLLGV- 303 KS+ MIT HVH+ PQFWL+W VLCLNVSAGIGVIG+ASPMLQE+F G L+G+ Sbjct: 256 KSA--MITTRHVHLRDAHKTPQFWLIWAVLCLNVSAGIGVIGMASPMLQEIFAGSLIGLP 313 Query: 304 NIGFNDLSVEQKTAIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLGFVL 363 +GF DL QK IAA+AAGFTGL+SLFNIGGRF WAS SD GRK TY FFVLG +L Sbjct: 314 GVGFADLDAGQKAQIAAIAAGFTGLLSLFNIGGRFFWASMSDKIGRKNTYFCFFVLGIIL 373 Query: 364 YVSLPWSAKAGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWAT 423 Y P A GN LFV A IILSMYGGGFAT+PAYLAD+FGTQ VGAIHGRLLTAWAT Sbjct: 374 YALAPTLATMGNKALFVLAFGIILSMYGGGFATIPAYLADIFGTQFVGAIHGRLLTAWAT 433 Query: 424 AGILGPVVVNYMREYQLAQGM-PKNEVYNTTMYILAGMLILGLICNLLIRPVAAKHFMTP 482 AGI GPVVVNY+RE Q+A G+ P +Y +TMYILAGML +GLI N +RP+A K FM+ Sbjct: 434 AGIAGPVVVNYIREAQIAAGVAPGPALYTSTMYILAGMLAIGLIANAFVRPLADKWFMSD 493 Query: 483 EELAHEKKLAHEKSAADAAVTAGSGDMSQIGSGGNPVFIGLAWAAVGIPLIWGITLVLQK 542 E+A + + AG IG GG LAWAAVGIPL+WG+ + ++ Sbjct: 494 AEVAALQAKTAAAN-------AGPTGSFGIGRGGLDAKAALAWAAVGIPLLWGVWVTVRS 546 Query: 543 SAVLF 547 S LF Sbjct: 547 SLALF 551 >NMA1574 [GEPR] COG0477 Permeases of the major facilitator superfamily NmA Neisseria meningitidis Z2491 Length = 513 Score = 490 bits (1261), Expect = e-138, Method: Compositional matrix adjust. Identities = 274/547 (50%), Positives = 371/547 (67%), Gaps = 39/547 (7%) Query: 4 DFLNKEHTVAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGADVG 63 FL++E ++AKPGFNRWLVPPAALA+HL IG Y +SVF PL+K +G+T Sbjct: 2 KFLDREASIAKPGFNRWLVPPAALAVHLAIGQIYAYSVFNAPLTKLIGITE--------- 52 Query: 64 FFAQVFSSSCDWKISMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCGGLL 123 S++ DWK++ +GW++++ +LG SAAL+G W+E GPRKA AA C+ G Sbjct: 53 ------SAAGDWKLTTVGWIFSIALAMLGASAALFGTWMERVGPRKAIFAAACCFSLGFF 106 Query: 124 ISALGVKTHQIWLMWLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGA 183 +SA GV+TH ++L++LG+GVIGGVGLGLGYI PVSTL+KWFPD+ GMATG+AIMGFGGGA Sbjct: 107 VSAFGVRTHNLFLLYLGNGVIGGVGLGLGYIGPVSTLMKWFPDKPGMATGLAIMGFGGGA 166 Query: 184 LVGTPLADALMKKFATPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWTPPV 243 ++ +PL+ +LM F+ TSVGV ETF V+ ++Y MM GAF RVP GWKP G+T P Sbjct: 167 MLASPLSVSLMNTFSNATSVGVAETFAVLGLLYLALMMFGAFTIRVPADGWKPEGYTAP- 225 Query: 244 AKSSATMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKLLGV 303 K+ +++ NHV+VS+ PQFWL++ VLCLNV+AGIGV+G AS M+QE+F +G Sbjct: 226 -KTQNKLVSSNHVNVSQAMKTPQFWLLFWVLCLNVTAGIGVLGQASVMIQELFSETSIG- 283 Query: 304 NIGFNDLSVEQKTAIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLGFVL 