BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0129.p (201 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2196 [K] COG1309 Transcriptional regulator Pae Pseudomonas aer... 191 1e-48 RSc1201 [K] COG1309 Transcriptional regulator Rso Ralstonia sola... 150 2e-36 YPO2378 [K] COG1309 Transcriptional regulator Ype Yersinia pestis 141 1e-33 STM1437 [K] COG1309 Transcriptional regulator Sty Salmonella typ... 139 3e-33 Z2666 [K] COG1309 Transcriptional regulator EcZ Escherichia coli... 135 5e-32 >PA2196 [K] COG1309 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 194 Score = 191 bits (485), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 98/195 (50%), Positives = 129/195 (66%), Gaps = 3/195 (1%) Query: 1 MREHYGENKRNILMAGRALIAQKGYSSVGLSEILAAAAIPKGSFYHYFGSKEQYGRELIE 60 M+ Y + ++++L G ++A KG+S VGL+EIL +A +PKGSFYHYF SKEQ+G+ L+E Sbjct: 1 MKTSYDDTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLE 60 Query: 61 HYVAGYLESLERVLGDPAHGASARERLLTYWGYWLESQCCQELEQRCLVVKLSAEVADLS 120 Y YL +++ P G +ARERL++YW WL++ C EQRCLVVKLSAEVADLS Sbjct: 61 DYFRVYLADMDQRFSAP--GLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLS 118 Query: 121 EDMRQALHQGTQAFIERIAACIAQGIAEGSLHTVLHPLATATMLYQQWLGASLLSRLSRD 180 E MR L G+ IER+ C+ QG +GSL A+ LYQ WLGASLLS+L R Sbjct: 119 ESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPC-DARHMASALYQLWLGASLLSKLHRS 177 Query: 181 RAPMEAAMLVTRRVL 195 P+E AM TR +L Sbjct: 178 PGPLETAMQTTRSLL 192 >RSc1201 [K] COG1309 Transcriptional regulator Rso Ralstonia solanacearum Length = 209 Score = 150 bits (379), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 81/193 (41%), Positives = 110/193 (56%), Gaps = 2/193 (1%) Query: 7 ENKRNILMAGRALIAQKGYSSVGLSEILAAAAIPKGSFYHYFGSKEQYGRELIEHYVAGY 66 + + IL AG LI +G+S+VGL+EIL A +PKGSFY+YF SKE +G L+E Y Y Sbjct: 18 DTRDRILDAGAELILGRGFSAVGLAEILGRAQVPKGSFYYYFDSKENFGVALLERYFQDY 77 Query: 67 LESLERVLGDPAHGASARERLLTYWGYWLESQCCQELEQRCLVVKLSAEVADLSEDMRQA 126 + + D +ARERL+ Y+ W++ E CL VKLS EV+DLSE MR+ Sbjct: 78 EAGVVSLFNDTR--MTARERLIRYFAAWIDLHERSACEVTCLAVKLSGEVSDLSEPMRKV 135 Query: 127 LHQGTQAFIERIAACIAQGIAEGSLHTVLHPLATATMLYQQWLGASLLSRLSRDRAPMEA 186 L G +ERIAA + G+A+GSL V P A LY W+G +LL++ R AP Sbjct: 136 LSAGMTRMVERIAAAVEAGVADGSLAPVADPRGLAEGLYAMWMGGALLAKAHRSTAPFHG 195 Query: 187 AMLVTRRVLVLPE 199 + T +L P Sbjct: 196 CVAQTEGLLAKPN 208 >YPO2378 [K] COG1309 Transcriptional regulator Ype Yersinia pestis Length = 199 Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 79/182 (43%), Positives = 104/182 (57%), Gaps = 2/182 (1%) Query: 7 ENKRNILMAGRALIAQKGYSSVGLSEILAAAAIPKGSFYHYFGSKEQYGRELIEHYVAGY 66 + + ++L G L + G++ +GLS +L A IPKGSFYHYF SKE +G +++ Y Y Sbjct: 10 DTREHLLATGERLSLRLGFNGMGLSLLLTTAGIPKGSFYHYFRSKEVFGEAMLQRYFDRY 69 Query: 67 LESLERVLGDPAHGASARERLLTYWGYWLESQCCQELEQRCLVVKLSAEVADLSEDMRQA 126 +E +L R LL Y+ + + C E CL VKLSAEV+DLSE MR A Sbjct: 70 DAEMESLLAGSQ--GDKRHHLLHYFAQSIANYCGSECHNACLAVKLSAEVSDLSEPMRHA 127 Query: 127 LHQGTQAFIERIAACIAQGIAEGSLHTVLHPLATATMLYQQWLGASLLSRLSRDRAPMEA 186 L GT I R+ I GI EGSL TVL P ATA LY WLGASL +++ AP+ Sbjct: 128 LDIGTARVIGRLQDAIEAGIDEGSLRTVLSPAATAETLYALWLGASLRAKVKHSVAPLTC 187 Query: 187 AM 188 A+ Sbjct: 188 AL 189 >STM1437 [K] COG1309 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 199 Score = 139 bits (351), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 78/197 (39%), Positives = 112/197 (56%), Gaps = 10/197 (5%) Query: 7 ENKRNILMAGRALIAQKGYSSVGLSEILAAAAIPKGSFYHYFGSKEQYGRELIEHYVAGY 66 + + ++L G L Q+G++ +GLSE+L A +PKGSFYHYF SKE +G ++E + A Y Sbjct: 8 DTREHLLATGEQLCMQRGFTGMGLSELLKTAQVPKGSFYHYFRSKEAFGVAMLERHYACY 67 Query: 67 LESLERVLGDPAHGASA----RERLLTYWGYWLESQCCQELEQRCLVVKLSAEVADLSED 122 + L AH S R+RLL ++ L+ C Q CL VKLSAEV DLSED Sbjct: 68 HQRL------TAHFTSGPGNHRDRLLAWYQETLKQFCQQGAISGCLTVKLSAEVCDLSED 121 Query: 123 MRQALHQGTQAFIERIAACIAQGIAEGSLHTVLHPLATATMLYQQWLGASLLSRLSRDRA 182 MR + +G Q + +A + G LH PL A +LY WLGA+L +++SR A Sbjct: 122 MRSTMDKGAQEIMALLARALEDGRNSHCLHFTGQPLPQAQVLYALWLGANLQAKISRSAA 181 Query: 183 PMEAAMLVTRRVLVLPE 199 P+E A+ + ++ PE Sbjct: 182 PLENALAHVKTIIATPE 198 >Z2666 [K] COG1309 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 199 Score = 135 bits (341), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 76/199 (38%), Positives = 112/199 (56%), Gaps = 3/199 (1%) Query: 1 MREHYGENKRNILMA-GRALIAQKGYSSVGLSEILAAAAIPKGSFYHYFGSKEQYGRELI 59 M +H + R L+A G L Q+G++ +GLSE+L A +PKGSFYHYF SKE +G ++ Sbjct: 1 MNKHTEHDTREHLLATGEQLCLQRGFTGMGLSELLKTAEVPKGSFYHYFRSKEAFGVAML 60 Query: 60 EHYVAGYLESLERVLGDPAHGASARERLLTYWGYWLESQCCQELEQRCLVVKLSAEVADL 119 E + A Y + L +L + R+R+L Y+ L C CL VKLSAEV DL Sbjct: 61 ERHYATYHQRLTELLQSGE--GNYRDRILAYYQQTLNQFCQHGTISGCLTVKLSAEVCDL 118 Query: 120 SEDMRQALHQGTQAFIERIAACIAQGIAEGSLHTVLHPLATATMLYQQWLGASLLSRLSR 179 SEDMR A+ +G + I ++ + G L PL A +LY WLGA+L +++SR Sbjct: 119 SEDMRSAMDKGARGVIALLSQALENGRDSHCLTFCGEPLQQAQVLYALWLGANLQAKISR 178 Query: 180 DRAPMEAAMLVTRRVLVLP 198 + P+E A+ + ++ P Sbjct: 179 NSEPLENALAHVKTIIATP 197