BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0237.p (502 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2881 [EH] COG0147 Anthranilate/para-aminobenzoate synthases c... 784 0.0 NMA1247 [EH] COG0147 Anthranilate/para-aminobenzoate synthases c... 601 e-171 NMB1021 [EH] COG0147 Anthranilate/para-aminobenzoate synthases c... 600 e-171 PA0609 [EH] COG0147 Anthranilate/para-aminobenzoate synthases co... 510 e-144 XF0210 [EH] COG0147 Anthranilate/para-aminobenzoate synthases co... 476 e-134 >RSc2881 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I Rso Ralstonia solanacearum Length = 509 Score = 784 bits (2024), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/513 (75%), Positives = 436/513 (84%), Gaps = 15/513 (2%) Query: 1 MTELEFKSLATEGYNRIPLIAEAFADLETPLTLYLKLAQSHHTGKNTFLLESVVGGERFG 60 MTELEFKSLA +GYNRIPLIAEA ADLETPL+LYLKLAQSH G +TFLLESVVGGERFG Sbjct: 1 MTELEFKSLADQGYNRIPLIAEALADLETPLSLYLKLAQSHDRGTHTFLLESVVGGERFG 60 Query: 61 RYSFIGLPASTKIRCSGKQIEVLKNDVVIETAEGNALEFIAQYQSRFKVAIRPGMPRFCG 120 RYSFIGL A T +R +G + EV+ + V+ET +GN LEFIA ++ R K+A+RPG+PRFCG Sbjct: 61 RYSFIGLHARTLLRTTGHRTEVVTDGQVVETHDGNPLEFIAAFEQRHKIALRPGLPRFCG 120 Query: 121 GLAGYFGYDAVRYIEKRLEDSAPKDTLGLPDIQLLLTEELAVIDNLSGKLYLIVYADPTQ 180 GLAGYFGYDAVRYIE RL D+AP D L LPDIQL+L EELAVIDNLSGKLYLIVYADP++ Sbjct: 121 GLAGYFGYDAVRYIEPRLTDTAPPDDLQLPDIQLMLCEELAVIDNLSGKLYLIVYADPSK 180 Query: 181 PEAFSRGRQRLRDLRAMLRRPADAPVTTGSVRTETIREFPKDEYLKAVARAKEYVMAGDL 240 PEA+ R RQRLR+LRA LR P D PVT+ SVRT+ +REF K +Y+ AV +AKEY+ AGD+ Sbjct: 181 PEAYPRARQRLRELRAKLRHPVDVPVTSPSVRTDIVREFDKADYITAVLKAKEYIAAGDM 240 Query: 241 MQVQIGQRLKKSYVDSPLMLYRALRSLNPSPYMYFYNFGDMQIVGASPEILVRNE----- 295 MQVQ+GQRL K + D+PL LYRALRSLNPSPYMYFYNFGDMQIVGASPEILVR E Sbjct: 241 MQVQVGQRLVKPFRDAPLSLYRALRSLNPSPYMYFYNFGDMQIVGASPEILVRQEERRVP 300 Query: 296 --SIGEGQKK----ITIRPLAGTRPRGSTIERDEQLARELLADPKEIAEHVMLIDLARND 349 + G G ++ +TIRPLAGTRPRGST ERD +LA ELL DPKEIAEHVMLIDLARND Sbjct: 301 AGANGNGAEESARIVTIRPLAGTRPRGSTPERDAELATELLNDPKEIAEHVMLIDLARND 360 Query: 350 IGRIATTGSVKVTDQMVIEKYSHVQHIVSNVEGILKPGMSNLDVLKATFPAGTLSGAPKV 409 IGRIA GSVKVTDQMVIEKYSHVQHIVS+VEG LKPGM+N+DVL+ATFPAGTLSGA