BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0103.p (464 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl0416 [GEPR] COG0477 Permeases of the major facilitator superf... 322 1e-87 STM0212 [GEPR] COG0477 Permeases of the major facilitator superf... 246 6e-65 PA3749 [GEPR] COG0477 Permeases of the major facilitator superfa... 226 6e-59 STM4290 [GEPR] COG0477 Permeases of the major facilitator superf... 220 4e-57 Cj0339 [GEPR] COG0477 Permeases of the major facilitator superfa... 220 4e-57 >Cgl0416 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 467 Score = 322 bits (824), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 178/442 (40%), Positives = 268/442 (60%), Gaps = 11/442 (2%) Query: 2 QSTQSNAHHQQS-----KKAAASGWIGSALEYYDFFIYATAASLIFPQLFFP-KGDPTTA 55 + Q H + + K+AA S WIGSALEYYDF +Y TAA+L+ LFFP P A Sbjct: 3 EQLQGVTHSESTPGKTPKRAALSSWIGSALEYYDFAVYGTAAALVLNHLFFPADTSPGIA 62 Query: 56 IIASLATYGVGYVARPIGAFVLGHLGDTHGRKKVLLWCMFLMGFSTIGVGLLPTYDQVGL 115 I+A++ T GV YV RP+GA ++G LGD +GRK VL+ C+FL+G ST VG LPT+DQVG Sbjct: 63 ILAAMGTVGVAYVVRPLGALIMGPLGDRYGRKFVLMLCLFLIGASTFAVGCLPTFDQVGY 122 Query: 116 WAPALLVIMRLAQGFAVAGEISGASSMILEHSPFGRRGYFSSFTLQGVQAGQILAAAVFL 175 APALLV+ R+ QG + +GE S A S+ LEH+ R + +S+TL G Q G +LA VF+ Sbjct: 123 LAPALLVLCRVIQGLSASGEQSSAISVSLEHADERHRAFTASWTLHGTQFGTLLATGVFI 182 Query: 176 PLAHYMPAEQFNVWGWRIPFLLSFLVIIAGWVIRRTVDETPVFKAADKEELKRRSPVVDA 235 P ++ + WGWR+PF LS V++ ++IRR ++E P F+ + SP+ Sbjct: 183 PFTLFLSEDALMSWGWRVPFWLSAAVVLVAFLIRRGLEEPPAFRENKEAVAGAASPLAMT 242 Query: 236 FRDCSPNMLRVVCMALMNVIPVVATIFGAAYAVQPAYGIGFAKDVYLWIPVVGNIVAVLV 295 R + RV A++N + +V T++ ++A +G + L +PVV N+VA++ Sbjct: 243 LRYHKAAVARVAIAAMINSVNIVFTVWALSFATNI---VGLDRSTVLLVPVVANLVALIA 299 Query: 296 IPYVGKLSDRIGRRPPIIVGSLLAGLFAFAYLYAISIRNVELAFVMSILMWGVVYQGYNA 355 IP G L+DRIGRRP I+G++ GL YL AI N + F M +LM G++Y NA Sbjct: 300 IPLSGMLADRIGRRPVFIMGAIGGGLAMNGYLGAIYSGNWTMIFFMGVLMSGLLYSMGNA 359 Query: 356 VFPSFYPELFPARARVSAMAIAQNLGTAIT-AMLPALFTAVAPPGSSNIWLTVGSIAFAI 414 V+P+FY E+FP RV+ +A+ +G A++ +P + +A+A + W+ V + Sbjct: 360 VWPAFYAEMFPTSVRVTGLALGTQIGFAVSGGFVPVIASALAGD-QGDQWMKVSIFVGVV 418 Query: 415 TIVSALAALSARETYRIPLEKL 436 ++SAL A++A+ET + L+++ Sbjct: 419 CVISALVAMTAKETKALTLDEI 440 >STM0212 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 433 Score = 246 bits (629), Expect = 6e-65, Method: Compositional matrix adjust. Identities = 150/430 (34%), Positives = 227/430 (52%), Gaps = 11/430 (2%) Query: 6 SNAHHQQSKKAAASGWIGSALEYYDFFIYATAASLIFPQLFFPKGDPTTAIIASLATYGV 65 S ++ ++ S WIG+++EYYDF +Y A++L+F LFFP P TA ++S A++GV Sbjct: 2 SGTYNATIRRVVVSAWIGNSIEYYDFLLYGLASALVFGPLFFPGASPLTATLSSFASFGV 61 Query: 66 GYVARPIGAFVLGHLGDTHGRKKVLLWCMFLMGFSTIGVGLLPTYDQVGLWAPALLVIMR 125 G+++RP+GA G+ GDT GRK LL + MG T +G LP+Y +G APALLVI+R Sbjct: 62 GFISRPLGALFFGNRGDTLGRKNTLLITLGGMGAVTFLIGCLPSYASIGALAPALLVILR 121 Query: 126 