BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0386.p (440 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2824 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Rso ... 469 e-132 VC0558 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Vch V... 319 1e-86 YPO3298 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Ype ... 307 4e-83 PM1185 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Pmu P... 300 6e-81 STM2679 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Sty ... 299 8e-81 >RSc2824 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Rso Ralstonia solanacearum Length = 425 Score = 469 bits (1208), Expect = e-132, Method: Compositional matrix adjust. Identities = 236/424 (55%), Positives = 310/424 (73%), Gaps = 17/424 (4%) Query: 2 QVLALFILILLSAFFSMTETALMAANRHRLRHLAKQGNRAAVTILWLLDRTERLLSLVLI 61 Q+ A+ +L+ SAFFS++ET+LMA NRHRLRHLAK A LL +T++LLSL+LI Sbjct: 9 QLGAVVLLLCCSAFFSISETSLMALNRHRLRHLAKSNVAGARRTQGLLGQTDKLLSLILI 68 Query: 62 ANTAINALATALVTALAIAAFGNHQRVITAATACVAALLIIFAEIVPKVIGATYPERISL 121 N IN L+ LAI FGN ++ ATA VA L+I+F EI PK+ GATYPERIS Sbjct: 69 GNNLINTAVPVLIANLAIHYFGNSGTTLSIATAIVAFLIIVFCEIAPKIAGATYPERISF 128 Query: 122 FTGFILKPLMRVAKPLIWFVNLFVSAILRLLRIKTGARQRISPEELRSIVRAAEQRISPE 181 FI+ PL+R+A PL+ VN FV+ +LRL+RI RQ A EQR+S E Sbjct: 129 PASFIIAPLLRLATPLVTVVNAFVTVLLRLVRIN--PRQ------------APEQRMSAE 174 Query: 182 ELRSIVLEGGSFIPQKHKSILLNLFDLEKISVEDVMTPRSQVEALNLAAPVDDILHQLAT 241 ELR++VLE G+FIP KH+SILLNLFDL+ I+V+DVMTPR++VE+L+L+ P+++++ QL T Sbjct: 175 ELRTLVLESGNFIPHKHRSILLNLFDLDAITVDDVMTPRARVESLDLSRPIEEVIQQLET 234 Query: 242 CYHNKLPVFEGEINHIVGILHVRKTVSLFRREEEISHDDIRELLSAPYYVPVETDVFTQL 301 CYHNKLPVFE + + ++GILHVRK +SL E I HDD R LL+ PY+VP T VF QL Sbjct: 235 CYHNKLPVFEQDTDQVLGILHVRKALSLLGHAELI-HDDFRSLLAKPYFVPSGTPVFRQL 293 Query: 302 QYFQENHERLGVVVDEYGEVQGLVTLEDIIEEMIGEFTTSSPGSSGEGFGWDKDGACLLE 361 QYFQEN R+G+V++EYG++ GLVTLEDIIEEMIGEFTT+ P + WD A L + Sbjct: 294 QYFQENRRRIGLVINEYGDMLGLVTLEDIIEEMIGEFTTTLPNAG--KLAWDAQNAYLAD 351 Query: 362 GSTTLRDINKRLGLQLPLDGPKTINGLLLEYLQDIPEASVAVKMDGCVIEIVQVQNQAIR 421 +LRD+N+RLGLQLP DGPKT+NGL+LE L++IPEA V+V++ GCV++IVQ+ +Q+IR Sbjct: 352 AGMSLRDLNRRLGLQLPTDGPKTLNGLVLEVLEEIPEAPVSVRIAGCVMDIVQMDSQSIR 411 Query: 