Sbjct: 361 IGRIAEIGSVKVTDQMVIEKYSHVQHIVSSVEGRLKPGMTNMDVLRATFPAGTLSGA--- 417 Query: 410 RPKVRAMEIIDELEPTKRGIYGGACGYLSFGGEMDVAIAIRTGVIKDGTLYVQAAAGIVA 469 PKVRAMEIIDELEP KRGIYGGA GYLSF GEMD+AIAIRTG+IKDG LYVQAAAG+VA Sbjct: 418 -PKVRAMEIIDELEPVKRGIYGGAVGYLSFSGEMDLAIAIRTGIIKDGNLYVQAAAGVVA 476 Query: 470 DSVPEMEWEETENKARAVLRAAEQVQDGLDGEI 502 DS P+ EW ETE+KARAVLRAAEQVQDGLD + Sbjct: 477 DSDPDAEWRETEHKARAVLRAAEQVQDGLDADF 509 >NMA1247 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I NmA Neisseria meningitidis Z2491 Length = 491 Score = 601 bits (1550), Expect = e-171, Method: Compositional matrix adjust. Identities = 292/502 (58%), Positives = 376/502 (74%), Gaps = 16/502 (3%) Query: 1 MTELEFKSLATEGYNRIPLIAEAFADLETPLTLYLKLAQSHHTGKNTFLLESVVGGERFG 60 +++ E+++ A +GYNRIPL+ E ADL+TPL+LYLKLA +T +LLESVVGGERFG Sbjct: 2 ISKQEYQAQAAQGYNRIPLVQELLADLDTPLSLYLKLANRPYT----YLLESVVGGERFG 57 Query: 61 RYSFIGLPASTKIRCSGKQIEVLKNDVVIETAEGNALEFIAQYQSRFKVAIRPGMPRFCG 120 RYSFIGLP S ++ SGK ++V +N ++E +GN L FI + +RFK P +PRF G Sbjct: 58 RYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHDGNPLPFIEAFHNRFKTPEIPSLPRFTG 117 Query: 121 GLAGYFGYDAVRYIEK---RLEDSAPKDTLGLPDIQLLLTEELAVIDNLSGKLYLIVYAD 177 GL GYFGY+ + E RL+++ D LG PDI L+L++ELAVIDNLSGK++L+VYAD Sbjct: 118 GLVGYFGYETIYNFEHFAHRLKNTTKADPLGTPDILLMLSQELAVIDNLSGKIHLVVYAD 177 Query: 178 PTQPEAFSRGRQRLRDLRAMLRRPADAPVTTGSVRTETIREFPKDEYLKAVARAKEYVMA 237 P+QP+ + R R+RL D+R LR+ P++ GS TE + EF ++ + V + K+Y+ A Sbjct: 178 PSQPDGYERARERLEDIRTQLRQSCAIPLSLGSKHTEAVSEFGEEPFKACVNKIKDYIFA 237 Query: 238 GDLMQVQIGQRLKKSYVDSPLMLYRALRSLNPSPYMYFYNFGDMQIVGASPEILVRNESI 297 GD MQV QR+ + DSPL LYRALR+LNPSPY+++Y+FGD IVG+SPEILVR E Sbjct: 238 GDCMQVVPSQRMSMEFTDSPLALYRALRTLNPSPYLFYYDFGDFHIVGSSPEILVRRE-- 295 Query: 298 GEGQKKITIRPLAGTRPRGSTIERDEQLARELLADPKEIAEHVMLIDLARNDIGRIATTG 357 + + +RP+AGTR RG T D ++LL+D KEIAEHVMLIDL RND+GRI+ TG Sbjct: 296 ---RDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKEIAEHVMLIDLGRNDVGRISKTG 352 Query: 358 SVKVTDQMVIEKYSHVQHIVSNVEGILKPGMSNLDVLKATFPAGTLSGAPKVRPKVRAME 417 VKVTD+MVIEKYSHV HIVSNVEG LK GM+N+D+L ATFPAGTLSGA PKVRAME Sbjct: 353 