BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0151.p (302 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_alsR [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis 183 3e-46 BMEII0820 [K] COG0583 Transcriptional regulator Bme Brucella mel... 180 3e-45 PA5029 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 176 7e-44 STM3121 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 176 8e-44 CC3045 Non COG 172 1e-42 >BS_alsR [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis Length = 302 Score = 183 bits (465), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 103/288 (35%), Positives = 159/288 (55%), Gaps = 9/288 (3%) Query: 2 IELRHLTYFRTVAETLHFGRAAELLHISQPPLTRQIAALEKELGAQLFDRSKRAIQLTAA 61 +ELRHL YF VAE LHFG+AA L+++QPPL++QI LE+E+G L R+KR ++LTAA Sbjct: 1 MELRHLQYFIAVAEELHFGKAARRLNMTQPPLSQQIKQLEEEVGVTLLKRTKRFVELTAA 60 Query: 62 GKYFYRDT----TEIFKALERAKRNVSSSSTGKSGALKVGFMMSTAYNILPSVTRHYSAA 117 G+ F +I + +E A+R ++ G+ G L +GF+ S Y LP + R Y Sbjct: 61 GEIFLNHCRMALMQIGQGIELAQR----TARGEQGLLVIGFVGSATYEFLPPIVREYRKK 116 Query: 118 YPEVDMRLTEYVPNLLATDIEDEKIDVGIMYRPEDCRRLDSHTIYAEPLLAVLPRDHRLA 177 +P V + L E + ++ ID+GI++ P L T + P + LP+ H L Sbjct: 117 FPSVKIELREISSSRQQEELLKGNIDIGILHPPLQHTALHIETAQSSPCVLALPKQHPLT 176 Query: 178 GRQSISAAELAEDAFISIPRMIAPVVYDLIQQHCQLHGFRPRIVLETNLQQTIVNLVGEG 237 ++SI+ +L ++ I++ + P +Y Q C+ GFRP IV E Q ++ LV G Sbjct: 177 SKESITIEDLRDEPIITVAKEAWPTLYMDFIQFCEQAGFRPNIVQEATEYQMVIGLVSAG 236 Query: 238 LGVALVPTSMQAM-HLDTTVFKPLIGAPMVEVAVIWNKDNTNPCIRTF 284 +G+ VP+S + + +LD T K E + + KDN NP I+ F Sbjct: 237 IGMTFVPSSAKKLFNLDVTYRKMDQIQLNAEWVIAYRKDNHNPLIKHF 284 >BMEII0820 [K] COG0583 Transcriptional regulator Bme Brucella melitensis Length = 299 Score = 180 bits (457), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 102/268 (38%), Positives = 151/268 (56%), Gaps = 4/268 (1%) Query: 2 IELRHLTYFRTVAETLHFGRAAELLHISQPPLTRQIAALEKELGAQLFDRSKRAIQLTAA 61 +ELRHL YF VAE +F RAA L I QPPL++QI LE E+G LF R +LTAA Sbjct: 5 MELRHLRYFLAVAEEGNFTRAAAKLGIGQPPLSQQIRDLENEIGVMLFHRVPHGAELTAA 64 Query: 62 GKYFYRDTTEIFKALERAKRNVSSSSTGKSGALKVGFMMSTAYN-ILPSVTRHYSAAYPE 120 G F + T + E+AK ++ G+SG L +GF S+A+N I+ RH+ A +PE Sbjct: 65 GAAFLEEATATIASSEKAKLAAQRAARGESGRLSLGFTASSAFNPIVSGAIRHFRAKWPE 124 Query: 121 VDMRLTEYVPNLLATDIEDEKIDVGIMYRP--EDCRRLDSHTIYAEPLLAVLPRDHRLAG 178 V++ LTE NLL + ++D + RP ED + + EP+L LP HRLA Sbjct: 125 VELFLTEMNTNLLIERLVRGELDTAFI-RPGLEDPANVRMKRLADEPMLVALPSHHRLAV 183 Query: 179 RQSISAAELAEDAFISIPRMIAPVVYDLIQQHCQLHGFRPRIVLETNLQQTIVNLVGEGL 238 + + + LA + F+ PR++ +YD I C++ GF + E ++VNLV L Sbjct: 184 YERLPLSALAGEPFVLFPRIVGLSLYDDIAAACRMAGFEMNVTQEAPQMPSVVNLVAANL 243 Query: 239 GVALVPTSMQAMHLDTTVFKPLIGAPMV 266 GV++VP ++ + LD ++P+ G P+V Sbjct: 244 GVSIVPAAIAQIRLDGVTYRPIEGEPLV 271 >PA5029 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 301 Score = 176 bits (445), Expect = 7e-44, Method: Compositional matrix adjust. Identities = 106/293 (36%), Positives = 166/293 (56%), Gaps = 12/293 (4%) Query: 2 IELRHLTYFRTVAETLHFGRAAELLHISQPPLTRQIAALEKELGAQLFDRSKRAIQLTAA 61 +ELRHL YF VAE LHFGRAAE L ISQPPL++QI ALE+E+GA+LF+R+ R ++LT A Sbjct: 1 