BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0340.p (235 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMA2130 [M] COG0744 Membrane carboxypeptidase (penicillin-bindin... 228 1e-59 NMB0357 [M] COG0744 Membrane carboxypeptidase (penicillin-bindin... 226 2e-59 RSc2776 [M] COG0744 Membrane carboxypeptidase (penicillin-bindin... 224 9e-59 CC0325 Non COG 157 2e-38 PM0324 [M] COG0744 Membrane carboxypeptidase (penicillin-binding... 155 7e-38 >NMA2130 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) NmA Neisseria meningitidis Z2491 Length = 233 Score = 228 bits (580), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 107/226 (47%), Positives = 153/226 (67%) Query: 6 KLLFWIVVLPLVLVLLMQLYFFVQIWWWRDHNPESTSFMRQQLALLQEKDPKAQLQFRWV 65 +++ W++ LP+ + + Y + I +R P T+FM ++ +++ L +RW+ Sbjct: 3 RIIKWLIALPVGIFIFFNAYVYGNIITYRAVAPHRTAFMSMRMKQFEQEGRDVALDYRWM 62 Query: 66 PYARISNNLKRAIIASEDSNFSSHDGVDWEALQKAYEKNEKKGKVVAGGSTITQQLAKNL 125 PY RIS NLK+A+IASED+ F+ H G DW +Q A +N GKV AGGSTI+QQLAKNL Sbjct: 63 PYKRISTNLKKALIASEDARFAGHGGFDWGGIQNAIRRNRNSGKVKAGGSTISQQLAKNL 122 Query: 126 FLSGERSYLRKGQEFIITYMLEFLLDKQRIFEIYLNVVEWGNGVFGAEAAAQHYYRIPAA 185 FL+ RSY+RKG+E IT M+E + DK RIFE+YLN +EW GVFGAEAA++++Y+IPAA Sbjct: 123 FLNESRSYIRKGEEAAITAMMEAVTDKDRIFELYLNSIEWHYGVFGAEAASRYFYQIPAA 182 Query: 186 SLGAEQAARLAVMLPRPRYYDRNRGSGYLAARTSLILRRMNAATLP 231 L +QAA+L +P P YY + S L +T+++LRRM +A LP Sbjct: 183 KLTKQQAAKLTARVPAPLYYADHPKSKRLRNKTNIVLRRMGSAELP 228 >NMB0357 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) Nme Neisseria meningitidis MC58 Length = 233 Score = 226 bits (577), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 106/226 (46%), Positives = 153/226 (67%) Query: 6 KLLFWIVVLPLVLVLLMQLYFFVQIWWWRDHNPESTSFMRQQLALLQEKDPKAQLQFRWV 65 +++ W++ LP+ + + Y + I +R P T+FM ++ +++ L +RW+ Sbjct: 3 RIIKWLIALPVGIFIFFNAYVYGNIITYRAVAPHRTAFMSMRMKQFEQEGRDVALDYRWM 62 Query: 66 PYARISNNLKRAIIASEDSNFSSHDGVDWEALQKAYEKNEKKGKVVAGGSTITQQLAKNL 125 PY RIS NLK+A+IASED+ F+ H G DW +Q A +N GKV AGGSTI+QQLAKNL Sbjct: 63 PYKRISTNLKKALIASEDARFAGHGGFDWGGIQNAIRRNRNSGKVKAGGSTISQQLAKNL 122 Query: 126 FLSGERSYLRKGQEFIITYMLEFLLDKQRIFEIYLNVVEWGNGVFGAEAAAQHYYRIPAA 185 FL+ RSY+RKG+E IT M+E + DK RIFE+YLN +EW GVFGAEAA++++Y+IPAA Sbjct: 123 FLNESRSYIRKGEEAAITAMMEAVTDKDRIFELYLNSIEWHYGVFGAEAASRYFYQIPAA 182 Query: 186 SLGAEQAARLAVMLPRPRYYDRNRGSGYLAARTSLILRRMNAATLP 231 L +QAA+L +P P YY + S L +T+++L+RM +A LP Sbjct: 183 KLTKQQAAKLTARVPAPLYYADHPKSKRLRNKTNIVLKRMGSAELP 228 >RSc2776 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) Rso Ralstonia solanacearum Length = 234 