BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0577.p (553 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0547 [GEPR] COG0477 Permeases of the major facilitator superf... 767 0.0 BMEII0406 [GEPR] COG0477 Permeases of the major facilitator supe... 681 0.0 SMc04407 [GEPR] COG0477 Permeases of the major facilitator super... 680 0.0 CC0980 [GEPR] COG0477 Permeases of the major facilitator superfa... 670 0.0 mlr0338 [GEPR] COG0477 Permeases of the major facilitator superf... 666 0.0 >RSc0547 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 567 Score = 767 bits (1981), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/549 (71%), Positives = 456/549 (83%), Gaps = 9/549 (1%) Query: 13 ITPEEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAFAAGFIV 72 +T EEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFF+G DP AFIFALLAFAAGF+V Sbjct: 20 MTREEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFSGLDPTAAFIFALLAFAAGFLV 79 Query: 73 RPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGVLPNYNSIGITAPIILIILRILQG 132 RPFGALVFGRLGD++GRKYTFL+TILIMG STFIVG+LP+Y +IG AP+ILI+LR+LQG Sbjct: 80 RPFGALVFGRLGDMIGRKYTFLITILIMGTSTFIVGLLPSYTTIGAAAPVILIMLRLLQG 139 Query: 133 LALGGEYGGAATYVAEHAPEGRRGSFTAWIQTTATMGLFLSLLVILGVRTAVGEAAFADW 192 LALGGEYGGAATYVAEHAP GRRG++T+WIQTTAT+GLFLSL+VIL VR G A+F DW Sbjct: 140 LALGGEYGGAATYVAEHAPHGRRGNYTSWIQTTATLGLFLSLIVILVVRELTG-ASFEDW 198 Query: 193 GWRIPFLVSILLLAISVWIRMSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILAL 252 GWRIPFLVSI+LLA SV+IR+SM+ESPAF KMKAEGKTSKAPLTE+FGQW+NLK+VILAL Sbjct: 199 GWRIPFLVSIVLLATSVYIRLSMSESPAFQKMKAEGKTSKAPLTESFGQWRNLKIVILAL 258 Query: 253 VGLTAGQAVVWYTGQFYALFFLTQTLKVDGPTANILIAAALLLATPFFLFFGSLSDKIGR 312 VGLTAGQAVVWYTGQFYALFFLTQ LKVD TAN+LIA AL + TPFF+FFGSLSD+IGR Sbjct: 259 VGLTAGQAVVWYTGQFYALFFLTQVLKVDAFTANVLIAVALAIGTPFFVFFGSLSDRIGR 318 Query: 313 KPIILGGCLIAAVTYFPIFSGLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTK-K 371 K II+ GCL+A +TYFP+F LTH+ANPALE A Q + + + ADP C FQ +P + Sbjct: 319 KGIIMAGCLLAVLTYFPLFKALTHYANPALERAQQTAQITIKADPKECSFQGSPIAREVD 378 Query: 372 FTSSCDIVKAKLSAASVNYQNVAGAPGSVATVKIGDRIITSYDAAGLSKE---DAAAKDK 428 F SSCDI K L+ +S +Y++ G++A+V I R I S +A+ + DA +K K Sbjct: 379 FRSSCDIAKRTLAQSSASYESEDAPAGTIASVTIAGREIASLNASRTADGQNFDADSKKK 438 Query: 429 --QLSKDLADDIKAAGYPSKADPEQMNKPMVLLLLFILVIYVTMVYGPIAACLVEMFPTR 486 K ++D +KAA YPSKADP QMN MVL++L