BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0106.p (281 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0871 [E] COG0169 Shikimate 5-dehydrogenase Bme Brucella mel... 139 9e-33 BMEII0059 [E] COG0169 Shikimate 5-dehydrogenase Bme Brucella mel... 130 4e-30 lin2338 [E] COG0169 Shikimate 5-dehydrogenase Lin Listeria innocua 104 3e-22 MK0117 [E] COG0169 Shikimate 5-dehydrogenase Mka Methanopyrus ka... 100 3e-21 alr2057 [E] COG0169 Shikimate 5-dehydrogenase Nos Nostoc sp. PCC... 100 5e-21 >BMEII0871 [E] COG0169 Shikimate 5-dehydrogenase Bme Brucella melitensis Length = 283 Score = 139 bits (349), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 86/263 (32%), Positives = 137/263 (52%), Gaps = 4/263 (1%) Query: 4 ITGTTRIFPVIGWPVEQVKAPTLFNAYFEHHGIDARVIPFKIEPERYCEAVRMFMKTENV 63 ITG T+++ ++ P+ VK P N +F G D ++PF + PE + V K EN+ Sbjct: 13 ITGHTKLYGIVANPIAHVKTPEEVNKHFAALGHDGVLVPFHVLPENLAQFVNSLRKLENL 72 Query: 64 GGIFVSIPHKPMTLEAVEQSTLRARVAGACNAVYRDADGVIWGDLIDGEGFIRALARTAA 123 GG+ V++PHK L ++ A GA N + R++DG + G ++DG+GF+ L + Sbjct: 73 GGLVVTVPHKTAILSLCDRLEGDAAAIGAANVIRRESDGTLVGVMLDGKGFVSGLVASDI 132 Query: 124 DRPLVWNKTRALVVGTGGVGCAIVASLAAQGVAEISVFDTNRAGAEALLARTAAAFPATR 183 D A ++G GG AI +LA GVA +++ + + A L AR + +PA + Sbjct: 133 D----VTGMNACLLGAGGAASAIAFALAEAGVARLTIVNRSEDKARDLAARVSERYPAVQ 188 Query: 184 VGFAQPDASGFDLLVNCTPLGMHVGDPMPFALEGVRRDAIVADCGMKIEMSQLLVQAQAL 243 + P + DL++N T LG+ GDP+P IVA+ M+ E++ LL A+ Sbjct: 189 IDAGAPQTASRDLIINATSLGLRAGDPLPLDDLAFHAGQIVAEVIMEPEVTPLLAAARDK 248 Query: 244 GCRIQKGKEMLIEQAPLYLDLFG 266 G RI G+ ML +Q L + G Sbjct: 249 GARIHFGRPMLRQQIRLMAEHMG 271 >BMEII0059 [E] COG0169 Shikimate 5-dehydrogenase Bme Brucella melitensis Length = 261 Score = 130 bits (327), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 90/263 (34%), Positives = 132/263 (50%), Gaps = 7/263 (2%) Query: 4 ITGTTRIFPVIGWPVEQVKAPTLFNAYFEHHGIDARVIPFKIEPERYCEAVRMFMKTENV 63 +TG TR+F +I PV V+ P NA F G D V+P + A N Sbjct: 3 VTGHTRVFAIIADPVHHVRTPQALNALFAARGYDGIVVPAAVPASGLKYAAAALRAFGNW 62 Query: 64 GGIFVSIPHKPMTLEAVEQSTLRARVAGACNAVYRDADGVIWGDLIDGEGFIRALARTAA 123 GG V++PHK ++ T RA+ AGA N + R+ADG + G+L+DG GF+R LA Sbjct: 63 GGFIVTVPHKTEMPAFCDRLTPRAQAAGAVNVIRREADGSLTGELLDGVGFVRGLANAGH 122 Query: 124 DRPLVWNKTRALVVGTGGVGCAIVASLAAQ-GVAEISVFDTNRAGAEALLARTAAAFPAT 182 D K R++ + G + +A A+ GV ++V + + A L+AR FPA Sbjct: 123 DV-----KGRSVYLAGAGGAASAIAFALAEAGVVRLTVVNRSSEKAGQLVARLKEHFPAG 177 Query: 183 RVGFAQPDASGFDLLVNCTPLGMHVGDPMPFALEGVRRDAIVADCGMKIEMSQLLVQAQA 242 +Q +G D++VN T LG+ GD +P + +R + +VA+ M E++ LL A+ Sbjct: 178 MF-VSQGTPAGHDIIVNGTSLGLKEGDALPVDPQYLRPEMLVAEVIMSPEVTPLLQIAKD 236 Query: 243 LGCRIQKGKEMLIEQAPLYLDLF 265 GC I GK ML Q D F Sbjct: 237 SGCSIHPGKAMLDGQLAEMFDFF 259 >lin2338 [E] COG0169 Shikimate 5-dehydrogenase Lin Listeria innocua Length = 289 Score = 104 bits (259), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 86/282 (30%), Positives = 134/282 (47%), Gaps = 29/282 (10%) Query: 2 KAITGTTRIFPVIGWPVEQVKAPTLFNAYFEHHGIDARVIPFKIEPERYCEAVRMFMKTE 61 K I+G+TR+ +IG PV+ K+P ++N F+ G+D + F