BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0565.p (384 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1632 [I] COG0183 Acetyl-CoA acetyltransferase Rso Ralstonia s... 556 e-158 PA2001 [I] COG0183 Acetyl-CoA acetyltransferase Pae Pseudomonas ... 502 e-142 CAC2873 [I] COG0183 Acetyl-CoA acetyltransferase Cac Clostridium... 474 e-133 ZyqeF [I] COG0183 Acetyl-CoA acetyltransferase EcZ Escherichia c... 462 e-130 ECs3701 [I] COG0183 Acetyl-CoA acetyltransferase Ecs Escherichia... 462 e-130 >RSc1632 [I] COG0183 Acetyl-CoA acetyltransferase Rso Ralstonia solanacearum Length = 393 Score = 556 bits (1432), Expect = e-158, Method: Compositional matrix adjust. Identities = 270/374 (72%), Positives = 317/374 (84%), Gaps = 1/374 (0%) Query: 1 MDDVVIVAAQRTAIGKFGGALSKIAAADLGAQVIKALLAKTGIKPEAISEVILGQVLTAG 60 M DVVIV+A RTA+GKFGG+L+KI A +LGA VI+ L++ + P+ +SEVI+GQVLTAG Sbjct: 1 MTDVVIVSAVRTAVGKFGGSLAKIPAPELGAAVIREALSRAKVAPDQVSEVIMGQVLTAG 60 Query: 61 LGQNPARQSVIKSGLPDMVPAFVVGKVCGSGLKAVQLAAQAIRCGDAQIVIAGGQENMSA 120 GQNPARQ++IK+GLPDMVP + KVCGSGLKAV LAA AI GDA IV+AGGQENMSA Sbjct: 61 SGQNPARQALIKAGLPDMVPGMTINKVCGSGLKAVMLAANAIVAGDADIVVAGGQENMSA 120 Query: 121 SPHVLNNSRDGFRMGDAKLTDTMIVDGLWDVYNQYHMGITAENVAKKFEISREEQDAFAA 180 +PHVL SRDGFRMGD KL D+MIVDGLWDVYNQYHMGITAENVAK++ I+RE QDAFA Sbjct: 121 APHVLPGSRDGFRMGDTKLIDSMIVDGLWDVYNQYHMGITAENVAKQYGITREAQDAFAV 180 Query: 181 ASQNKAEAAQKAGKFKDEIVPIEIKGKK-ETVVFDTDEFVKHGVTAESLATLRPAFDKAG 239 ASQNKAEAAQK+G+F DEIVPI I +K + + F DEFV+HG T ES+ L+PAFDKAG Sbjct: 181 ASQNKAEAAQKSGRFNDEIVPILIPQRKGDPIAFAQDEFVRHGATLESMTGLKPAFDKAG 240 Query: 240 TVTAGNASGINDGAAAVVVTSAKLAAELGLPVLAKIKAYSSAGLDPSIMGMGPVPASQLT 299 TVTA NASG+NDG AAVVV SA A ELGL LA I+AY++AG+DP +MGMGPVPAS+ Sbjct: 241 TVTAANASGLNDGGAAVVVMSAARAKELGLTPLATIRAYANAGVDPKVMGMGPVPASKRC 300 Query: 300 LKKAGWTPQDLDLMEINEAFAAQAIAVNKQMGWDTSKINVNGGAIALGHPIGASGCRVLV 359 L +AGW+ DLDLMEINEAFAAQA+AV++QMGWDT+K+NVNGGAIA+GHPIGASGCR+LV Sbjct: 301 LSRAGWSVGDLDLMEINEAFAAQALAVHQQMGWDTAKVNVNGGAIAIGHPIGASGCRILV 360 Query: 360 TLLHEMVRRDAKKG 373 TLLHEM +RDAKKG Sbjct: 361 TLLHEMQKRDAKKG 374 >PA2001 [I] COG0183 Acetyl-CoA acetyltransferase Pae Pseudomonas aeruginosa Length = 393 Score = 502 bits (1293), Expect = e-142, Method: Compositional matrix adjust. Identities = 244/374 (65%), Positives = 305/374 (81%), Gaps = 1/374 (0%) Query: 1 MDDVVIVAAQRTAIGKFGGALSKIAAADLGAQVIKALLAKTGIKPEAISEVILGQVLTAG 60 M DVVIVAA RTA+G F G+L+ I A +LGA VI+ LL +TG+ + EVILGQVLTAG Sbjct: 1 MQDVVIVAATRTAVGSFQGSLAGIPAPELGAAVIRRLLEQTGLDAGQVDEVILGQVLTAG 60 Query: 61 LGQNPARQSVIKSGLPDMVPAFVVGKVCGSGLKAVQLAAQAIRCGDAQIVIAGGQENMSA 120 GQNPARQ+ IK+GLP VPA + KVCGSGLKA+ L AQAIRCGDA++++AGGQENMS Sbjct: 61 SGQNPARQAAIKAGLPVGVPAMTLNKVCGSGLKALHLGAQAIRCGDAEVIVAGGQENMSL 120 Query: 121 SPHVLNNSRDGFRMGDAKLTDTMIVDGLWDVYNQYHMGITAENVAKKFEISREEQDAFAA 