BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0128.p (343 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2197 [R] COG2130 Putative NADP-dependent oxidoreductases Pae P... 446 e-125 STM1589 [R] COG2130 Putative NADP-dependent oxidoreductases Sty ... 427 e-119 yncB [R] COG2130 Putative NADP-dependent oxidoreductases Eco Esc... 419 e-117 ZyncB [R] COG2130 Putative NADP-dependent oxidoreductases EcZ Es... 419 e-117 ECs2053 [R] COG2130 Putative NADP-dependent oxidoreductases Ecs ... 419 e-117 >PA2197 [R] COG2130 Putative NADP-dependent oxidoreductases Pae Pseudomonas aeruginosa Length = 345 Score = 446 bits (1148), Expect = e-125, Method: Compositional matrix adjust. Identities = 220/345 (63%), Positives = 269/345 (77%), Gaps = 7/345 (2%) Query: 1 MTKTTAQTNRRIVLASRPTGAPTADNFRLEEVAIPALEEGQLLLRGQWLSLDPYMRGRMS 60 M+++T Q NRRIVLASRP GAPT DNFR+E+V +P GQ+LLR +LSLDPYMRGRMS Sbjct: 1 MSQST-QVNRRIVLASRPHGAPTRDNFRIEQVPLPEPGAGQVLLRTVYLSLDPYMRGRMS 59 Query: 61 DAPSYAPPVEIGGVMTGGVVSRVEASRHPEFKEGDLVMAYTGWQEYAVSDGTGVNKLPAG 120 DAPSYAPPVE+G VM GG VSRVEAS HP FK GD V++ GWQ+YA+SDG+G+ +L Sbjct: 60 DAPSYAPPVELGAVMVGGTVSRVEASNHPGFKVGDWVLSANGWQDYALSDGSGLARLGES 119 Query: 121 FAHPSHALGVLGMPGYTAYAGLIDIGQPRPGETVVVAAATGAVGSLVGQIAKLRGCHVVG 180 HPS+ALG+LGMPG+TAY GL+DIG+P+ GET+VVAAATG VG+ VGQI KL+GC VVG Sbjct: 120 PEHPSYALGLLGMPGFTAYMGLLDIGKPQAGETLVVAAATGPVGATVGQIGKLKGCRVVG 179 Query: 181 IAGGAQKCEAAVKELGFDACIDHRAADFPEQLKAACPRGIDVYFENVGGAVLDAVFPLLN 240 +AGGA+KC AV+ LGFDAC+DH AADF E+L ACP GID+Y+ENVGG V DAVFPLLN Sbjct: 180 VAGGAEKCRHAVQVLGFDACLDHHAADFAERLAEACPDGIDIYYENVGGKVFDAVFPLLN 239 Query: 241 IHARVPVCGLIAHYNGGTLATDS---AAILRRTLTQRMRVQGFIIFDYYVNRPDLHAAFQ 297 AR+PVCG++AHYN L A++ L +R++VQGFIIFD Y +R D FQ Sbjct: 240 AKARIPVCGIVAHYNDTELPPGPDRLPALMGTILRKRIKVQGFIIFDDYGHRYD---EFQ 296 Query: 298 QEVGNWLKQGKLHYREDVVQGLENAPEAFMGLLQGKNFGKLVVKL 342 +++ W G + YRE+ V GLENAPEAF GLLQG+NFGKLVV++ Sbjct: 297 RDMSKWFADGLIQYREERVDGLENAPEAFFGLLQGRNFGKLVVRV 341 >STM1589 [R] COG2130 Putative NADP-dependent oxidoreductases Sty Salmonella typhimurium LT2 Length = 356 Score = 427 bits (1097), Expect = e-119, Method: Compositional matrix adjust. Identities = 212/343 (61%), Positives = 257/343 (74%), Gaps = 6/343 (1%) Query: 3 KTTAQTNRRIVLASRPTGAPTADNFRLEEVAIPALEEGQLLLRGQWLSLDPYMRGRMSDA 62 K NRR VLASRP GAP DNFRLEE + EGQ+LLR +LSLDPYMRGRMSD Sbjct: 13 KQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLSLDPYMRGRMSDE 72 Query: 63 PSYAPPVEIGGVMTGGVVSRVEASRHPEFKEGDLVMAYTGWQEYAVSDGTGVNKLPAGFA 122 PSYAPPVE G VM GG VSRV AS HP+++ + V++Y GWQ+Y +SDG G+ KL Sbjct: 73 PSYAPPVEPGCVMVGGTVSRVVASNHPDYRPDEWVLSYNGWQDYDISDGEGLVKLGDNPQ 