ILVIYVTMVYGPIAA LVE+FPTR Sbjct: 439 ITDFKKSVSDALKAANYPSKADPAQMNTVMVLVILVILVIYVTMVYGPIAAMLVELFPTR 498 Query: 487 IRYTSMSMPYHIGNGWFGGLLPTTSFALVAFKGDIYYGLWYPIVIAMITFVIGMLFVKET 546 IRYTSMS+PYHIGNGWFGGLLPT SFALVA G+IYYGLWYPI IA ITFVIG LFV+ET Sbjct: 499 IRYTSMSLPYHIGNGWFGGLLPTISFALVAQHGNIYYGLWYPIWIAAITFVIGALFVRET 558 Query: 547 VRNNI--HD 553 +I HD Sbjct: 559 KDVDIYRHD 567 >BMEII0406 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 632 Score = 681 bits (1757), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/612 (59%), Positives = 424/612 (69%), Gaps = 76/612 (12%) Query: 11 RGITPEEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAFAAGF 70 + +T EE+KVIFASSLGTVFEWYDFYLYG+LA+ I FF T IF LLAFAAGF Sbjct: 12 QKMTGEERKVIFASSLGTVFEWYDFYLYGTLASFIGAAFFNEYPEATRNIFVLLAFAAGF 71 Query: 71 IVRPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGVLPNYNSIGITAPIILIILRIL 130 +VRPFGALVFGR+GDLVGRKYTFLVTI+IMG STF+VG+LP S+GI APIILI LR+L Sbjct: 72 VVRPFGALVFGRIGDLVGRKYTFLVTIVIMGGSTFLVGLLPGSASLGIFAPIILIALRML 131 Query: 131 QGLALGGEYGGAATYVAEHAPEGRRGSFTAWIQTTATMGLFLSLLVILGVRTAVGEAAFA 190 QGLALGGEYGGAATYVAEHAP RRG FT+WIQTTAT+GLFLSLLVILG +T + + AFA Sbjct: 132 QGLALGGEYGGAATYVAEHAPNNRRGFFTSWIQTTATLGLFLSLLVILGAQTLLSKDAFA 191 Query: 191 DWGWRIPFLVSILLLAISVWIRMSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVIL 250 WGWRIPFLVS+LLL ISVWIRM M+ESPAF +MK EGKTSKAPL+EAFGQWKN K+ ++ Sbjct: 192 AWGWRIPFLVSVLLLGISVWIRMQMSESPAFKRMKEEGKTSKAPLSEAFGQWKNAKIALI 251 Query: 251 ALVGLTAGQAVVWYTGQFYALFFLTQTLKVDGPTANILIAAALLLATPFFLFFGSLSDKI 310 AL GLTAGQAVVWY GQFYALFFL LKV+ +ANI++A ALL+ T FF+ FG LSDKI Sbjct: 252 ALFGLTAGQAVVWYCGQFYALFFLQNVLKVENQSANIMVAIALLIGTGFFVIFGWLSDKI 311 Query: 311 GRKPIILGGCLIAAVTYFPIFSGLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTK 370 GRKPII+ G ++AAVTYFP+F LT+ ANPAL A Q V A P C FQFN TGT Sbjct: 312 GRKPIIMAGLILAAVTYFPLFKALTNAANPALAQAEQTVKATVMAAPGDCNFQFNATGTS 371 Query: 371 KFTSSCDIVKAKLSAASVNYQNVA----GAPGSVA------------------------- 401 KFT+SCD+ + L+ +SV Y+ V G P ++ Sbjct: 372 KFTTSCDVATSFLAKSSVPYETVQTAAPGTPATITIGDTTIQSYDAVQAGADAAAKQAAL 431 Query: 402 ------------------TVKIGDRIITSYDAA-------------GLSKEDAAAKD--- 427 T K+ D + ++ AA G +K +A D Sbjct: 432 AHGVNLALQQAGFPLVRDTAKVPDSKLDAFVAANPELQLNADAIRAGDAKTMVSAADLVK 491 Query: 428 -KQLSKDLADDI------------KAAGYPSKADPEQMNKPMVLLLLFILVIYVTMVYGP 474 K L++ A+ + A + ADP Q+N + + +L ILVIYVTMVYGP