I + +A+ +KT Sbjct: 3 KRISGSTRLLSLIGTPVDHSKSPIMYNYSFQKAGLDYAYLAFDIPVSKVADAIAA-IKTF 61 Query: 62 NVGGIFVSIPHKPMTLEAVEQSTLRARVAGACNAVYRDADGVIWGDLIDGEGFIRALART 121 N+ G V++P K L+ +++ + AR+ GA N + + DG + G + DG GF L + Sbjct: 62 NLRGSNVTMPCKSEVLKYMDELSPAARMIGAVNTIINE-DGKLTGHITDGLGFASNLRDS 120 Query: 122 AADRPLVWNKTRALVVGTGGVGCAIVASLAAQGVAEISVF---DTNRAGAEALLARTAAA 178 D V K + ++G GG AI A G EI++F D A+ +A Sbjct: 121 GVD---VAGK-KMTIIGAGGAATAIQVQCALDGAKEIAIFNIKDDFYEKAKQTIASIKQE 176 Query: 179 FPATRVG-FAQPDASGF-------DLLVNCTPLGMH-------VGDPMPFALEGVRRDAI 223 P V + DA+ D+LVN T +GMH V D F R+D I Sbjct: 177 VPDCIVHIYDLNDAAKLHEEIATSDILVNATLVGMHPHENETPVKDTTVF-----RKDLI 231 Query: 224 VADCGMKIEMSQLLVQAQALGCRIQKGKEMLIEQAPLYLDLF 265 V D + ++LL+ A+A G + G ML+ Q LF Sbjct: 232 VTDVVYNPKKTRLLLDAEAAGSKTIGGLGMLLWQGAEAYKLF 273 >MK0117 [E] COG0169 Shikimate 5-dehydrogenase Mka Methanopyrus kandleri AV19 Length = 290 Score = 100 bits (250), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 84/278 (30%), Positives = 130/278 (46%), Gaps = 15/278 (5%) Query: 3 AITGTTRIFPVIGWPVEQVKAPTLFNAYFEHHGIDARVIPFKIEPERYCEAVRMFMKTEN 62 ++ T + +IG PVE +P + NA F+ G++ + F + PER AVR Sbjct: 6 SVDAETNVVGLIGHPVEHSLSPAMHNAAFKELGLNYVYLAFDVPPERLEGAVRGAADL-G 64 Query: 63 VGGIFVSIPHKPMTLEAVEQSTLRARVAGACNAVYRDADGVIWGDLIDGEGFIRALARTA 122 + G+ V+IPHK +E ++ A + GA N V R + G I G DGEGF+RAL Sbjct: 65 IVGLNVTIPHKEAVMELCDELDRDAELIGAVNTV-RFSRGKIEGFNTDGEGFLRALREET 123 Query: 123 ADRPLVWNKTRALVVGTGGVGCAIVASLAAQGVAEISVFD--TNRAGAEALLARTAAAFP 180 P T+++++G GG A+ LA +G EI + + +RA A + Sbjct: 124 YFDP---RGTKSVILGAGGAARAVSFKLATEGADEIVIANRTVDRAERLAEELKEKVGVK 180 Query: 181 ATRVGFA----QPDASGFDLLVNCTPLGMHVGDPMP--FALEGVRRDAIVADCGMKIEMS 234 A +G + + DLLV+ TP+GM+ + P + + D IV D + Sbjct: 181 ARAIGLDGDEIERELRDADLLVDATPVGMYPNEDEPPLVTADQMHEDLIVNDLVYNPPRT 240 Query: 235 QLLVQAQALGCRIQKGKEMLIEQAPLYLDLFGWPGVAA 272 +LL +A+ G G ML+ Q L +L W G A Sbjct: 241 RLLEEAEKAGATPVSGVGMLVYQGALAFEL--WTGEEA 276 >alr2057 [E] COG0169 Shikimate 5-dehydrogenase Nos Nostoc sp. PCC 7120 Length = 289 Score = 100 bits (248), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 85/266 (31%), Positives = 120/266 (45%), Gaps = 20/266 (7%) Query: 4 ITGTTRIFPVIGWPVEQVKAPTLFNAYFEHHGIDARVIPFKIEPERYCEAVRMFMKTENV 63 ITG T++ VIG PVE +P + NA G+D +PF I P+ EA + T V Sbjct: 2 ITGKTKLLGVIGHPVEHSLSPVMHNAAIAQLGLDYVYLPFPIAPDN-LEAAIALLATIGV 60 Query: 64 GGIFVSIPHKPMTLEAVEQSTLRARVAGACNAVYRDADGVIWGDLIDGEGFIRALARTAA 123 G V+IPHK + + + + A+ GA N V R + + G D EGFI L T Sbjct: 61 VGFSVTIPHKQAIIPLLSEISPVAQAIGAVNTVTRQNNQWV-GTNTDIEGFIAPLQTTYK 119 Query: 124 DRPLVWNKTRALVVGTGGVGCAIVASLAAQGVAEISVFDTNRAGAEAL--------LART 175 W++ A+++G GG A+VA G AEI V N E +A Sbjct: 120 RD---WSQQIAVILGNGGAARAVVAGCYQLGFAEIHVVGRNVQRLEEFRHSWENSPIAEN 176 Query: 176 AAAFPATRVGFAQPDASGFDLLVNCTPLGMHVG-DPMPFALE---GVRRDAIVADCGMKI 231 + P A +LLVN TP+GM+ D P + E ++ I D Sbjct: 177 LQVHTWDYLAKLIPQA---NLLVNTTPIGMYPQVDESPLSAEELVNLQTGTIAYDLIYIP 233 Query: 232 EMSQLLVQAQALGCRIQKGKEMLIEQ 257 + +Q L +AQ G I G EML++Q Sbjct: 234 KPTQFLQKAQQQGAIIIDGLEMLVQQ 259