BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0490.p (388 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1417 [M] COG0763 Lipid A disaccharide synthetase Rso Ralstoni... 351 1e-96 PA3643 [M] COG0763 Lipid A disaccharide synthetase Pae Pseudomon... 309 9e-84 NMB0199 [M] COG0763 Lipid A disaccharide synthetase Nme Neisseri... 304 2e-82 NMA0069 [M] COG0763 Lipid A disaccharide synthetase NmA Neisseri... 300 4e-81 PM1997 [M] COG0763 Lipid A disaccharide synthetase Pmu Pasteurel... 288 2e-77 >RSc1417 [M] COG0763 Lipid A disaccharide synthetase Rso Ralstonia solanacearum Length = 390 Score = 351 bits (901), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 192/377 (50%), Positives = 247/377 (65%), Gaps = 7/377 (1%) Query: 13 IALVAGESSGDLLGSRLLAGVRERLP-EVRLHGIGGEHMMAQGFTSDWPMDKLTVRGLFE 71 I + AGE+SGDLL S LL G+ RLP +V GIGG M QGF S WPM KL+V G E Sbjct: 12 IGMAAGEASGDLLASLLLKGLHARLPRDVAYEGIGGARMAEQGFASHWPMHKLSVNGYVE 71 Query: 72 VIPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIPTIHFIGPQIWA 131 V+ + REI I+ L+ LLAD P F+GVD P FN +E +++AG+P +HF+ P IWA Sbjct: 72 VLGQLREILAIRRELKQNLLADPPMAFIGVDAPDFNFNVEIAMRRAGVPVVHFVSPSIWA 131 Query: 132 WRGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQPDTMVARQRLSL 191 WR RIK I RAV H+L +FPFE IY +AG+P TYVGHPLA+ IPL+PD AR RL L Sbjct: 132 WRAGRIKTIARAVDHILCLFPFEPEIYARAGIPATYVGHPLADEIPLEPDVEGARSRLGL 191 Query: 192 NGPGRVVAILPGSRMSELKQNGAGFLAAARLLKQRDAQLQFVTPMAGDRQMAAFQEQI-- 249 +VVA+LPGSR SE+K G AA ++ + L FV P A A +E+I Sbjct: 192 PLGRKVVAVLPGSRNSEVKLLGPTLFAAMARMQAVEPDLAFVLPAAN----AMLRERIDA 247 Query: 250 RQGGYEDLDISVIRGQSHSAMEAADAVLVASGTASLEVALYKKPMVISYKVNWASYQIMR 309 + + L + V+ GQSH+AMEAAD +L+ASGTA+LE ALYKKPMVI+YKV W + QIM+ Sbjct: 248 MRAEHPGLHLWVVDGQSHAAMEAADVILLASGTATLEAALYKKPMVITYKVPWLTAQIMK 307 Query: 310 HMAYQPWVGLPNILAREFLVPELLQNQATPQALADAMWFQLEDHAHQQRLARRFADMHQS 369 Y P+VGLPNIL+ F+VPELLQ+ ATP+ALA QL DHA+ L F MH + Sbjct: 308 RKGYLPYVGLPNILSGRFVVPELLQDDATPEALARETLLQLSDHANAAFLREHFTQMHLT 367 Query: 370 LLRDTSRESANAVCEVI 386 L ++ + A V +++ Sbjct: 368 LKQNMADIGAQVVVDLL 384 >PA3643 [M] COG0763 Lipid A disaccharide synthetase Pae Pseudomonas aeruginosa Length = 378 Score = 309 bits (791), Expect = 9e-84, Method: Compositional matrix adjust. Identities = 174/377 (46%), Positives = 250/377 (66%), Gaps = 11/377 (2%) Query: 13 IALVAGESSGDLLGSRLLAGVRERLPEVRLHGIGGEHMMAQGFTSDWPMDKLTVRGLFEV 72 +ALVAGE+SGD+LGS L+ +R R P++ G+GG M A+G +S +PM++L+V GL EV Sbjct: 7 VALVAGEASGDILGSGLMQALRARHPDIEFIGVGGPRMEAEGLSSYFPMERLSVMGLVEV 66 Query: 73 IPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIPTIHFIGPQIWAW 132 + R E+ + L L+ RPDV +G+D P F LG+E +L++AG+ T+H++ P +WAW Sbjct: 67 LGRLPELLRRRKRLIRTLIEARPDVMIGIDAPDFTLGVEHKLRQAGLRTVHYVSPSVWAW 126 Query: 133 RGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQPDTMVARQRLSLN 192 R R+ KI+ A ML +FPFE Y + GVPV +VGHPLA IPLQ D AR RL L Sbjct: 127 RQKRVLKIREACDLMLALFPFEARFYEEHGVPVRFVGHPLANTIPLQADRAAARARLGLP 186 Query: 193 GPGRVVAILPGSRMSELKQNGAGFL-AAARLLKQRDAQLQFVTPMAGDRQMAAFQEQIRQ 251 G+V+A++PGSR E+ + GA FL A RLL +R L+FV P A AA +EQI Q Sbjct: 187 ADGQVLALMPGSRGGEVGKLGALFLDTAQRLLVERPG-LRFVLPCAS----AARREQIEQ 241 Query: 252 --GGYEDLDISVIRGQSHSAMEAADAVLVASGTASLEVALYKKPMVISYKVNWASYQIMR 309 G E L ++++ G SH A+ A DAVL+ASGTA+LE LYK+PMV++Y+V +Y+I++ Sbjct: 242 MLQGREPLPLTLLDGASHEALAACDAVLIASGTATLEALLYKRPMVVAYRVAGLTYRILK 301 Query: 310 HMAYQPWVGLPNILAREFLVPELLQNQATPQALADAMWFQLEDHAHQQRLARRFADMHQS 369 + P++ LPN+LA LVPEL+Q+ ATPQALA + L+D + Q F +H++ Sbjct: 302 RLVKSPYISLPNLLAGRLLVPELIQDAATPQALAATLSPLLDDGSQQVEF---FDAIHRA 358 Query: 370 LLRDTSRESANAVCEVI 386 L +D S ++A AV +++ Sbjct: 359 LRQDASAQAAEAVLQLV 375 >NMB0199 [M] COG0763 Lipid A disaccharide synthetase Nme Neisseria meningitidis MC58 Length = 390 Score = 304 bits (779), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 166/378 (43%), Positives = 236/378 (62%), Gaps = 4/378 (1%) Query: 13 IALVAGESSGDLLGSRLLAGVRERLPEVRLHGIGGEHMMAQGFTSDWPMDKLTVRGLFEV 72 IA+ GE+SGDLLG+ L+ +R+R P+ R GIGGE M A+GF S + ++L VRG EV Sbjct: 15 IAVSVGEASGDLLGAHLIRAIRKRCPQARFTGIGGELMKAEGFESLYDQERLAVRGFVEV 74 Query: 73 IPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIPTIHFIGPQIWAW 132 + R EI I+ L LL+ +PDVFVG+D P FNLG+ E+LK++GIPT+H++ P +WAW Sbjct: 75 VRRLPEILRIRRGLVRDLLSLKPDVFVGIDAPDFNLGVAEKLKRSGIPTVHYVSPSVWAW 134 Query: 133 RGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQPDTMVARQRLSLN 192 R R+ KI V+ +L +FP E +Y AG +VGHP+A+++PL+ D ARQ L ++ Sbjct: 135 RRERVGKIVHQVNRVLCLFPMEPQLYLDAGGRAEFVGHPMAQLMPLEDDRETARQTLGVD 194 Query: 193 GPGRVVAILPGSRMSELKQNGAGFLAAARLLKQRDAQLQFVTPMAGDRQMAAFQEQIRQG 252 V A+LPGSR+SE+ F A LL +R +F+ P A + E +++ Sbjct: 195 AGIPVFALLPGSRVSEIDYMAPVFFQTALLLLERYPAARFLLPAATEATKRRLAEVLQRP 254 Query: 253 GYEDLDISVIRGQSHSAMEAADAVLVASGTASLEVALYKKPMVISYKVNWASYQIMRHMA 312 + L ++VI QS + AADAVLV SGTA+LEVAL K+PMVISYK++ +Y ++ Sbjct: 255 EFAGLPLTVIDRQSETVCRAADAVLVTSGTATLEVALCKRPMVISYKISPLTYAYVKRKI 314 Query: 313 YQPWVGLPNILAREFLVPELLQNQATPQALADAM--WFQLEDHAHQQRLARRFADMHQSL 370 P VGLPNIL + VPELLQ++A P+ LA A+ W++ D L + F +H L Sbjct: 315 KVPHVGLPNILLGKEAVPELLQSEAKPEKLAAALADWYEHPDKVAA--LQQDFRALHLLL 372 Query: 371 LRDTSRESANAVCEVIGV 388 +DT+ +A AV E G Sbjct: 373 KKDTADLAARAVLEEAGC 390 >NMA0069 [M] COG0763 Lipid A disaccharide synthetase NmA Neisseria meningitidis Z2491 Length = 384 Score = 300 bits (768), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 164/378 (43%), Positives = 234/378 (61%), Gaps = 4/378 (1%) Query: 13 IALVAGESSGDLLGSRLLAGVRERLPEVRLHGIGGEHMMAQGFTSDWPMDKLTVRGLFEV 72 IA+ GE+SGDLLG+ L+ +R+R