422 MVKL 425 V+L Sbjct: 412 TVRL 415 >VC0558 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Vch Vibrio cholerae Length = 426 Score = 319 bits (817), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 161/420 (38%), Positives = 266/420 (63%), Gaps = 16/420 (3%) Query: 6 LFILILLSAFFSMTETALMAANRHRLRHLAKQGNRAAVTILWLLDRTERLLSLVLIANTA 65 L LI++SA+FS +ET +MA NR+RL+HLA G++ A + LLDR +RL+ L+LI N Sbjct: 13 LACLIIISAYFSGSETGMMALNRYRLKHLANSGHKGAKRVEKLLDRPDRLIGLILIGNNL 72 Query: 66 INALATALVTALAIAAFGNHQRVITAATACVAALLIIFAEIVPKVIGATYPERISLFTGF 125 +N LA+A+ T + + +G+ + AT + ++++FAE+ PK + A YPER+S + Sbjct: 73 VNILASAIATIIGMRLYGDLG--VAIATGALTLVILVFAEVTPKTLAALYPERVSYASSV 130 Query: 126 ILKPLMRVAKPLIWFVNLFVSAILRLLRIKTGARQRISPEELRSIVRAAEQRISPEELRS 185 +L LM++ PL+ FVNL + ++R+L I SP+ + +S EELR+ Sbjct: 131 LLTILMKLLSPLVLFVNLMTNGLIRILGI--------SPKHGKG------DHLSSEELRT 176 Query: 186 IVLEGGSFIPQKHKSILLNLFDLEKISVEDVMTPRSQVEALNLAAPVDDILHQLATCYHN 245 +V E G IP++H+ +LL++ DLE ++V D+M PR+++ +N+ I+ QL H Sbjct: 177 VVNEAGGLIPRRHQDMLLSILDLEHVTVNDIMIPRNEITGININDDWKSIVRQLVHSPHG 236 Query: 246 KLPVFEGEINHIVGILHVRKTVSLFRREEEISHDDIRELLSAPYYVPVETDVFTQLQYFQ 305 ++ ++ +I+ +VGIL +R+ + + + + + Y++P T + QL FQ Sbjct: 237 RVVLYRDKIDEVVGILRLREASRFMLEKNDFNKEMLLRAADEIYFIPEGTPLNVQLLKFQ 296 Query: 306 ENHERLGVVVDEYGEVQGLVTLEDIIEEMIGEFTTSSPGSSGEGFGWDKDGACLLEGSTT 365 N ER+G++VDEYGE+ GL TLEDI+EE++GEFTTS S + DG+ L+EGS Sbjct: 297 RNKERIGLIVDEYGEIIGLTTLEDILEEIVGEFTTSMSPSLADEITPQGDGSFLIEGSAN 356 Query: 366 LRDINKRLGLQLPLDGPKTINGLLLEYLQDIPEASVAVKMDGCVIEIVQVQNQAIRMVKL 425 +RDINK L +LP DGP+T+NGL+LE+L++IP + ++VK+ +EI++++ I++VK+ Sbjct: 357 IRDINKSLKWKLPTDGPRTLNGLILEHLEEIPASHLSVKVAQHKMEILELEENRIKLVKV 416 >YPO3298 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Ype Yersinia pestis Length = 427 Score = 307 bits (786), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 153/419 (36%), Positives = 259/419 (61%), Gaps = 17/419 (4%) Query: 13 SAFFSMTETALMAANRHRLRHLAKQGNRAAVTILWLLDRTERLLSLVLIANTAINALATA 72 SA+FS +ET +M NR+R+RHL+KQGNRAA + LL+R +RL+SLVLI N +N LA+A Sbjct: 21 SAYFSASETGMMTLNRYRMRHLSKQGNRAARRVEKLLNRPDRLISLVLIGNNLVNILASA 80 Query: 73 LVTALAIAAFGNHQRVITAATACVAALLIIFAEIVPKVIGATYPERISLFTGFILKPLMR 132 L T + I +G+ + AT + +++IFAE++PK I A YPER++ + +L PL + Sbjct: 81 LATIVGIRLYGDAG--VAIATGVLTFVILIFAEVLPKTIAALYPERVAFPSSMLLAPLQK 138 Query: 133 VAKPLIWFVNLFVSAILRLLRIKTGARQRISPEELRSIVRAAEQRISPEELRSIVLEGGS 192 + PL+W +N ++ L I+ + +S +ELR+IV E S Sbjct: 139 IMLPLVWLLNTITRGLMHLCGIRGNVH--------------SSDAMSKDELRTIVSESQS 184 Query: 193 FIPQKHKSILLNLFDLEKISVEDVMTPRSQVEALNLAAPVDDILHQLATCYHNKLPVFEG 252 I ++++ +L+++ DLEK++V D+M PR++V +++ I+ QL H ++ ++ Sbjct: 185 KISRRNQDMLISVLDLEKVTVSDIMVPRNEVVGIDINDDWKSIMRQLTHSPHGRIVLYRQ 244 Query: 253 EINHIVGILHVRKTVSLFRREEEISHDDIRELLSAPYYVPVETDVFTQLQYFQENHERLG 312 ++ +G+L VR+ L ++E + +++ Y++P T + QL FQ N +++G Sbjct: 245 SLDDAIGMLRVREAYRLMTEKKEFNKENLLRAADEIYFIPEGTPLNVQLVKFQRNKKKVG 304 Query: 313 VVVDEYGEVQGLVTLEDIIEEMIGEFTTSSPGSSGEGFGWDKDGACLLEGSTTLRDINKR 372 ++VDEYG++QGLVT+EDI+EE++G+FTTS + E DG+ L++GS ++R++NK Sbjct: 305 MIVDEYGDIQGLVTVEDILEEIVGDFTTSMSPTLAEEVNPQSDGSVLIDGSASVREVNKA 364 Query: 373 LGLQLPLDGPKTINGLLLEYLQDIPEASVAVKMDGCVIEIVQVQNQAIRMVKLIALAQA 431 LP+D +TING+LLE L++IP+A + V++ IE++ VQ I+ VK+ + A Sbjct: 365 FNWSLPVDA-RTINGMLLEELEEIPQAHIHVRLGNYQIEVLDVQENMIKRVKITPMTSA 422 >PM1185 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Pmu Pasteurella multocida Length = 419 Score = 300 bits (767), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 160/417 (38%), Positives = 260/417 (62%), Gaps = 18/417 (4%) Query: 13 SAFFSMTETALMAANRHRLRHLAKQGNRAAVTILWLLDRTERLLSLVLIANTAINALATA 72 SA+FS +ET L++ANR+RLRHLA++G+R A LL +T+ LLSL+LI N +N A+A Sbjct: 20 SAYFSGSETGLLSANRYRLRHLAEKGHRGAKKAEKLLKKTDVLLSLILICNNLVNITASA 79 Query: 73 LVTALAIAAFGNHQRVITAATACVAALLIIFAEIVPKVIGATYPERISLFTGFILKPLMR 132 + T + + +G+ I AT + +++IFAEI+PK I A YPE+++ + +L +R Sbjct: 80 ITTIIGMRLYGDAGVAI--ATGALTFVMLIFAEILPKTIAARYPEKVAFTSSHLLSVFLR 137 Query: 133 VAKPLIWFVNLFVSAILRLLRIKTGARQRISPEELRSIVRAAEQRISPEELRSIVLEGGS 192 + PL++ +NL + IL LLR+K+ + +SPEELRSIV E G Sbjct: 138 LFTPLVYLMNLIIQGILALLRLKSDNKS---------------TSLSPEELRSIVNESGK 182 Query: 193 FIPQKHKSILLNLFDLEKISVEDVMTPRSQVEALNLAAPVDDILHQLATCYHNKLPVFEG 252 FIP H+ +LL++ DLE ++V+D+M PR+ + +++ I+ QL H ++ +++G Sbjct: 183 FIPSAHQEMLLSILDLEGVTVDDIMVPRNDIGGIDIDDDWKAIMRQLNHAAHGRVVLYKG 242 Query: 253 EIN-HIVGILHVRKTVSLFRREEEISHDDIRELLSAPYYVPVETDVFTQLQYFQENHERL 