BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0147.p (233 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO0941 [R] COG0325 Predicted enzyme with a TIM-barrel fold Ype ... 256 4e-68 VC0461 [R] COG0325 Predicted enzyme with a TIM-barrel fold Vch V... 255 7e-68 STM3100 [R] COG0325 Predicted enzyme with a TIM-barrel fold Sty ... 255 7e-68 PM0112 [R] COG0325 Predicted enzyme with a TIM-barrel fold Pmu P... 251 7e-67 PA0394 [R] COG0325 Predicted enzyme with a TIM-barrel fold Pae P... 251 9e-67 >YPO0941 [R] COG0325 Predicted enzyme with a TIM-barrel fold Ype Yersinia pestis Length = 232 Score = 256 bits (653), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 129/232 (55%), Positives = 168/232 (72%), Gaps = 3/232 (1%) Query: 1 MSSIAQNLQHVQQQIAAAAERAGRPAHAVQLLAVSKTFGPQAVLEAVRAGQRAFGENYLQ 60 MS+I QNLQ V+ +IA AA GR V LLAVSKT A+ +A+ AGQ AFGENY+Q Sbjct: 1 MSTIQQNLQDVRARIATAAHNCGRSPEEVTLLAVSKTKPVAAIEKAIAAGQYAFGENYVQ 60 Query: 61 EALEKIAALPLLAPDAPLQWHFIGPIQSNKTRPIAEHFDWVHSVDRLKIAQRLSEQRPAA 120 E ++KI + + L+WHFIGP+QSNK+R +AE+F W H+VDRLKIAQRLS QRPAA Sbjct: 61 EGVDKIHSF---VDNKTLEWHFIGPLQSNKSRLVAENFAWCHTVDRLKIAQRLSAQRPAA 117 Query: 121 LGALNVCLQVNISGEDSKSGLDPAELPAVAAQVAQLPGLKLRGLMAIPAPSEDVTQQRAA 180 + ALNV +Q+NIS E SK+G+ +ELPA+A ++ LP L LRGLMAIPAP D +Q A Sbjct: 118 MPALNVLIQINISDEQSKAGISLSELPALADSISTLPNLCLRGLMAIPAPEHDYQRQLAV 177 Query: 181 FAAVRSLLAQLQAQGLTLDTLSMGMSADLDAAVAEGASIVRIGSAIFGARHY 232 F + L+A+ +DTLSMGM+ D+DAA++ G+++VRIG+AIFGAR Y Sbjct: 178 FTQMNQAFLTLKARYPQIDTLSMGMTDDMDAAISAGSTLVRIGTAIFGARVY 229 >VC0461 [R] COG0325 Predicted enzyme with a TIM-barrel fold Vch Vibrio cholerae Length = 236 Score = 255 bits (651), Expect = 7e-68, Method: Compositional matrix adjust. Identities = 127/233 (54%), Positives = 164/233 (70%) Query: 1 MSSIAQNLQHVQQQIAAAAERAGRPAHAVQLLAVSKTFGPQAVLEAVRAGQRAFGENYLQ 60 M SI QN++H+ QI +A ++ GR +VQLLAVSKT +A+LEA +AGQR FGENY+Q Sbjct: 1 MRSIQQNIEHITAQIESAQQKCGRARSSVQLLAVSKTKPVEAILEATQAGQRYFGENYVQ 60 Query: 61 EALEKIAALPLLAPDAPLQWHFIGPIQSNKTRPIAEHFDWVHSVDRLKIAQRLSEQRPAA 120 E ++KI P L+WHFIGP+QSNKTR +AEHFDWVH++DR KIA RLSEQRP Sbjct: 61 EGVDKIRYFAEHHPQLALEWHFIGPLQSNKTRLVAEHFDWVHTIDREKIALRLSEQRPVN 120 Query: 121 LGALNVCLQVNISGEDSKSGLDPAELPAVAAQVAQLPGLKLRGLMAIPAPSEDVTQQRAA 180 + L V +QVN SGE SKSG++P +L +A +++LP L LRGLM+IP D Q AA Sbjct: 121 MPPLQVLIQVNTSGEASKSGIEPQQLFTLAELISRLPNLTLRGLMSIPENVPDYPAQLAA 180 Query: 181 FAAVRSLLAQLQAQGLTLDTLSMGMSADLDAAVAEGASIVRIGSAIFGARHYA 233 F + L QL + +DTLSMGMS D+ AA+ G++IVRIG+AIFG R Y+ Sbjct: 181 FTQLAELQQQLAQKYPQIDTLSMGMSGDMQAAIEAGSTIVRIGTAIFGERDYS 233 >STM3100 [R] COG0325 Predicted enzyme with a TIM-barrel fold Sty Salmonella typhimurium LT2 Length = 234 Score = 255 bits (651), Expect = 7e-68, Method: Compositional matrix adjust. Identities = 132/235 (56%), Positives = 169/235 (71%), Gaps = 7/235 (2%) Query: 1 MSSIAQNLQHVQQQIAAAAERAGRPAHAVQLLAVSKTFGPQAVLEAVRAGQRAFGENYLQ 