BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0073.p (403 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value alr2279_3 [T] COG0642 Signal transduction histidine kinase Nos N... 188 2e-47 PA3462_2 [T] COG0642 Signal transduction histidine kinase Pae Ps... 187 4e-47 MA2013_2 [T] COG0642 Signal transduction histidine kinase Mac Me... 182 9e-46 VC1349_3 [T] COG0642 Signal transduction histidine kinase Vch Vi... 179 1e-44 sll1905_3 [T] COG0642 Signal transduction histidine kinase Syn S... 178 2e-44 >alr2279_3 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 260 Score = 188 bits (477), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 96/212 (45%), Positives = 141/212 (66%), Gaps = 3/212 (1%) Query: 1 MNGILGLSELLMESGLSSKQRDYADSIHGATGGLVRIINDILDFSKIESGKLDLEMVAFH 60 MN I+G+S LL+++ L +Q DY ++I ++ L+ IINDILDFSKIESGKL+LE F Sbjct: 27 MNAIIGMSGLLLDTTLKPEQFDYVETIRNSSHTLLTIINDILDFSKIESGKLELEEQPFD 86 Query: 61 PVRLVQELSDLYRPSLQRKDVQFDLHLDCPENLSVVGDPARLKQVLGNLLSNAIKFTQAG 120 V+E DL P K ++ L+ VVGD R++Q+L NL+SNA+KFT+ G Sbjct: 87 LRLCVEEALDLLAPQAASKGIELMYQLEPDTPTLVVGDITRIRQILWNLVSNAVKFTKIG 146 Query: 121 HVQLSMSARQ---DESGPSRWRLFFAITDTGIGISPEALQQLFRPFAQADSSISRRFGGT 177 + +++ A+Q ++ P+R+ FA+ DTGIGI + L +LF+PF+Q D+S++RR+GGT Sbjct: 147 EICITIGAKQKIYKQTDPTRYEFQFAVQDTGIGIERDRLHRLFKPFSQVDASMTRRYGGT 206 Query: 178 GLGLAISKNLVELMGGTIACQSIPGESTRFSF 209 GLGLAISK L E+MGG + +S + + F F Sbjct: 207 GLGLAISKRLSEIMGGKMWVESQSHQGSIFYF 238 >PA3462_2 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 385 Score = 187 bits (475), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 101/213 (47%), Positives = 141/213 (66%), Gaps = 6/213 (2%) Query: 1 MNGILGLSELLMESGLSSKQRDYADSIHGATGGLVRIINDILDFSKIESGKLDLEMVAFH 60 +NG+LG+ +LL ++ L Q Y ++I + L+ +INDILD+++IESGKL LE + F Sbjct: 17 LNGVLGMLQLLRDTPLDRGQAAYVETIASSGSALMSVINDILDYARIESGKLHLERIDFD 76 Query: 61 PVRLVQELSDLYRPSLQRKDVQFDLHLD--CPENLSVVGDPARLKQVLGNLLSNAIKFTQ 118 L+ + L+ K + L LD P L+ GDP RL+QVL NLLSNA+KFT Sbjct: 77 LEELLSDTLALFSAQAVEKRLHLHLGLDRGVPRRLN--GDPTRLRQVLMNLLSNALKFTA 134 Query: 119 AGHVQLSMSARQDESGPSRWRLFFAITDTGIGISPEALQQLFRPFAQADSSISRRFGGTG 178 GHV + + R DE G R RL ++++D+GIGIS +A + LF F+QADSS +RR+GG+G Sbjct: 135 EGHVAVRVQRRFDEGG--RERLLYSVSDSGIGISAQAQKTLFESFSQADSSTTRRYGGSG 192 Query: 179 LGLAISKNLVELMGGTIACQSIPGESTRFSFEL 211 LGLAIS+ LV++MGG I S PG+ TRFS +L Sbjct: 193 LGLAISRELVQMMGGRIEVSSEPGKGTRFSVDL 225 >MA2013_2 [T] COG0642 Signal transduction histidine kinase Mac Methanosarcina acetivorans str.C2A Length = 296 Score = 182 bits (463), Expect = 9e-46, Method: Compositional matrix adjust. Identities = 95/218 (43%), Positives = 132/218 (60%), Gaps = 9/218 (4%) Query: 1 MNGILGLSELLMESGLSSKQRDYADSIHGATGGLVRIINDILDFSKIESGKLDLEMVAFH 60 MN +LG+ E+L+E+ L+ +QR+Y H + L+ II+D+LDFSKIE KL+LE ++F Sbjct: 36 MNAVLGMLEMLLETSLTDEQREYLQLAHASAESLLSIIDDVLDFSKIEQNKLELEQISFE 95 Query: 61 PVRLVQELSDLYRPSLQRKDVQFDLHLDCPENLSVVGDPARLKQVLGNLLSNAIKFTQAG 120 L+ + +L K ++ H++ + +GDP RLKQVL N+L NAIKFT+ G Sbjct: 96 LESLISHIINLLSGKAGSKGLKLAFHIEKDLPSTFIGDPVRLKQVLFNILGNAIKFTKKG 155 Query: 121 HVQLSM---------SARQDESGPSRWRLFFAITDTGIGISPEALQQLFRPFAQADSSIS 171 + LS+ S + P L F + DTGIGI PE L Q+F PF QAD+S++ Sbjct: 156 EIALSVEVYMPSERNSGLSNSDFPEEVALLFKVKDTGIGIPPEKLSQIFDPFIQADASVT 215 Query: 172 RRFGGTGLGLAISKNLVELMGGTIACQSIPGESTRFSF 209 R +GGTGLGLAIS LVELM G I +S G+ F F Sbjct: 216 REYGGTGLGLAISSQLVELMEGRIWVESEVGKGCTFYF 253 >VC1349_3 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 260 Score = 179 bits (453), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 94/214 (43%), Positives = 136/214 (63%), Gaps = 2/214 (0%) Query: 1 MNGILGLSELLMESGLSSKQRDYADSIHGATGGLVRIINDILDFSKIESGKLDLEMVAFH 60 MN ILG++ L + + L + QR Y I+ + L+ IINDILDFSK+E+GKL++E + F+ Sbjct: 32 MNAILGMAHLALNTPLDTTQRKYVTRINESAKNLLGIINDILDFSKMEAGKLNVERIDFN 91 Query: 61 PVRLVQELSDLYRPSLQRKDVQFDLHLDCPENLSVVGDPARLKQVLGNLLSNAIKFTQAG 120 ++ ++ + Q K ++F + +D L ++GDP RL QV+ NL NA+KFT G Sbjct: 92 LDDVLDNVTAVVSLKAQEKGIEFLMDIDPHIPLGLIGDPLRLGQVMVNLCGNAVKFTSQG 151 Query: 121 HVQLSMSARQDESGPSRWRLFFAITDTGIGISPEALQQLFRPFAQADSSISRRFGGTGLG 180 + L SAR + + L FA+ DTGIGI+ + L LF F+QAD+SI+R++GGTGLG Sbjct: 152 EIVL--SARVSQLNEQQVTLRFAVKDTGIGIAQDKLDDLFDAFSQADNSITRQYGGTGLG 209 Query: 181 LAISKNLVELMGGTIACQSIPGESTRFSFELGCA 214 L+ISK LVELMGG I S G+ + F F + C Sbjct: 210 LSISKQLVELMGGQITVHSEEGKGSTFEFSVVCG 243 >sll1905_3 [T] COG0642 Signal transduction histidine kinase Syn Synechocystis Length = 270 Score = 178 bits (452), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 90/199 (45%), Positives = 136/199 (68%) Query: 1 MNGILGLSELLMESGLSSKQRDYADSIHGATGGLVRIINDILDFSKIESGKLDLEMVAFH 60 MN I+G++ LL+++ L+++Q+ +A +I + L+ +INDILDFSKIE+GKLDLE+ F Sbjct: 36 MNAIIGMTGLLLDTDLTTQQKYFAQTIRNSGETLLTLINDILDFSKIEAGKLDLEVYPFD 95 Query: 61 PVRLVQELSDLYRPSLQRKDVQFDLHLDCPENLSVVGDPARLKQVLGNLLSNAIKFTQAG 120 + ++E D+ PS ++K + P ++ GD RL+Q+L NLLSNA+KFT+AG Sbjct: 96 LGQCLEEALDVVVPSARQKSLTLIRRFLTPIPPNLQGDVTRLRQILVNLLSNAVKFTEAG 155 Query: 121 HVQLSMSARQDESGPSRWRLFFAITDTGIGISPEALQQLFRPFAQADSSISRRFGGTGLG 180 V++++ ++ +++ FA+ DTGIGI+P Q LF+ F+Q +SSI+RRFGGTGLG Sbjct: 156 QVKVTVEVVDHDAAKGEYQICFAVQDTGIGIAPNQQQALFQAFSQGNSSITRRFGGTGLG 215 Query: 181 LAISKNLVELMGGTIACQS 199 LAI L LMGGTI +S Sbjct: 216 LAICVRLTALMGGTIWAES 234