LAQGFAVAGEISGASSMILEHSPFGRRGYFSSFTLQGVQAGQILAAAVFLPLAHYMPAEQ 185 QGF V GE GA M++E++ RG S+ + G GQ+LA VF+ + +P E Sbjct: 122 FLQGFMVGGEWGGAMLMVVEYAAGKHRGRLSALSQTGGLTGQLLATGVFIVVTQ-LPQEA 180 Query: 186 FNVWGWRIPFLLSFLVIIAGWVIRRTVDETPVFKAADKEEL------KRRSPVVDAFRDC 239 WGWRIPFLLS L+++ G +R +DETPVF+A K++ + PVV R+ Sbjct: 181 LLSWGWRIPFLLSALLVLPGLYMRHRLDETPVFRAFKKQQAINHRQQREERPVVKVVREQ 240 Query: 240 SPNMLRVVCMALMNVIP-VVATIFGAAYAVQPAYGIGFAKDVYLWIPVVGNIVAVLVIPY 298 ++L ++ + +P +AT+F ++A +G A L+I + ++A + Sbjct: 241 WRSILLIIILRFAESVPFFLATVFAVSWATTQ---LGIASLTILYIVMFTCLLAYPMHVL 297 Query: 299 VGKLSDRIGRRPPIIVGSLLAGLFAFAYLYAISIRNVELAFVMSILMWGVVYQGYNAVFP 358 G +SDR G R I G+L AF + + + R++ L + +L+ + + NAV P Sbjct: 298 FGIMSDRRGCRQVYIFGALFVAAMAFPFFWLLESRSLILMTMGYVLLINIGHNSLNAVQP 357 Query: 359 SFYPELFPARARVSAMAIAQNLGTAITAMLPALFTAVAPPGSSNIWLTVGSIAFAITIVS 418 SF+ LF R S +I LG + N W V + S Sbjct: 358 SFFAGLFHPPVRYSGSSIGAQLGAVVAGGFTPFIAKALSAVYDNSWALVAGYVVLTALAS 417 Query: 419 ALAALSARET 428 A AA A ET Sbjct: 418 AFAAKIAPET 427 >PA3749 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 437 Score = 226 bits (577), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 132/375 (35%), Positives = 212/375 (56%), Gaps = 11/375 (2%) Query: 11 QQSKKAAASGWIGSALEYYDFFIYATAASLIFPQLFFPKGDPTTAIIASLATYGVGYVAR 70 + + A + +IG+A+E+YDF++YATAA+L+ +FFP+ T ++++ T+G+ ++AR Sbjct: 16 NSTTRVAVASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSGTAQMLSAFLTFGIAFLAR 75 Query: 71 PIGAFVLGHLGDTHGRKKVLLWCMFLMGFSTIGVGLLPTYDQVGLWAPALLVIMRLAQGF 130 P+G+ + GH GD GRK L+ + LMG ST +G+LP YD +G WAP LL ++R QG Sbjct: 76 PLGSALFGHFGDRIGRKSTLVASLLLMGVSTTLIGVLPGYDSIGYWAPLLLCVLRFGQGL 135 Query: 131 AVAGEISGASSMILEHSPFGRRGYFSSFTLQGVQAGQILAAAVFLPLAHYMPAEQFNVWG 190 + GE GA+ + E++P G+R +F F G G + A +FL LA + EQF WG Sbjct: 136 GLGGEWGGAALLATENAPAGKRAWFGMFPQLGPSIGFLAANGLFLALAMLLSEEQFREWG 195 Query: 191 WRIPFLLSFLVIIAGWVIRRTVDETPVFKAADKEELKRRSPVVDAF-RDCSPNMLRVVCM 249 WRIPFLLS +++ G +R + ETPVF A + + R P+ + F + P +L + M Sbjct: 196 WRIPFLLSAALVVVGLYVRLKLAETPVFAKAMAKHERVRLPIAELFAQHWRPTLLGALAM 255 Query: 250 ALMNVIPVVATIFGAAYAVQPAYGIGFAKDVYLWIPVVGNIVAVLVIPYVGKLSDRIGRR 309 + + ++T+F +Y V +GF+++ +L + + + P LSDR GR+ Sbjct: 256 VVCYALFYISTVFSLSYGVA---SLGFSREEFLGLLCLAVLFMAAATPLSAWLSDRFGRK 312 Query: 310 PPIIVGSLLAGLFAFA---YLYAISIRNVELAFVMSILMWGVVYQGYNAVFPSFYPELFP 366 P +++GSL A FA L S +V L + + + GV + A+ PE+FP Sbjct: 313 PVLLLGSLAAIASGFAMEPLLSQGSTFSVALFLCIELFLMGVTFAPMGALL----PEIFP 368 Query: 367 ARARVSAMAIAQNLG 381 R + + A NLG Sbjct: 369 THVRYTGASAAYNLG 383 >STM4290 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 500 Score = 220 bits (561), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 140/429 (32%), Positives = 232/429 (54%), Gaps = 13/429 (3%) Query: 14 KKAAASGWIGSALEYYDFFIYATAASLIFPQLFFPKGDPTTAIIASLATYGVGYVARPIG 73 +KA + +G+A+E++DF +Y A + ++FFP DP+ +IA+LAT+ V ++ RP+G Sbjct: 24 