Score = 224 bits (572), Expect = 9e-59, Method: Compositional matrix adjust. Identities = 122/218 (55%), Positives = 157/218 (72%), Gaps = 5/218 (2%) Query: 19 VLLMQLYFFVQIWWWRDHNPESTSFMR-QQLALLQEKDPKAQLQFRWVPYARISNNLKRA 77 V+ + LYFF I W+ NP S++FMR +++ L + RWVPY +IS NLKRA Sbjct: 16 VVALNLYFFAAIASWQVFNPASSAFMRAERMRLCGANLVTCGIDHRWVPYDQISRNLKRA 75 Query: 78 IIASEDSNFSSHDGVDWEALQKAYEKNEKKGKVVAGGSTITQQLAKNLFLSGERSYLRKG 137 +IASED++F SH G + +A+ A+EKN+++G VVAGGSTITQQLAKNLFLSGER YLRKG Sbjct: 76 VIASEDADFVSHSGWEVDAMLDAWEKNKRRGHVVAGGSTITQQLAKNLFLSGERHYLRKG 135 Query: 138 QEFIITYMLEFLLDKQRIFEIYLNVVEWGNGVFGAEAAAQHYYRIPAASLGAEQAARLAV 197 +E +IT+MLEF LDK+RI EIYLN VEWG GVFGAEAAAQHY++ PA+ L QAARLA Sbjct: 136 EELVITWMLEFWLDKERILEIYLNSVEWGEGVFGAEAAAQHYFKRPASQLTVGQAARLAA 195 Query: 198 MLPRPRYYDRNRGSGYL----AARTSLILRRMNAATLP 231 LP P+ +D+ R + + ++I RM +ATLP Sbjct: 196 ALPAPKCFDKKRYCANVHISFTRKATVIANRMGSATLP 233 >CC0325 Non COG Length = 229 Score = 157 bits (396), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 82/168 (48%), Positives = 110/168 (65%), Gaps = 1/168 (0%) Query: 60 LQFRWVPYARISNNLKRAIIASEDSNFSSHDGVDWEALQKAYEKNEKKGKVVAGGSTITQ 119 L RW P +IS L R +IA+ED+ F H G D+EALQKAYE NE G+ + GGSTI+Q Sbjct: 52 LDHRWRPMDKISPALPRVLIAAEDAKFCEHRGFDFEALQKAYENNES-GRKIRGGSTISQ 110 Query: 120 QLAKNLFLSGERSYLRKGQEFIITYMLEFLLDKQRIFEIYLNVVEWGNGVFGAEAAAQHY 179 Q AKN+FL RSY+RKG E T ++E K+RI E+Y+N +E+G+G++GAEAAAQ Y Sbjct: 111 QTAKNVFLWPGRSYVRKGLEAWFTVLIETFWGKKRIMEVYMNSIEYGSGIYGAEAAAQRY 170 Query: 180 YRIPAASLGAEQAARLAVMLPRPRYYDRNRGSGYLAARTSLILRRMNA 227 + + AA L Q+ARLA +LP P + + Y+A RT I + A Sbjct: 171 FGVSAAKLTQAQSARLAAILPSPLKWKVIKPGKYVAKRTKKIGKATGA 218 >PM0324 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) Pmu Pasteurella multocida Length = 246 Score = 155 bits (392), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 83/188 (44%), Positives = 123/188 (65%), Gaps = 1/188 (0%) Query: 38 PESTSFMRQQLALLQEKDPKAQLQFRWVPYARISNNLKRAIIASEDSNFSSHDGVDWEAL 97 P S ++Q++ L E + + + ++WVP +IS +++ A+IASED F++H G DW+A+ Sbjct: 48 PFSAYMLQQKIGYLFEGNLSSTIHYQWVPLEQISQSMQLAVIASEDQRFATHYGFDWDAI 107 Query: 98 QKAYEKNEKKGKVVAGGSTITQQLAKNLFLSGERSYLRKGQEFIITYMLEFLLDKQRIFE 157 Q A + N++ GK + GGSTI+QQ AKNL+L +S+LRK E T +LE L K+RI E Sbjct: 108 QSALQHNQR-GKRIRGGSTISQQTAKNLYLWHGQSWLRKAIEMPTTLVLETLWSKKRILE 166 Query: 158 IYLNVVEWGNGVFGAEAAAQHYYRIPAASLGAEQAARLAVMLPRPRYYDRNRGSGYLAAR 217 +YLN+ E+G +FG EAA+QHY+R PA L +AA LA +LP P + N+ S Y+ R Sbjct: 167 VYLNIAEFGPNIFGVEAASQHYFRKPAKQLSNAEAALLAAVLPNPIIFKVNKPSAYVKKR 226 Query: 218 TSLILRRM 225 I R+M Sbjct: 227 QQHIQRQM 234