180 +P+V+ +R G RMG AKL D+MI DGLWD +N YHMGITAEN+A+K+ ++REEQDAFAA Sbjct: 121 APYVMPGARTGLRMGHAKLVDSMIEDGLWDAFNDYHMGITAENLAEKYGLTREEQDAFAA 180 Query: 181 ASQNKAEAAQKAGKFKDEIVPIEIKGKK-ETVVFDTDEFVKHGVTAESLATLRPAFDKAG 239 ASQ KA AA + G+F+DEI PI++ +K E + FDTDE + G T E+LA L+PAF K G Sbjct: 181 ASQQKAIAAIEGGRFRDEITPIQVPQRKGEPLGFDTDEQPRAGTTVEALAKLKPAFRKDG 240 Query: 240 TVTAGNASGINDGAAAVVVTSAKLAAELGLPVLAKIKAYSSAGLDPSIMGMGPVPASQLT 299 +VTAGNAS +NDGAAAV++ SA A LGLPVLA+I +Y+SAG+DP+IMG+GPV A++ Sbjct: 241 SVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLARIASYASAGVDPAIMGIGPVSATRRA 300 Query: 300 LKKAGWTPQDLDLMEINEAFAAQAIAVNKQMGWDTSKINVNGGAIALGHPIGASGCRVLV 359 L KAGW+ + LDL+E NEAFAAQ++AV +++GWD +++NVNGGAIALGHPIGASGCRVLV Sbjct: 301 LDKAGWSLEQLDLIEANEAFAAQSLAVGRELGWDAARVNVNGGAIALGHPIGASGCRVLV 360 Query: 360 TLLHEMVRRDAKKG 373 TLLHEM+RRDAKKG Sbjct: 361 TLLHEMIRRDAKKG 374 >CAC2873 [I] COG0183 Acetyl-CoA acetyltransferase Cac Clostridium acetobutylicum Length = 392 Score = 474 bits (1219), Expect = e-133, Method: Compositional matrix adjust. Identities = 233/373 (62%), Positives = 289/373 (77%) Query: 1 MDDVVIVAAQRTAIGKFGGALSKIAAADLGAQVIKALLAKTGIKPEAISEVILGQVLTAG 60 M +VVI +A RTAIG +G +L + A DLGA IK + K GIKPE ++EVILG VL AG Sbjct: 1 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAG 60 Query: 61 LGQNPARQSVIKSGLPDMVPAFVVGKVCGSGLKAVQLAAQAIRCGDAQIVIAGGQENMSA 120 LGQNPARQ+ K+GLP +PA + KVCGSGL+ V LAAQ I+ GDA ++IAGG ENMS Sbjct: 61 LGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSR 120 Query: 121 SPHVLNNSRDGFRMGDAKLTDTMIVDGLWDVYNQYHMGITAENVAKKFEISREEQDAFAA 180 +P++ NN+R G+RMG+AK D MI DGLWD +N YHMGITAEN+A+++ ISREEQD FA Sbjct: 121 APYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFAL 180 Query: 181 ASQNKAEAAQKAGKFKDEIVPIEIKGKKETVVFDTDEFVKHGVTAESLATLRPAFDKAGT 240 ASQ KAE A K+G+FKDEIVP+ IKG+K V DTDE + G T E LA L+PAF K GT Sbjct: 181 ASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAFKKDGT 240 Query: 241 VTAGNASGINDGAAAVVVTSAKLAAELGLPVLAKIKAYSSAGLDPSIMGMGPVPASQLTL 300 VTAGNASG+ND AA +V+ SA+ A ELG+ LAKI +Y SAG+DP+IMG GP A++ + Sbjct: 241 VTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYATKAAI 300 Query: 301 KKAGWTPQDLDLMEINEAFAAQAIAVNKQMGWDTSKINVNGGAIALGHPIGASGCRVLVT 360 +KAGWT +LDL+E NEAFAAQ++AV K + +D +K+NVNGGAIALGHPIGASG R+LVT Sbjct: 301 EKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGARILVT 360 Query: 361 LLHEMVRRDAKKG 373 L+H M +RDAKKG Sbjct: 361 LVHAMQKRDAKKG 373 >ZyqeF [I] COG0183 Acetyl-CoA acetyltransferase EcZ Escherichia coli O157:H7 EDL933 Length = 394 Score = 462 bits (1190), Expect = e-130, Method: Compositional matrix adjust. Identities = 222/373 (59%), Positives = 291/373 (78%) Query: 1 MDDVVIVAAQRTAIGKFGGALSKIAAADLGAQVIKALLAKTGIKPEAISEVILGQVLTAG 60 M DVVIV A RT IG F GAL+ +A +LG+ V+KAL+ +TG+ A+ EVILGQVLTAG Sbjct: 2 MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVPAYAVDEVILGQVLTAG 61 Query: 61 LGQNPARQSVIKSGLPDMVPAFVVGKVCGSGLKAVQLAAQAIRCGDAQIVIAGGQENMSA 120 GQNPARQS IK GLP+ V A + VCGSGLKA+ LA QAI+CG+A IVIAGGQENMS Sbjct: 62 AGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSR 121 Query: 121 SPHVLNNSRDGFRMGDAKLTDTMIVDGLWDVYNQYHMGITAENVAKKFEISREEQDAFAA 180 +PHVL +SR G ++G+++L D+++ DGLWD +N YH+G+TAEN+A+++ ISR+ QDA+A Sbjct: 122 APHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVTAENLAREYGISRQLQDAYAL 181 Query: 181 ASQNKAEAAQKAGKFKDEIVPIEIKGKKETVVFDTDEFVKHGVTAESLATLRPAFDKAGT 240 +SQ KA AA AG+FKDEIVP+ + +T+V DTDE +AE LA L P+FD G+ Sbjct: 182 SSQQKARAAIDAGRFKDEIVPVMTQSNGQTLVVDTDEQPHTDASAEGLARLNPSFDSLGS 241 Query: 241 VTAGNASGINDGAAAVVVTSAKLAAELGLPVLAKIKAYSSAGLDPSIMGMGPVPASQLTL 300 VTAGNAS INDGAAAV++ S A L LPVLA+I+A++S G+DP++MG+ PV A++ L Sbjct: 242 VTAGNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVDPALMGIAPVYATRRCL 301 Query: 301 KKAGWTPQDLDLMEINEAFAAQAIAVNKQMGWDTSKINVNGGAIALGHPIGASGCRVLVT 360 ++ GW D+DL+E NEAFAAQA++V K + WD ++NVNGGAIALGHPIGASGCR+LV+ Sbjct: 302 ERVGWQLADVDLIEANEAFAAQALSVGKMLEWDERRVNVNGGAIALGHPIGASGCRILVS 361 Query: 361 LLHEMVRRDAKKG 373 L+HEMV+R+A+KG Sbjct: 362 LVHEMVKRNARKG 374 >ECs3701 [I] COG0183 Acetyl-CoA acetyltransferase Ecs Escherichia coli O157:H7 Length = 394 Score = 462 bits (1190), Expect = e-130, Method: Compositional matrix adjust. Identities = 222/373 (59%), Positives = 291/373 (78%) Query: 1 MDDVVIVAAQRTAIGKFGGALSKIAAADLGAQVIKALLAKTGIKPEAISEVILGQVLTAG 60 M DVVIV A RT IG F GAL+ +A +LG+ V+KAL+ +TG+ A+ EVILGQVLTAG Sbjct: 2 MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVPAYAVDEVILGQVLTAG 61 Query: 61 LGQNPARQSVIKSGLPDMVPAFVVGKVCGSGLKAVQLAAQAIRCGDAQIVIAGGQENMSA 120 GQNPARQS IK GLP+ V A + VCGSGLKA+ LA QAI+CG+A IVIAGGQENMS Sbjct: 62 AGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSR 121 Query: 121 SPHVLNNSRDGFRMGDAKLTDTMIVDGLWDVYNQYHMGITAENVAKKFEISREEQDAFAA 180 +PHVL +SR G ++G+++L D+++ DGLWD +N YH+G+TAEN+A+++ ISR+ QDA+A Sbjct: 122 APHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVTAENLAREYGISRQLQDAYAL 181 Query: 181 ASQNKAEAAQKAGKFKDEIVPIEIKGKKETVVFDTDEFVKHGVTAESLATLRPAFDKAGT 240 +SQ KA AA AG+FKDEIVP+ + +T+V DTDE +AE LA L P+FD G+ Sbjct: 182 SSQQKARAAIDAGRFKDEIVPVMTQSNGQTLVVDTDEQPHTDASAEGLARLNPSFDSLGS 241 Query: 241 VTAGNASGINDGAAAVVVTSAKLAAELGLPVLAKIKAYSSAGLDPSIMGMGPVPASQLTL 300 VTAGNAS INDGAAAV++ S A L LPVLA+I+A++S G+DP++MG+ PV A++ L Sbjct: 242 VTAGNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVDPALMGIAPVYATRRCL 301 Query: 301 KKAGWTPQDLDLMEINEAFAAQAIAVNKQMGWDTSKINVNGGAIALGHPIGASGCRVLVT 360 ++ GW D+DL+E NEAFAAQA++V K + WD ++NVNGGAIALGHPIGASGCR+LV+ Sbjct: 302 ERVGWQLADVDLIEANEAFAAQALSVGKMLEWDERRVNVNGGAIALGHPIGASGCRILVS 361 Query: 361 LLHEMVRRDAKKG 373 L+HEMV+R+A+KG Sbjct: 362 LVHEMVKRNARKG 374