P+ R GIGGE M A+GF S + ++L VRG EV Sbjct: 9 IAVSVGEASGDLLGAHLIRAIRKRCPQARFVGIGGELMKAEGFESLYDQERLAVRGFVEV 68 Query: 73 IPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIPTIHFIGPQIWAW 132 + R EI I+ L LL+ +PDVFVG+D P FNLG+ E+LK++GIPT+H++ P +WAW Sbjct: 69 VRRLPEILRIRRGLVRDLLSLKPDVFVGIDAPDFNLGVAERLKRSGIPTVHYVSPSVWAW 128 Query: 133 RGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQPDTMVARQRLSLN 192 R R+ KI V+ +L +FP E +Y AG +VGHP+A+++PL+ D AR+ L ++ Sbjct: 129 RRERVGKIVHQVNRVLCLFPMEPQLYLDAGGRAEFVGHPMAQLMPLEDDRETARKTLGVD 188 Query: 193 GPGRVVAILPGSRMSELKQNGAGFLAAARLLKQRDAQLQFVTPMAGDRQMAAFQEQIRQG 252 V A+LPGSR+SE+ F A LL +R +F+ P A + E +++ Sbjct: 189 AGIPVFALLPGSRVSEIDYMAPVFFQTALLLLKRYPAARFLLPAATEATKRRLAEILQRS 248 Query: 253 GYEDLDISVIRGQSHSAMEAADAVLVASGTASLEVALYKKPMVISYKVNWASYQIMRHMA 312 + L ++V QS + AADAVLV SGTA+LEVAL K+PMVISYK++ +Y ++ Sbjct: 249 EFAGLPLTVTDRQSETVCRAADAVLVTSGTATLEVALCKRPMVISYKISPLTYAYVKRKI 308 Query: 313 YQPWVGLPNILAREFLVPELLQNQATPQALADAM--WFQLEDHAHQQRLARRFADMHQSL 370 P VGLPNIL + VPELLQ+ A P+ LA A+ W++ D L + F +H L Sbjct: 309 KVPHVGLPNILLGKEAVPELLQHDAVPEKLAAALADWYEHPDKVAA--LQQDFRVLHLLL 366 Query: 371 LRDTSRESANAVCEVIGV 388 +DT+ +A AV E G Sbjct: 367 KKDTADLAARAVLEEAGC 384 >PM1997 [M] COG0763 Lipid A disaccharide synthetase Pmu Pasteurella multocida Length = 392 Score = 288 bits (736), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 151/375 (40%), Positives = 236/375 (62%), Gaps = 5/375 (1%) Query: 12 SIALVAGESSGDLLGSRLLAGVRERLPEVRLHGIGGEHMMAQGFTSDWPMDKLTVRGLFE 71 +IA+VAGE SGD+LG+ L+ ++ + P R GI G M+A+G + M++L+V GL E Sbjct: 10 TIAIVAGEVSGDILGAGLIRSLKVQYPHARFIGIAGPRMLAEGAETLVDMEELSVMGLAE 69 Query: 72 VIPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIPTIHFIGPQIWA 131 V+ + I+ L +L ++PD+F+G+D P FN+ +E +LK+ GI TIH++ P +WA Sbjct: 70 VVKHLPRLLKIRRQLIHTMLQEKPDIFIGIDAPDFNIDVELKLKENGIKTIHYVSPSVWA 129 Query: 132 WRGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQPDTMVARQRLSL 191 WR RI KI +A +L PFE++ Y + VP ++GH +A+ I L+P+ A + L+L Sbjct: 130 WRQNRIHKIAKATHLVLAFLPFEKAFYDRFEVPCRFIGHTMADAIALKPNRQEACEYLNL 189 Query: 192 NGPGRVVAILPGSRMSELKQNGAGFLAAARLLKQRDAQLQFVTPMAGDRQMAAFQEQIRQ 251 + R VAIL GSR SE+ FL AA+LLKQ+ +QF+ P+ ++ F EQI+ Sbjct: 190 DASQRYVAILVGSRGSEVTFLAEPFLQAAKLLKQQYPDIQFLVPLINAKRREQF-EQIKA 248 Query: 252 GGYEDLDISVIRGQSHSAMEAADAVLVASGTASLEVALYKKPMVISYKVNWASYQIMRHM 311 +L++ ++ G++ AM AA+A L+ASGTA+LE L K PMV+ Y++ +Y + + + Sbjct: 249 QVAPELELILLDGKARQAMIAAEATLLASGTAALEAMLCKSPMVVGYRMKATTYFLAKRL 308 Query: 312 AYQPWVGLPNILAREFLVPELLQNQATPQALAD--AMWFQLEDHAHQQR--LARRFADMH 367 +V LPN+LA E LVPEL+Q Q T + LA+ A++ E+ A QQR L +RF D+H Sbjct: 309 VKTEYVSLPNLLANEMLVPELIQEQCTAENLAEKLALYLSQEESALQQRHTLIQRFTDLH 368 Query: 368 QSLLRDTSRESANAV 382 + + D +++A AV Sbjct: 369 KLIQCDADKQAAQAV 383