Sbjct: 492 QKLLTQSEAESLGVSSEQAVYSIPNAGAFKMVADPAQVNWVLTIAILTILVIYVTMVYGP 551 Query: 475 IAACLVEMFPTRIRYTSMSMPYHIGNGWFGGLLPTTSFALVAFKGDIYYGLWYPIVIAMI 534 IAA LVEMFPTRIRYT MS+PYHIGNGWFGGLLP FAL A KGDIYYGLWYPI+IA + Sbjct: 552 IAAILVEMFPTRIRYTGMSLPYHIGNGWFGGLLPAGVFALSAAKGDIYYGLWYPIIIASV 611 Query: 535 TFVIGMLFVKET 546 TFVIGMLFVKET Sbjct: 612 TFVIGMLFVKET 623 >SMc04407 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 629 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/618 (58%), Positives = 423/618 (68%), Gaps = 72/618 (11%) Query: 7 NTTARGITPEEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAF 66 T A +T EEKKVIFASSLGTVFEWYDFYLYGSLA I FF+ T IFALLAF Sbjct: 9 GTKAGPMTGEEKKVIFASSLGTVFEWYDFYLYGSLAVYIGATFFSQYPETTRNIFALLAF 68 Query: 67 AAGFIVRPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGVLPNYNSIGITAPIILII 126 AAGF+VRPFGALVFGRLGDLVGRKYTFLVTILIMG STF+VGVLP SIGI APIILI Sbjct: 69 AAGFLVRPFGALVFGRLGDLVGRKYTFLVTILIMGVSTFLVGVLPGAASIGIAAPIILIA 128 Query: 127 LRILQGLALGGEYGGAATYVAEHAPEGRRGSFTAWIQTTATMGLFLSLLVILGVRTAVGE 186 LR+LQGLALGGEYGGAATYVAEHAP GRRG FT+WIQTTAT+GLFLSL+VIL V+ +G+ Sbjct: 129 LRLLQGLALGGEYGGAATYVAEHAPHGRRGYFTSWIQTTATLGLFLSLVVILLVQYMLGK 188 Query: 187 AAFADWGWRIPFLVSILLLAISVWIRMSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLK 246 AFA+WGWRIPFL+S +LL +SVWIR+ MNESPAF KMK EGK SKAPLTEAFGQW+N K Sbjct: 189 EAFAEWGWRIPFLLSFVLLGVSVWIRLKMNESPAFKKMKEEGKGSKAPLTEAFGQWRNAK 248 Query: 247 LVILALVGLTAGQAVVWYTGQFYALFFLTQTLKVDGPTANILIAAALLLATPFFLFFGSL 306 + +LAL G GQAVVWY+GQFYALFFL LKVDG +AN+++AA+LLL T FF+FFG L Sbjct: 249 IAVLALFGAVVGQAVVWYSGQFYALFFLQSILKVDGQSANLMVAASLLLGTGFFVFFGWL 308 Query: 307 SDKIGRKPIILGGCLIAAVTYFPIFSGLTHFANPALEAALQKSPVIVTADPASCQFQFNP 366 SDKIGRKPII+ G L+A +TYFP+F LT NPAL A Q VTA P C+FQFNP Sbjct: 309 SDKIGRKPIIMAGLLLAMLTYFPLFKALTWAGNPALAEAQQSVRATVTAAPGDCKFQFNP 368 Query: 367 TGTKKFTSSCDIV------------------------------------------KAKLS 384 TGT KFT+SCDI +AK Sbjct: 369 TGTAKFTTSCDIATAFLTKNSVPYDVVTTAAAGTPATVKIGETTITSYDAIAAGDRAKAE 428 Query: 385 AASVNYQ-----NVAGAPGSVATVKIGDRIITSYDAA----GLSKEDAAAKDKQL---SK 432 A+ Q +G P K+ + + ++ AA GL A +K + K Sbjct: 429 EAAFGKQINMALQASGYPLVRGAAKVPESKLDAFVAANPELGLDAAAVRAGEKTMVPADK 488 Query: 433 DLADDI------------------KAAGYPSKADPEQMNKPMVLLLLFILVIYVTMVYGP 474 +AD + K + ADP ++N +++ +L +LVIYVTMVYGP Sbjct: 489 LVADKLLTQEEVGSATEMAVYNIDKGGAFTMVADPARVNWTVIIAVLTVLVIYVTMVYGP 548 