BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0390.p (287 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC2426 [NOU] COG1989 Type II secretory pathway, prepilin signal ... 254 1e-67 NMB0332 [NOU] COG1989 Type II secretory pathway, prepilin signal... 243 5e-64 NMA2156 [NOU] COG1989 Type II secretory pathway, prepilin signal... 238 1e-62 RSc2827 [NOU] COG1989 Type II secretory pathway, prepilin signal... 217 2e-56 PA4528 [NOU] COG1989 Type II secretory pathway, prepilin signal ... 215 1e-55 >VC2426 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Vch Vibrio cholerae Length = 291 Score = 254 bits (650), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 146/272 (53%), Positives = 183/272 (67%), Gaps = 12/272 (4%) Query: 17 ALAALLGLLVGSFLNVLIHRLPIMMLRE-----SANFVAQERGETPPHHDRYDLWLPSSS 71 LA L GL+VGSFLNV+I+RLP +M RE +A+F E G TPP + L LP S+ Sbjct: 13 VLATLFGLIVGSFLNVVIYRLPKIMEREWRAECAASF--PEYGITPPE-GKLTLSLPRST 69 Query: 72 CPHCATPLPWRHKLPVLSWLLLRGRCGHCQAAIGLRYPLVELLTAALFAFAAWRFGLGVT 131 CPHC TP+ +P+LSWL LRG+C HC+A I RYPL+ELLTA + A F GV Sbjct: 70 CPHCQTPIRVIDNIPLLSWLALRGQCSHCKAPISARYPLIELLTALMSLVIATHFPFGVF 129 Query: 132 GLAVMACTATLVALAFIDAQTMLLPDDLTLPLMWLGL-LVNLTHRLVPLQDAVLGAAAGY 190 +A++ + L+A FID T+LLPD LTLPL+W G+ L L V L DAV+GA AGY Sbjct: 130 AVALLFFSYVLIAATFIDFDTLLLPDQLTLPLLWGGIALALLGFSPVSLSDAVIGAMAGY 189 Query: 191 GVLWLIFWLFKLITGKDGLGYGDFKLMAALGAWLGWQALPVILLLASAMGAVLGLVLMAA 250 LW I+WLFKL+TGK+G+GYGDFKL+AALGAWLGWQ LPVI+LL+S +G + GL+ + Sbjct: 190 LSLWSIYWLFKLLTGKEGMGYGDFKLLAALGAWLGWQQLPVIVLLSSVVGVIFGLIQLRQ 249 Query: 251 GRHRRGQAIPFGPCLASAGLLALLQG---LDW 279 + A PFGP LA AG ALL G +DW Sbjct: 250 QKKGIDMAFPFGPYLAIAGWFALLWGDKVIDW 281 >NMB0332 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Nme Neisseria meningitidis MC58 Length = 286 Score = 243 bits (619), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 133/276 (48%), Positives = 177/276 (64%), Gaps = 9/276 (3%) Query: 12 DPILCALAALLGLLVGSFLNVLIHRLPIMMLRESANFVAQERGETPPHHDR---YDLWLP 68 P LAA+ GLLVGSFLNV+I+R+P+MM R F A+E P + ++L P Sbjct: 8 SPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVF-AKEYLNLPLTEEESRTFNLMKP 66 Query: 69 SSSCPHCATPLPWRHKLPVLSWLLLRGRCGHCQAAIGLRYPLVELLTAALFAFAAWRFGL 128 S CP C P+ +P++S+LLLRG+C CQ I +RYPL+ELLT LF AW++G Sbjct: 67 DSCCPKCRVPIRAWQNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGW 126 Query: 129 GVTGLAVMACTATLVALAFIDAQTMLLPDDLTLPLMWLGLLVNLTHRLVPLQDAVLGAAA 188 L + TA L++L FIDA T LPD +TLPL+WLGL+ NL VPLQ AVLGA A Sbjct: 127 SWITLGGLVLTAFLISLTFIDADTQYLPDSMTLPLIWLGLIFNLDGGFVPLQSAVLGAVA 186 Query: 189 GYGVLWLIFWLFKLITGKDGLGYGDFKLMAALGAWLGWQALPVILLLASAMGAVLGLVLM 248 GYG LWL+ ++KL+TGK G+G GDFKL+AALGAWLG ALPV++ ++S +G V +V+ Sbjct: 187 GYGSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLVAAIVM- 245 Query: 249 AAGRHRRGQAIPFGPCLASAGLLALLQGLDWLWRGL 284 R +GQ FGP L +G + + D +WR + Sbjct: 246 ---RVAKGQHFAFGPALTVSGWI-IFTANDSVWRAV 277 >NMA2156 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases NmA Neisseria meningitidis Z2491 Length = 286 Score = 238 bits (608), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 131/276 (47%), Positives = 176/276 (63%), Gaps = 9/276 (3%) Query: 12 DPILCALAALLGLLVGSFLNVLIHRLPIMMLRESANFVAQERGETPPHHDR---YDLWLP 68 P