BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0008.0229.p         (148 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

VC0262 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Vch ...   181   5e-46
PA3146 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Pae ...   111   5e-25
BMEI1237 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Bm...    96   3e-20
BH3715 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Bha ...    81   8e-16
FN1694 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Fnu ...    79   4e-15

>VC0262 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Vch Vibrio
           cholerae
          Length = 323

 Score =  181 bits (459), Expect = 5e-46,   Method: Compositional matrix adjust.
 Identities = 91/144 (63%), Positives = 107/144 (74%), Gaps = 1/144 (0%)

Query: 1   MNETASDPLAEFRRVNLEGSLALARQAQQAGVQRFIFLSSIKVNGEQTSLGRPFTADDKP 60
           M ET +D L  +R VN +G+L LA+QA  AGV+RFIFLSSIKVNGEQT  G  F  DD+ 
Sbjct: 80  MQETEADALKAYRDVNTQGTLNLAKQAVSAGVKRFIFLSSIKVNGEQTKAGSAFQHDDQH 139

Query: 61  APTDPYGISKMEAEQALLELGRTGKMQVVIIRPVLVYGPGVKANFLSMMRWLDKGMPLPL 120
            P+DPYG+SK EAEQ LLEL     ++VVIIRP LVYG GVKANFLSMM W+ K +PLPL
Sbjct: 140 IPSDPYGLSKYEAEQQLLELAAETGLEVVIIRPPLVYGEGVKANFLSMMNWVKKQIPLPL 199

Query: 121 GGITHNRRSLVALDNLVDLIIIII 144
           G +  N RSLV LDNLVDLI++  
Sbjct: 200 GAVG-NMRSLVYLDNLVDLILVCC 222


>PA3146 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Pae
           Pseudomonas aeruginosa
          Length = 316

 Score =  111 bits (278), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 60/143 (41%), Positives = 87/143 (60%), Gaps = 2/143 (1%)

Query: 1   MNETASDPLAEFRRVNLEGSLALARQAQQAGVQRFIFLSSIKVNGEQTSLGRPFTADDKP 60
           + +  +DPLA FR VN + ++ LA +A +AGV+RF+F+SSI VNG  T   + F  D   
Sbjct: 71  LTDKVADPLAAFREVNRDATVRLATRALEAGVKRFVFVSSIGVNGNSTRQ-QAFNEDSPA 129

Query: 61  APTDPYGISKMEAEQALLELGRTGKMQVVIIRPVLVYGPGVKANFLSMMRWLDKGMPLPL 120
            P  PY ISK EAEQ L  L R   M++V++RP L+Y      NF  +++ +  G+PLPL
Sbjct: 130 GPHAPYAISKYEAEQELGTLLRGKGMELVVVRPPLIYANDAPGNFGRLLKLVASGLPLPL 189

Query: 121 GGITHNRRSLVALDNLVDLIIII 143
            G+  N RSLV+  N+V  + + 
Sbjct: 190 DGV-RNARSLVSRRNIVGFLSLC 211


>BMEI1237 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Bme Brucella
           melitensis
          Length = 289

 Score = 95.9 bits (237), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 56/132 (42%), Positives = 80/132 (60%), Gaps = 7/132 (5%)

Query: 12  FRRVNLEGSLALARQAQQAGVQRFIFLSSIKVNGEQTSLGRPFTADDKPAPTDPYGISKM 71
           F  VN   ++ LAR+A+  GV+RF+F+S+I       S   P   D   AP D YG +K 
Sbjct: 66  FDAVNHRLAVELARKAKAQGVRRFVFVSTIYTIAGNPS---PLAPDMPLAPRDDYGRAKA 122

Query: 72  EAEQALLELGRTGKMQVVIIRPVLVYGPGVKANFLSMMRWLDKGMPLPLGGITHNRRSLV 131
            AE ALL +  TG + +VI RPVLVYGPG +AN  ++M+  D  +PLP G   +N+RS V
Sbjct: 123 RAEAALLAM--TG-LDIVIARPVLVYGPGARANLKALMKLCDSRIPLPFGA-ANNKRSFV 178

Query: 132 ALDNLVDLIIII 143
           +L+N+   +I +
Sbjct: 179 SLENVARALIFL 190


>BH3715 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Bha Bacillus
           halodurans
          Length = 282

 Score = 81.3 bits (199), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 45/133 (33%), Positives = 78/133 (58%), Gaps = 7/133 (5%)

Query: 12  FRRVNLEGSLALARQAQQAGVQRFIFLSSIKVNGEQTSLGRPFTADDKPAPTDPYGISKM 71
           + +VN + +   A++A+  G+++FIFLSS+ V G++  +      D  P PT  YG SK+
Sbjct: 70  YFKVNRDVAYEAAKKAKDEGIKQFIFLSSMSVYGKENGI---IDLDTLPKPTSNYGESKL 126

Query: 72  EAEQALLELGRTGKMQVVIIRPVLVYGPGVKANFLSMMRWLDKGMPLPLGGITHNRRSLV 131
           +AE+ L+E+      +VV IRP ++YG G K N+  + +   K   LP+     N RS++
Sbjct: 127 QAEK-LIEMLDDDSFKVVTIRPPMIYGKGCKGNYPKLAKLARK---LPVFPDVENERSMI 182

Query: 132 ALDNLVDLIIIII 144
            ++NL + + +II
Sbjct: 183 HIENLCEFMKLII 195


>FN1694 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Fnu
           Fusobacterium nucleatum
          Length = 290

 Score = 79.0 bits (193), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 50/138 (36%), Positives = 77/138 (55%), Gaps = 6/138 (4%)

Query: 11  EFRRVNLEGSLALARQAQQAGVQRFIFLSSIKVNGEQTSLGRPFTADDKPAPT----DPY 66
           ++  VN E +  +A +A+  GV+ F+F S++KV G    L       ++ +      DPY
Sbjct: 67  KYFEVNTELTRRIAEKAKIEGVKHFVFYSTVKVYGYDGDLKNHNYVLNELSECNPKNDPY 126

Query: 67  GISKMEAEQALLELGRTGKMQVVIIRPVLVYGPGVKANFLSMMRWLDKGMPLPLGGITHN 126
           G SK EAE+ L +L      +V IIRP +VYG GVK N  S+++ + K   LP      N
Sbjct: 127 GESKWEAEKILKKL-ENDNFRVAIIRPPMVYGKGVKGNMESLIKLIKKSPILPF-KYDKN 184

Query: 127 RRSLVALDNLVDLIIIII 144
           +RSLV ++NL+ L  ++I
Sbjct: 185 KRSLVNINNLLYLTYLVI 202