132 Query: 123 HPSHALGVLGMPGYTAYAGLIDIGQPRPGETVVVAAATGAVGSLVGQIAKLRGCHVVGIA 182 HPS +LG+LGMPG+TAY GL+DIGQP+ GET+VVAAATG VG+ VGQI KL+GC VVGIA Sbjct: 133 HPSWSLGILGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGIA 192 Query: 183 GGAQKCEAAVKELGFDACIDHRAADFPEQLKAACPRGIDVYFENVGGAVLDAVFPLLNIH 242 GGA+KC A LGFD C+DH A +FP+QL ACP+GID+Y+ENVGG V DAV PLLN Sbjct: 193 GGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGKVFDAVLPLLNTS 252 Query: 243 ARVPVCGLIAHYNGGTL--ATDSAAILRRT-LTQRMRVQGFIIFDYYVNRPDLHAAFQQE 299 AR+P+CGL++ YN L D +L T L +R+R+QGFII Y +R +H FQQE Sbjct: 253 ARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYGHR--IH-EFQQE 309 Query: 300 VGNWLKQGKLHYREDVVQGLENAPEAFMGLLQGKNFGKLVVKL 342 +G W+K+GK+HYRE + GLENAPEAFMGLL GKNFGK+V++L Sbjct: 310 MGRWIKEGKIHYREQITDGLENAPEAFMGLLAGKNFGKVVIRL 352 >yncB [R] COG2130 Putative NADP-dependent oxidoreductases Eco Escherichia coli K12 Length = 376 Score = 419 bits (1076), Expect = e-117, Method: Compositional matrix adjust. Identities = 205/339 (60%), Positives = 257/339 (75%), Gaps = 6/339 (1%) Query: 7 QTNRRIVLASRPTGAPTADNFRLEEVAIPALEEGQLLLRGQWLSLDPYMRGRMSDAPSYA 66 Q NRR VLASRP GAP +NFRLEE + EGQ+LLR +LSLDPYMRGRMSD PSY+ Sbjct: 37 QRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSDEPSYS 96 Query: 67 PPVEIGGVMTGGVVSRVEASRHPEFKEGDLVMAYTGWQEYAVSDGTGVNKLPAGFAHPSH 126 PPV+IGGVM GG VSRV S HP+++ GD V+ Y+GWQ+Y +S G + KL +PS Sbjct: 97 PPVDIGGVMVGGTVSRVVESNHPDYQSGDWVLGYSGWQDYDISSGDDLVKLGDHPQNPSW 156 Query: 127 ALGVLGMPGYTAYAGLIDIGQPRPGETVVVAAATGAVGSLVGQIAKLRGCHVVGIAGGAQ 186 +LGVLGMPG+TAY GL+DIGQP+ GET+VVAAATG VG+ VGQI KL+GC VVG+AGGA+ Sbjct: 157 SLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGVAGGAE 216 Query: 187 KCEAAVKELGFDACIDHRAADFPEQLKAACPRGIDVYFENVGGAVLDAVFPLLNIHARVP 246 KC A + LGFD C+DH A DF EQL ACP+GID+Y+ENVGG V DAV PLLN AR+P Sbjct: 217 KCRHATEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNTSARIP 276 Query: 247 VCGLIAHYNGGTL--ATDSAAILRRT-LTQRMRVQGFIIFDYYVNRPDLHAAFQQEVGNW 303 VCGL++ YN L D +L T L +R+R+QGFII Y +R +H FQ+E+G W Sbjct: 277 VCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIAQDYGHR--IH-EFQREMGQW 333 Query: 304 LKQGKLHYREDVVQGLENAPEAFMGLLQGKNFGKLVVKL 342 +K+ K+HYRE++ GLENAP+ F+GLL+GKNFGK+V+++ Sbjct: 334 VKEDKIHYREEITDGLENAPQTFIGLLKGKNFGKVVIRV 372 >ZyncB [R] COG2130 Putative NADP-dependent oxidoreductases EcZ Escherichia coli O157:H7 EDL933 Length = 376 Score = 419 bits (1076), Expect = e-117, Method: Compositional matrix adjust. Identities = 205/339 (60%), Positives = 257/339 (75%), Gaps = 6/339 (1%) Query: 7 QTNRRIVLASRPTGAPTADNFRLEEVAIPALEEGQLLLRGQWLSLDPYMRGRMSDAPSYA 