BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0078.p (448 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2572 [KT] COG3437 Response regulator containing a CheY-like re... 249 7e-66 VC1087 [KT] COG3437 Response regulator containing a CheY-like re... 244 3e-64 PA2881 [T] COG0784 FOG Pae Pseudomonas aeruginosa 109 2e-23 alr5251 [T] COG0784 FOG Nos Nostoc sp. PCC 7120 109 2e-23 TM0186 [KT] COG3437 Response regulator containing a CheY-like re... 107 6e-23 >PA2572 [KT] COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain Pae Pseudomonas aeruginosa Length = 447 Score = 249 bits (637), Expect = 7e-66, Method: Compositional matrix adjust. Identities = 165/420 (39%), Positives = 246/420 (58%), Gaps = 11/420 (2%) Query: 25 VLLVDDEQSILSALKRTFRPQGYRLIMATSAEAALEMMAASEVDLVISDMRMPGMNGAQF 84 VLLVDDE ILS+L+R R Q Y L++A S E AL+++ + VDLV+SD RMP M+GA Sbjct: 17 VLLVDDEPLILSSLRRLLRNQPYDLLLAESGEQALQLLESRPVDLVVSDARMPNMDGAAL 76 Query: 85 LAKVRQQWPSTMRILLTGYSEIGSTISAINDGGINHYLSKPWDDRELLLIVAHALEEQQL 144 LA++ ++ P T+RILLTG++++ + AIN+G I+HYLSKPW+D ELLL + +LE Sbjct: 77 LAEIHRRSPETIRILLTGHADLPTIAKAINEGRIHHYLSKPWNDDELLLTLRQSLEYLHS 136 Query: 145 RKQKMALERKVREQNLQLADFNRQLERQVQSRTEELRQTVMFLESAQEEEQKSFLSMLRV 204 +++ LER +EQN +L N LE++VQ+RT EL+QT L+ A EE ++S++ V Sbjct: 137 ERERRRLERLTQEQNDRLQQLNATLEKRVQARTAELQQTADMLDLAYEELKRSYVVGTEV 196 Query: 205 FSDISELR---AGLATGQSARVARWCEQLALRMGMTTHHARDTMMAGMLHGIGKLELPDE 261 FS + R Q + R C L + RD MA L+ IGKL D Sbjct: 197 FSLLVNQRLPKDKQTNQQIIELVRACCASGL---VDESDGRDLAMAAALYNIGKLSWNDT 253 Query: 262 LVRKPIEKMNSDEVQRFLWHPVRGQMLLTPIPSLAESGEIIRHQHERYDGRGVPESLSGD 321 L+ P + + + RF +P + LL + + ++ +IRH E +DG G P+ L G+ Sbjct: 254 LLSSPSDLLYHHDRDRFRGYPELSESLLMSLEPMQDAARLIRHHQEHWDGSGYPDHLKGE 313 Query: 322 AIPLGARILAVVRDFEGLCNGGITSLNASPEKALSMLRAHAGHRYDPLVVESFI----AM 377 AIPLG+R+L + DF L G I + ++AL +R +AG YDP ++E FI Sbjct: 314 AIPLGSRLLKLAVDFVELQRGLILERRMNRDEALMYIRKYAGRLYDPELIEPFIQVCATT 373 Query: 378 MEEQQMALEQQTRLLATQELRVGMKLAEDLRTKSGVLLLNKDHVLDDALLARLRRFEQLD 437 + + +A + Q R T++L GM LA +L +G+LLLN VL+ AL+ +L FE ++ Sbjct: 374 LADVTLA-DPQVRAHGTRDLVPGMVLARNLTANNGMLLLNAGKVLNLALIEKLIAFEAIE 432 >VC1087 [KT] COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain