BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0449.p (223 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0937 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 219 3e-57 BMEI0462 [LR] COG0494 NTP pyrophosphohydrolases including oxidat... 165 6e-41 AGc4093 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 159 7e-39 mll2727 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 146 3e-35 CC0407 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 146 4e-35 >RSc0937 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Rso Ralstonia solanacearum Length = 202 Score = 219 bits (559), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 111/203 (54%), Positives = 141/203 (69%), Gaps = 9/203 (4%) Query: 24 RLNADWLRQRFADPPRWEPEHSGDQMARLAESKGRFRLASVLIPIVLREQGMTILFTRRT 83 RL ++R+R PP W PEH+ + +RL ++ + R A+VL+P+V R G+T+L T+R Sbjct: 2 RLTPAFVRERLHAPPSWVPEHTDE--SRLIDTSLKLREAAVLVPLVQRSAGLTVLLTQRN 59 Query: 84 ADLKDHAGQISFPGGRREDYDGSAIETALRETEEEIGLARQHIEVIGSLPDYFTGTGYRV 143 A L HAGQISFPGG RE D A++TALRET EE+G+ +H+EV+G LPDY TG+G+ V Sbjct: 60 ATLSQHAGQISFPGGGRESSDRDAVDTALRETVEEVGIGAEHVEVVGRLPDYITGSGFHV 119 Query: 144 TPVAGLIQPPFEAVGDPREVAEIFEVPLAFLMDGVNHQRRSVELPAPVGRRSFYTMPYE- 202 +PV GL+ P F A DP EVAE+FEVPLAFLMD NH+ R + V R FY MPY Sbjct: 120 SPVVGLLTPGFIARPDPSEVAEVFEVPLAFLMDPANHEVRELRWDDRV--RCFYAMPYRR 177 Query: 203 ----RYFIWGATAGMLRNLFHFL 221 RYFIWGATAGMLRNL+H L Sbjct: 178 PGGGRYFIWGATAGMLRNLYHLL 200 >BMEI0462 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Bme Brucella melitensis Length = 207 Score = 165 bits (418), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 88/190 (46%), Positives = 118/190 (62%), Gaps = 9/190 (4%) Query: 39 RWEPEH---SGDQM----ARLAESKGRFRLASVLIPIVLREQGMTILFTRRTADLKDHAG 91 +W P+H +GD A R R A+VL+P+V R T+L TRRT L+ H+G Sbjct: 18 QWRPDHEELTGDHALNPDVSQAMVTARMRDAAVLVPVVDRGAEATLLLTRRTDTLRKHSG 77 Query: 92 QISFPGGRREDYDGSAIETALRETEEEIGLARQHIEVIGSLPDYFTGTGYRVTPVAGLIQ 151 QI+FPGG + DG+ ALRE EEIGLA E+IG+LP Y TG+G+ +TPV +++ Sbjct: 78 QIAFPGGAIDPEDGTTERAALREANEEIGLAADRAEIIGNLPRYLTGSGFSITPVLAVVK 137 Query: 152 PPFEAVGDPREVAEIFEVPLAFLMDGVNHQRRSVELPAPVGRRSFYTMPYERYFIWGATA 211 PF+ +P EVA+IFEVPL+FLM+ NH+R S R +Y MPY FIWGATA Sbjct: 138 TPFDVHPNPDEVADIFEVPLSFLMNPANHRRESRLFNGK--ERFYYAMPYHERFIWGATA 195 Query: 212 GMLRNLFHFL 221 G++R L+ L Sbjct: 196 GIIRGLYERL 205 >AGc4093 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 210 Score = 