363 Q A AAGF L+SLFN+GGRF W+S SD GRK TY IFFVLG +L Sbjct: 284 ---------RQAAVGAGAAAGFVSLLSLFNMGGRFLWSSVSDKIGRKNTYTIFFVLGSLL 334 Query: 364 YVSLPWSAKAGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWAT 423 Y ++P + G+ LF+ C+I+SMYGGGFA +PAYL DLFGT VGAIHGR+L AW+T Sbjct: 335 YFAVPSIGEGGSKALFIIGFCVIISMYGGGFAAIPAYLKDLFGTYQVGAIHGRILLAWST 394 Query: 424 AGILGPVVVNYMREYQLAQGMPKNEVYNTTMYILAGMLILGLICNLLIRPVAAKHFMTPE 483 A ++GPV+VNY+R+ Q+ G+P + Y+ TMYI+AG+LI+GL+CNL ++ V KH Sbjct: 395 AAVIGPVLVNYIRQSQIDSGIPAAQAYSVTMYIMAGLLIIGLLCNLAVKSVHEKH----- 449 Query: 484 ELAHEKKL---AHEKSAADAAVTAGSGDMSQIGSGGNPVFIGLAWAAVGIPLIWGITLVL 540 HEK + AH + D + + + + SGG + + WA IPL +G+ ++ Sbjct: 450 ---HEKDIKTAAHSGNPDDETAISDAYLVGEKVSGGG-ISVWWRWALAVIPLAYGVVMIF 505 Query: 541 QKSAVLF 547 K+ LF Sbjct: 506 VKALDLF 512 >NMB1362 [GEPR] COG0477 Permeases of the major facilitator superfamily Nme Neisseria meningitidis MC58 Length = 513 Score = 486 bits (1250), Expect = e-137, Method: Compositional matrix adjust. Identities = 273/547 (49%), Positives = 369/547 (67%), Gaps = 39/547 (7%) Query: 4 DFLNKEHTVAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGADVG 63 FL++E ++AKPGFNRWLVPPAALA+HL IG Y +SVF PL+K +G+T Sbjct: 2 KFLDREASIAKPGFNRWLVPPAALAVHLAIGQIYAYSVFNAPLTKLIGITE--------- 52 Query: 64 FFAQVFSSSCDWKISMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCGGLL 123 S++ DWK++ +GW++++ +LG SAAL+G W+E GPRKA AA C+ G Sbjct: 53 ------SAAGDWKLTTVGWIFSIALAMLGASAALFGTWMERVGPRKAIFAAACCFSLGFF 106 Query: 124 ISALGVKTHQIWLMWLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGA 183 +SA GV+TH ++L++LG+GVIGGVGLGLGYI PVSTL+KWFPD+ GMATG+AIMGFGGGA Sbjct: 107 VSAFGVRTHNLFLLYLGNGVIGGVGLGLGYIGPVSTLMKWFPDKPGMATGLAIMGFGGGA 166 Query: 184 LVGTPLADALMKKFATPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWTPPV 243 ++ +PL+ +LM F+ SVGV ETF V+ ++Y MM GAF RVP GWKP G+T P Sbjct: 167 MLASPLSVSLMNTFSNAASVGVAETFAVLGLLYLALMMFGAFTIRVPADGWKPEGYTAP- 225 Query: 244 AKSSATMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKLLGV 303 K+ +++ NHV+VS+ PQFWL++ VLCLNV+AGIGV+G AS M+QE+F +G Sbjct: 226 -KTQNKLVSSNHVNVSQAMKTPQFWLLFWVLCLNVTAGIGVLGQASVMIQELFSETSIG- 283 Query: 304 NIGFNDLSVEQKTAIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLGFVL 363 Q A AAGF L+SLFN+GGRF W+S SD GRK TY IFFVLG +L Sbjct: 284 ---------RQAAVGAGAAAGFVSLLSLFNMGGRFLWSSVSDKIGRKNTYTIFFVLGSLL 334 Query: 364 YVSLPWSAKAGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWAT 423 Y ++P + G+ LF+ C+I+SMYGGGFA +PAYL DLFGT VGAIHGR+L AW+T Sbjct: 335 YFAVPSIGEGGSKALFIIGFCVIISMYGGGFAAIPAYLKDLFGTYQVGAIHGRILLAWST 394 Query: 424 AGILGPVVVNYMREYQLAQGMPKNEVYNTTMYILAGMLILGLICNLLIRPVAAKHFMTPE 483 A ++GPV+VNY+R+ Q+ G+P + Y+ TMYI+A +LI+GL+CNL ++ V KH Sbjct: 395 AAVIGPVLVNYIRQSQIDSGIPAAQAYSVTMYIMACLLIIGLLCNLAVKSVHEKH----- 449 Query: 484 ELAHEKKL---AHEKSAADAAVTAGSGDMSQIGSGGNPVFIGLAWAAVGIPLIWGITLVL 540 HEK + AH + D + + + + SGG + + WA IPL +G+ +V Sbjct: 450 ---HEKDIKTAAHSGNPDDETAISDAYLVGEKVSGGG-ISVWWRWALAVIPLAYGVVMVF 505 Query: 541 QKSAVLF 547 K+ LF Sbjct: 506 VKALDLF 512 >BH2528 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 419 Score = 273 bits (697), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 179/461 (38%), Positives = 254/461 (55%), Gaps = 70/461 (15%) Query: 18 NRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGADVGFFAQVFSSSCDWKI 77 NRWL+ AA+ IH+ IG Y +SVF PL + G W + Sbjct: 6 NRWLIALAAVGIHISIGSVYAWSVFTNPLIEQFG-----------------------WGL 42 Query: 78 SMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCGGLLISALGVKTHQIWLM 137 + +++ LG+SAA G ++E GPRK+G+VAA + G L + L V +WL+ Sbjct: 43 GEVSLTFSIAIAFLGVSAAFMGHFVEKHGPRKSGMVAASFFGLGTLGAGLAVSLESLWLL 102 Query: 138 WLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGALVGTPLADALMKKF 197 + GV+GG GLG+GYI+PVSTL+KWFPDRRG+ATG+AIMGFG +LV +P+ +A + Sbjct: 103 YFSYGVLGGFGLGVGYITPVSTLVKWFPDRRGLATGLAIMGFGFASLVFSPIMNAFI--- 159 Query: 198 ATPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWTPP------VAKSSATMI 251 TSVG+ TF ++ +Y + M A PP GW PAG+ + K + + Sbjct: 160 ---TSVGIAATFFILGGLYMIIMFTAALYLEPPPQGWVPAGFKEAKTENGRLQKQDLSQL 216 Query: 252 TQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKLLGVNIGFNDLS 311 T N +K +FW +W +L +NV+ GI ++ +ASPM QE+ Sbjct: 217 TANEAVKTK-----RFWFLWTMLFINVTCGIAILAVASPMAQEI---------------- 255 Query: 312 VEQKTAIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLGFVLYVSLPWSA 371 AA AA GL+ LFN GR WAS SD+ GR Y FF++ V +V LP Sbjct: 256 ---TGMTAATAATMVGLMGLFNGLGRIGWASISDYIGRPNVYTAFFLIQIVAFVMLP--- 309 Query: 372 KAGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWATAGILGPVV 431 ++ LF + I++ YGGGFA++PAY+ DLFGT+ +GAIHG +LTAWA AG++GP++ Sbjct: 310 SITHVLLFQVVLFFIMTCYGGGFASIPAYIGDLFGTKQLGAIHGYILTAWALAGLVGPMI 369 Query: 432 VNYMREYQLAQGMPKNEVYNTTMYILAGMLILGLICNLLIR 472 +Y+RE Y T+YI GM I+ L +L IR Sbjct: 370 ASYIRE--------TTNSYAGTLYIFTGMFIVALAVSLFIR 402