311 ++ +I+G+L VR+ L + E + + + Y++P T + +QL F+ N ER+ Sbjct: 243 NMDENILGMLRVREAYRLMLDKNEFNKETLIRAADEVYFIPEGTPLNSQLLNFRNNKERI 302 Query: 312 GVVVDEYGEVQGLVTLEDIIEEMIGEFTTSSPGSSGEGFGWDKDGACLLEGSTTLRDINK 371 G+VVDEYG+++GLVTLEDI+EE++GEFTTS+ S + DG+ ++EGS LRD+NK Sbjct: 303 GLVVDEYGDIKGLVTLEDILEEIVGEFTTSTAPSINDEVIPQSDGSLIIEGSANLRDLNK 362 Query: 372 RLGLQLPLDGPKTINGLLLEYLQDIPEASVAVKMDGCVIEIVQVQNQAIRMVKLIAL 428 L + +T NGL+LE+L++IPE +++G I I++V + I+ K+I L Sbjct: 363 LFDWNLDTEDARTFNGLILEHLEEIPEEGTVCEINGLQITILEVNDNMIKQAKVIKL 419 >STM2679 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Sty Salmonella typhimurium LT2 Length = 413 Score = 299 bits (766), Expect = 8e-81, Method: Compositional matrix adjust. Identities = 155/418 (37%), Positives = 262/418 (62%), Gaps = 16/418 (3%) Query: 9 LILLSAFFSMTETALMAANRHRLRHLAKQGNRAAVTILWLLDRTERLLSLVLIANTAINA 68 ++++SA+FS +ET +M NR+RLRH+AKQGNR+A + LL + +RL+SLVLI N +N Sbjct: 1 MVVISAYFSGSETGMMTLNRYRLRHMAKQGNRSAKRVEKLLRKPDRLISLVLIGNNLVNI 60 Query: 69 LATALVTALAIAAFGNHQRVITAATACVAALLIIFAEIVPKVIGATYPERISLFTGFILK 128 LA+AL T + + +G+ + AT + ++++FAE++PK I A YPE+++ + F+L Sbjct: 61 LASALGTIVGMRLYGDAG--VAIATGVLTFVVLVFAEVLPKTIAALYPEKVAYPSSFLLA 118 Query: 129 PLMRVAKPLIWFVNLFVSAILRLLRIKTGARQRISPEELRSIVRAAEQRISPEELRSIVL 188 PL + PL+W +N ++RL+ IKT IV + +S EELR+IV Sbjct: 119 PLQILMMPLVWLLNTITRLLMRLMGIKT------------DIVVSGS--LSKEELRTIVH 164 Query: 189 EGGSFIPQKHKSILLNLFDLEKISVEDVMTPRSQVEALNLAAPVDDILHQLATCYHNKLP 248 E S I ++++ +LL++ DLEK+SV+D+M PR+++ +++ I QL H ++ Sbjct: 165 ESRSQISRRNQDMLLSVLDLEKVSVDDIMVPRNEIIGIDINDDWKSIERQLTHSPHGRIV 224 Query: 249 VFEGEINHIVGILHVRKTVSLFRREEEISHDDIRELLSAPYYVPVETDVFTQLQYFQENH 308 ++ ++ + +L VR+ L ++E + + + YYVP T + TQL FQ N Sbjct: 225 LYRDSLDDAISMLRVREAWRLMAEKKEFTKEMMLRAADEIYYVPEGTPLSTQLIKFQRNK 284 Query: 309 ERLGVVVDEYGEVQGLVTLEDIIEEMIGEFTTSSPGSSGEGFGWDKDGACLLEGSTTLRD 368 +++G+VV+EYG++QGLVT+EDI+EE++G+FTTS + E DG+ +++G+ +R+ Sbjct: 285 KKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMSPTLAEEVTPQNDGSVIIDGTANVRE 344 Query: 369 INKRLGLQLPLDGPKTINGLLLEYLQDIPEASVAVKMDGCVIEIVQVQNQAIRMVKLI 426 INK LP D +T+NG++LE L++IP A V+++ I+I+ VQ I+ VK++ Sbjct: 345 INKAFNWHLPEDDARTVNGVILEALEEIPVAGTRVRIEQYDIDILDVQENMIKQVKVV 402