RKAITAASLGNAMEWFDFGVYGFVAYAL-GKVFFPGADPSVQMIAALATFSVPFLIRPLG 82 Query: 74 AFVLGHLGDTHGRKKVLLWCMFLMGFSTIGVGLLPTYDQVGLWAPALLVIMRLAQGFAVA 133 G LGD +GR+K+L + +M ST +GL+P+Y +G+WAP LL++ ++AQGF+V Sbjct: 83 GLFFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYATIGIWAPILLLLCKMAQGFSVG 142 Query: 134 GEISGASSMILEHSPFGRRGYFSSFTLQGVQAGQILAAAVFLPLAHYMPAEQFNVWGWRI 193 GE +GAS + E+SP +RG+ S+ G AG +L A V + ++ + E F WGWRI Sbjct: 143 GEYTGASIFVAEYSPDRKRGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEENFLEWGWRI 202 Query: 194 PFLLSFLVIIAGWVIRRTVDETPVFKA-ADKEELKRRSPVVD----AFRDCSPNMLR--V 246 PF ++ + I G +R ++ETP F+ DK E R + D +F++ + R + Sbjct: 203 PFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRSLL 262 Query: 247 VCMALMNVIPVVATIFGAAYAVQPAYGIGFAKDVYLWIPVVGNIVAVLVIPYVGKLSDRI 306 C+ L+ V + ++ + +++D + I + I + V P +G LSDR Sbjct: 263 SCIGLVIATNVTYYMLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRF 322 Query: 307 GRRPPIIVGSLLAGLFAFAYLYAISIRNVELAFVMS-ILMWGVVYQGYNAVFPSFYPELF 365 GRRP +I+GS+ LFA A I I + + + + +LM V+ + V S P +F Sbjct: 323 GRRPFVIMGSI--ALFALAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMF 380 Query: 366 PARARVSAMAIAQNLGTAITAMLPALFTAVAPPGSSNIWLTVGSIAFAITIVSALAALSA 425 P R SA+A A N+ I + P L + SS + I ++ + +S Sbjct: 381 PTHIRYSALAAAFNISVLIAGLTPTLAAWLVE--SSQDLMMPAYYLMVIAVIGLITGISM 438 Query: 426 RETYRIPLE 434 +ET PL+ Sbjct: 439 KETANRPLK 447 >Cj0339 [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 453 Score = 220 bits (561), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 132/380 (34%), Positives = 203/380 (53%), Gaps = 10/380 (2%) Query: 14 KKAAASGWIGSALEYYDFFIYATAASLIFPQLFFPKGDPTTAIIASLATYGVGYVARPIG 73 KKA S W+G+A+EY DF +Y AA+ IF ++FFP+ P A++ S TYG+G++ARPIG Sbjct: 24 KKAVFSCWLGTAMEYADFALYGLAAATIFSEVFFPEQTPVIALLLSFVTYGIGFIARPIG 83 Query: 74 AFVLGHLGDTHGRKKVLLWCMFLMGFSTIGVGLLPTYDQVGLWAPALLVIMRLAQGFAVA 133 A GHLGD HGRK V++ + LMG ST +G +P+Y +G+WAP LV +R QGF Sbjct: 84 ALFFGHLGDKHGRKNVMMATIALMGISTTLIGFIPSYAVIGVWAPICLVALRFMQGFGAG 143 Query: 134 GEISGASSMILEHSPFGRRGYFSSFTLQGVQAGQILAAAVFLPLAHYMPAEQFNVWGWRI 193 E+SG + M+ E++P RRG SS G +G +LA+ V+L + M F WGWR+ Sbjct: 144 AELSGGTVMLAEYAPSKRRGLVSSVIALGSNSGTLLASFVWLLMVQ-MDEASFKEWGWRV 202 Query: 194 PFLLSFLVIIAGWVIRRTVDETPVFKAADKEELKRRSPVVDAFRDCSPNMLRVVCMALMN 253 PF+ S L+ + IR V ETPVF+ E +K R + + + A Sbjct: 203 PFMGSILIALFAVYIRFHVKETPVFEKQKNEMMKLRLNNEKHMKKDERSFWQR-SRAFWT 261 Query: 254 VIPVVATIFGAAYAVQPAYGIGFAKDVYLWIP-------VVGNIVAVLVIPYVGKLSDRI 306 ++ + G +Y Q + +G+ + L ++ ++V LVIP G LSD+ Sbjct: 262 MVGLRIGENGPSYLAQ-GFIVGYVTKILLLDKSVATTAVMIASLVGFLVIPLAGYLSDKF 320 Query: 307 GRRPPIIVGSLLAGLFAFAYLYAISIRNVELAFVMSILMWGVVYQGYNAVFPSFYPELFP 366 GR + LL ++AF + +N + + I+ + G V ++ ELF Sbjct: 321 GRCITYRMFCLLLMIYAFPAFMLLDSKNEIIVILTIIVGMSLASLGIFGVQAAWGVELFG 380 Query: 367 ARARVSAMAIAQNLGTAITA 386 + R + MA A+ LG+ ++ Sbjct: 381 VKNRYTKMAFAKELGSILSG 400