BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0413.p (448 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC1851 Non COG 204 2e-52 VC0137 Non COG 187 4e-47 BS_yuxH [T] COG3434 Predicted signal transduction protein contai... 185 2e-46 VC0515 Non COG 133 8e-31 aq_478 [T] COG3434 Predicted signal transduction protein contain... 120 5e-27 >VC1851 Non COG Length = 404 Score = 204 bits (520), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 134/378 (35%), Positives = 212/378 (56%), Gaps = 18/378 (4%) Query: 19 YLARQPILSREQHLIGYELLFRSAAFGPANVKDDV---TATAAVIAHASELGLSNVIGNL 75 Y+ARQPIL RE+ IGYELLFR GP N D+ AT+ +++ + +G+L Sbjct: 5 YVARQPILDREKSTIGYELLFRD---GPKNTFPDIDPEEATSRLLSDHFLTAHYSTLGDL 61 Query: 76 QGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAE 135 GF+N L++ P +V+EILE TPEL+ ++++ + GY ALDD + Sbjct: 62 LGFVNFPYQSLLNMVPTLFPVKSLVVEILEDCPPTPELLSAIKKMAQLGYKIALDDFIP- 120 Query: 136 SQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQK-ELLAEKVETLQQFNDCVTFGF 194 S + + LP + IIK D+ V P KL ++ R+ K E LAEKVET ++F GF Sbjct: 121 SNDWKAFLPYISIIKFDIRLV-PIPKAKLFINKLRSMKIEFLAEKVETYEEFEQAKQAGF 179 Query: 195 DYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVR-NVDNGEIVRFIKRDVALSLTLLRL 253 YFQGY+F+KP I+Q K L+ S + I+ LL + + VD EI + +D++LS LL Sbjct: 180 HYFQGYFFSKPEIIQRKALQPSFLTIVQLLKEVAKPEVDFREIETIVAKDISLSYKLLTF 239 Query: 254 VNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKM 313 VN+ K I S QAL+ LG+++L++++ ++ A+T + + L IL A +M Sbjct: 240 VNSSATVSSK-IQSFRQALVYLGQQKLRKFISLVAIASTQDSKPDYLYNLAILRARFCEM 298 Query: 314 L-ELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTGF 372 L E + T I PG F G+ S++D+L S++++++++ + E+++AL + +G Sbjct: 299 LSERVPTNIAPG------TGFLTGMFSVLDSLLDQSLDSIVKEMPIEEEVKQALTQGSGT 352 Query: 373 YGVALRLVECTEQRDQDQ 390 G L L + E D Q Sbjct: 353 LGQILALNKAYEMADWGQ 370 >VC0137 Non COG Length = 432 Score = 187 bits (475), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 135/412 (32%), Positives = 214/412 (51%), Gaps = 17/412 (4%) Query: 19 YLARQPILSREQHLIGYELLFRSA---AFGPANVKDDVTATAAVIAHASELGLSNVIGNL 75 Y+ARQPIL+ ++H +GYELLFR AF P + D ++ + LG + I Sbjct: 29 YVARQPILNAKRHTLGYELLFRDGEKNAF-PEYMDADRATYRLIVENFLSLGTNPRIARS 87 Query: 76 QGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAE 135 + FIN L+ LP +++V+EILET + T +L V+EL + GY+ ALDD V Sbjct: 88 RCFINFPHKSLIRRLPLTLPREQIVVEILETCQPTDDLFEAVQELSQRGYLLALDDFVY- 146 Query: 136 SQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQ---KELLAEKVETLQQFNDCVTF 192 S E LP V+I+KID+M + K + V + AQ + LAE+VET +F+ Sbjct: 147 SPAWERFLPYVQIVKIDIMAMGLDKACEF-VRGRLAQGSRRRFLAERVETEDEFHQARHA 205 Query: 193 GFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVR-NVDNGEIVRFIKRDVALSLTLL 251 GF +FQGY+F+KP I++ + + ++ M L + + VD + R + +D+ALS LL Sbjct: 206 GFTFFQGYFFSKPEIIKQRYVSPEHVIAMQLFREVCQPEVDYVRVERLVAQDIALSYKLL 265 Query: 252 RLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRG 311 R VNT I S QAL+ LG+ +L+ ++ + + + ++ L L+ R Sbjct: 266 RFVNTMSDRISVSISSFRQALVYLGQDKLRIFVSLAVASYISSKKPKE---LYNLSLQRA 322 Query: 312 KMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTG 371 + +L+ T + E AF +G+ S++DAL S+E ++ Q+ ++ +++ AL R G Sbjct: 323 QFCQLMATHTH--FKAHREQAFLIGMFSVLDALLDTSIEQLVEQLPLADDVKLALREREG 380 Query: 372 FYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSISN 423 G L L EC E+ D E L EL +D + A W I+ Sbjct: 381 PLGTLLDLEECFEKADWQGVEQHCL--ELGFDLEDVRQELIEAQRWSQDINR 430 >BS_yuxH [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains Bsu Bacillus subtilis Length = 409 Score = 185 bits (469), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 119/414 (28%), Positives = 217/414 (52%), Gaps = 23/414 (5%) Query: 19 YLARQPILSREQHLIGYELLFRSAAFGPANVKD-DVTATAAVIAHASELGLSNVIGNLQG 77 ++ARQPI +R++ ++ YELL+R + + KD D T VI +G+ + + Sbjct: 4 FVARQPIFNRKEQVVAYELLYRESEENVYSAKDGDQATTDLVINSFLNIGIEKLTEGKRC 63 Query: 78 FINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAESQ 137 F+N +++ S+ ++V+EILE + +TP L+ R +EL K GY+ ALDD A + Sbjct: 64 FVNFTESLMFSNLPTSFNPKQLVIEILEDIPITPALISRCKELKKMGYMLALDDFYAINP 123 Query: 138 E----IEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFG 193 + +E+L+ + I+KID ++ + + + LAEKVET +++ V G Sbjct: 124 QDEDLLEKLMSYIDILKIDFLKTTRMERRTILQTYGCRGLIFLAEKVETRKEYKQAVQDG 183 Query: 194 FDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDN-GEIVRFIKRDVALSLTLLR 252 F FQGY+F++P I+ G L LL L + N + +I+RD++LS +L+ Sbjct: 184 FQLFQGYFFSEPRIISGHDLSTHFYSYYELLNELSKEQPNIKRVTEYIERDLSLSYQILK 243 Query: 253 LVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGK 312 +N+ + I+S+ QA+++LG ++KRW+ IL F + ++ + ++ ++ R K Sbjct: 244 FLNSSHSRLSQKIESIQQAIMLLGFNEIKRWIYILSFKDLSRKGHSSKHEIIKISLIRAK 303 Query: 313 MLELI---TTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRR 369 + EL+ T+R +P + +G+ SL+D L +E +++++ + E+ +ALL Sbjct: 304 LCELLARKTSRPQPASYML------IGMFSLIDTLLHREIEEIVQELPLKDEVGQALLGH 357 Query: 370 TGFYGVALRLVECTEQRDQDQAEMQRLLDEL--QLSADDFFEAEKHAFEWGNSI 421 Y L LV+ E + D EL QL ++ +E A EW +++ Sbjct: 358 QNDYYQMLELVKLIESNNWDTC------SELGNQLDKEEAYECYLEALEWCHNL 405 >VC0515 Non COG Length = 410 Score = 133 bits (335), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 112/367 (30%), Positives = 178/367 (48%), Gaps = 19/367 (5%) Query: 16 LDFYLARQPILSREQHLIGYELLFRSAAFG--PANVKDDVTATAAVIAHASELGLSNVI- 