BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0130.p (356 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr7407 [GEPR] COG0477 Permeases of the major facilitator superf... 207 2e-53 MT3072 [GEPR] COG0477 Permeases of the major facilitator superfa... 80 8e-15 Rv2994 [GEPR] COG0477 Permeases of the major facilitator superfa... 80 8e-15 AGl2008 [GEPR] COG0477 Permeases of the major facilitator superf... 69 1e-11 PA0811 [GEPR] COG0477 Permeases of the major facilitator superfa... 69 2e-11 >mlr7407 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 430 Score = 207 bits (528), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 164/278 (58%), Positives = 184/278 (66%), Gaps = 8/278 (2%) Query: 2 QAAAPVLPRPSPSPSPHRWKVLAAGVAANASFSAVFSGIPVTSVVLRSDYRLSNTQLGLA 61 AAAP SP HRWKVL GVAANASFSA FSGIP T+VVLR Y LSN +LGLA Sbjct: 19 SAAAPAGRVFSPG---HRWKVLGIGVAANASFSATFSGIPATAVVLRQGYHLSNAELGLA 75 Query: 62 LGLLSLGVALGELPWGVLTDRWGDRKVLLAGLLGASAA--LGLLMLYALPGQGAANFAWL 119 LG+L LGVAL ELPWG+LTDRWGDR+VLL G LGA+AA L + ML G + L Sbjct: 76 LGVLGLGVALSELPWGLLTDRWGDRRVLLIG-LGATAAWLLAMAMLVVPTRSGVPDVMLL 134 Query: 120 CAGLMLAGLLGGSVNGASGRAIMGWFGEGERGLAMSIRQTAVPLGGGLGALLLPTLAAQA 179 A L+ GLLGGSVNG+SGRAIMGWF E ERG AMSIRQTAVPLGGGLGAL+LP+LA Sbjct: 135 SASLLFTGLLGGSVNGSSGRAIMGWFRENERGFAMSIRQTAVPLGGGLGALVLPSLALAF 194 Query: 180 GFGAVFAALMAACLASVGLVLRWLREAPVALAHGAAPVVGAASMALRSKLVWRLALGIGL 239 GF AVF L A S RWL E P A A A LR+ VWR+A IGL Sbjct: 195 GFSAVFTLLAGASALSALFAWRWLHEPPAAAH--VAASAAAGPAPLRNIEVWRIATAIGL 252 Query: 240 LCAPQVALLSFGGIFLQESAQASVLAISVLLTLVQLGA 277 LC PQVA+L+F +FL + +AIS L VQ+GA Sbjct: 253 LCFPQVAVLTFASVFLHDFVGLGTVAISASLAAVQIGA 290 >MT3072 [GEPR] COG0477 Permeases of the major facilitator superfamily MtC Mycobacterium tuberculosis CDC1551 Length = 445 Score = 80.1 bits (196), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 76/257 (29%), Positives = 111/257 (43%), Gaps = 9/257 (3%) Query: 19 RWKVLAAGVAANASFSAVFSGIPVTSVVLRSDYRLSNTQLGLALGLLSLGVALGELPWGV 78 RW ++ + AS +G+ L + + GL + S G+ + WG Sbjct: 11 RWAIMIVSLGVTASSFLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMFAWGY 70 Query: 79 LTDRWGDRKVLLAGLLGASAALGLLMLYALPGQGAANFAWLCAGLMLAGLLGGSVNGASG 138 L D G+R V+ G +AA + W+ L L G+ G N A G Sbjct: 71 LLDHVGERMVMAVGSALTAAAAYAAA-------SVHSLLWIGVFLFLGGMAAGGCNSAGG 123 Query: 139 RAIMGWFGEGERGLAMSIRQTAVPLGGGLGALLLPTLAAQAGFGAVFAALMAACLASVGL 198 R + GWF +RGLAM IRQTA PLG GAL++P LA + + + LA+V Sbjct: 124 RLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPELAERGVHAGLMFPAVVCTLAAVAS 183 Query: 199 VLRWLREAPVALAHGAAPVVGAASMALRSKLVWRLALGIGLLCAPQVALLSFGGIFLQES 258 VL + P + A AS S ++WR+ LL PQ ++F ++L Sbjct: 184 VLGIVD--PPRKSRTKASEQELASPYRGSSILWRIHAASALLMMPQTVTVTFMLVWLINH 241 Query: 259 AQASVLAISVLLTLVQL 275 SV VL+T+ QL Sbjct: 242 HGWSVAQAGVLVTISQL 258 >Rv2994 [GEPR] COG0477 Permeases of the major facilitator superfamily Mtu Mycobacterium tuberculosis H37Rv Length = 445 Score = 80.1 bits (196), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 76/257 (29%), Positives = 111/257 (43%), Gaps = 9/257 (3%) Query: 19 RWKVLAAGVAANASFSAVFSGIPVTSVVLRSDYRLSNTQLGLALGLLSLGVALGELPWGV 78 RW ++ + AS +G+ L + + GL + S G+ + WG Sbjct: 11 RWAIMIVSLGVTASSFLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMFAWGY 70 Query: 79 LTDRWGDRKVLLAGLLGASAALGLLMLYALPGQGAANFAWLCAGLMLAGLLGGSVNGASG 138 L D G+R V+ G +AA + W+ L L G+ G N A G Sbjct: 71 LLDHVGERMVMAVGSALTAAAAYAAA-------SVHSLLWIGVFLFLGGMAAGGCNSAGG 123 Query: 139 RAIMGWFGEGERGLAMSIRQTAVPLGGGLGALLLPTLAAQAGFGAVFAALMAACLASVGL 198 R + GWF +RGLAM IRQTA PLG GAL++P LA + + + LA+V Sbjct: 124 RLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPELAERGVHAGLMFPAVVCTLAAVAS 183 Query: 199 VLRWLREAPVALAHGAAPVVGAASMALRSKLVWRLALGIGLLCAPQVALLSFGGIFLQES 258 VL + P + A AS S ++WR+ LL PQ ++F ++L Sbjct: 184 VLGIVD--PPRKSRTKASEQELASPYRGSSILWRIHAASALLMMPQTVTVTFMLVWLINH 241 Query: 259 AQASVLAISVLLTLVQL 275 SV VL+T+ QL Sbjct: 242 HGWSVAQAGVLVTISQL 258 >AGl2008 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 418 Score = 69.3 bits (168), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 70/205 (34%), Positives = 100/205 (48%), Gaps = 20/205 (9%) Query: 9 PRPSPSPSPHRWKVLAAGVAANASFSAVFSGIPVTSVVLRSDYRLSNTQLGLALGLLSLG 68 P P+P+ PH W VLA V + S V GI + R + +S LA+ +++ G Sbjct: 10 PGPAPAADPHIWAVLAVAVGTQTAGSFVSQGIYILVPFWREAFGVSLASASLAVTVMN-G 68 Query: 69 VALGEL-PWGVLTDRWGDRKVLLAGLLGASAALGLLMLYALPGQGAANFA-WLCAGLMLA 126 V + + G D G+R+++ +LG + A+ AA FA L A L+ Sbjct: 69 VQIATMFTLGRAIDIHGERRIVGIAMLGMAIAMAC----------AATFANSLPALLVCI 118 Query: 127 GLLGGS---VNGASGRAIMGWFGEGERGLAMSIRQTAVPLGGGLGALLLPTLAAQAGFGA 183 LGG+ V RAIM WF +RG+A RQ AVP G + A LLP +A + G+ A Sbjct: 119 AFLGGTYAAVQPGGTRAIMRWFPPAKRGIATGFRQAAVPFGTMIAAALLPFMAVRYGWHA 178 Query: 184 VFAALMAACLASVGLVLRW--LREA 206 AA + A ++ VG L W REA Sbjct: 179 --AAWLCAGVSIVGAALFWGLYREA 201 >PA0811 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 415 Score = 68.6 bits (166), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 74/266 (27%), Positives = 122/266 (45%), Gaps = 18/266 (6%) Query: 18 HRWKVLAAGVAANASFSAVFSGIPVTSVVLRSDYRLSNTQLGLALGLLSLGVALGELPWG 77 +RW +L A A GI +V +++D +LS+ Q+GL + L +G L G Sbjct: 13 YRWVILLIATFAQACACFFVQGIGAIAVFVQNDLQLSSLQIGLLVSAAQLVPIVGLLVAG 72 Query: 78 VLTDRWGDRKVLLAGLLGASAALGLLMLYALPGQGAANFAWLCAGLMLAGLLGGSVNGAS 137 L DR+ +R V+ G L + AL A ++ + L++ G + Sbjct: 73 ELLDRYSERLVVGLGTLIVALAL-------CASLWATDYLTILLFLVVVGAGYSTAQPGG 125 Query: 138 GRAIMGWFGEGERGLAMSIRQTAVPLGGGLGALLLPTLAAQAGFGAVF-AALMAACLASV 196 +++ WF + + G AM IRQ +PLGG L A LLP LA G+ + F A + A L ++ Sbjct: 126 SKSVSRWFAKTQLGFAMGIRQAGLPLGGALSAALLPYLAGVYGWRSAFLAGGLVAFLGAL 185 Query: 197 GLVLRWLREAPVALAHGAAPVVGAASMALRSKLVW--------RLALGIGLLCAPQVALL 248 +L + R P A A GA P ++S+L + G+ L+ Q +L Sbjct: 186 AFMLFY-RTPPDAPAPGANPAERDLGAVVKSRLAMITDPAMKNIVCSGVALISV-QYGIL 243 Query: 249 SFGGIFLQESAQASVLAISVLLTLVQ 274 F ++L E+ + + + LL + Q Sbjct: 244 VFTVLYLHETLEIGIGMAATLLFVAQ 269