BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0364.p (387 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2805 [F] COG0209 Ribonucleotide reductase, alpha subunit Rso ... 531 e-150 PA1156 [F] COG0209 Ribonucleotide reductase, alpha subunit Pae P... 436 e-122 CT827 [F] COG0209 Ribonucleotide reductase, alpha subunit Ctr Ch... 334 2e-91 CPn0984 [F] COG0209 Ribonucleotide reductase, alpha subunit Cpn ... 306 7e-83 VNG2384G [F] COG0209 Ribonucleotide reductase, alpha subunit Hbs... 251 1e-66 >RSc2805 [F] COG0209 Ribonucleotide reductase, alpha subunit Rso Ralstonia solanacearum Length = 987 Score = 531 bits (1368), Expect = e-150, Method: Compositional matrix adjust. Identities = 255/339 (75%), Positives = 290/339 (85%), Gaps = 1/339 (0%) Query: 1 VLYRAKRMEERAQQGAATKTEVVAPQLHVTEDGQSRPLDINEVRSLIAAACVGLEEHVDG 60 VLYR +R +ERAQ G T+ + L+VT+ G +RPLD+ +R+LI +AC GL E VD Sbjct: 126 VLYRERRSQERAQAGE-TQQQPAFIGLNVTDGGITRPLDMAALRNLIVSACAGLGESVDP 184 Query: 61 EAILAETVKNLYDGVPVEELYKSAILAARALMEKDPAYSQVTSRLLMHTIRKEVFGKEVA 120 E IL ETVKNLY+GVP+ ++Y SAILAAR L+EKDPAYSQ T+R+L+HTIR+E+ G+EV Sbjct: 185 EPILKETVKNLYEGVPMSQVYDSAILAARTLIEKDPAYSQATARILLHTIRREILGEEVT 244 Query: 121 QADAPAEYLEYFPQYVKKGIEAELLDTKLAQFDLAKLAAALKPERDLQFGYIGLQTLYDR 180 QA+ Y +YFPQ++K+GI A LLD LAQFDLAKL AAL RDLQF Y+GLQTLYDR Sbjct: 245 QAEMAGRYADYFPQFIKRGINAGLLDDTLAQFDLAKLGAALDASRDLQFNYLGLQTLYDR 304 Query: 181 YFLHIGGTRIEMPQAFYMRVAMGLALNEIDRETRAIEFYDLLSSFDFMSSTPTLFNSGTQ 240 YFLHI RIEMPQAF+MRVAMGL+LNEIDRE RAIEFY LLSSFDFMSSTPTLFNSGT Sbjct: 305 YFLHISDKRIEMPQAFFMRVAMGLSLNEIDREARAIEFYQLLSSFDFMSSTPTLFNSGTC 364 Query: 241 RSQLSSCYLTTVADDLDGIYEAIKENALLAKFAGGLGNDWTPVRALGAHIKGTNGKSQGV 300 RSQLSSCYLTTV+DDLDGIYEA+KENALL+KFAGGLGNDWT VRALG+HIKGTNGKSQGV Sbjct: 365 RSQLSSCYLTTVSDDLDGIYEALKENALLSKFAGGLGNDWTNVRALGSHIKGTNGKSQGV 424 Query: 301 VPFLKVVNDTAVAVNQGGKRKGAVCAYLETWHMDIEEFL 339 VPFLKVVNDTAVAVNQGGKRKGAVCAYLETWH+DIEEFL Sbjct: 425 VPFLKVVNDTAVAVNQGGKRKGAVCAYLETWHLDIEEFL 463 >PA1156 [F] COG0209 Ribonucleotide reductase, alpha subunit Pae Pseudomonas aeruginosa Length = 963 Score = 436 bits (1120), Expect = e-122, Method: Compositional matrix adjust. Identities = 219/345 (63%), Positives = 260/345 (75%), Gaps = 7/345 (2%) Query: 1 VLYRAKRMEERAQQGAATKTEVVAPQLHVTE-DGQSRPLDINEVRSLIAAACVGLEEHVD 59 V+YR R ER GAA+ P + +T DG PLD+ + ++I+ AC GL E VD Sbjct: 122 VIYREARAAERKNAGAASDVAQPHPSIRITRADGSLSPLDMGRLNTIISEACEGLAE-VD 180 Query: 60 GEAILAETVKNLYDGVPVEELYKSAILAARALMEKDPAYSQVTSRLLMHTIRKEVFG--- 116 G I ET+KNLYDGV +++ + ++ AR L+E++P YS VT+RLLM T+R E