EVKVTDKMVIEKYSHVMHIVSNVEGRLKDGMTNMDILAATFPAGTLSGA----PKVRAME 408 Query: 418 IIDELEPTKRGIYGGACGYLSFGGEMDVAIAIRTGVIKDGTLYVQAAAGIVADSVPEMEW 477 II+E+EP+KRGIYGGA G F +MD+AIAIRT V+K+ TLYVQ+ AG+VADS P EW Sbjct: 409 IIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTLYVQSGAGVVADSDPASEW 468 Query: 478 EETENKARAVLRAAEQVQDGLD 499 +ET+NKARAV+RAA+ VQ+GLD Sbjct: 469 QETQNKARAVIRAAQMVQEGLD 490 >NMB1021 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I Nme Neisseria meningitidis MC58 Length = 491 Score = 600 bits (1546), Expect = e-171, Method: Compositional matrix adjust. Identities = 291/502 (57%), Positives = 375/502 (74%), Gaps = 16/502 (3%) Query: 1 MTELEFKSLATEGYNRIPLIAEAFADLETPLTLYLKLAQSHHTGKNTFLLESVVGGERFG 60 +++ E+++ A +GYNRIPL+ E ADL+TPL+LYLKLA +T +LLESVVGGERFG Sbjct: 2 ISKQEYQAQAAQGYNRIPLVQELLADLDTPLSLYLKLANRPYT----YLLESVVGGERFG 57 Query: 61 RYSFIGLPASTKIRCSGKQIEVLKNDVVIETAEGNALEFIAQYQSRFKVAIRPGMPRFCG 120 RYSFIGLP S ++ SGK ++V +N ++E +GN L FI + +RFK P +PRF G Sbjct: 58 RYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHDGNPLPFIEAFHNRFKTPEIPSLPRFTG 117 Query: 121 GLAGYFGYDAVRYIEK---RLEDSAPKDTLGLPDIQLLLTEELAVIDNLSGKLYLIVYAD 177 GL GYFGY+ + E RL+++ D LG PDI L+L++ELAVIDNLSGK++L+VYAD Sbjct: 118 GLVGYFGYETIYNFEHFAHRLKNTTKADPLGTPDILLMLSQELAVIDNLSGKIHLVVYAD 177 Query: 178 PTQPEAFSRGRQRLRDLRAMLRRPADAPVTTGSVRTETIREFPKDEYLKAVARAKEYVMA 237 P+QP+ + R R+RL D+R LR+ P++ GS TE + EF ++ + V + K+Y+ A Sbjct: 178 PSQPDGYERARERLEDIRTQLRQSCAIPLSLGSKHTEAVSEFGEEPFKACVNKIKDYIFA 237 Query: 238 GDLMQVQIGQRLKKSYVDSPLMLYRALRSLNPSPYMYFYNFGDMQIVGASPEILVRNESI 297 GD MQV QR+ + DSPL LYRALR+LNPSPY+++Y+FGD IVG+SPEILVR E Sbjct: 238 GDCMQVVPSQRMSMEFTDSPLALYRALRTLNPSPYLFYYDFGDFHIVGSSPEILVRRE-- 295 Query: 298 GEGQKKITIRPLAGTRPRGSTIERDEQLARELLADPKEIAEHVMLIDLARNDIGRIATTG 357 + + +RP+AGTR RG T D ++LL+D KEIAEHVMLIDL RND+GRI+ TG Sbjct: 296 ---RNDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKEIAEHVMLIDLGRNDVGRISKTG 352 Query: 358 SVKVTDQMVIEKYSHVQHIVSNVEGILKPGMSNLDVLKATFPAGTLSGAPKVRPKVRAME 417 VKVTD+MVIEKYSHV HIVSNVEG LK GM+N+D+L ATFPAGTLSGA PKVRAME Sbjct: 353 EVKVTDKMVIEKYSHVMHIVSNVEGRLKDGMTNMDILAATFPAGTLSGA----PKVRAME 408 Query: 418 