159 bits (401), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 79/162 (48%), Positives = 108/162 (66%), Gaps = 2/162 (1%) Query: 58 RFRLASVLIPIVLREQGMTILFTRRTADLKDHAGQISFPGGRREDYDGSAIETALRETEE 117 R + A+VLIP++ ++FT+RTA L+ H+GQISFPGG + D + E ALRETEE Sbjct: 47 RLKDAAVLIPVIDDGNDARVIFTQRTATLRQHSGQISFPGGGIDAEDRTPEEAALRETEE 106 Query: 118 EIGLARQHIEVIGSLPDYFTGTGYRVTPVAGLIQPPFEAVGDPREVAEIFEVPLAFLMDG 177 EIGL+R +E +G LPDY +GTG+R+ PV +++P F+ +P EV E+FEVPL+FLMD Sbjct: 107 EIGLSRSFVETVGRLPDYISGTGFRIKPVLSVVRPGFDLTLNPTEVDEVFEVPLSFLMDP 166 Query: 178 VNHQRRSVELPAPVGRRSFYTMPYERYFIWGATAGMLRNLFH 219 NH R S R FY MPY +IWG TAG++R ++ Sbjct: 167 ANHGRGSRIFQGK--ERFFYEMPYGERYIWGITAGIVRTIYE 206 >mll2727 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Mlo Mesorhizobium loti Length = 204 Score = 146 bits (369), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 88/201 (43%), Positives = 115/201 (57%), Gaps = 15/201 (7%) Query: 30 LRQRFADPPRWEPEHSGDQMA---------RLAESKGRFRLASVLIPIVLREQGMTILFT 80 R RFA P H+GD RL + K R A+VLIP++ E T+L T Sbjct: 8 FRARFAAQPD---AHAGDDYGDHRFNPGHPRLNQGKP-LRNAAVLIPVIDHEGEATVLLT 63 Query: 81 RRTADLKDHAGQISFPGGRREDYDGSAIETALRETEEEIGLARQHIEVIGSLPDYFTGTG 140 +R L++H+GQ++FPGG + D S ALRET EEIGL + IE+IG +PDY G+G Sbjct: 64 KRAEKLRNHSGQVAFPGGTIDATDASPEAAALRETFEEIGLDQHRIEIIGRMPDYVAGSG 123 Query: 141 YRVTPVAGLIQPPFEAVGDPREVAEIFEVPLAFLMDGVNHQRRSVELPAPVGRRSFYTMP 200 YR+ PV G+++P F+ + EV FEVPL FLMD VNH+R S FY MP Sbjct: 124 YRIAPVLGIVRPGFQLDLNADEVDAAFEVPLRFLMDPVNHKRDSRMWNDL--EWFFYDMP 181 Query: 201 YERYFIWGATAGMLRNLFHFL 221 Y IWG TAG++R L+ L Sbjct: 182 YGDRRIWGVTAGIIRTLYERL 202 >CC0407 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Ccr Caulobacter vibrioides Length = 216 Score = 146 bits (368), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 82/164 (50%), Positives = 100/164 (60%), Gaps = 2/164 (1%) Query: 59 FRLASVLIPIVLREQGMTILFTRRTADLKDHAGQISFPGGRREDYDGSAIETALRETEEE 118 R A+VL+ +V + G TIL TRR L+ H GQI+FPGGR D + TALRE +EE Sbjct: 46 LRPAAVLVGLVEHDDGPTILLTRRADTLRSHTGQIAFPGGRC-DPGETPWGTALREAQEE 104 Query: 119 IGLARQHIEVIGSLPDYFTGTGYRVTPVAGLIQPPFEAVGDPREVAEIFEVPLAFLMDGV 178 +GL + V G L Y T TG+ VTPV G I P P EVA++FE P FLMD Sbjct: 105 VGLDPALVTVAGLLHGYQTVTGFHVTPVVGFIDPKATFTPSPEEVADVFETPFDFLMDPA 164 Query: 179 NHQRRSVELPAPVGRRSFYTMPYERYFIWGATAGMLRNLFHFLR 222 NHQR+ E+P RR FY MP+ FIWGATAGMLR+L+ L Sbjct: 165 NHQRQHREVPG-GPRRHFYAMPWNDRFIWGATAGMLRSLYEALH 207