G Sbjct: 181 GALIERETLKNLYDGVAEKDVNTALVMTARTLVEREPNYSYVTARLLMDTLRAEALGFLG 240 Query: 117 -KEVAQADAPAE-YLEYFPQYVKKGIEAELLDTKLAQFDLAKLAAALKPERDLQFGYIGL 174 E A AE Y + P Y++KG E EL+D KL +FDL KL A+ ERD QF Y+GL Sbjct: 241 VAESATHHEMAELYAKALPAYIEKGAEFELVDAKLKEFDLEKLGKAIDHERDQQFTYLGL 300 Query: 175 QTLYDRYFLHIGGTRIEMPQAFYMRVAMGLALNEIDRETRAIEFYDLLSSFDFMSSTPTL 234 QTLYDRYF+H G R E+PQ F+MRVAMGLA+ E DRE RAIEFY+LLSSFD+MSSTPTL Sbjct: 301 QTLYDRYFIHKDGIRFELPQIFFMRVAMGLAIEEKDREARAIEFYNLLSSFDYMSSTPTL 360 Query: 235 FNSGTQRSQLSSCYLTTVADDLDGIYEAIKENALLAKFAGGLGNDWTPVRALGAHIKGTN 294 FN+GT R QLSSCYLTTV DDL GIY AI +NA+L+KFAGGLGNDWTPVRALG++IKGTN Sbjct: 361 FNAGTLRPQLSSCYLTTVPDDLSGIYGAIHDNAMLSKFAGGLGNDWTPVRALGSYIKGTN 420 Query: 295 GKSQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLETWHMDIEEFL 339 GKSQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLETWH+DIEEFL Sbjct: 421 GKSQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLETWHLDIEEFL 465 >CT827 [F] COG0209 Ribonucleotide reductase, alpha subunit Ctr Chlamydia trachomatis Length = 1047 Score = 334 bits (857), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 168/343 (48%), Positives = 228/343 (66%), Gaps = 5/343 (1%) Query: 1 VLYRAKRM---EERAQQGAATKTEVVAPQLHVTEDGQSRPLDINEVRSLIAAACVGLEEH 57 +LYR R + R + G+ KT +++DG + + +++ + +A AC E Sbjct: 209 ILYREARARVRDNREEDGSTEKTIAEEAVEVLSKDGSTYTMTHSQLLAHLARACSRFPET 268 Query: 58 VDGEAILAETVKNLYDGVPVEELYKSAILAARALMEKDPAYSQVTSRLLMHTIRKEVFGK 117 D + N Y G+ E+ + I+AARA +EK+P Y+ V + LL+ + KE GK Sbjct: 269 TDAALLTDMAFANFYSGIKESEVVLACIMAARANIEKEPDYAFVAAELLLDVVYKEALGK 328 Query: 118 EVAQADAPAEYLEYFPQYVKKGIEAELLDTKLAQ-FDLAKLAAALKPERDLQFGYIGLQT 176 D + ++F +Y+ +G + L+ +L FDL LA A+ RDLQF Y+G+Q Sbjct: 329 SKYAEDLEQAHRDHFKRYIAEG-DTYRLNAELKHLFDLDALADAMDLSRDLQFSYMGIQN 387 Query: 177 LYDRYFLHIGGTRIEMPQAFYMRVAMGLALNEIDRETRAIEFYDLLSSFDFMSSTPTLFN 236 LYDRYF H G R+E PQ F+MRVAMGLALNE D+ + AI FY+LLS+F + +TPTLFN Sbjct: 388 LYDRYFNHHEGCRLETPQIFWMRVAMGLALNEQDKTSWAITFYNLLSTFRYTPATPTLFN 447 Query: 237 SGTQRSQLSSCYLTTVADDLDGIYEAIKENALLAKFAGGLGNDWTPVRALGAHIKGTNGK 296 SG + SQLSSCYL+TV D+L IY+ I +NA+L+K+AGG+GNDWT +RA GA IKGTNG+ Sbjct: 448 SGMRHSQLSSCYLSTVQDNLVNIYKVIADNAMLSKWAGGIGNDWTAIRATGALIKGTNGR 507 Query: 297 SQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLETWHMDIEEFL 339 SQGV+PF+KV NDTAVAVNQGGKRKGAVC YLE WH+D E+FL Sbjct: 508 SQGVIPFIKVTNDTAVAVNQGGKRKGAVCVYLEVWHLDYEDFL 550 >CPn0984 [F] COG0209 Ribonucleotide reductase, alpha subunit Cpn Chlamydophila pneumoniae CWL029 Length = 1044 Score = 306 bits (783), Expect = 