66 Q NRR VLASRP GAP +NFRLEE + EGQ+LLR +LSLDPYMRGRMSD PSY+ Sbjct: 37 QRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSDEPSYS 96 Query: 67 PPVEIGGVMTGGVVSRVEASRHPEFKEGDLVMAYTGWQEYAVSDGTGVNKLPAGFAHPSH 126 PPV+IGGVM GG VSRV S HP+++ GD V+ Y+GWQ+Y +S G + KL +PS Sbjct: 97 PPVDIGGVMVGGTVSRVVESNHPDYQSGDWVLGYSGWQDYDISSGDDLVKLGDHPQNPSW 156 Query: 127 ALGVLGMPGYTAYAGLIDIGQPRPGETVVVAAATGAVGSLVGQIAKLRGCHVVGIAGGAQ 186 +LGVLGMPG+TAY GL+DIGQP+ GET+VVAAATG VG+ VGQI KL+GC VVG+AGGA+ Sbjct: 157 SLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGVAGGAE 216 Query: 187 KCEAAVKELGFDACIDHRAADFPEQLKAACPRGIDVYFENVGGAVLDAVFPLLNIHARVP 246 KC A + LGFD C+DH A DF EQL ACP+GID+Y+ENVGG V DAV PLLN AR+P Sbjct: 217 KCRHATEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNTSARIP 276 Query: 247 VCGLIAHYNGGTL--ATDSAAILRRT-LTQRMRVQGFIIFDYYVNRPDLHAAFQQEVGNW 303 VCGL++ YN L D +L T L +R+R+QGFII Y +R +H FQ+E+G W Sbjct: 277 VCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIAQDYGHR--IH-EFQREMGQW 333 Query: 304 LKQGKLHYREDVVQGLENAPEAFMGLLQGKNFGKLVVKL 342 +K+ K+HYRE++ GLENAP+ F+GLL+GKNFGK+V+++ Sbjct: 334 VKEDKIHYREEITDGLENAPQTFIGLLKGKNFGKVVIRV 372 >ECs2053 [R] COG2130 Putative NADP-dependent oxidoreductases Ecs Escherichia coli O157:H7 Length = 376 Score = 419 bits (1076), Expect = e-117, Method: Compositional matrix adjust. Identities = 205/339 (60%), Positives = 257/339 (75%), Gaps = 6/339 (1%) Query: 7 QTNRRIVLASRPTGAPTADNFRLEEVAIPALEEGQLLLRGQWLSLDPYMRGRMSDAPSYA 66 Q NRR VLASRP GAP +NFRLEE + EGQ+LLR +LSLDPYMRGRMSD PSY+ Sbjct: 37 QRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSDEPSYS 96 Query: 67 PPVEIGGVMTGGVVSRVEASRHPEFKEGDLVMAYTGWQEYAVSDGTGVNKLPAGFAHPSH 126 PPV+IGGVM GG VSRV S HP+++ GD V+ Y+GWQ+Y +S G + KL +PS Sbjct: 97 PPVDIGGVMVGGTVSRVVESNHPDYQSGDWVLGYSGWQDYDISSGDDLVKLGDHPQNPSW 156 Query: 127 ALGVLGMPGYTAYAGLIDIGQPRPGETVVVAAATGAVGSLVGQIAKLRGCHVVGIAGGAQ 186 +LGVLGMPG+TAY GL+DIGQP+ GET+VVAAATG VG+ VGQI KL+GC VVG+AGGA+ Sbjct: 157 SLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGVAGGAE 216 Query: 187 KCEAAVKELGFDACIDHRAADFPEQLKAACPRGIDVYFENVGGAVLDAVFPLLNIHARVP 246 KC A + LGFD C+DH A DF EQL ACP+GID+Y+ENVGG V DAV PLLN AR+P Sbjct: 217 KCRHATEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNTSARIP 276 Query: 247 VCGLIAHYNGGTL--ATDSAAILRRT-LTQRMRVQGFIIFDYYVNRPDLHAAFQQEVGNW 303 VCGL++ YN L D +L T L +R+R+QGFII Y +R +H FQ+E+G W Sbjct: 277 VCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIAQDYGHR--IH-EFQREMGQW 333 Query: 304 LKQGKLHYREDVVQGLENAPEAFMGLLQGKNFGKLVVKL 342 +K+ K+HYRE++ GLENAP+ F+GLL+GKNFGK+V+++ Sbjct: 334 VKEDKIHYREEITDGLENAPQTFIGLLKGKNFGKVVIRV 372