BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0370.p (351 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1319 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Rso... 599 e-171 YPO2420_2 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Y... 391 e-108 STM2299_2 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases S... 385 e-107 yfbG_2 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Eco ... 378 e-105 ECs3143_2 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases E... 378 e-104 >RSc1319 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Rso Ralstonia solanacearum Length = 351 Score = 599 bits (1544), Expect = e-171, Method: Compositional matrix adjust. Identities = 288/356 (80%), Positives = 312/356 (87%), Gaps = 10/356 (2%) Query: 1 MKKVLILGVNGFIGHHLSKRILETTD-----WHVYGMDMMTDRITDILENEAYKSRMHFF 55 MKKVLILGVNGFIGHHLSKRILE+TD W VYGMDM T+R+ D++ + RMHFF Sbjct: 1 MKKVLILGVNGFIGHHLSKRILESTDPEISQWEVYGMDMQTERLGDLVNH----PRMHFF 56 Query: 56 EGDITINQEWVEYHVKKCDVILPLVAIATPSTYVNAPLRVFELDFEANLPIVRSAAKYKK 115 EGDITIN+EWVEYHV+KCDVILPLVAIATPSTYV APLRVFELDFEANLPIVRSAAKY K Sbjct: 57 EGDITINKEWVEYHVRKCDVILPLVAIATPSTYVKAPLRVFELDFEANLPIVRSAAKYGK 116 Query: 116 HLVFPSTSEVYGMCHDEEFDPEESELICGPINKPRWIYSCAKQLMDRVIWGYGMEAGLNF 175 HLVFPSTSEVYGMC D+EFDPE S L+ GPINKPRWIY+C+KQLMDRVIWGYGME GLNF Sbjct: 117 HLVFPSTSEVYGMCGDDEFDPEASPLVYGPINKPRWIYACSKQLMDRVIWGYGME-GLNF 175 Query: 176 TLFRPFNWIGAGLDSIHTPKEGSSRVVTQFFGHIVRGENISLVDGGLQKRAFTYIDDGID 235 TLFRPFNWIG GLDSIHTPKEGSSRVVTQF GHIVRGENI LVDGG QKRAFTY+DDGID Sbjct: 176 TLFRPFNWIGPGLDSIHTPKEGSSRVVTQFLGHIVRGENIQLVDGGQQKRAFTYVDDGID 235 Query: 236 ALMKIIANEGGVASGKIYNIGNPVNNYSIKELADMMLKLAAEYPEYAETAKQVKLVETTS 295 AL++IIAN+ GVASGKIYNIGNP NNYS++ELA+MMLK A EY E A++VKLVETTS Sbjct: 236 ALVRIIANKDGVASGKIYNIGNPSNNYSVRELAEMMLKKAGTIAEYKENAQKVKLVETTS 295 Query: 296 AAYYGKGYQDVQNRVPKITNTCEELNWAPTTTMADTLRNIFDAYRSQVAEARALMD 351 AYYGKGYQDVQNRVPKI NT EEL W PTTTM DTL NIF+AYR AEAR+L+D Sbjct: 296 GAYYGKGYQDVQNRVPKIANTMEELGWKPTTTMEDTLANIFEAYREHAAEARSLVD 351 >YPO2420_2 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Ype Yersinia pestis Length = 363 Score = 391 bits (1004), Expect = e-108, Method: Compositional matrix adjust. Identities = 195/353 (55%), Positives = 241/353 (68%), Gaps = 17/353 (4%) Query: 3 KVLILGVNGFIGHHLSKRILETTDWHVYGMDMMTDRITDILENEAYKSRMHFFEGDITIN 62 +VLILGVNGFIG+HL++R+L+ + VYG+D+ +D I+ L N A+ HF EGDI+I+ Sbjct: 13 RVLILGVNGFIGNHLTERLLQDDRYEVYGLDIGSDAISRFLGNPAF----HFVEGDISIH 68 Query: 63 QEWVEYHVKKCDVILPLVAIATPSTYVNAPLRVFELDFEANLPIVRSAAKYKKHLVFPST 122 EW+EYH+KKCDVILPLVAIATP Y PLRVFELDFE NL IVR