BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0538.p (319 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RP109 [C] COG0280 Phosphotransacetylase Rpr Rickettsia prowazekii 342 5e-94 CAC3076 [C] COG0280 Phosphotransacetylase Cac Clostridium acetob... 209 5e-54 TM1130 [C] COG0280 Phosphotransacetylase Tma Thermotoga maritima 206 5e-53 BS_yqiS [C] COG0280 Phosphotransacetylase Bsu Bacillus subtilis 192 1e-48 RC0147 [C] COG0280 Phosphotransacetylase Rco Rickettsia conorii 173 4e-43 >RP109 [C] COG0280 Phosphotransacetylase Rpr Rickettsia prowazekii Length = 351 Score = 342 bits (878), Expect = 5e-94, Method: Compositional matrix adjust. Identities = 174/302 (57%), Positives = 225/302 (74%), Gaps = 1/302 (0%) Query: 10 AERYDQLIRDALGAQAMRVAVVHPCSPEALQGALEARDEGLFEPVLVGPETRIRRIAEAA 69 A+ + L+ A G + ++ AVVHP E+L GA+ A + +P+L+GP+ +I +A+ Sbjct: 39 AKHFINLLLRADGLKPIKTAVVHPIDKESLLGAVRAAQFNVIKPILIGPQHKIESVAKVN 98 Query: 70 DISLQGLPIVPAEHSHAAAARAVEMAVAGEVGALMKGSLHSDELLGAVVGGASGLRTERR 129 D+ L+ ++ AEHSH AA +AVE+A EV A+MKG+LH+DEL+ AVV +GLRTERR Sbjct: 99 DVDLENYQVINAEHSHEAAKKAVELAKKREVAAIMKGALHTDELMSAVVYKENGLRTERR 158 Query: 130 ISHVYAMAIPAYPKPLIITDAAINIAPTLAHKRDICQNAIDLLHVMGVPRP-HVAVLAAV 188 ISH + MA+ +PKP IITDAAINI PTL KRDI QNAIDL+H++ + VAVL+AV Sbjct: 159 ISHAFLMAVATFPKPFIITDAAINIRPTLEDKRDIVQNAIDLMHIIKEDKQVRVAVLSAV 218 Query: 189 ETVNPAMPSTLDAAALTVMATRHQITGALVDGPLAFDNAISLQAASVKGIVSPVAGSADI 248 ETV A+P+TLDAAAL+ MA R QIT A+VDGPLAFDNAISL AA KGI SPV+G+ADI Sbjct: 219 ETVTSAIPTTLDAAALSKMADRGQITNAVVDGPLAFDNAISLFAAEAKGISSPVSGNADI 278 Query: 249 LLVPDLEAGNMLAKQLIYLSQADAAGLVLGARVPIILTSRADSLRVRLASSALARLVASR 308 L+VPDLE+GNMLAKQL YL QA AG+VLGARVPIILTSRAD + +R+ S LA + ++ Sbjct: 279 LVVPDLESGNMLAKQLKYLGQAVMAGIVLGARVPIILTSRADPIDMRVISCVLASFIYNQ 338 Query: 309 QR 310 + Sbjct: 339 TK 340 >CAC3076 [C] COG0280 Phosphotransacetylase Cac Clostridium acetobutylicum Length = 301 Score = 209 bits (533), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 112/299 (37%), Positives = 170/299 (56%) Query: 11 ERYDQLIRDALGAQAMRVAVVHPCSPEALQGALEARDEGLFEPVLVGPETRIRRIAEAAD 70 + ++++I + +VAV L+ +A+ G+ + +LVG I IA Sbjct: 3 KSFNEIIMKVKSKEMKKVAVAVAQDEPVLEAVRDAKKNGIADAILVGDHDEIVSIALKIG 62 Query: 71 ISLQGLPIVPAEHSHAAAARAVEMAVAGEVGALMKGSLHSDELLGAVVGGASGLRTERRI 130 + + IV + AA +AVE+ G+ +MKG +++ L +V+ GLRT + + Sbjct: 63 MDVNDFEIVNEPNVKKAALKAVELVSTGKADMVMKGLVNTATFLRSVLNKEVGLRTGKTM 122 Query: 131 SHVYAMAIPAYPKPLIITDAAINIAPTLAHKRDICQNAIDLLHVMGVPRPHVAVLAAVET 190 SHV + + L +TD A N P L K DI N++ + H +G+ P VA + AVE Sbjct: 123 SHVAVFETEKFDRLLFLTDVAFNTYPELKEKIDIVNNSVKVAHAIGIENPKVAPICAVEV 182 Query: 191 VNPAMPSTLDAAALTVMATRHQITGALVDGPLAFDNAISLQAASVKGIVSPVAGSADILL 250 +NP MPSTLDAA L+ M+ R QI G +VDGPLA D A+S +AA KG+ VAG ADI L Sbjct: 183 INPKMPSTLDAAMLSKMSDRGQIKGCVVDGPLALDIALSEEAAHHKGVTGEVAGKADIFL 242 Query: 251 VPDLEAGNMLAKQLIYLSQADAAGLVLGARVPIILTSRADSLRVRLASSALARLVASRQ 309 +P++E GN++ K L Y + + G+++G P++LTSRADS ++ S ALA LVA + Sbjct: 243 MPNIETGNVMYKTLTYTTDSKNGGILVGTSAPVVLTSRADSHETKMNSIALAALVAGNK 301 >TM1130 [C] COG0280 Phosphotransacetylase Tma Thermotoga