BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0461.p (313 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2261 [G] COG0524 Sugar kinases, ribokinase family Pae Pseudomo... 340 3e-93 BS_kdgK [G] COG0524 Sugar kinases, ribokinase family Bsu Bacillu... 332 6e-91 CAC0395 [G] COG0524 Sugar kinases, ribokinase family Cac Clostri... 277 3e-74 L0021 [G] COG0524 Sugar kinases, ribokinase family Lla Lactococc... 249 8e-66 BH3724 [G] COG0524 Sugar kinases, ribokinase family Bha Bacillus... 225 8e-59 >PA2261 [G] COG0524 Sugar kinases, ribokinase family Pae Pseudomonas aeruginosa Length = 316 Score = 340 bits (871), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 167/306 (54%), Positives = 221/306 (72%), Gaps = 1/306 (0%) Query: 4 QLDVVTWGEALALLVADEVGPFEEVEKYTRRLAGAETNVAIGLARLGLKVGWASRVGNDA 63 +++ +GE +A+ VA++ G + VE++ +R+AGA++NVAIGLARLG V W SRVG+D+ Sbjct: 3 DFEILCFGETMAMFVAEQPGELDRVEQFGKRIAGADSNVAIGLARLGFAVAWLSRVGDDS 62 Query: 64 FGRFIRQRVAQEGVEVSRVITDREFRTAIQLKAKAVGGADPAIEYYRKGSAASHLSVDDF 123 GRF+ + +EG++ V D + T Q+K++ V GADP +EY+R+GSAAS L + Sbjct: 63 LGRFVLDSLTREGLDCRFVEVDAQAPTGFQMKSREVDGADPRVEYFRRGSAASRLGLAHI 122 Query: 124 DAGYFGAARHLHATGIAPALSATTMAFAHQAMDFMRGQGKTISFDPNLRPMLWPSQEVMA 183 GA RHLHATGI PALSA+ +H+ M MRG+G ++SFDPNLRP LWPS+ M Sbjct: 123 REEMLGA-RHLHATGIPPALSASACELSHELMRRMRGKGASLSFDPNLRPSLWPSERRMI 181 Query: 184 QQLNALAFKADWVLPGLSEGKILTGHDDAREIAGFYLERGVKLVVIKLGAEGAYWRNGQG 243 ++NALA A WVLPGL EG++L+G + +IA FYL+ GV V IKLG GAY+R+ G Sbjct: 182 AEINALAAHAHWVLPGLEEGRLLSGWQEPADIAAFYLDMGVDAVAIKLGPSGAYYRDAHG 241 Query: 244 EGRVAGVPVKEVVDTVGAGDGFAVGVISGMLEGLPVPQAVMRGNRIGAFAIQVVGDMEGL 303 EG V GVPV VVDTVGAGDGFAVGV+S +LEGLP+P AV RGN IG+ A+QV GDMEGL Sbjct: 242 EGLVPGVPVATVVDTVGAGDGFAVGVVSALLEGLPLPDAVARGNWIGSRAVQVRGDMEGL 301 Query: 304 PTRAEL 309 P R++L Sbjct: 302 PKRSQL 307 >BS_kdgK [G] COG0524 Sugar kinases, ribokinase family Bsu Bacillus subtilis Length = 324 Score = 332 bits (851), Expect = 6e-91, Method: Compositional matrix adjust. Identities = 168/308 (54%), Positives = 210/308 (68%), Gaps = 2/308 (0%) Query: 3 MQLDVVTWGEALALLVADEVGPFEEVEKYTRRLAGAETNVAIGLARLGLKVGWASRVGND 62 M+LD VT+GE++A+ A+E G EV +++ LAGAE+NVA GLARLG ++GW S+VGND Sbjct: 1 MKLDAVTFGESMAMFYANEYGGLHEVSTFSKGLAGAESNVACGLARLGFRMGWMSKVGND 60 Query: 63 AFGRFIRQRVAQEGVEVSRVI-TDREFRTAIQLKAKAVGGADPAIEYYRKGSAASHLSVD 121 G FI Q + +EGV+VSRVI + E T + LK+K G DP + YYRK SAAS L+ Sbjct: 61 QLGTFILQELKKEGVDVSRVIRSQDENPTGLLLKSKVKEG-DPQVTYYRKNSAASTLTTA 119 Query: 122 DFDAGYFGAARHLHATGIAPALSATTMAFAHQAMDFMRGQGKTISFDPNLRPMLWPSQEV 181 ++ YF A HLH TGI PALSA F + M+ MR GKTISFDPN+RP LWP Q Sbjct: 120 EYPRDYFQCAGHLHVTGIPPALSAEMKDFTYHVMNDMRNAGKTISFDPNVRPSLWPDQAT 179 Query: 182 MAQQLNALAFKADWVLPGLSEGKILTGHDDAREIAGFYLERGVKLVVIKLGAEGAYWRNG 241 M +N LA ADW PG++EG++LTG IA +YL++G V IKLG EGAY++ G Sbjct: 180 MVHTINDLAGLADWFFPGIAEGELLTGEKTPEGIADYYLKKGASFVAIKLGKEGAYFKTG 239 Query: 242 QGEGRVAGVPVKEVVDTVGAGDGFAVGVISGMLEGLPVPQAVMRGNRIGAFAIQVVGDME 301 EG + G V VVDTVGAGDGFAVGVISG+L+GL AV RGN IGA +Q GDM+ Sbjct: 240 TSEGFLEGCRVDRVVDTVGAGDGFAVGVISGILDGLSYKDAVQRGNAIGALQVQAPGDMD 299 Query: 302 GLPTRAEL 309 GLPTR +L Sbjct: 300 GLPTREKL 307 >CAC0395 [G] COG0524 Sugar kinases, ribokinase family Cac Clostridium acetobutylicum Length = 315 Score = 277 bits (708), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 143/309 (46%), Positives = 200/309 (64%), Gaps = 5/309 (1%) Query: 6 DVVTWGEALALLVAD---EVGP-FEEVEKYTRRLAGAETNVAIGLARLGLKVGWASRVGN 61 + +T GE LAL A+ E+ EV+ + + LAGAE NV++G++RLG + +++G Sbjct: 3 EFITIGEPLALFAAEGESEIDKRISEVDHFKKFLAGAEVNVSVGVSRLGHSAQYITKLGE 62 Query: 62 DAFGRFIRQRVAQEGVEVSRVITDREFRTAIQLKAKAVGGADPAIEYYRKGSAASHLSVD 121 D FG FIR+R+ +E V + + + T QLK+K G DP+I Y+RK SAA++ SV+ Sbjct: 63 DPFGEFIRRRLNEENVGTDYISSTNKKFTGFQLKSKVSEG-DPSIFYFRKNSAAANFSVE 121 Query: 122 DFDAGYFGAARHLHATGIAPALSATTMAFAHQAMDFMRGQGKTISFDPNLRPMLWPSQEV 181 D + +H+H TGI PALS +T ++ ++ + + T +FD NLRP LW S+E Sbjct: 122 DLNKVNLDGVKHVHITGIFPALSESTKEATYKLLELAKERNITTTFDTNLRPQLWNSKED 181 Query: 182 MAQQLNALAFKADWVLPGLSEGKILTGHDDAREIAGFYLERGVKLVVIKLGAEGAYWRNG 241 M +N +AFK+D +LPG++EG +L G D EIA FYL +GVKLV+IKLG++GAY + Sbjct: 182 MISTINDIAFKSDILLPGINEGLVLMGSDKPEEIADFYLNKGVKLVIIKLGSKGAYVKTK 241 Query: 242 QGEGRVAGVPVKEVVDTVGAGDGFAVGVISGMLEGLPVPQAVMRGNRIGAFAIQVVGDME 301 V G VK VVDTVGAGDGFAVGVIS +LEG+ V +AV RGN +GA A+ GD + Sbjct: 242 DEAYTVEGFKVKHVVDTVGAGDGFAVGVISAILEGISVKEAVRRGNAVGALAVMSEGDND 301 Query: 302 GLPTRAELE 310 G PT ELE Sbjct: 302 GYPTHEELE 310 >L0021 [G] COG0524 Sugar kinases, ribokinase family Lla Lactococcus lactis Length = 316 Score = 249 bits (635), Expect = 8e-66, Method: Compositional matrix adjust. Identities = 137/311 (44%), Positives = 199/311 (63%), Gaps = 7/311 (2%) Query: 6 