IIDELEPTKRGIYGGACGYLSFGGEMDVAIAIRTGVIKDGTLYVQAAAGIVADSVPEMEW 477 II+E+EP+KRGIYGGA G F +MD+AIAIRT V+K+ TLYVQ+ AG+VADS P EW Sbjct: 409 IIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTLYVQSGAGVVADSDPASEW 468 Query: 478 EETENKARAVLRAAEQVQDGLD 499 +ET+NKARAV+ AA+ VQ+GLD Sbjct: 469 QETQNKARAVIHAAQMVQEGLD 490 >PA0609 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I Pae Pseudomonas aeruginosa Length = 492 Score = 510 bits (1313), Expect = e-144, Method: Compositional matrix adjust. Identities = 270/504 (53%), Positives = 349/504 (69%), Gaps = 26/504 (5%) Query: 1 MTELEFKSLATEGYNRIPLIAEAFADLETPLTLYLKLAQSHHTGKNTFLLESVVGGERFG 60 M EF LA +GYNRIPL E AD +TPL++YLKLA + N++LLESV GGE++G Sbjct: 1 MNREEFLRLAADGYNRIPLSFETLADFDTPLSIYLKLADA----PNSYLLESVQGGEKWG 56 Query: 61 RYSFIGLPASTKIRCSGKQIEVLKNDVVIETAE-GNALEFIAQYQSRFKVAIRPGMPRFC 119 RYS IGLP T +R Q+ + + V E + + L F+ ++++R++V PG+PRF Sbjct: 57 RYSIIGLPCRTVLRVYDHQVRISIDGVETERFDCADPLAFVEEFKARYQVPTVPGLPRFD 116 Query: 120 GGLAGYFGYDAVRYIEKRLEDSAPKDTLGLPDIQLLLTEELAVIDNLSGKLYLIVYADPT 179 GGL GYFGYD VRY+EKRL D LG PDI L++++ + V DNL+GK++ IV ADP+ Sbjct: 117 GGLVGYFGYDCVRYVEKRLATCPNPDPLGNPDILLMVSDAVVVFDNLAGKIHAIVLADPS 176 Query: 180 QPEAFSRGRQRLRDLRAML------RRPADAPVTTGSVRTETIR-EFPKDEYLKAVARAK 232 + A+ RG+ RL +L L RR D G R R F +++Y AV R K Sbjct: 177 EENAYERGQARLEELLERLRQPITPRRGLDLEAAQG--REPAFRASFTREDYENAVGRIK 234 Query: 233 EYVMAGDLMQVQIGQRLKKSYVDSPLMLYRALRSLNPSPYMYFYNFGDMQIVGASPEILV 292 +Y++AGD MQV QR+ + +P+ LYRALR NP+PYMYF+NFGD +VG+SPE+LV Sbjct: 235 DYILAGDCMQVVPSQRMSIEFKAAPIDLYRALRCFNPTPYMYFFNFGDFHVVGSSPEVLV 294 Query: 293 RNESIGEGQKKITIRPLAGTRPRGSTIERDEQLARELLADPKEIAEHVMLIDLARNDIGR 352 R E +T+RP+AGTRPRG E D L ++LL+D KEIAEH+MLIDL RND+GR Sbjct: 295 RVED-----GLVTVRPIAGTRPRGINEEADLALEQDLLSDAKEIAEHLMLIDLGRNDVGR 349 Query: 353 IATTGSVKVTDQMVIEKYSHVQHIVSNVEGILKPGMSNLDVLKATFPAGTLSGAPKVRPK 412 ++ G+VKVT++MVIE+YS+V HIVSNV G L+ G+S +D L+A PAGTLSGA PK Sbjct: 350 VSDIGAVKVTEKMVIERYSNVMHIVSNVTGQLREGLSAMDALRAILPAGTLSGA----PK 405 Query: 413 VRAMEIIDELEPTKRGIYGGACGYLSFGGEMDVAIAIRTGVIKDGTLYVQAAAGIVADSV 472 +RAMEIIDELEP KRG+YGGA GYL++ G MD AIAIRT VIK+G L+VQA GIVADSV Sbjct: 406 