BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0241.p (257 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0182 [IQR] COG1028 Dehydrogenases with different specificities... 344 1e-94 SMb20456 [IQR] COG1028 Dehydrogenases with different specificiti... 273 2e-73 mll0534 [IQR] COG1028 Dehydrogenases with different specificitie... 273 4e-73 AGpA258 [IQR] COG1028 Dehydrogenases with different specificitie... 228 8e-60 yjgI [IQR] COG1028 Dehydrogenases with different specificities (... 224 1e-58 >PA0182 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Pae Pseudomonas aeruginosa Length = 250 Score = 344 bits (883), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 185/249 (74%), Positives = 215/249 (86%) Query: 9 AVSPSTLVSKVAFVQGGSRGIGAAIVQRLAAEGATVAFTYVSSPDKAQALVSSVQAKGGR 68 +VS ++L KVAFVQGGSRGIGAAIV+RLAAEGA+VAFTYVSS DK++AL + ++ G Sbjct: 2 SVSSASLAGKVAFVQGGSRGIGAAIVRRLAAEGASVAFTYVSSADKSRALAAELEGAGAS 61 Query: 69 ALAIQADSADAAALQQAIRLAAETFGRLDILVNNAGVLAMGPLDQFKLEDLDRTLAVNVR 128 LA+ ADSADAAAL A+ AA FGR+DILVNNA VLA+G +++ L D +RTLA+NVR Sbjct: 62 ILALHADSADAAALVAAVDEAAARFGRIDILVNNAAVLALGSVEELPLADFERTLAINVR 121 Query: 129 SVFVATQEAARYMGEGGRIISIGSTNADRIPFAGGAVYAMSKSALVGLTKGLARDLGPRG 188 SVFVATQ A ++MG+GGR+ISIGSTNA+R+PFAGGA YAMSKSALVGLTKGLARDLGPRG Sbjct: 122 SVFVATQAAVKHMGDGGRVISIGSTNAERMPFAGGATYAMSKSALVGLTKGLARDLGPRG 181 Query: 189 ITVNNVQPGPVDTDMNPASGDFAASLTGLMALPRYGKAEEIASFVAYLAGPESGYITGAN 248 ITVNNVQPGPVDTDMNP GDFA +L GLMALPRY ++EEIASFVAYLAGPE+ YITGA+ Sbjct: 182 ITVNNVQPGPVDTDMNPDDGDFAEALKGLMALPRYARSEEIASFVAYLAGPEAAYITGAS 241 Query: 249 LMIDGGFSA 257 L IDGGFSA Sbjct: 242 LTIDGGFSA 250 >SMb20456 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 248 Score = 273 bits (699), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 137/244 (56%), Positives = 182/244 (74%) Query: 14 TLVSKVAFVQGGSRGIGAAIVQRLAAEGATVAFTYVSSPDKAQALVSSVQAKGGRALAIQ 73 +L K AFV GGSRGIGAAI +RLA EGA VA TYV++ ++AQA+VS ++ GGRA+AI+ Sbjct: 5 SLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIR 64 Query: 74 ADSADAAALQQAIRLAAETFGRLDILVNNAGVLAMGPLDQFKLEDLDRTLAVNVRSVFVA 133 AD+ DA A++QAIR E G LDILVN+AG+ PL++ + D D +AVN R+ FVA Sbjct: 65 ADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPFVA 124 Query: 134 TQEAARYMGEGGRIISIGSTNADRIPFAGGAVYAMSKSALVGLTKGLARDLGPRGITVNN 193 + A+R++G+GGRII+IGS A+ +P+ G ++Y+ SK+AL GLTKGLARDLGPRGITVN Sbjct: 125 IRSASRHLGDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPRGITVNI 184 Query: 194 VQPGPVDTDMNPASGDFAASLTGLMALPRYGKAEEIASFVAYLAGPESGYITGANLMIDG 253 V PG DTDMNPA GD A + +A YG+ ++IA VA+LAGP+ ++TGA+L IDG Sbjct: 185 VHPGSTDTDMNPADGDHAEAQRERIATGSYGEPQDIAGLVAWLAGPQGKFVTGASLTIDG 244 Query: 254 GFSA 257 G +A Sbjct: 245 GANA 248 >mll0534 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 248 Score = 273 bits (697), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 140/248 (56%), Positives = 179/248 (72%) Query: 10 VSPSTLVSKVAFVQGGSRGIGAAIVQRLAAEGATVAFTYVSSPDKAQALVSSVQAKGGRA 69 +S S L K A