Query: 475 IAACLVEMFPTRIRYTSMSMPYHIGNGWFGGLLPTTSFALVAFKGDIYYGLWYPIVIAMI 534 IAA LVE+FPTRIRYT MS+PYHIGNGWFGGLLP T+FA+ A KGDIYYGLWYPIV A I Sbjct: 549 IAALLVELFPTRIRYTGMSLPYHIGNGWFGGLLPATAFAMSAAKGDIYYGLWYPIVFAGI 608 Query: 535 TFVIGMLFVKETVRNNIH 552 T VIG+LF+ ET +IH Sbjct: 609 TLVIGLLFLPETKDRDIH 626 >CC0980 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 567 Score = 670 bits (1729), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/538 (64%), Positives = 419/538 (77%) Query: 16 EEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAFAAGFIVRPF 75 + V+ ASSLGTVFEWYDFYLYGSLA II FF+G + T FI ALLAFAAGF +RP Sbjct: 30 RDTMVVGASSLGTVFEWYDFYLYGSLAPIITSHFFSGVNETTGFILALLAFAAGFAIRPL 89 Query: 76 GALVFGRLGDLVGRKYTFLVTILIMGASTFIVGVLPNYNSIGITAPIILIILRILQGLAL 135 GAL+FGRLGDL GRK TFL+T+L+MG STF+VG+LP+Y IG+ API L+++R++QGLAL Sbjct: 90 GALIFGRLGDLWGRKNTFLITMLLMGVSTFVVGLLPSYAQIGVAAPIALVLMRLVQGLAL 149 Query: 136 GGEYGGAATYVAEHAPEGRRGSFTAWIQTTATMGLFLSLLVILGVRTAVGEAAFADWGWR 195 GGEYGGAATYVAEHAP G+RG +T+WIQTTAT+GLFLSL VIL R +GE AF WGWR Sbjct: 150 GGEYGGAATYVAEHAPPGKRGFYTSWIQTTATIGLFLSLAVILVARIQLGEEAFKAWGWR 209 Query: 196 IPFLVSILLLAISVWIRMSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILALVGL 255 IPFLVS+LLL +S+WIR+ ++ESP F +M AEGK SK PLTEAFG W NLK+V+LALVGL Sbjct: 210 IPFLVSLLLLGVSLWIRLKLHESPTFERMIAEGKGSKKPLTEAFGNWPNLKIVLLALVGL 269 Query: 256 TAGQAVVWYTGQFYALFFLTQTLKVDGPTANILIAAALLLATPFFLFFGSLSDKIGRKPI 315 T GQAVVWYTGQFYALFFL +TLK+DG AN L+A ALL+ TPFF+ G LSDKIGRKPI Sbjct: 270 TMGQAVVWYTGQFYALFFLEKTLKLDGALANTLVAVALLIGTPFFVICGWLSDKIGRKPI 329 Query: 316 ILGGCLIAAVTYFPIFSGLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTKKFTSS 375 I+ GCL+AA+TYFPIF +T +ANPAL A +PV+VTAD A+C FQF+ G KF + Sbjct: 330 IILGCLLAALTYFPIFKAITTYANPALAKAEATAPVVVTADTATCAFQFDLIGKAKFNTP 389 Query: 376 CDIVKAKLSAASVNYQNVAGAPGSVATVKIGDRIITSYDAAGLSKEDAAAKDKQLSKDLA 435 CD+ KA L+ A V+Y A G+ VK+GD + D+ G + + A K DL Sbjct: 390 CDVAKAYLAKAGVSYSVQAAPAGTPTAVKVGDVTLEGLDSKGATGQAFADARKAWEADLG 449 Query: 436 DDIKAAGYPSKADPEQMNKPMVLLLLFILVIYVTMVYGPIAACLVEMFPTRIRYTSMSMP 495 +KAAGYP+KAD +NKP V+ LL +LVIYVTMVYGPIAA LVE+FPTRIRYT+MS+P Sbjct: 450 AQLKAAGYPAKADAALVNKPAVIGLLALLVIYVTMVYGPIAAMLVELFPTRIRYTAMSLP 509 Query: 496 YHIGNGWFGGLLPTTSFALVAFKGDIYYGLWYPIVIAMITFVIGMLFVKETVRNNIHD 553 YHIGNGWFGG LPTT+FA+VA GDIY GLWYP++IA IT V+G LF+K+T N + D Sbjct: 510 YHIGNGWFGGFLPTTAFAIVAATGDIYSGLWYPVIIAAITAVVGGLFLKDTRHNRLED 