BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0093.p (271 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5370 [GEPR] COG0477 Permeases of the major facilitator superfa... 264 2e-70 YPO0465 [GEPR] COG0477 Permeases of the major facilitator superf... 244 2e-64 AGc3904 [GEPR] COG0477 Permeases of the major facilitator superf... 218 9e-57 BMEI0353 [GEPR] COG0477 Permeases of the major facilitator super... 209 5e-54 Cj0250c [GEPR] COG0477 Permeases of the major facilitator superf... 177 2e-44 >PA5370 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 438 Score = 264 bits (675), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 135/266 (50%), Positives = 179/266 (67%) Query: 2 GSLTAGITGGILLGSLMGIFINSAFEPGEVAGYAWRIPFILGGVFGLVSVYLRRYLEETP 61 G+LT+G+T GILLGSL+ INS + EV YAWRIPF+LGGVFGL SVYLRR+L ETP Sbjct: 163 GTLTSGLTAGILLGSLVATAINSFYSATEVQDYAWRIPFLLGGVFGLFSVYLRRWLHETP 222 Query: 62 VFRELAARRKEANELPLKTVLREHRAASVLTAGMTWCLSGAVVVVILMTPSYLQTVHHLS 121 VF EL R+ A E+PLK V+R+HR A +++ +TW LS A+VVVILMTP+ LQ+V+ Sbjct: 223 VFAELQQRKALAEEVPLKAVVRDHRGAVLVSMLLTWVLSAAIVVVILMTPTVLQSVYGFD 282 Query: 122 PKLVMQANCAGTLMLTIGCLAIGWLCDRIGTRASMIIGWGGLGLSTWWFYGQLPGSPESL 181 ++AN + LT+GC+ G + DR G + + G L L +W FYG L P+ L Sbjct: 283 AATALKANSLAIVCLTLGCIVAGRMADRYGAGLTFVAGSVLLALVSWSFYGNLKAHPDWL 342 Query: 182 VWGYALVGLFVGSISLTPIVSTRAFPPPVRFTGLSFAYNMAYAVFGGLTPVLISLWIKAD 241 YAL G FVG + P V AFPP VRF+GLSF+YN+AYA+FGGLTP+ ++L +K Sbjct: 343 FPLYALTGFFVGIVGAVPYVMVNAFPPVVRFSGLSFSYNLAYAIFGGLTPMAVALLLKQS 402 Query: 242 PQGPALYVIGLSILGVLLAFVPMSSK 267 P GPA YV+ L ++G L+ ++ K Sbjct: 403 PMGPAYYVVTLCLVGFLVGLYLLAQK 428 >YPO0465 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 462 Score = 244 bits (622), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 120/248 (48%), Positives = 164/248 (66%) Query: 2 GSLTAGITGGILLGSLMGIFINSAFEPGEVAGYAWRIPFILGGVFGLVSVYLRRYLEETP 61 G+LTAG+T GILLGSL+ +N+ + WRIPF LGG+FGL ++YLRR+L+ETP Sbjct: 180 GTLTAGLTAGILLGSLVATVMNTTLGHQAILEGGWRIPFFLGGIFGLFAMYLRRWLQETP 239 Query: 62 VFRELAARRKEANELPLKTVLREHRAASVLTAGMTWCLSGAVVVVILMTPSYLQTVHHLS 121 +F+E+ AR+ A ELPLK+V+ H+ V++ +TW LS +VVVILMTP+YLQ ++ Sbjct: 240 IFKEMQARKTLAEELPLKSVVVNHKKEVVVSMLLTWLLSAGIVVVILMTPTYLQKQFNVP 299 Query: 122 PKLVMQANCAGTLMLTIGCLAIGWLCDRIGTRASMIIGWGGLGLSTWWFYGQLPGSPESL 181 P+L +QAN + L IGC+ G DR G + I+G L +STW FY +P L Sbjct: 300 PELALQANSLAIIALVIGCVVAGLAIDRFGASKTFIVGSLMLAMSTWSFYHTNLTNPSQL 359 Query: 182 VWGYALVGLFVGSISLTPIVSTRAFPPPVRFTGLSFAYNMAYAVFGGLTPVLISLWIKAD 241 Y L G VG + P V RAFP VRFTG+SF+YN+AYA+FGGLTP+L++LW+K+ Sbjct: 360 FPHYMLAGFCVGIVGAVPYVMVRAFPAEVRFTGISFSYNVAYAIFGGLTPILVTLWMKSS 419 Query: 242 PQGPALYV 249 PA Y+ Sbjct: 420 AMAPAYYM 427 >AGc3904 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 443 Score = 218 bits (556), Expect = 9e-57, Method: Compositional matrix adjust. Identities = 114/254 (44%), Positives = 165/254 (64%) Query: 2 GSLTAGITGGILLGSLMGIFINSAFEPGEVAGYAWRIPFILGGVFGLVSVYLRRYLEETP 61 G LT+G++ GI+LGSL+ INS F P +VAGYAWRIPF+LGGVFGL++VYLRR+LEETP Sbjct: 161 GFLTSGLSFGIMLGSLIAFAINSLFTPEDVAGYAWRIPFLLGGVFGLIAVYLRRWLEETP 220 Query: 62 VFRELAARRKEANELPLKTVLREHRAASVLTAGMTWCLSGAVVVVILMTPSYLQTVHHLS 121 ++ E+ + ++LPL VL+ HR +++A +TW LS A+VV LMT ++LQ ++ + Sbjct: 221 IYMEMKKSKSLTDKLPLGLVLKHHRRGVIISALLTWVLSAAIVVTTLMTATFLQKLYGYT 280 Query: 122 PKLVMQANCAGTLMLTIGCLAIGWLCDRIGTRASMIIGWGGLGLSTWWFYGQLPGSPESL 181 P + GTL L G + G L DR+G+ + G++T+ FY S E++ Sbjct: 281 PTQALAGTSFGTLFLIFGVIIAGALIDRVGSGIFFMGASIFFGIATFTFYSYAGTSLETM 340 Query: 182 VWGYALVGLFVGSISLTPIVSTRAFPPPVRFTGLSFAYNMAYAVFGGLTPVLISLWIKAD 241 Y ++GL VG P V RAFP VRF+GLSFAYN++YAVFGGLTP+ ++ + + Sbjct: 341 FVLYGVMGLSVGMAGAVPYVMVRAFPASVRFSGLSFAYNVSYAVFGGLTPIGVTTALAIN 400 Query: 242 PQGPALYVIGLSIL 255 P A Y++ ++ L Sbjct: 401 PMAHAWYLVFIAFL 414 >BMEI0353 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 503 Score = 209 bits (532), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 112/254 (44%), Positives = 163/254 (64%) Query: 2 GSLTAGITGGILLGSLMGIFINSAFEPGEVAGYAWRIPFILGGVFGLVSVYLRRYLEETP 61 G L +G+T GI++GSL+ IN F P E++ YAWRIPF +GG+FGL++VYLRR+L ETP Sbjct: 216 GFLCSGLTLGIMIGSLIATAINWIFTPEELSAYAWRIPFFIGGIFGLLAVYLRRWLAETP 275 Query: 62 VFRELAARRKEANELPLKTVLREHRAASVLTAGMTWCLSGAVVVVILMTPSYLQTVHHLS 121 +F E+ R ++LPL TVLR H V++ +TW LS +VV LMT ++LQ ++ + Sbjct: 276 IFTEMKNSRLLKDKLPLGTVLRNHMHGVVISVLLTWILSAGIVVTTLMTATFLQKLYGYT 335 Query: 122 PKLVMQANCAGTLMLTIGCLAIGWLCDRIGTRASMIIGWGGLGLSTWWFYGQLPGSPESL 181 P + A GTL L G ++ G + DRIG+ + G++T+ FY S L Sbjct: 336 PLQSLAATSFGTLFLMFGTVSAGAIVDRIGSGRFFAVAGIFFGVATFVFYTYAAVSLPVL 395 Query: 182 VWGYALVGLFVGSISLTPIVSTRAFPPPVRFTGLSFAYNMAYAVFGGLTPVLISLWIKAD 241 YA++GL VG + P V RAFP PVRF+GLSF+YN++YAVFGGLTPV+++ + + Sbjct: 396 FALYAVMGLSVGMVGAAPYVMVRAFPAPVRFSGLSFSYNVSYAVFGGLTPVIVTSLLAVN 455 Query: 242 PQGPALYVIGLSIL 255 P A Y++ +++L Sbjct: 456 PMAHAWYLVFIAVL 469 >Cj0250c [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 436 Score = 177 bits (449), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 98/274 (35%), Positives = 161/274 (58%), Gaps = 14/274 (5%) Query: 1 VGSLTAGITGGILLGSLMGIFINSAFEPGEVAGYAWRIPFILGGVFGLVSVYLRRYLEET 60 +G LTA + GGILLGSL+ + +N + E+ +AWRIPF LGG+FG++S YLR++L ET Sbjct: 152 LGILTASVVGGILLGSLVFLIMNKIYTQEELHEWAWRIPFFLGGIFGIISAYLRKFLRET 211 Query: 61 PVFRELAARRKEANELPLKTVLREHRAASVLTAGMTWCLSGAVVVVILMTPSYLQTVHHL 120 PVF ++ + K + PLK V ++ + VL+ +TW L+G +VV+IL+ PSY+ + + Sbjct: 212 PVFEQM-KKDKALEKFPLKEVFKKAKMGIVLSMMITWVLTGCIVVMILLMPSYMAKILQI 270 Query: 121 SPKLVMQANCAGTLMLTIGCLAIGWLCDRIGTRASMIIGWGGLGLSTWWFYGQL--PGSP 178 + + G L++ +GC+ G L D+IG S + G+++ ++ L + Sbjct: 271 NTSIQTYLQIGGILLICLGCIISGILADKIGVIKSCVFFSVFFGIASLLYFNTLYRQNAD 330 Query: 179 ESLVWG-YALVGLFVGSISLTPIVSTRAFPPPVRFTGLSFAYNMAYAVFGGLTPVLISLW 237 +LV Y LV F G ++ P++ + F ++F+GLSF+YN+AYA+ GGLTP L + + Sbjct: 331 FNLVACLYLLVCFFSGVMNFCPLIMSEVFDAKIKFSGLSFSYNIAYAIAGGLTPQL-AFF 389 Query: 238 IKADPQGP---------ALYVIGLSILGVLLAFV 262 + + LYV L+I+ +L AF+ Sbjct: 390 LHSFALNNLSNFWRFSLGLYVFFLAIIALLCAFI 423