KY K +VFPST Sbjct: 69 SEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRDCVKYNKRIVFPST 128 Query: 123 SEVYGMCHDEEFDPEESELICGPINKPRWIYSCAKQLMDRVIWGYGMEAGLNFTLFRPFN 182 SEVYGMC D+EFD + S LI GPINK RWIYS +KQL+DRVIW YG++ GL FTLFRPFN Sbjct: 129 SEVYGMCDDKEFDEDTSRLIVGPINKQRWIYSVSKQLLDRVIWAYGVKEGLKFTLFRPFN 188 Query: 183 WIGAGLDSIHTPKEGSSRVVTQFFGHIVRGENISLVDGGLQKRAFTYIDDGIDALMKIIA 242 W+G LD++ + GSSR +TQ ++V G I LVDGG QKR FT I DGI+AL +II Sbjct: 189 WMGPRLDNLDAARIGSSRAITQLILNLVEGSPIKLVDGGAQKRCFTDIHDGIEALFRIIE 248 Query: 243 NEGGVASGKIYNIGNPVNNYSIKELADMML------KLAAEYPEYAETAKQVKLVETTSA 296 N G G+I NIGNP N SI+ELA+M+L +L +P +A + S+ Sbjct: 249 NRDGCCDGRIINIGNPTNEASIRELAEMLLTSFENHELRDHFPPFA------GFKDIESS 302 Query: 297 AYYGKGYQDVQNRVPKITNTCEELNWAPTTTMADTLRNIFDAY-RSQVAEARA 348 AYYGKGYQDV+ R P I N L+W P M T+ D + R+ V E A Sbjct: 303 AYYGKGYQDVEYRTPSIKNARRILHWQPEIAMQQTVTETLDFFLRAAVIEKTA 355 >STM2299_2 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Sty Salmonella typhimurium LT2 Length = 353 Score = 385 bits (988), Expect = e-107, Method: Compositional matrix adjust. Identities = 187/341 (54%), Positives = 232/341 (68%), Gaps = 4/341 (1%) Query: 3 KVLILGVNGFIGHHLSKRILETTDWHVYGMDMMTDRITDILENEAYKSRMHFFEGDITIN 62 +VLILGVNGFIG+HL++R+L ++ VYGMD+ ++ I+ L R HF EGDI+I+ Sbjct: 10 RVLILGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFL----LHPRFHFVEGDISIH 65 Query: 63 QEWVEYHVKKCDVILPLVAIATPSTYVNAPLRVFELDFEANLPIVRSAAKYKKHLVFPST 122 EW+EYHVKKCDV+LPLVAIATP Y PLRVFELDFE NL I+R KY+K +VFPST Sbjct: 66 SEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRVVFPST 125 Query: 123 SEVYGMCHDEEFDPEESELICGPINKPRWIYSCAKQLMDRVIWGYGMEAGLNFTLFRPFN 182 SEVYGMC D FD ++S LI GP+NKPRWIYS +KQL+DRVIW YG + GL FTLFRPFN Sbjct: 126 SEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLRFTLFRPFN 185 Query: 183 WIGAGLDSIHTPKEGSSRVVTQFFGHIVRGENISLVDGGLQKRAFTYIDDGIDALMKIIA 242 W+G LDS++ + GSSR +TQ ++V G I L+DGG QKR FT I DGI+AL +II Sbjct: 186 WMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIV 245 Query: 243 NEGGVASGKIYNIGNPVNNYSIKELADMMLKLAAEYPEYAETAKQVKLVETTSAAYYGKG 302 N+G GKI NIGNP N SI+ELA ++L ++P S +YYGKG Sbjct: 246 NDGDRCDGKIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKG 305 Query: 303 YQDVQNRVPKITNTCEELNWAPTTTMADTLRNIFDAYRSQV 343 YQDV +R P I N L W P+ M DT+ D + V Sbjct: 306 YQDVAHRKPSIDNARRCLGWEPSIAMRDTVEETLDFFLRSV 346 >yfbG_2 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Eco Escherichia coli K12 Length = 355 Score = 378 bits (971), Expect = e-105, Method: Compositional matrix adjust. Identities = 182/341 (53%), Positives = 233/341 (68%), Gaps = 4/341 (1%) Query: 3 KVLILGVNGFIGHHLSKRILETTDWHVYGMDMMTDRITDILENEAYKSRMHFFEGDITIN 62 +VLILGVNGFIG+HL++R+L + VYG+D+ +D I+ L + + HF EGDI+I+ Sbjct: 12 RVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHF----HFVEGDISIH 67 Query: 63 QEWVEYHVKKCDVILPLVAIATPSTYVNAPLRVFELDFEANLPIVRSAAKYKKHLVFPST 122 EW+EYHVKKCDV+LPLVAIATP Y PLRVFELDFE NL I+R KY+K ++FPST Sbjct: 68 SEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPST 127 Query: 123 SEVYGMCHDEEFDPEESELICGPINKPRWIYSCAKQLMDRVIWGYGMEAGLNFTLFRPFN 182 SEVYGMC D+ FD + S LI GP+NKPRWIYS +KQL+DRVIW YG + GL FTLFRPFN Sbjct: 128 SEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFN 187 Query: 183 WIGAGLDSIHTPKEGSSRVVTQFFGHIVRGENISLVDGGLQKRAFTYIDDGIDALMKIIA 242 W+G LD+++ + GSSR +TQ ++V G I L+DGG QKR FT I DGI+AL +II Sbjct: 188 WMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIE 247 Query: 243 NEGGVASGKIYNIGNPVNNYSIKELADMMLKLAAEYPEYAETAKQVKLVETTSAAYYGKG 302 N G G+I NIGNP N SI+EL +M+L ++P S++YYGKG Sbjct: 248 NAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKG 307 Query: 303 YQDVQNRVPKITNTCEELNWAPTTTMADTLRNIFDAYRSQV 343 YQDV++R P I N L+W P M +T+ D + V Sbjct: 308 YQDVEHRKPSIRNAHRCLDWEPKIDMQETIDETLDFFLRTV 348 >ECs3143_2 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Ecs Escherichia coli O157:H7 Length = 355 Score = 378 bits (971), Expect = e-104, Method: Compositional matrix adjust. Identities = 182/341 (53%), Positives = 233/341 (68%), Gaps = 4/341 (1%) Query: 3 KVLILGVNGFIGHHLSKRILETTDWHVYGMDMMTDRITDILENEAYKSRMHFFEGDITIN 62 +VLILGVNGFIG+HL++R+L + VYG+D+ +D I+ L + + HF EGDI+I+ Sbjct: 12 RVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHF----HFVEGDISIH 67 Query: 63 QEWVEYHVKKCDVILPLVAIATPSTYVNAPLRVFELDFEANLPIVRSAAKYKKHLVFPST 122 EW+EYHVKKCDV+LPLVAIATP Y PLRVFELDFE NL I+R KY+K ++FPST Sbjct: 68 SEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPST 127 Query: 123 SEVYGMCHDEEFDPEESELICGPINKPRWIYSCAKQLMDRVIWGYGMEAGLNFTLFRPFN 182 SEVYGMC D+ FD + S LI GP+NKPRWIYS +KQL+DRVIW YG + GL FTLFRPFN Sbjct: 128 SEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFN 187 Query: 183 WIGAGLDSIHTPKEGSSRVVTQFFGHIVRGENISLVDGGLQKRAFTYIDDGIDALMKIIA 242 W+G LD+++ + GSSR +TQ ++V G I L+DGG QKR FT I DGI+AL +II Sbjct: 188 WMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIE 247 Query: 243 NEGGVASGKIYNIGNPVNNYSIKELADMMLKLAAEYPEYAETAKQVKLVETTSAAYYGKG 302 N G G+I NIGNP N SI+EL +M+L ++P S++YYGKG Sbjct: 248 NAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKG 307 Query: 303 YQDVQNRVPKITNTCEELNWAPTTTMADTLRNIFDAYRSQV 343 YQDV++R P I N L+W P M +T+ D + V Sbjct: 308 YQDVEHRKPSIRNAHHCLDWEPKIDMQETIDETLDFFLRTV 348