BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0589.p (758 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3339_1 [R] COG1752 Predicted esterase of the alpha-beta hydrol... 216 1e-55 VC0603_1 [R] COG1752 Predicted esterase of the alpha-beta hydrol... 205 4e-52 BS_ylbK [R] COG1752 Predicted esterase of the alpha-beta hydrola... 152 4e-36 FN1704_1 [R] COG1752 Predicted esterase of the alpha-beta hydrol... 149 2e-35 BH2587 [R] COG1752 Predicted esterase of the alpha-beta hydrolas... 131 6e-30 >PA3339_1 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Pae Pseudomonas aeruginosa Length = 308 Score = 216 bits (551), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 130/288 (45%), Positives = 179/288 (62%), Gaps = 3/288 (1%) Query: 41 RPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIGGLYASGLDAGELERR 100 RP++ LVLSGG ARG AH+GVL+ L++ I ID IAGTSMGA++GGLYASG ELER Sbjct: 22 RPKIGLVLSGGAARGLAHIGVLKALDEQGIQIDAIAGTSMGAVVGGLYASGYTPAELERI 81 Query: 101 LAATNLSDIAFDRNERSRLPQAQREDEFQYPIS--ISAGLDGSKLKLASGLVQGNKLLAL 158 + D R +P +++D+ + + IS DG+ L L G++QG L + Sbjct: 82 ALEMDWQQALSDAPPRKDVPFRRKQDDRDFLVKQKISFRDDGT-LGLPLGVIQGQNLAMV 140 Query: 159 LQNWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLFAPFRI 218 L++ N DF +L IPFRAV+TD++ G +VV G LP+A+RASM++P +FAP I Sbjct: 141 LESLLVHTSDNRDFDKLAIPFRAVSTDIATGEKVVFRKGHLPQAIRASMSIPAVFAPVEI 200 Query: 219 DQRTLVDGGLVSNLPVQTARDMGADVVIAVNIATPLQDAAQLQSPTAVAQQMVGILIQQN 278 D R LVDGG+V N+PV ARDMG DVVI V+I PL+D L + V Q + ++ ++N Sbjct: 201 DGRLLVDGGMVDNIPVDVARDMGVDVVIVVDIGNPLRDRKDLSTVLDVMNQSITLMTRKN 260 Query: 279 VKAQKALLGAQDILIEPQMEGMSFTDFARGKDGVNAGWEAAQRQQARL 326 +AQ A L D+LI+P + G TDF R ++AG+ A ARL Sbjct: 261 SEAQLATLKPGDVLIQPPLSGYGTTDFGRVPQLIDAGYRATTVLAARL 308 >VC0603_1 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Vch Vibrio cholerae Length = 310 Score = 205 bits (521), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 118/286 (41%), Positives = 178/286 (62%) Query: 34 APAATQPRPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIGGLYASGLD 93 A A RP++ LVL+GGGA+G AH+GVL+ LE++H+P+D I GTSMGA +GGLYA+G+ Sbjct: 25 AQAQVAKRPKIALVLAGGGAKGAAHMGVLRALEEMHVPVDIITGTSMGAYVGGLYATGMS 84 Query: 94 AGELERRLAATNLSDIAFDRNERSRLPQAQREDEFQYPISISAGLDGSKLKLASGLVQGN 153 A E+E + + + + DR +RS+ +E E +Y I+ GL +++ G+VQG Sbjct: 85 AEEIEALIYSVDWNRGYRDRVDRSQRRVRDKEYEDRYQITTDLGLHWGEVRAPKGVVQGQ 144 Query: 154 KLLALLQNWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLF 213 +L +L+ T LPA F +L IP+RAVATD+ EVVLD G L AM ASM+VPG Sbjct: 145 NMLRMLRETTGNLPAFDSFDQLVIPYRAVATDIIHLQEVVLDKGFLVDAMMASMSVPGAL 204 Query: 214 APFRIDQRTLVDGGLVSNLPVQTARDMGADVVIAVNIATPLQDAAQLQSPTAVAQQMVGI 273 P+ ID LVDGG+ +N+PV+ AR MGAD++IAV+I+T + + VA Q+ Sbjct: 205 PPYEIDGLWLVDGGVTNNMPVEVARAMGADIIIAVDISTDYKSQEDFTNLFTVADQLSNY 264 Query: 274 LIQQNVKAQKALLGAQDILIEPQMEGMSFTDFARGKDGVNAGWEAA 319 L++++ + Q L ++D+L+ P + M +F + G++ A Sbjct: 265 LVRRSTERQSDHLTSRDLLLRPPVGKMETMEFDKMPAAFAMGYQEA 310 >BS_ylbK [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Bsu Bacillus subtilis Length = 260 Score = 152 bits (383), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 97/286 (33%), Positives = 150/286 (52%), Gaps = 38/286 (13%) Query: 41 RPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIGGLYASGLDAGELERR 100 +P++ L L GGARG AHLGVL L + I +D IAG+SMGAL+G YA+G D +++ Sbjct: 3 KPKIGLALGSGGARGLAHLGVLSSLHKHQIEVDMIAGSSMGALVGSFYAAGHDVATMKKV 62 Query: 101 LAATNLSDIAFDRNERSRLPQAQREDEFQYPISISAGLDGSKLKLASGLVQGNKLLALLQ 160 A F R + ++ P KL G ++G+++ L+ Sbjct: 63 AKA-------FKRRLYA---------DYTVP------------KL--GFLKGDRVRQLVH 92 Query: 161 NWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLFAPFRIDQ 220 +T P L IP VA DL G ++V GS+ A+RAS+++PG+F P R+D Sbjct: 93 AYTFGKP----IEELQIPLGIVACDLQTGEKIVFRKGSVSDAVRASISIPGIFIPQRLDG 148 Query: 221 RTLVDGGLVSNLPVQTARDMGADVVIAVNIATPLQDAAQLQSPTAVAQQMVGILIQQNVK 280 R LVDG +V +PV +DMGAD++IA +++ + + + Q M IL + V+ Sbjct: 149 RLLVDGAVVDRIPVSVVKDMGADIIIASDVSRVRKTETAVHIFDVIMQSM-DILQNELVR 207 Query: 281 AQKALLGAQDILIEPQMEGMSFTDFARGKDGVNAGWEAAQRQQARL 326 Q A DI+I P +E S + FA ++ ++AG EA R +++ Sbjct: 208 HQTI---AADIMIRPSLETYSSSSFANIEEMISAGEEATNRMISKI 250 >FN1704_1 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Fnu Fusobacterium nucleatum Length = 375 Score = 149 bits (377), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 97/294 (32%), Positives = 154/294 (52%), Gaps = 11/294 (3%) Query: 36 AATQPRPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIGGLYASGLDAG 95 A +V LVLSGGG +GYAHLGVL+ LE+ +I ID I GTS+GA IG LY+ G Sbjct: 55 AKDNKNLKVALVLSGGGVKGYAHLGVLRVLERENIKIDYITGTSIGAFIGTLYSIGYTVD 114 Query: 96 ELERRLAATNLSDIAFDRNERSRLPQAQREDEFQYPISISAGLDGS-KLKLASGLVQGNK 154 E+E+ L N+S+ + + L ++E +Y + +S D GL + Sbjct: 115 EIEKFLDDVNVSNFLETITDNTNLSLEKKESLKKYSVHLS--FDNELNFSFPKGLRGTGE 172 Query: 155 LLALLQNWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLFA 214 LL+ + +F PIP R +AT+L+ G G + + + ASM++P +F Sbjct: 173 AYLLLKGLLGKYEHMDNFDNFPIPLRIIATNLNTGETKAFSKGDVAKILIASMSIPSIFE 232 Query: 215 PFRIDQRTLVDGGLVSNLPVQTARDMGADVVIAVNIATPL--QDAAQLQSPTAVAQQMVG 272 P +ID VDG + NLPV+ A +MGAD+V+A +I P+ +D + S A + Sbjct: 233 PMKIDGEIYVDGLVSRNLPVEEAYEMGADIVVASDIGAPVVEKDDYNILSVMNQASTIQA 292 Query: 273 ILIQQNVKAQKALLGAQDILIEPQMEGMSFTDFARGKDGVNAGWEAAQRQQARL 326 I + + +KA ILI P ++ +S D ++ ++ + G AA++Q ++ Sbjct: 293 SNITK-ISREKA-----SILISPDVKNISALDSSKKEELMKLGKVAAEKQIDKI 340 >BH2587 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Bha Bacillus halodurans Length = 275 Score = 131 bits (329), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 85/243 (34%), Positives = 128/243 (52%), Gaps = 35/243 (14%) Query: 41 RPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIGGLYASGLDAGELERR 100 RP++ L L GGARGYAH+GVL+ LEQ IPID +AG+SMGAL+ LY +G L R Sbjct: 6 RPKIGLALGSGGARGYAHIGVLKVLEQEKIPIDYLAGSSMGALVASLYGAGHPTEHLIR- 64 Query: 101 LAATNLSDIAFDRNERSRLPQAQREDEFQYPISISAGLDGSKLKLASGLVQGNKLLALLQ 160 NL F R +F P G + G+++ L++ Sbjct: 65 --FANL----FKRKYYL---------DFTVP--------------KMGFIAGHRVEELIR 95 Query: 161 NWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLFAPFRIDQ 220 L L P R VA DL G V+L G + A+RAS+A+PG+F P I+ Sbjct: 96 ----VLAKKKRVEELDPPVRIVAADLLKGERVILQEGDVAEAVRASIAIPGIFVPKNIND 151 Query: 221 RTLVDGGLVSNLPVQTARDMGADVVIAVNIATPLQDAAQLQSPTAVAQQMVGILIQQNVK 280 R L+DGG++ +PV ++MGAD+ IAV++ T ++ +++S V Q + ++ ++ V+ Sbjct: 152 RLLIDGGVIDRVPVSVVKEMGADLTIAVDL-TIFREELEIRSVYDVILQTMDMMSKELVR 210 Query: 281 AQK 283 Q+ Sbjct: 211 VQE 213