IRAMEIIDELEPVKRGVYGGAVGYLAWNGNMDTAIAIRTAVIKNGELHVQAGGGIVADSV 465 Query: 473 PEMEWEETENKARAVLRA---AEQ 493 P +EWEET NK RA+ RA AEQ Sbjct: 466 PALEWEETINKRRAMFRAVALAEQ 489 >XF0210 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I Xfa Xylella fastidiosa 9a5c Length = 487 Score = 476 bits (1225), Expect = e-134, Method: Compositional matrix adjust. Identities = 254/503 (50%), Positives = 337/503 (66%), Gaps = 24/503 (4%) Query: 4 LEFKSLATEGYNRIPLIAEAFADLETPLTLYLKLAQSHHTGKNTFLLESVVGGERFGRYS 63 ++F+ EG RIP++ E +DL+TPL++YLK A + +T +L ESV GGE F RYS Sbjct: 1 MQFQRQVAEGCTRIPVVREVQSDLDTPLSVYLKFADAPYT----YLFESVEGGEHFARYS 56 Query: 64 FIGLPASTKIRCSGKQIEVLKNDVVIETAE-GNALEFIAQYQSRFKVAIRPGMPRFCGGL 122 IGLPA G + V + V+ET + + L + ++++ V G+P F GGL Sbjct: 57 IIGLPARRVYTFHGHTLVVSEFGKVLETRQVADPLAEVELLRAQYVVPQLEGLPGFTGGL 116 Query: 123 AGYFGYDAVRYIEKRLEDSAPKDTLGLPDIQLLLTEELAVIDNLSGKLYLIVYADPTQPE 182 G+FG++ ++YIE R + +D LG PDI L+L+EELAV D+L G+LYLIV+ADP QP Sbjct: 117 VGWFGFECIQYIEPRFMEGKKRDELGTPDILLMLSEELAVFDSLKGRLYLIVHADPAQPH 176 Query: 183 AFSRGRQRLRDLRAMLRRPA-DAPVTTGSVRTETIRE------FPKDEYLKAVARAKEYV 235 A++R +RL L LR+ D P S +E I E +++Y V +A+EYV Sbjct: 177 AYARAVERLDVLIYRLRQGGVDYP---HSHISEVINEEDFHSSLTREQYHAVVRQAQEYV 233 Query: 236 MAGDLMQVQIGQRLKKSYVDSPLMLYRALRSLNPSPYMYFYNFGDMQIVGASPEILVRNE 295 +GD+ QV QRL + P+ +YRALR+LNPSPYMYF + G Q+VG+SPEIL R + Sbjct: 234 RSGDIFQVVPSQRLCTQFHARPIDVYRALRTLNPSPYMYFIDIGATQVVGSSPEILARLQ 293 Query: 296 SIGEGQKKITIRPLAGTRPRGSTIERDEQLARELLADPKEIAEHVMLIDLARNDIGRIAT 355 +T+RP+AGTRPRG+T E D++L ELLADPKE AEHVMLIDL RNDIGR+ Sbjct: 294 G-----DVVTVRPIAGTRPRGATPEHDKRLEMELLADPKERAEHVMLIDLGRNDIGRVVE 348 Query: 356 TGSVKVTDQMVIEKYSHVQHIVSNVEGILKPGMSNLDVLKATFPAGTLSGAPKVRPKVRA 415 GSV+V + VIE+YSHV HIVS V GILKPG++ +DVL+ATFPAGT+SGA PK+RA Sbjct: 349 AGSVQVKESFVIERYSHVMHIVSEVTGILKPGLNYVDVLRATFPAGTVSGA----PKIRA 404 Query: 416 MEIIDELEPTKRGIYGGACGYLSFGGEMDVAIAIRTGVIKDGTLYVQAAAGIVADSVPEM 475 +EII ELEP R +Y GA GY+ + G+ D AIAIRT VI++G LYVQA G+V DS P++ Sbjct: 405 LEIIRELEPVCRNVYSGAVGYIGWHGDADTAIAIRTAVIQNGCLYVQAGGGVVYDSDPDL 464 Query: 476 EWEETENKARAVLRAAEQVQDGL 498 EW+ET NKARA+ RA Q GL Sbjct: 465 EWQETMNKARALFRAVAQAARGL 487