LAA+ GLLVGSFLNV+I+R+P+MM R F A+E P + ++L P Sbjct: 8 SPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVF-AKEYLNLPLTEEESRTFNLMKP 66 Query: 69 SSSCPHCATPLPWRHKLPVLSWLLLRGRCGHCQAAIGLRYPLVELLTAALFAFAAWRFGL 128 S CP C P+ +P++S+LLLRG+C CQ I +RYPL+ELLT LF AW++G Sbjct: 67 DSCCPKCRVPIRAWQNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGW 126 Query: 129 GVTGLAVMACTATLVALAFIDAQTMLLPDDLTLPLMWLGLLVNLTHRLVPLQDAVLGAAA 188 L + TA L++L FIDA T LPD +TLPL+WLGL+ NL VPLQ AVLGA A Sbjct: 127 SWITLGGLILTAFLISLTFIDADTQYLPDSMTLPLIWLGLIFNLDGGFVPLQSAVLGAVA 186 Query: 189 GYGVLWLIFWLFKLITGKDGLGYGDFKLMAALGAWLGWQALPVILLLASAMGAVLGLVLM 248 GYG +WL+ ++KLI G+ G+G GDFKL+AALGAWLG ALPV++ ++S +G V +V+ Sbjct: 187 GYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLVAAIVM- 245 Query: 249 AAGRHRRGQAIPFGPCLASAGLLALLQGLDWLWRGL 284 R +GQ FGP L +G + + D +WR + Sbjct: 246 ---RVAKGQHFAFGPALTVSGWI-IFTANDSVWRAV 277 >RSc2827 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Rso Ralstonia solanacearum Length = 294 Score = 217 bits (553), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 136/256 (53%), Positives = 171/256 (66%), Gaps = 1/256 (0%) Query: 21 LLGLLVGSFLNVLIHRLPIMMLRESANFVAQERGETPPHHDRYDLWLPSSSCPHCATPLP 80 LLGLLVGSFLNV+IHRLP M+ RE AN++A+ R E PH + Y+L +P S+CP C + Sbjct: 25 LLGLLVGSFLNVVIHRLPRMIEREEANYIAELRNEPLPHPEPYNLVVPRSACPSCGHQIK 84 Query: 81 WRHKLPVLSWLLLRGRCGHCQAAIGLRYPLVELLTAALFAFAAWRFGLGVTGLAVMACTA 140 +PVLSWL LRGRC C+ I RYP VEL+T L W FG +A A Sbjct: 85 AVENIPVLSWLALRGRCSACKTPISWRYPAVELVTGVLTGACLWHFGPTWVAVASAALLW 144 Query: 141 TLVALAFIDAQTMLLPDDLTLPLMWLGLLVNLTHRLVPLQDAVLGAAAGYGVLWLIFWLF 200 L+A + IDA T LLPD +T PL+WLGLLVNL L DAV+GA AGY LW I+W + Sbjct: 145 FLIAGSMIDADTQLLPDAITQPLLWLGLLVNLFSMFARLPDAVIGATAGYLFLWAIYWAY 204 Query: 201 KLITGKDGLGYGDFKLMAALGAWLGWQALPVILLLASAMGAVLGLVLMAAGRHRRGQAIP 260 KL+ G++G+GYGDFKLM ALGAW GWQALP+++LL+S +G V G+V +A G Sbjct: 205 KLLRGREGMGYGDFKLMGALGAWFGWQALPLLVLLSSVVGLVFGVVRIARGATSE-SPFS 263 Query: 261 FGPCLASAGLLALLQG 276 FGP +A AG++ALL G Sbjct: 264 FGPFIAGAGVIALLAG 279 >PA4528 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Pae Pseudomonas aeruginosa Length = 290 Score = 215 bits (547), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 143/282 (50%), Positives = 185/282 (65%), Gaps = 12/282 (4%) Query: 1 MPFLEAYAL-PGDPILCALAALLGLLVGSFLNVLIHRLPIMMLRESANFVAQERG----E 55 MP L+ A P +LC + LLGLLVGSFLNV++HRLP MM R N+ A+ R E Sbjct: 1 MPLLDYLASHPLAFVLCTI--LLGLLVGSFLNVVVHRLPKMMER---NWKAEAREALGLE 55 Query: 56 TPPHHDRYDLWLPSSSCPHCATPL-PWRHKLPVLSWLLLRGRCGHCQAAIGLRYPLVELL 114 P Y+L LP+S+CP C + PW + +P++S+L L G+C C+AAIG RYPLVEL Sbjct: 56 PEPKQATYNLVLPNSACPRCGHEIRPWEN-IPLVSYLALGGKCSSCKAAIGKRYPLVELA 114 Query: 115 TAALFAFAAWRFGLGVTGLAVMACTATLVALAFIDAQTMLLPDDLTLPLMWLGLLVNLTH 174 TA L + AW FG A++ T L+A++ IDA LLPD L LPL+WLGL+ N Sbjct: 115 TALLSGYVAWHFGFTWQAGAMLLLTWGLLAMSLIDADHQLLPDVLVLPLLWLGLIANHFG 174 Query: 175 RLVPLQDAVLGAAAGYGVLWLIFWLFKLITGKDGLGYGDFKLMAALGAWLGWQALPVILL 234 L DA+ GA GY LW +FWLFKL+TGK+G+GYGDFKL+A LGAW GWQ LP+ +L Sbjct: 175 LFASLDDALFGAVFGYLSLWSVFWLFKLVTGKEGMGYGDFKLLAMLGAWGGWQILPLTIL 234 Query: 235 LASAMGAVLGLVLMAAGRHRRGQAIPFGPCLASAGLLALLQG 276 L+S +GA+LG++++ G IPFGP LA AG +ALL G Sbjct: 235 LSSLVGAILGVIMLRLRNAESGTPIPFGPYLAIAGWIALLWG 276