Vch Vibrio cholerae Length = 447 Score = 244 bits (623), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 150/436 (34%), Positives = 236/436 (54%), Gaps = 17/436 (3%) Query: 25 VLLVDDEQSILSALKRTFRPQGYRLIMATSAEAALEMMAASEVDLVISDMRMPGMNGAQF 84 VLL+DDE IL AL R R Y ++ + ALE + + + ++ISDMRMP M+GA F Sbjct: 13 VLLLDDENDILKALNRVLR-MDYNVVTFDNGADALEYLQENPIHIIISDMRMPEMDGADF 71 Query: 85 LAKVRQQWPSTMRILLTGYSEIGSTISAINDGGINHYLSKPWDDRELLLIVAHALEEQQL 144 LAK R+ P T+R+LLTGY++I ST+ A+N GGI+ Y+SKPWD+ L LIV A E +L Sbjct: 72 LAKAREMQPDTVRLLLTGYADIQSTVRAVNAGGIHTYISKPWDNENLKLIVGKAAEFYRL 131 Query: 145 R--KQKMALERKVR------------EQNLQLADFNRQLERQVQSRTEELRQTVMFLESA 190 K+++ +E + R E N +LA FN++LE +VQ RT L+++ LES Sbjct: 132 SRDKERLTIELEERNKELEVANQALAENNHKLAQFNQELEAKVQERTVALQESNKRLESL 191 Query: 191 QEEEQKSFLSMLRVFSDISELRAGLATGQSARVARWCEQLALRMGMTTHHARDTMMAGML 250 K+F +L + + I + R G + R+A + +AL++ ++ A + G++ Sbjct: 192 LASRNKTFKDILAMVTAIIQHRTGFPADHAERIANQAKSVALKLKLSEAVASHVYLCGLM 251 Query: 251 HGIGKL-ELPDELVRKPIEKMNSDEVQRFLWHPVRGQMLLTPIPSLAESGEIIRHQHERY 309 H IG + E ++ + + + + + +P+ G ++ I EIIRHQ E Y Sbjct: 252 HQIGLIAETSNDWKVVKVHQDSEIPITPNV-NPILGAEIVGRIKRFEPLMEIIRHQDELY 310 Query: 310 DGRGVPESLSGDAIPLGARILAVVRDFEGLCNGGITSLNASPEKALSMLRAHAGHRYDPL 369 DG G P+ L G+ IP+GARI+ VV+D++ G + A LR + YDP Sbjct: 311 DGTGKPDHLRGEQIPIGARIIKVVKDYDFFVAGANNPRRMHTKSAQGYLRQQSEVYYDPK 370 Query: 370 VVESFIAMMEEQQMALEQQTRLLATQELRVGMKLAEDLRTKSGVLLLNKDHVLDDALLAR 429 VVE+FI ++ E ++ E+R GM + D+ +G L+L + + + LL + Sbjct: 371 VVEAFITIVSAVTRIEEGMELCVSLSEVRPGMVIKRDIYLPNGNLMLTAGNAMSEPLLRK 430 Query: 430 LRRFEQLDEMPLKARI 445 L+ EQ MP+ I Sbjct: 431 LKELEQEMNMPIPVYI 446 >PA2881 [T] COG0784 FOG Pae Pseudomonas aeruginosa Length = 303 Score = 109 bits (272), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 51/121 (42%), Positives = 80/121 (66%), Gaps = 2/121 (1%) Query: 21 PPPC-VLLVDDEQSILSALKRTFRPQGYRLIMATSAEAALEMMAASEVDLVISDMRMPGM 79 P P +L VDDE+ IL +L FR + Y ++ + ALE + + +++SD RMP M Sbjct: 3 PSPVRILFVDDEERILRSLAMQFR-RHYEVLTESDPRRALERLKTERIQVLVSDQRMPQM 61 Query: 80 NGAQFLAKVRQQWPSTMRILLTGYSEIGSTISAINDGGINHYLSKPWDDRELLLIVAHAL 139 +GA+ LA+ R+++P T+RILLTGYS++ + + A+NDGGI YL+KPW+ +E+ + A Sbjct: 62 SGAELLAQARERYPETLRILLTGYSDLDAAVDALNDGGIFRYLTKPWNPQEMAFTLRQAA 