567 >mlr0338 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 629 Score = 666 bits (1719), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/622 (58%), Positives = 436/622 (70%), Gaps = 73/622 (11%) Query: 4 ASVNTTARGITPEEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPN-TAFIFA 62 ++ T+RG+T EEKKVIFASSLGTVFEWYDFYLYGSLAA I FF+ T P T IFA Sbjct: 5 STAGRTSRGMTREEKKVIFASSLGTVFEWYDFYLYGSLAAFIGSTFFSPTIPEATRNIFA 64 Query: 63 LLAFAAGFIVRPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGVLPNYNSIGITAPI 122 LLAFAAGF+VRPFGALVFGR+GDLVGRKYTFLVT+ IMG STF+VG+LP Y ++GI AP+ Sbjct: 65 LLAFAAGFLVRPFGALVFGRIGDLVGRKYTFLVTMTIMGLSTFLVGLLPGYATLGIAAPV 124 Query: 123 ILIILRILQGLALGGEYGGAATYVAEHAPEGRRGSFTAWIQTTATMGLFLSLLVILGVRT 182 ILI LR+LQGLALGGEYGGAATYVAEHAP+ RRG +T+WIQTTAT+GLFLSL+VIL V+ Sbjct: 125 ILIALRMLQGLALGGEYGGAATYVAEHAPDDRRGFYTSWIQTTATLGLFLSLIVILIVQG 184 Query: 183 AVGEAAFADWGWRIPFLVSILLLAISVWIRMSMNESPAFLKMKAEGKTSKAPLTEAFGQW 242 ++ + +A WGWRIPF+VS +LLA+S+WIR+S++ESP F KMK EGK SKAPL+EAFGQW Sbjct: 185 SLSKETYAAWGWRIPFIVSFVLLAVSIWIRLSLSESPTFQKMKDEGKGSKAPLSEAFGQW 244 Query: 243 KNLKLVILALVGLTAGQAVVWYTGQFYALFFLTQTLKVDGPTANILIAAALLLATPFFLF 302 KN K+ +LAL+GLTAGQAVVWY GQFYALFFL LKVD + NI+IA AL L + FF+ Sbjct: 245 KNAKIALLALLGLTAGQAVVWYNGQFYALFFLQNVLKVDAQSVNIMIAIALALGSIFFVV 304 Query: 303 FGSLSDKIGRKPIILGGCLIAAVTYFPIFSGLTHFANPALEAALQKSPVIVTADPASCQF 362 FG LSDKIGRKPII+ G +A V FP+F LT ANPAL A Q + VTA P C+F Sbjct: 305 FGWLSDKIGRKPIIMAGLALAIVCTFPLFKALTWAANPALATAQQNTRATVTAAPGDCKF 364 Query: 363 QFNPTGTKKFTSSCDIVKAKLSAASVNYQNVA-GAPGSVATVKIGDRIITSY-------- 413 QFNP GT KFT+SCDI + L+ SV + V+ A G+ ATVKIG+ + SY Sbjct: 365 QFNPVGTAKFTTSCDIATSFLTKNSVPFDVVSTAAAGTPATVKIGNETVASYDAVAAGDQ 424 Query: 414 ----DAAGLSKEDAAAKD------------------------------------------ 427 DAA + + + KD Sbjct: 425 AKAKDAAFVKAVNMSLKDGGYPLKRAAIKVADQKLDAFIAANPELKLDAATIRGGEKATV 484 Query: 428 --KQLSKD-LADDIKAAGYPSK--------------ADPEQMNKPMVLLLLFILVIYVTM 470 +Q KD L +AAG P ADP +N PM + +LFILV++VTM Sbjct: 485 PTEQAVKDKLVTSEEAAGAPEVTVYNIPGGGAFAMFADPAAVNWPMTIGILFILVLFVTM 544 Query: 471 VYGPIAACLVEMFPTRIRYTSMSMPYHIGNGWFGGLLPTTSFALVAFKGDIYYGLWYPIV 530 VYGPIAA LVEMFPTRIRYT MS+PYHIGNGWFGGLLP T FAL A++GDIY+GLWYP+V Sbjct: 545 VYGPIAAILVEMFPTRIRYTGMSLPYHIGNGWFGGLLPATVFALSAYRGDIYFGLWYPVV 604 Query: 531 IAMITFVIGMLFVKETVRNNIH 552 IA +T +IGM+FVK+T+ ++ Sbjct: 605 IAAMTLIIGMIFVKDTLGTDLR 626