maritima Length = 294 Score = 206 bits (524), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 123/295 (41%), Positives = 178/295 (60%), Gaps = 6/295 (2%) Query: 14 DQLIRDALGAQAMRVAVVHPCSPEALQGALEARDEGLFEPVLVGPETRIRRIAEAADISL 73 ++L+ A G + ++AV ++ A E + EPVL GPE I RI E Sbjct: 4 EKLVEMARG-KGKKLAVAAANDDHVIEAVYRAWRERVCEPVLFGPEEEITRIIEELVPEW 62 Query: 74 QGLPIV--PAEHSHAAAARAVEMAVAGEVGALMKGSLHSDELLGAVVGGASGLRTERRIS 131 + I+ P E A AVE GE LMKG + + +L+ + GLRT + ++ Sbjct: 63 KNPQIIDCPPEE---AGRLAVEAVSKGECDFLMKGKIKTGDLMKIYLDERYGLRTGKTMA 119 Query: 132 HVYAMAIPAYPKPLIITDAAINIAPTLAHKRDICQNAIDLLHVMGVPRPHVAVLAAVETV 191 V M IP +P+PLII+D + I+PTL K D+ ++ + + +VMG+ P VAV+ A+E V Sbjct: 120 MVSVMEIPDFPRPLIISDPGMLISPTLEQKVDMIEHCVRVANVMGLETPKVAVVGAIEVV 179 Query: 192 NPAMPSTLDAAALTVMATRHQITGALVDGPLAFDNAISLQAASVKGIVSPVAGSADILLV 251 NP MP T++AA L+ M R QI G +VDGP A DN +S +AA KGI SPVAG ADIL++ Sbjct: 180 NPKMPITMEAAILSKMNQRGQIKGCIVDGPFALDNVVSEEAAKKKGIQSPVAGKADILIL 239 Query: 252 PDLEAGNMLAKQLIYLSQADAAGLVLGARVPIILTSRADSLRVRLASSALARLVA 306 PD+EA N+L K L++L++A +A +LG +VP++LTSRADS + S AL+ + A Sbjct: 240 PDIEAANILYKALVFLAKAKSASTILGGKVPVVLTSRADSEETKFYSIALSAVFA 294 >BS_yqiS [C] COG0280 Phosphotransacetylase Bsu Bacillus subtilis Length = 299 Score = 192 bits (487), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 125/295 (42%), Positives = 171/295 (57%), Gaps = 16/295 (5%) Query: 17 IRDALGAQAMR----VAVVHPCSPEALQGALEARDEGLFEPVLVGPETRIRRIAEAADIS 72 ++D +G ++ +AV H E ++ A + +L G ++ + S Sbjct: 3 LKDLIGKASIHKNKTIAVAHAEDEEVIRAVKLAAEHLSARFLLTGDSKKLNELTS----S 58 Query: 73 LQG--LPIVPA---EHSHAAAARAVEMAVAGEVGALMKGSLHSDELLGAVVGGASGLRTE 127 +QG + IV A E S A RAV A LMKG++ + LL AV+ GLR+ Sbjct: 59 MQGHQVEIVHANTPEESAKLAVRAVHHKTAD---VLMKGNVPTSVLLKAVLNRQEGLRSA 115 Query: 128 RRISHVYAMAIPAYPKPLIITDAAINIAPTLAHKRDICQNAIDLLHVMGVPRPHVAVLAA 187 +SHV IP + + + +TD+A+NIAP+L R I QNA+ + H +G P A LAA Sbjct: 116 SVLSHVAVFDIPDFDRLMFVTDSAMNIAPSLEELRQILQNAVHVAHAVGNNMPKAAALAA 175 Query: 188 VETVNPAMPSTLDAAALTVMATRHQITGALVDGPLAFDNAISLQAASVKGIVSPVAGSAD 247 VETVNP M +T++AAAL M R QI G +VDGPLA DNA+S AA+ K I VAG+ D Sbjct: 176 VETVNPKMEATVNAAALAQMYKRGQIKGCIVDGPLALDNAVSQIAAAQKKISGDVAGNPD 235 Query: 248 ILLVPDLEAGNMLAKQLIYLSQADAAGLVLGARVPIILTSRADSLRVRLASSALA 302 ILLVP +EAGN+L K LIY ++A A ++ GA+ PI LTSRADS +L S ALA Sbjct: 236 ILLVPTIEAGNILYKSLIYFAKASVAAVITGAKAPIALTSRADSAENKLYSIALA 290 >RC0147 [C] COG0280 Phosphotransacetylase Rco Rickettsia conorii Length = 155 Score = 173 bits (439), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 91/136 (66%), Positives = 106/136 (77%), Gaps = 1/136 (0%) Query: 136 MAIPAYPKPLIITDAAINIAPTLAHKRDICQNAIDLLHVM-GVPRPHVAVLAAVETVNPA 194 M + +PKP IITDAAINI PTL KRDI QNAIDL+H++ + VAVL+ VETV A Sbjct: 1 MVVATFPKPFIITDAAINIRPTLEDKRDIVQNAIDLMHMIREDTQVRVAVLSVVETVTSA 60 Query: 195 MPSTLDAAALTVMATRHQITGALVDGPLAFDNAISLQAASVKGIVSPVAGSADILLVPDL 254 +P+TLDAAAL+ M R QIT A+VDGPLAFDNAISL AA K I S V+G+ADIL+VPDL Sbjct: 61 IPTTLDAAALSQMVDRGQITNAIVDGPLAFDNAISLFAAEAKCISSSVSGNADILVVPDL 120 Query: 255 EAGNMLAKQLIYLSQA 270 E+GNMLAKQL YL QA Sbjct: 121 ESGNMLAKQLKYLGQA 136