121 Query: 140 E 140 E Sbjct: 122 E 122 >alr5251 [T] COG0784 FOG Nos Nostoc sp. PCC 7120 Length = 315 Score = 109 bits (272), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 60/140 (42%), Positives = 89/140 (63%), Gaps = 5/140 (3%) Query: 25 VLLVDDEQSILSALKRTFRPQGYRLIMATSAEAALEMMAA-SEVDLVISDMRMPGMNGAQ 83 +L+VDDE L L RTFR + + ++ A S +ALE++AA EV ++ISD RMP M G + Sbjct: 26 ILVVDDEPDNLDLLYRTFR-RDFNVLKADSGLSALEVLAAEGEVAVIISDQRMPEMKGTE 84 Query: 84 FLAKVRQQWPSTMRILLTGYSEIGSTISAINDGGINHYLSKPWDDRELLLIVAHALEEQQ 143 FL+K Q+P T+RI+LTG+++I + AIN G + Y++KPWD EL +V A E Sbjct: 85 FLSKTVPQFPDTVRIILTGFTDIEDLVEAINAGQVYKYITKPWDPGELKAVVQRAAETYD 144 Query: 144 LRKQKMALERKVREQNLQLA 163 L KQ+ ++R N Q++ Sbjct: 145 LLKQRT---EELRRANAQMS 161 >TM0186 [KT] COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain Tma Thermotoga maritima Length = 368 Score = 107 bits (267), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 96/364 (26%), Positives = 166/364 (45%), Gaps = 37/364 (10%) Query: 24 CVLLVDDEQSILSALKRTFRPQGYRLIMATSAEAALEMMAASEVDLVISDMRMPGMNGAQ 83 VL+V+D+ A+ + + G+ +I A + E A+E+ + VD+ + D+ +PGM+G + Sbjct: 2 TVLIVEDDDITREAMGQYLKLSGFNVIEAENGEKAVEL--SENVDVALVDVMLPGMSGIE 59 Query: 84 FLAKVRQQWPSTMRILLTGYSEIGSTISAINDGGINHYLSKPWDDRELLLIVAHALEEQQ 143 + K++ + PS + ++T Y + + + G + ++ KP + L L + HAL Sbjct: 60 VVNKIKAKNPSCVVFVVTAYDDT-EIVKKCVEAGADDFIKKPVNLELLRLKITHALR--- 115 Query: 144 LRKQKMALERKVREQNLQLADFNRQLERQVQSRTEELRQTVMFLESAQEE---EQKSFL- 199 NR S + L++ + LE EE E + FL Sbjct: 116 ----------------------NRVFHMYRNSYLKSLKKKLFLLEKTAEEFFTEYEDFLF 153 Query: 200 SMLRVFSDISELRAGLATGQSARVARWCEQLALRMGMTTHHARDTMMAGMLHGIGKLELP 259 +L + + +SE R + RV ++A MGM+ + A LH IGK+ +P Sbjct: 154 EVLEILNMLSEYRDMETHRHTERVGWLSGRIAEEMGMSEVFVTEIQFAAPLHDIGKIGIP 213 Query: 260 DELVRKPIEKMNSDEVQRFLWHPVRGQMLL--TPIPSLAESGEIIRHQHERYDGRGVPES 317 D ++ KP + +E + H G +L + P L EI HER+DG G P Sbjct: 214 DRILLKP-GILTPEEFEIMKQHTTIGFRILSRSNSPILQLGAEIALTHHERWDGSGYPRG 272 Query: 318 LSGDAIPLGARILAVVRDFEGLCNGGITSLNASP-EKALSMLRAHAGHRYDPLVVESFIA 376 L IP+ I+AV F+ + + N P E+A + + +G Y P VVE+F+ Sbjct: 273 LKEREIPISGLIVAVADSFDAMVSRRPYK-NPKPLEEAFREIESLSGKLYSPEVVEAFLK 331 Query: 377 MMEE 380 + +E Sbjct: 332 LEKE 335