7e-83, Method: Compositional matrix adjust. Identities = 152/310 (49%), Positives = 208/310 (67%), Gaps = 2/310 (0%) Query: 31 EDGQSRPLDINEVRSLIAAACVGLEEHVDGEAILAETVKNLYDGVPVEELYKSAILAARA 90 EDG + L ++ + AC + D + + NLY G+ +E+ + I+AARA Sbjct: 240 EDGTTYLLRKTDLEKRFSWACKRFPKTTDSQLLADMAFMNLYSGIKEDEVTTACIMAARA 299 Query: 91 LMEKDPAYSQVTSRLLMHTIRKEVFGKEVAQADAPAEYLEYFPQYVKKGIEAELLDTKLA 150 +E++P Y+ + + LL ++ +E G + + ++F +Y+ G E L + +L Sbjct: 300 NIEREPDYAFIAAELLTSSLYEETLGCSSQDPNLSEIHKKHFKEYILNGEEYRL-NPQLK 358 Query: 151 QFDLAKLAAALKPERDLQFGYIGLQTLYDRYFLHIGGTRIEMPQAFYMRVAMGLALNEID 210 +DL L+ L RD QF Y+G+Q LYDRYF G R+E Q F+MRV+MGLALNE + Sbjct: 359 DYDLDALSEVLDLSRDQQFSYMGVQNLYDRYFNLHEGRRLETAQIFWMRVSMGLALNEGE 418 Query: 211 RET-RAIEFYDLLSSFDFMSSTPTLFNSGTQRSQLSSCYLTTVADDLDGIYEAIKENALL 269 ++ AI FY+LLS+F + +TPTLFNSG + SQLSSCYL+TV DDL IY+ I +NALL Sbjct: 419 QKNFWAITFYNLLSTFRYTPATPTLFNSGMRHSQLSSCYLSTVKDDLSHIYKVISDNALL 478 Query: 270 AKFAGGLGNDWTPVRALGAHIKGTNGKSQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLE 329 +K+AGG+GNDWT VRA GA IKGTNGKSQGV+PF+KV NDTA+AVNQGGKRKGA+C YLE Sbjct: 479 SKWAGGIGNDWTDVRATGAVIKGTNGKSQGVIPFIKVANDTAIAVNQGGKRKGAMCVYLE 538 Query: 330 TWHMDIEEFL 339 WH+D E+FL Sbjct: 539 NWHLDYEDFL 548 >VNG2384G [F] COG0209 Ribonucleotide reductase, alpha subunit Hbs Halobacterium sp. NRC-1 Length = 804 Score = 251 bits (642), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 135/302 (44%), Positives = 190/302 (62%), Gaps = 7/302 (2%) Query: 43 VRSLIAAACVGLEEHVDGEA---ILAETVKNLYDGVPVEELYKSAILAARALMEKDPAYS 99 V + + A E+ +D +A IL E +N YD +E Y + + A +++ PAY Sbjct: 12 VAAALDRALTDHEDDIDSDARDRILTEATRNAYDDATTDERYDALLGALTGRIDRHPAYK 71 Query: 100 QVTSRLLMHTIRKEVFGKEVAQADAPAEYLEYFPQYVKKGIEAELLDTKLAQFDLAKLAA 159 V R+L + + + + A A + F +++G++A+LLD ++ +DL +LA Sbjct: 72 TVAGRVLRERLERRL-VDDYDPATRDAATRQAFRDGIQRGLDADLLDERMGDYDLNRLAD 130 Query: 160 ALKPERDLQFGYIGLQTLYDRYFL-HIGGTRIEMPQAFYMRVAMGLALNE--IDRETRAI 216 A+ P RD + Y+ + TL RYFL E+PQ F+MRVAMG+AL E DRE AI Sbjct: 131 AITPARDDRLDYMAMDTLRQRYFLREPDADPFELPQPFWMRVAMGVALREDPADREEYAI 190 Query: 217 EFYDLLSSFDFMSSTPTLFNSGTQRSQLSSCYLTTVADDLDGIYEAIKENALLAKFAGGL 276 EFYD LS+ F+ STPTLF++GT +QLSSCYLTTV DDLDGI++A KE+A L+K++GGL Sbjct: 191 EFYDALSTLRFVHSTPTLFHAGTTHAQLSSCYLTTVPDDLDGIFDAYKEHAKLSKWSGGL 250 Query: 277 GNDWTPVRALGAHIKGTNGKSQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLETWHMDIE 336 GNDWTP+RA G+ I+ T +S G VPFLK+ ND A+N+ GKR+GA AYL WH+D Sbjct: 251 GNDWTPLRAAGSLIESTGVESTGTVPFLKISNDVTAAINRSGKRRGAAAAYLACWHLDFP 310 Query: 337 EF 338 F Sbjct: 311 AF 312