BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0586.p (208 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl2702 [F] COG0027 Formate-dependent phosphoribosylglycinamide ... 254 1e-67 MJ1486 [F] COG0027 Formate-dependent phosphoribosylglycinamide f... 237 1e-62 PA3751 [F] COG0027 Formate-dependent phosphoribosylglycinamide f... 224 1e-58 BS_purT [F] COG0027 Formate-dependent phosphoribosylglycinamide ... 219 3e-57 VC1228 [F] COG0027 Formate-dependent phosphoribosylglycinamide f... 219 4e-57 >Cgl2702 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Cgl Corynebacterium glutamicum Length = 408 Score = 254 bits (649), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 124/204 (60%), Positives = 157/204 (76%), Gaps = 1/204 (0%) Query: 1 VIVEGFIDFDYEITLLTVRSLN-ENGDTITSFCDPIGHVQVKGDYVESWQPHPMPGAALE 59 VIVE F++FDYEITLLTVRS++ T FC+PIGH Q GDYVESWQP M ALE Sbjct: 196 VIVEAFVEFDYEITLLTVRSIDPTTSKPATWFCEPIGHRQEDGDYVESWQPMEMTPRALE 255 Query: 60 KARDIARKVTENLGGLGLFGVELFVKGDMVWFSEVSPRPHDTGMVTMVSQVQSEFQLHAK 119 AR +A ++T LGG G+FGVELFV GD V+FSEVSPRPHDTG+VT+ +Q SEF+LHAK Sbjct: 256 NARSVAARITNALGGRGVFGVELFVSGDDVYFSEVSPRPHDTGLVTLATQRFSEFELHAK 315 Query: 120 AILGLPVNTALRTPGASAVIYGQHEARGIAFDGVAEALRIPGAEIRLFGKPESFARRRMG 179 AILGLPV+ L +PGASAVIYG E+ G+++ G+AEAL + ++R+F KPE+F +RRMG Sbjct: 316 AILGLPVDVTLISPGASAVIYGGIESEGVSYTGLAEALAVAETDLRIFAKPEAFTKRRMG 375 Query: 180 VALASADNVETARIRAKQAAAKVK 203 VA+++A++V AR RA AAA +K Sbjct: 376 VAVSTAEDVAAARDRATLAAAAIK 399 >MJ1486 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Mja Methanococcus jannaschii Length = 393 Score = 237 bits (605), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 120/203 (59%), Positives = 148/203 (72%), Gaps = 6/203 (2%) Query: 1 VIVEGFIDFDYEITLLTVRSLNENGDTITSFCDPIGHVQVKGDYVESWQPHPMPGAALEK 60 VIVE FI+FDYEITLLT R+ T FC+PIGHVQ+ GDY ESWQPH M E+ Sbjct: 195 VIVEEFINFDYEITLLTARTAEG-----TKFCEPIGHVQIDGDYHESWQPHNMSAELKEQ 249 Query: 61 ARDIARKVTENLGGLGLFGVELFVKGDMVWFSEVSPRPHDTGMVTMVSQVQSEFQLHAKA 120 A+DIA+KVT+ LGG G+FGVELFVKGD V FSEVSPRPHDTGMVTM++Q SEF++H +A Sbjct: 250 AQDIAKKVTDALGGYGIFGVELFVKGDEVIFSEVSPRPHDTGMVTMITQEMSEFEIHVRA 309 Query: 121 ILGLPVNTALRTPGASAVIYGQHEARGIAFDGVAEALRIPGAEIRLFGKPESFARRRMGV 180 ILGLPV+T L PGAS VI + + + +AL++P ++RLFGKP + RRMGV Sbjct: 310 ILGLPVSTKLIHPGASHVIKAEINKYAPKYH-IEDALKVPNTKLRLFGKPNAKVGRRMGV 368 Query: 181 ALASADNVETARIRAKQAAAKVK 203 ALA AD+VE AR A++ A V+ Sbjct: 369 ALAYADSVEKARELAEKCAHAVR 391 >PA3751 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Pae Pseudomonas aeruginosa Length = 393 Score = 224 bits (571), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 