BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0008.0352.p         (174 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc2784 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ...   159   3e-39
XF1990 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins X...    84   2e-16
NMB0006 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ...    83   3e-16
NMA0253 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ...    82   6e-16
FN2067 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins F...    77   3e-14

>RSc2784 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Rso
           Ralstonia solanacearum
          Length = 174

 Score =  159 bits (402), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 79/173 (45%), Positives = 106/173 (61%), Gaps = 1/173 (0%)

Query: 2   MKKLRNVILLAVVAVVCVGIGLYASHRAHPADSAETQALNRLLAQSLPDATGQMQSLAQY 61
           M + + +I L +  +V   +G+YA HRA         A+       LPDA G    L+ +
Sbjct: 1   MSRRQTLIALILAGIVAAVLGVYAGHRATQPRPPADGAVTAFFDARLPDANGTPIDLSAF 60

Query: 62  RGKPLIVNFWATWCGPCVEEMPELTALQQE-IAPVQILGIGVDSQENIGKFAQKYQIRYP 120
           RG+P+++NFWA WCGPCVEEMPEL+AL QE  A V+ +GIG+DS  NI  F  K  + YP
Sbjct: 61  RGQPVVINFWAPWCGPCVEEMPELSALAQEQKARVKFIGIGIDSAANIQAFLGKVPVTYP 120

Query: 121 LFVAGTGATDLLRQFGNQAGGLPFTALVGKDGNVKKIYLGRLKFDELRQDLSQ 173
           + VAG G T+L RQ GNQAGGLPFT ++   G +    +GR+  DELR  L +
Sbjct: 121 IAVAGFGGTELGRQLGNQAGGLPFTVILNAQGEITFRKMGRVHADELRAALQR 173


>XF1990 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Xfa Xylella
           fastidiosa 9a5c
          Length = 211

 Score = 83.6 bits (205), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 66/114 (57%), Gaps = 9/114 (7%)

Query: 53  GQMQSLAQYRGKPLIVNFWATWCGPCVEEMPELTALQQEIAPVQILGIGVDSQ--ENIGK 110
           G++  LA +RGK ++VN WATWC PC++EMPEL+AL +    V+++G+  D    E I  
Sbjct: 87  GEVYDLAAHRGKWVLVNVWATWCEPCLKEMPELSALHRRRRDVEVVGLAYDDSKPEEIRT 146

Query: 111 FAQKYQIRYPLFVAGTGATDLLRQFGNQAG--GLPFTALVGKDGNVKKIYLGRL 162
           F + + + YP+ +      D+     N A   GLP + L+  DG V K +LG +
Sbjct: 147 FLRSHPVVYPIIL-----VDISNPPKNFAAPRGLPMSYLIAPDGTVAKQFLGSI 195


>NMB0006 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Nme
           Neisseria meningitidis MC58
          Length = 160

 Score = 82.8 bits (203), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 46/131 (35%), Positives = 69/131 (52%), Gaps = 13/131 (9%)

Query: 20  GIGLYASHRAHPADSAETQALNRLLAQSLPDATGQMQSLAQYRGKPLIVNFWATWCGPCV 79
            I L A+  AH A + E         QSL       QSL   +    IVN WATWCGPC 
Sbjct: 8   AITLAATFAAHTASADELAGWKDNTPQSL-------QSL---KAPVRIVNLWATWCGPCR 57

Query: 80  EEMPELTAL--QQEIAPVQILGIGVDSQENIGKFAQKYQIRYPLF-VAGTGATDLLRQFG 136
           +EMP ++     Q+   V ++GI +D+ +NIG F ++  + YP++   G  + + ++ +G
Sbjct: 58  KEMPAMSKWYKAQKKGSVDMVGIALDTSDNIGNFLKQTPVSYPIWRYTGANSRNFMKTYG 117

Query: 137 NQAGGLPFTAL 147
           N  G LPFT +
Sbjct: 118 NTVGVLPFTVV 128


>NMA0253 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins NmA
           Neisseria meningitidis Z2491
          Length = 160

 Score = 82.0 bits (201), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 48/153 (31%), Positives = 74/153 (48%), Gaps = 13/153 (8%)

Query: 20  GIGLYASHRAHPADSAETQALNRLLAQSLPDATGQMQSLAQYRGKPLIVNFWATWCGPCV 79
            I L A+  AH A + E         QSL       QSL   +    IVN WATWCGPC 
Sbjct: 8   AITLAATFAAHTASADELAGWKDNTPQSL-------QSL---KAPVRIVNLWATWCGPCQ 57

Query: 80  EEMPELTAL--QQEIAPVQILGIGVDSQENIGKFAQKYQIRYPLF-VAGTGATDLLRQFG 136
           +EMP ++     Q+   V ++GI +D+ +NIG F ++  + YP++      + + ++ +G
Sbjct: 58  KEMPAMSKWYKAQKKGSVDMVGIALDTSDNIGNFLKQTPVSYPIWRYTEANSRNFMKSYG 117

Query: 137 NQAGGLPFTALVGKDGNVKKIYLGRLKFDELRQ 169
           N  G LPFT +       K+   G +    L +
Sbjct: 118 NNVGVLPFTVVEAPKCGYKQTITGEVNEKSLTE 150


>FN2067 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Fnu
           Fusobacterium nucleatum
          Length = 164

 Score = 76.6 bits (187), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 21/142 (14%)

Query: 48  LPDATGQMQSLAQYRGKPLIVNFWATWCGPCVEEMPELTALQQEIAP----VQILGI-GV 102
           L D  G+  ++ +Y+GK +++NFWATWCG CVEEMP    + +E       V ILG+ G 
Sbjct: 23  LYDQYGKKHNIEEYKGKVVVINFWATWCGYCVEEMPGFEKVYKEFGSNKKDVIILGVAGP 82

Query: 103 DSQENIGK----------FAQKYQIRYPLFVAGTGATDLLRQFGN-QAGGLPFTALVGKD 151
            S+EN+            F +K  I YP  +  TG     + F + +   LP T ++ K+
Sbjct: 83  KSKENLNNVDVEKDKIISFLKKKNITYPSLMDETG-----KSFDDYKVRALPMTYVINKN 137

Query: 152 GNVKKIYLGRLKFDELRQDLSQ 173
           G ++    G +  ++LR+ +++
Sbjct: 138 GYLEGFVNGAITDEQLRKAINE 159