MELRHLRYFIAVAEELHFGRAAERLGISQPPLSQQIQALEEEIGARLFERTNRRVELTDA 60 Query: 62 GKYFYRDTTEIFKALERAKRNVSSSSTGKSGALKVGFMMSTAY-NILPSVTRHYSAAYPE 120 G+ F ++ ++ +++A + G+ G LK+GF S + + +PS + AYP+ Sbjct: 61 GRLFLDESRQVLAQVDKAVLLARRAHLGELGELKIGFTSSAPFTSTIPSSIHAFRKAYPD 120 Query: 121 VDMRLTEYVPNLLATDIEDEKIDVGI---MYRPEDCRRLDSHTIYAEPLLAVLPRDHRLA 177 V + L E + + +E + VG+ + P+ ++ ++ EPL+AVL DH LA Sbjct: 121 VHLDLQEMSSRQVLKALLEESLQVGVIRPLALPDAVHWVE---LFREPLVAVLRADHPLA 177 Query: 178 G--RQSISAAELAEDAFISIPRMIAPVVYDLIQQHCQLHGFRPRIVLETNLQQTIVNLVG 235 ++ A LAE+ F+ PR +YD + + GF PRI E + TI+ LV Sbjct: 178 AGSEDGLAIAALAEEPFVFFPRSYGTGLYDQVIALTRQAGFSPRIAQEASEAMTIIGLVS 237 Query: 236 EGLGVALVPTSMQAMHLDTTVFKPLIGAPMVEVAV--IWNKDNTNPCIRTFAD 286 GLGV+++P S + +D V++ L P AV + ++ +P +F D Sbjct: 238 AGLGVSILPASFRRTRVDGVVYRTL-SDPEATTAVWLVRRQNEGSPLALSFID 289 >STM3121 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 292 Score = 176 bits (445), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 102/287 (35%), Positives = 159/287 (55%), Gaps = 5/287 (1%) Query: 2 IELRHLTYFRTVAETLHFGRAAELLHISQPPLTRQIAALEKELGAQLFDRSKRAIQLTAA 61 +ELRH+ YF VAE HF RAA L I QPPL++QI LE+ELGAQLF R +LT A Sbjct: 1 MELRHIRYFLAVAEERHFTRAATKLGIGQPPLSQQIKDLERELGAQLFRRVPHGAELTEA 60 Query: 62 GKYFYRDTTEIFKALERAKRNVSSSSTGKSGALKVGFMMSTAYN-ILPSVTRHYSAAYPE 120 GK FY + RA + G+SG L+VGF S A+N ++P R + AYP+ Sbjct: 61 GKAFYDVVKGMPATATRAVLAAQRVARGESGVLRVGFTASAAFNSVVPGAIRTFKRAYPD 120 Query: 121 VDMRLTEYVPNLLATDIEDEKIDVGIMYRP--EDCRRLDSHTIYAEPLLAVLPRDHRLAG 178 V ++L E LA ++ + +DV + RP R + EP++ VL H A Sbjct: 121 VRLQLEEGNTTQLADELNEGSLDVAFL-RPGFTGNERFQLRLLSEEPMVIVLAETHPAAA 179 Query: 179 RQSISAAELAEDAFISIPRMIAPVVYDLIQQHCQLHGFRPRIVLETNLQQTIVNLVGEGL 238 + I+ + L ++ F+ PR I +YD + + C GF P+I +++NLV + Sbjct: 180 CKQIALSILKDEFFLLFPREIGLSLYDAVIKACGKAGFEPKIGQLVPQISSVINLVSAEM 239 Query: 239 GVALVPTSMQAMHLDTTVFKPLIGA-PMVEVAVIWNKDNTNPCIRTF 284 GV++VP SM+ +++ V++P+ P+ ++A+ + + +T+P +R F Sbjct: 240 GVSMVPDSMRQVNVKGVVYRPVADQMPVAKLALAYRRGDTSPTLRNF 286 >CC3045 Non COG Length = 296 Score = 172 bits (435), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 99/287 (34%), Positives = 158/287 (55%), Gaps = 7/287 (2%) Query: 2 IELRHLTYFRTVAETLHFGRAAELLHISQPPLTRQIAALEKELGAQLFDRSKRAIQLTAA 61 +++R +F VAETLHFGRAAE L I+QPPL++ I ALEK LGA LF R+KR ++LTA Sbjct: 1 MDIRQFRHFAAVAETLHFGRAAERLGITQPPLSQSIQALEKALGAPLFARTKRHVELTAL 60 Query: 62 GKYFYRDTTEIFKALERAKRNVSSSSTGKSGALKVGFMMSTAYNILPSVTRHYSAAYPEV 121 G+ + E A++ G++G L + F+ + Y++LP + R Y+ A+P V Sbjct: 61 GRQWLPHVLEALAAVDALPDTARRLRDGQTGYLSLSFVSTADYSVLPDLVRRYAEAFPGV 120 Query: 122 DMRLTEYVPNLLATDIEDEKIDVGIMYRPEDCRRLDSHTIY----AEPLLAVLPRDHRLA 177 +++L E ++ I+ + GI+ P + R L + Y +EPL+AV P Sbjct: 121 EIQLVEATSDVQVPAIQAGERHAGIIIPPPN-RSLPAALAYRRLVSEPLVAVTPEAWGAE 179 Query: 178 GRQSISAAELAEDAFISIPRMIAPVVYDLIQQHCQLHGFRPRIVLETNLQQTIVNLVGEG 237 G ++A LA+ + PR +AP +DL+ + G RIV E QTI++LV G Sbjct: 180 GPLDLAA--LADVPLVLFPRTVAPAFHDLVTGYVAARGQPVRIVQEAIQMQTIISLVSAG 237 Query: 238 LGVALVPTSMQAMHLDTTVFKPLIGAPMVEVAVIWNKDNTNPCIRTF 284 LG+AL P S++ + + L+ P++E ++W +D P ++ Sbjct: 238 LGMALAPASLRKLARVGVRYVDLVDPPILETGLVWRRDEAAPTLQGL 284