116/190 (61%), Positives = 139/190 (73%), Gaps = 6/190 (3%) Query: 1 VIVEGFIDFDYEITLLTVRSLNENGDTITSFCDPIGHVQVKGDYVESWQPHPMPGAALEK 60 VIVEGFIDFDYEITLLTVR ++ T+FC PIGH QVKGDY ESWQP M AL + Sbjct: 192 VIVEGFIDFDYEITLLTVRHVDG-----TTFCAPIGHRQVKGDYHESWQPQAMSAQALAE 246 Query: 61 ARDIARKVTENLGGLGLFGVELFVKGDMVWFSEVSPRPHDTGMVTMVSQVQSEFQLHAKA 120 + +AR VTE LGG GLFGVELFVKGD VWFSEVSPRPHDTG+VT++SQ SEF LHA+A Sbjct: 247 SERVARAVTEALGGRGLFGVELFVKGDQVWFSEVSPRPHDTGLVTLISQDLSEFALHARA 306 Query: 121 ILGLPVNTALRT-PGASAVIYGQHEARGIAFDGVAEALRIPGAEIRLFGKPESFARRRMG 179 ILGLP+ + P ASAVI + ++R +AF + AL +RLFGKPE +RRMG Sbjct: 307 ILGLPIPVIRQLGPSASAVILVEGKSRQVAFANLGAALSEADTALRLFGKPEVDGQRRMG 366 Query: 180 VALASADNVE 189 VALA ++++ Sbjct: 367 VALARDESID 376 >BS_purT [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Bsu Bacillus subtilis Length = 384 Score = 219 bits (558), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 110/199 (55%), Positives = 143/199 (71%), Gaps = 6/199 (3%) Query: 1 VIVEGFIDFDYEITLLTVRSLNENGDTITSFCDPIGHVQVKGDYVESWQPHPMPGAALEK 60 VIVE FI F+ EITLLTVR++N T+FC+PIGHVQ GDY+ESWQPH M +E+ Sbjct: 184 VIVEEFIPFESEITLLTVRAVNG-----TAFCEPIGHVQKDGDYIESWQPHDMTEQQIEE 238 Query: 61 ARDIARKVTENLGGLGLFGVELFVKGDMVWFSEVSPRPHDTGMVTMVSQVQSEFQLHAKA 120 A+ IA+ +T+ LGG GLFGVELF+ D V+FSEVSPRPHDTG+VT+V+Q SEF LH +A Sbjct: 239 AKHIAKTITDELGGYGLFGVELFLAKDRVYFSEVSPRPHDTGLVTLVTQNLSEFALHVRA 298 Query: 121 ILGLPVNTALR-TPGASAVIYGQHEARGIAFDGVAEALRIPGAEIRLFGKPESFARRRMG 179 ILG P+ + +PGAS + E +G+ AL +P ++R+FGKP + A RRM Sbjct: 299 ILGFPITEITQLSPGASRPLKAPEELADYTVEGLENALAVPKTQVRVFGKPITKAGRRMA 358 Query: 180 VALASADNVETARIRAKQA 198 VAL++AD+VETAR AK+A Sbjct: 359 VALSAADSVETARENAKKA 377 >VC1228 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Vch Vibrio cholerae Length = 393 Score = 219 bits (558), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 112/204 (54%), Positives = 140/204 (68%), Gaps = 6/204 (2%) Query: 1 VIVEGFIDFDYEITLLTVRSLNENGDTITSFCDPIGHVQVKGDYVESWQPHPMPGAALEK 60 VIVEGF+DFDYEITLLTVR+++ FC PIGH Q GDY ESWQP M A++ Sbjct: 192 VIVEGFVDFDYEITLLTVRAVDG-----VHFCAPIGHRQEDGDYRESWQPQVMSENAIKA 246 Query: 61 ARDIARKVTENLGGLGLFGVELFVKGDMVWFSEVSPRPHDTGMVTMVSQVQSEFQLHAKA 120 A +A +V LGG GLFGVELFVKGD V F+EVSPRPHDTGMVT++SQ SEF LH +A Sbjct: 247 AEYVAEQVVNALGGYGLFGVELFVKGDKVIFNEVSPRPHDTGMVTLISQELSEFALHVRA 306 Query: 121 ILGLPVNTALRT-PGASAVIYGQHEARGIAFDGVAEALRIPGAEIRLFGKPESFARRRMG 179 GLP+ ++ P ASA I GQ +++ I F+G+ +AL IP ++RLFGKP+ RRR+G Sbjct: 307 FTGLPIGQIVQYGPSASAAILGQGQSQNIQFNGLDDALSIPHTQVRLFGKPDIAGRRRLG 366 Query: 180 VALASADNVETARIRAKQAAAKVK 203 VAL+ + A RA + A VK Sbjct: 367 VALSRGKTTQEATDRAIECAKAVK 390