V GGSRGIGAAI +RLAA+GA VA TYV ++A+++V+ ++AKGGRA Sbjct: 1 MSSSNLNGKAALVTGGSRGIGAAIARRLAADGADVALTYVHGEEQARSVVAEIEAKGGRA 60 Query: 70 LAIQADSADAAALQQAIRLAAETFGRLDILVNNAGVLAMGPLDQFKLEDLDRTLAVNVRS 129 +AI+AD+ DA A+ +A+ A FGRLDILVN+AG+ P+D L D D T++VN+R+ Sbjct: 61 IAIRADNRDAEAIDRAVDETAAAFGRLDILVNSAGIWRAAPIDTLSLADFDETMSVNLRA 120 Query: 130 VFVATQEAARYMGEGGRIISIGSTNADRIPFAGGAVYAMSKSALVGLTKGLARDLGPRGI 189 F+A++ AA +MGEGGRIISIGS A+R+ Y+ SK+ALVGLTK LARDLG RGI Sbjct: 121 PFIASKAAAAHMGEGGRIISIGSNLAERVTDTNLGAYSASKAALVGLTKALARDLGSRGI 180 Query: 190 TVNNVQPGPVDTDMNPASGDFAASLTGLMALPRYGKAEEIASFVAYLAGPESGYITGANL 249 T N V PG DTDMNPA G A MA PR+GKA++IA VA+LAGPE ++TGA L Sbjct: 181 TANVVHPGSTDTDMNPADGPHAEHQRQKMATPRFGKADDIAGMVAWLAGPEGRFVTGAAL 240 Query: 250 MIDGGFSA 257 IDGG +A Sbjct: 241 TIDGGANA 248 >AGpA258 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 269 Score = 228 bits (582), Expect = 8e-60, Method: Compositional matrix adjust. Identities = 129/243 (53%), Positives = 166/243 (68%) Query: 15 LVSKVAFVQGGSRGIGAAIVQRLAAEGATVAFTYVSSPDKAQALVSSVQAKGGRALAIQA 74 L K+A V GGSR IGA+I QRLAA+GA VAFTY SP KA+ + +++ G RALAI A Sbjct: 27 LNGKIALVTGGSRSIGASIAQRLAADGAQVAFTYRGSPAKAEEVAVAIEKTGARALAIAA 86 Query: 75 DSADAAALQQAIRLAAETFGRLDILVNNAGVLAMGPLDQFKLEDLDRTLAVNVRSVFVAT 134 D+AD A++ A+ + FG LDILVNNAG+ GP+D+ +D LA+NV VFVAT Sbjct: 87 DAADPDAIRAAVAATVDKFGGLDILVNNAGIAFAGPIDEIAFDDYQAMLAINVTGVFVAT 146 Query: 135 QEAARYMGEGGRIISIGSTNADRIPFAGGAVYAMSKSALVGLTKGLARDLGPRGITVNNV 194 QEA R+M +GGRII IGS+ G + Y ++K A+ G + LA DLGPRGITVN V Sbjct: 147 QEAVRHMKDGGRIIHIGSSITKYAGVPGLSAYGLTKGAVAGFNRSLAHDLGPRGITVNTV 206 Query: 195 QPGPVDTDMNPASGDFAASLTGLMALPRYGKAEEIASFVAYLAGPESGYITGANLMIDGG 254 PGP DTDMNP G+FAA +A RYGK EIA+ VA+LA PE+ ++TGA++ DGG Sbjct: 207 HPGPTDTDMNPVDGEFAAMQISRIAAGRYGKPREIANVVAFLASPEASFVTGADIRADGG 266 Query: 255 FSA 257 F++ Sbjct: 267 FTS 269 >yjgI [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Eco Escherichia coli K12 Length = 237 Score = 224 bits (572), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 124/243 (51%), Positives = 156/243 (64%), Gaps = 9/243 (3%) Query: 15 LVSKVAFVQGGSRGIGAAIVQRLAAEGATVAFTYVSSPDKAQALVSSVQAKGGRALAIQA 74 K + GGSRGIGAAIV+R +GA V FTY S D A+ L Q G A A+ Sbjct: 4 FTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLA---QETG--ATAVFT 58 Query: 75 DSADAAALQQAIRLAAETFGRLDILVNNAGVLAMGPLDQFKLEDLDRTLAVNVRSVFVAT 134 DSAD A+ +R + G LDILV NAG+ G + +D+DR +N+ + + A+ Sbjct: 59 DSADRDAVIDVVRKS----GALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHAS 114 Query: 135 QEAARYMGEGGRIISIGSTNADRIPFAGGAVYAMSKSALVGLTKGLARDLGPRGITVNNV 194 EAAR M EGGRI+ IGS N DR+P AG A YA SKSAL G+ +GLARD GPRGIT+N V Sbjct: 115 VEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVV 174 Query: 195 QPGPVDTDMNPASGDFAASLTGLMALPRYGKAEEIASFVAYLAGPESGYITGANLMIDGG 254 QPGP+DTD NPA+G L LMA+ R+G+ EE+A VA+LAGPE+ ++TGA IDG Sbjct: 175 QPGPIDTDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGA 234 Query: 255 FSA 257 F A Sbjct: 235 FGA 237