DVVTWGEALALLVADEVG-PFEEVEKYTRRLAGAETNVAIGLARLGLKVGWASRVGNDAF 64 + +T GE L +L ++ + E +++ LAGAE NVAIGL+RLG K + S+VG D+F Sbjct: 3 EFITLGEPLVVLASENQDISLDVAEHFSKYLAGAELNVAIGLSRLGHKGIYLSKVGEDSF 62 Query: 65 GRFIRQRVAQEGVEVSRVITDREFRTAIQLKAKAVGGADPAIEYYRKGSAASHLSVDDFD 124 G FI + V + +E + + D+ + T LK K G DP ++YYRK SAA++LS+ + Sbjct: 63 GNFIIESVKKAEIETTYLTKDKNYSTGFYLKQKVSEG-DPKVDYYRKNSAAANLSIAELK 121 Query: 125 AGYFGAARHLHATGIAPALSATTMAFAHQAMDFMRGQGKTIS-FDPNLRPMLWPSQEVMA 183 A + H +GI PALS T++ QA + + ++ FDPNLRP+LW +QE M Sbjct: 122 ALDLSGIKIAHLSGIFPALSETSLK-TFQAFNQKLNEADILTIFDPNLRPVLWDNQEKMI 180 Query: 184 QQLNALAFKADWVLPGLSEGKILTGHDDAREIAGFYLERG--VKLVVIKLGAEGAYWRNG 241 + +N LA ++ +LPG++EG+ILTG + +IA FYLE+ K+VV+KLGA+GA+ + Sbjct: 181 RTINDLAKQSQIILPGINEGEILTGSSEPEKIANFYLEQSPLTKIVVVKLGADGAFVKLK 240 Query: 242 QGEGR-VAGVPVKEVVDTVGAGDGFAVGVISGMLEGLPVPQAVMRGNRIGAFAIQVVGDM 300 GE V+G V +VVDTVGAGDGFAVG+ S +LEG + +AV R +GA A+Q GD Sbjct: 241 NGEQYFVSGFKVAKVVDTVGAGDGFAVGLESALLEGKTLKEAVKRACAVGALAVQSSGDS 300 Query: 301 EGLPTRAELEA 311 EG PT+ EL+A Sbjct: 301 EGYPTKEELKA 311 >BH3724 [G] COG0524 Sugar kinases, ribokinase family Bha Bacillus halodurans Length = 317 Score = 225 bits (574), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 131/310 (42%), Positives = 182/310 (58%), Gaps = 2/310 (0%) Query: 5 LDVVTWGEALALLVADEVGPFEEVEKYTRRLAGAETNVAIGLARLGLKVGWASRVGNDAF 64 +DVVT+GE + + E+G V+++ + + GAE+NVAIG+A+LG VGW S+VGND Sbjct: 1 MDVVTFGETMVVFEPVEMGALRYVDRFKKGVGGAESNVAIGVAKLGHSVGWVSKVGNDEL 60 Query: 65 GRFIRQRVAQEGVEVSRVITDREFRTAIQLKAKAVGGADPAIEYYRKGSAASHLSVDDFD 124 G+++ + EGV+ S+V+ D T + LK K + + YYR GSAAS L V+D + Sbjct: 61 GKYVISAIRGEGVDTSQVVLDDGAPTGLYLKEKLRDDFN-RVYYYRAGSAASRLGVEDIN 119 Query: 125 AGYFGAARHLHATGIAPALSATTMAFAHQAMDFMRGQGKTISFDPNLRPMLWPSQEVMAQ 184 Y A+ +H TGI P LS + H +DF + G SFDPNLR L + + Sbjct: 120 WAYMKQAKIIHITGITPLLSDSCYELCHAVLDFAKENGIFASFDPNLRMKLLANVPDGKE 179 Query: 185 QLNALAFKADWVLPGLSEGKILTGHDDAREIAGFYLERGVKLVVIKLGAEGAYW-RNGQG 243 +L ALA KAD V+PG E L D+ ++ L VVIK GA+GA++ G+ Sbjct: 180 RLLALASKADLVMPGRDEAAFLFDTDELAQMFSRLLTGRTTSVVIKDGAKGAHFMEEGKE 239 Query: 244 EGRVAGVPVKEVVDTVGAGDGFAVGVISGMLEGLPVPQAVMRGNRIGAFAIQVVGDMEGL 303 V PV +VVD VGAGDGFA GV++ +LEG + +AV G +IGA + GDMEGL Sbjct: 240 PQFVPSCPVDKVVDPVGAGDGFAAGVLASLLEGKSMEEAVSVGTQIGALVVMAKGDMEGL 299 Query: 304 PTRAELEAAS 313 P R +LEA S Sbjct: 300 PEREQLEAFS 309