60 M+ IA NL +++ +I+AAA R GR + V LLAVSKT + EA+ AGQRAFGENY+Q Sbjct: 1 MNDIAHNLAYIRDKISAAATRCGRSSEEVTLLAVSKTKPASDIAEAIAAGQRAFGENYVQ 60 Query: 61 EALEKIAALPLLAPDAPLQWHFIGPIQSNKTRPIAEHFDWVHSVDRLKIAQRLSEQRPAA 120 E +EKI + L WHFIGP+QSNK+R +AEHFDW H++DRL+IA RLSEQRP Sbjct: 61 EGVEKIRHFQEAKVEG-LHWHFIGPLQSNKSRLVAEHFDWCHTIDRLRIASRLSEQRPDN 119 Query: 121 LGALNVCLQVNISGEDSKSGLDPAELPAVAAQVAQLPGLKLRGLMAIPAPSEDVTQQRAA 180 L ALNV +Q+NIS E+SKSG+ AEL +AA VA LP L+LRGLMAIPAP D +Q Sbjct: 120 LPALNVLIQINISDENSKSGIPLAELDELAAAVATLPRLRLRGLMAIPAPESDYVRQ--- 176 Query: 181 FAAVRSL---LAQLQAQGLTLDTLSMGMSADLDAAVAEGASIVRIGSAIFGARHY 232 F R + A L+A+ +DTLS+GMS D++AA+A G+++VRIG+AIFGAR Y Sbjct: 177 FEVARQMAVAFAGLKARYPDVDTLSLGMSDDMEAAIAAGSTMVRIGTAIFGARDY 231 >PM0112 [R] COG0325 Predicted enzyme with a TIM-barrel fold Pmu Pasteurella multocida Length = 233 Score = 251 bits (642), Expect = 7e-67, Method: Compositional matrix adjust. Identities = 126/234 (53%), Positives = 167/234 (71%), Gaps = 6/234 (2%) Query: 3 SIAQNLQHVQQQIAAAAERAGRPAHAVQLLAVSKTFGPQAVLEAVRAGQRAFGENYLQEA 62 +I QNL +QQ I A ++A RP AV+LLAVSKT + + +A +AGQ AFGENY+QE Sbjct: 2 TIEQNLAQIQQNIQHAVQQAKRPESAVKLLAVSKTKPVEDIYQAYQAGQTAFGENYVQEG 61 Query: 63 LEKIAALPLLAPDAPLQWHFIGPIQSNKTRPIAEHFDWVHSVDRLKIAQRLSEQRPAALG 122 +EKI + PL+WHFIGP+QSNKT+ +AEHFDW+ ++DR KIA RL+EQRP Sbjct: 62 VEKIQYFA--QKNIPLEWHFIGPLQSNKTKLVAEHFDWMQTLDRKKIADRLNEQRPHYKK 119 Query: 123 ALNVCLQVNISGEDSKSGLDPAELPAVAAQVAQLPGLKLRGLMAIPAPSEDVTQQRAAFA 182 LNV +Q+NIS EDSKSG+ P E+ +A Q+ LP L LRGLMAIPAP++D+ Q AF Sbjct: 120 PLNVLIQINISDEDSKSGIQPNEMLDLAKQIQNLPHLCLRGLMAIPAPTDDLATQEQAFT 179 Query: 183 AVRSLLAQLQAQGL---TLDTLSMGMSADLDAAVAEGASIVRIGSAIFGARHYA 233 + SL QL+ Q L +DTLSMGM+ D+ +A+ G+++VRIG+AIFGAR Y+ Sbjct: 180 QMHSLFEQLK-QALPDAQIDTLSMGMTDDMASAIQCGSTMVRIGTAIFGARDYS 232 >PA0394 [R] COG0325 Predicted enzyme with a TIM-barrel fold Pae Pseudomonas aeruginosa Length = 230 Score = 251 bits (641), Expect = 9e-67, Method: Compositional matrix adjust. Identities = 151/232 (65%), Positives = 167/232 (71%), Gaps = 7/232 (3%) Query: 1 MSSIAQNLQHVQQQIAAAAERAGRPAHAVQLLAVSKTFGPQAVLEAVRAGQRAFGENYLQ 60 MS+IA+N+ V +I AA+ AGR V LLAVSKT AV EA AG R FGENYLQ Sbjct: 1 MSTIAENIAKVAARIREAAQAAGRDPATVGLLAVSKTKPAAAVREAHAAGLRDFGENYLQ 60 Query: 61 EALEKIAALPLLAPDAPLQWHFIGPIQSNKTRPIAEHFDWVHSVDRLKIAQRLSEQRPAA 120 EAL K A L D PL WHFIGPIQSNKTRPIAEHF WVHSVDRLKIAQRLSEQRPA Sbjct: 61 EALGKQAELA----DLPLNWHFIGPIQSNKTRPIAEHFQWVHSVDRLKIAQRLSEQRPAG 116 Query: 121 LGALNVCLQVNISGEDSKSGLDPAELPAVAAQVAQLPGLKLRGLMAIPAPSEDVTQQRAA 180 L LNVCLQVN+SGE SKSG P +LPA+A V QLP L+LRGLMAIP P+ + Q AA Sbjct: 117 LPPLNVCLQVNVSGEASKSGCAPEDLPALAEAVKQLPNLRLRGLMAIPEPTAERAAQHAA 176 Query: 181 FAAVRSLLAQLQAQGLTLDTLSMGMSADLDAAVAEGASIVRIGSAIFGARHY 232 FA L L L LDTLSMGMS DL+AA+ EGA+ VRIG+A+FGAR Y Sbjct: 177 FA---RLRELLLDLNLGLDTLSMGMSDDLEAAIGEGATWVRIGTALFGARDY 225