BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0008.0518.p         (119 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PA1966 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase P...    71   5e-13
VC2669 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase V...    64   7e-11
DRA0227 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase ...    62   2e-10

>PA1966 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase Pae
           Pseudomonas aeruginosa
          Length = 123

 Score = 71.2 bits (173), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 46/117 (39%), Positives = 67/117 (57%), Gaps = 3/117 (2%)

Query: 1   MPHLVMEYTGNLSIDVQPTLL--KLNQALVASGHFEENAIKARAVCLQNYLVGTDTQAQR 58
           MPHLV+E T NL ++  P  L  + N AL ASG F E  IK+R V L+ Y  GT    +R
Sbjct: 1   MPHLVIEATANLRLETSPGELLEQANAALFASGQFGEADIKSRFVTLEAYRQGT-AAVER 59

Query: 59  AFIALRLAILTGRSLEDKKQISDLLGAAMRQDLALPADTQVQITVEVADMQRESYYK 115
           A++   L+IL GR    ++ + + L   +   +A   +  VQ++VEV +M+R SY K
Sbjct: 60  AYLHACLSILDGRDAATRQALGESLCEVLAGAVAGGGEEGVQVSVEVREMERASYAK 116


>VC2669 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase Vch Vibrio
           cholerae
          Length = 116

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 41/118 (34%), Positives = 68/118 (57%), Gaps = 7/118 (5%)

Query: 1   MPHLVMEYTGNLS--IDVQPTLLKLNQALVASGHFEENAIKARAVCLQNYLVGTDTQAQR 58
           MP+LVMEY+ ++   I+VQ  L  L++A + SG FE +++K+RA+   ++L+G D     
Sbjct: 1   MPNLVMEYSNSVDERINVQGLLEDLHRAAIDSGLFEISSVKSRALRCHHWLIG-DEGDSV 59

Query: 59  AFIALRLAILTGRSLEDKKQISDLLGAAMRQDLALPADTQVQITVEVADMQRESYYKV 116
            FI L   +L GRS E K+++S      + + LA  A     +T+ + DM  + + KV
Sbjct: 60  DFIHLSFELLAGRSPEQKRELS----RKLMEILAAKASHVRSLTINIRDMDTDCFQKV 113


>DRA0227 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase Dra
           Deinococcus radiodurans
          Length = 128

 Score = 62.4 bits (150), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 43/118 (36%), Positives = 59/118 (50%), Gaps = 3/118 (2%)

Query: 1   MPHLVMEYTGNLSIDVQPTLL-KLNQALVASGH-FEENAIKARAVCLQNYLVGTDTQAQR 58
           MPHL +EYT NL     P LL KLN  L+A    F    I+ARA  L  Y +   ++   
Sbjct: 1   MPHLTLEYTDNLPEPRIPELLQKLNGVLLARPDIFPVGGIRARAYRLSEYALADSSEPSD 60

Query: 59  AFIALRLAILTGRSLEDKKQISDLLGAAMRQDLALP-ADTQVQITVEVADMQRESYYK 115
           AF+ LRL I  GRS E KK+  D L A +    A   A   + ++ E+++      +K
Sbjct: 61  AFVHLRLQIGAGRSEEVKKETGDALFAVLTDHFAAEFAQRGLMLSAEISEFSEAGTWK 118