BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0008.0249.p         (146 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc0455 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolas...   140   1e-33
NMA1818 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolas...   124   1e-28
NMB1619 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolas...   121   5e-28
PA0959 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase...    66   3e-11
CC3657 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase...    62   4e-10

>RSc0455 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other
           HIT family hydrolases Rso Ralstonia solanacearum
          Length = 147

 Score =  140 bits (352), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 71/138 (51%), Positives = 89/138 (64%)

Query: 2   VPACELCAGDGGEVLWQHPVFRVVLVDEADYPGFCRVICHEHVKEMTDLAPAQRTLMANA 61
           V  C LC G+GGE +W++   RVVLV+ A +PGFCRVI + HV E TDL  A R  +   
Sbjct: 7   VAGCALCEGEGGEPVWRNARARVVLVEHARFPGFCRVIWNGHVAEQTDLMEADRRWLMEV 66

Query: 62  VWAVEAALREVMQPEKVNLATLGNMTPHVHWHVIPRFTDDRHFPSPVWAEPRRPADAASI 121
           V  VE   REV+ P+K+NLA+ GN  PH+HWHVIPR+  D HFP  VWA  +R  DAA +
Sbjct: 67  VARVERVQREVLAPDKINLASFGNFVPHLHWHVIPRYRWDTHFPEAVWAAAQREPDAARM 126

Query: 122 AARRARLPQLREAVRRQL 139
           A   ARLP L  A++  L
Sbjct: 127 AEVAARLPALSYALQAAL 144


>NMA1818 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other
           HIT family hydrolases NmA Neisseria meningitidis Z2491
          Length = 134

 Score =  124 bits (310), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 55/111 (49%), Positives = 77/111 (69%), Gaps = 1/111 (0%)

Query: 5   CELCAGDGGEVLWQHPVFRVVLV-DEADYPGFCRVICHEHVKEMTDLAPAQRTLMANAVW 63
           C +C     +VL Q P  RV+ V +++  P FCRVI  +H+ EMTDL+ A+R  +   V+
Sbjct: 6   CPICTAQNEDVLLQTPKLRVIAVHNDSGSPAFCRVIWRKHIAEMTDLSAAERGELMEMVY 65

Query: 64  AVEAALREVMQPEKVNLATLGNMTPHVHWHVIPRFTDDRHFPSPVWAEPRR 114
            VEAA+R+V QP K+NLA+LGN+ PH+HWH+I RF +D  FP+P+WA P R
Sbjct: 66  KVEAAMRQVFQPAKINLASLGNVVPHLHWHIIARFENDASFPAPIWANPVR 116


>NMB1619 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other
           HIT family hydrolases Nme Neisseria meningitidis MC58
          Length = 134

 Score =  121 bits (304), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 54/111 (48%), Positives = 77/111 (69%), Gaps = 1/111 (0%)

Query: 5   CELCAGDGGEVLWQHPVFRVVLV-DEADYPGFCRVICHEHVKEMTDLAPAQRTLMANAVW 63
           C +C     +VL Q P  RV+ V +++  P FCRVI  +H+ EMTDL+ A+R  +   V+
Sbjct: 6   CPICTAQNEDVLLQTPNLRVIAVHNDSGSPAFCRVIWRKHIAEMTDLSAAERGELMEMVY 65

Query: 64  AVEAALREVMQPEKVNLATLGNMTPHVHWHVIPRFTDDRHFPSPVWAEPRR 114
            VEAA+R+V +P K+NLA+LGN+ PH+HWH+I RF +D  FP+P+WA P R
Sbjct: 66  KVEAAMRQVFRPAKINLASLGNVVPHLHWHIIARFENDASFPAPIWANPVR 116


>PA0959 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other
           HIT family hydrolases Pae Pseudomonas aeruginosa
          Length = 209

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 1/115 (0%)

Query: 15  VLWQHPVFRVVLVDEADYPGFCRVICHEHVKEMTDLAPAQRTLMANAVWAVEAALREVMQ 74
           +L   P+ R++L+++A YP F  V   E V E+  L    R  +      +   L++  +
Sbjct: 81  LLGDFPLSRLLLMNDARYPWFILVPRREDVTELFQLDVDDRQALWREATLLAEVLKDTFR 140

Query: 75  PEKVNLATLGNMTPHVHWHVIPRFTDDRHFPSPVWAE-PRRPADAASIAARRARL 128
            +K+N+A LGN+   +H HVI R   D  +P PVW   P RP  +  + A R +L
Sbjct: 141 ADKMNVANLGNVVSQLHMHVIVRRRGDDAWPGPVWGRHPARPYSSEQVEAIRGKL 195


>CC3657 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other
           HIT family hydrolases Ccr Caulobacter vibrioides
          Length = 141

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 40/121 (33%), Positives = 62/121 (51%), Gaps = 7/121 (5%)

Query: 20  PVFRVVLVDEADYPGFCRVICHEHVKEMTDLAPAQRTLMANAVWAVEAALREV-----MQ 74
           P+  V L D+A YP    +     ++E+ DL PA+R  +        +A+R V     ++
Sbjct: 21  PLCEVRLQDDARYPWLVLLPRQPGLRELEDLTPAERAQLMEETIRAGSAVRAVGALLGLR 80

Query: 75  PEKVNLATLGNMTPHVHWHVIPRFTDDRHFPSPVWAEPRRPADAASIAARRARLPQLREA 134
            +K+N+  LGN+T  +H HV+ R  DD  +P PVW     PA A   A R A +   R+A
Sbjct: 81  IDKLNIGALGNVTAQLHVHVVGRRGDDPAWPGPVWGH--SPAQAYDEAVRDAAIATARKA 138

Query: 135 V 135
           +
Sbjct: 139 L 139