72 +D ++A+Q I ++GYELLFR++ P V + + + + + V+ Sbjct: 1 MDSFIAKQAITDENLTIVGYELLFRNSEKNRYPEGVSESLATKKIIWQQFVDDTIDRVVE 60 Query: 73 GNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDV 132 + FIN +L+ + LP DKVV+E+LE T +L+ +R L + GY+FALDDV Sbjct: 61 SDKLCFINFPEDLLIDGYAEILPKDKVVIEVLENTIPTEKLLSVIRGLREKGYLFALDDV 120 Query: 133 VAES-QEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVT 191 + + L L +KID +D LKL K LAEKVET +Q Sbjct: 121 TRTVFENWHDYLSLFDFVKIDTRRID-DDFLKLFFSLKPICCIALAEKVETNEQLESLKK 179 Query: 192 FGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLV-RNVDNGEIVRFIKRDVALSLTL 250 GF FQG+Y +P +L+ E + LL ++ R+ + + + R+ L++ L Sbjct: 180 NGFLLFQGFYLDRPKVLRCATTEYANTESFELLIEVIKRDFNPSRLELILIRNPKLTVGL 239 Query: 251 LRLVNT---PVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILA 307 L+ VNT P+ K I S+ A++ LG QL R LL ++T ++ + +L Sbjct: 240 LKYVNTIGKPL----KPISSIQHAIVYLGLEQL-RMFVFLLCSSTIHDKLDLDKYVYVL- 293 Query: 308 ATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALL 367 TR K EL+ I K+S MAF G++SL +L + +S ++R+A+L Sbjct: 294 -TRAKFCELMMGEI---DHKLSSMAFISGMLSLSHLFLPNDNSELLSSLPISNDMRDAVL 349 Query: 368 RRTGFYG 374 R G G Sbjct: 350 CRAGILG 356 >aq_478 [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains Aae Aquifex aeolicus Length = 411 Score = 120 bits (302), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 103/363 (28%), Positives = 180/363 (49%), Gaps = 27/363 (7%) Query: 16 LDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHAS---ELGLSNVI 72 + F +ARQPI R + YE R +DV + AV E G+ + Sbjct: 1 MSFVVARQPIFDRNGEVFAYEFFLRREG-DEEKYPEDVPFSRAVYIITDILVESGIEKLA 59 Query: 73 GNLQGFINVDAAVLMSDFIYFLPNDKVVLEIL-------ETVRVTPELVVRVRELVKAGY 125 + INV +++ + LP DKV+ ++ ET++ +++ ++++ G Sbjct: 60 NGKKAVINVSLEAILNKSLELLPPDKVIFDLNPPEVPLGETLK--QKVLQKLKDYKGKGV 117 Query: 126 VFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQ 185 F L++ + S E +EL+ L I++ V P K+ KR K++L +E ++ Sbjct: 118 SFILNERLY-SSEHKELINLSDIVEFYFKSVTPDKIRSA----KRYGKKVLVSMIEKEEE 172 Query: 186 FNDCVTFGFDYFQGYYFAKPMILQGKKLEAS-KMVIMHLLTLLVRNVDNGEIVRFIKRDV 244 + + +G DYFQG+YFAKP I++ KL K+ ++ LL + EI I+ DV Sbjct: 173 YKKALEYGADYFQGFYFAKPEIVKRTKLAPFLKVTLLRLLNAISIARSLKEIADIIETDV 232 Query: 245 ALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSP-L 303 L++ L+ VN+ + +K I+SL A+ +G +K+++ IL+ N E +P L Sbjct: 233 GLAVKFLQFVNSAYFARRKKIESLEHAVSFVGMENIKKFV-ILVSMN---EFLKVENPEL 288 Query: 304 MILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIR 363 + TR + E +T R P ++SE AF VG+ SL+D + + + T LR++ V E+ Sbjct: 289 WRKSLTRAFIAEELTNRYSP---EVSEKAFLVGLFSLLDKILEVDIPTFLRELNVDEEVV 345 Query: 364 EAL 366 +A Sbjct: 346 KAF 348