BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0277.p (471 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO3099_1 [M] COG0836 Mannose-1-phosphate guanylyltransferase Yp... 402 e-111 ECs2854_1 [M] COG0836 Mannose-1-phosphate guanylyltransferase Ec... 350 3e-96 ZcpsB_1 [M] COG0836 Mannose-1-phosphate guanylyltransferase EcZ ... 350 3e-96 cpsB_1 [M] COG0836 Mannose-1-phosphate guanylyltransferase Eco E... 347 3e-95 STM2084_1 [M] COG0836 Mannose-1-phosphate guanylyltransferase St... 347 3e-95 >YPO3099_1 [M] COG0836 Mannose-1-phosphate guanylyltransferase Ype Yersinia pestis Length = 354 Score = 402 bits (1032), Expect = e-111, Method: Compositional matrix adjust. Identities = 203/355 (57%), Positives = 254/355 (71%), Gaps = 2/355 (0%) Query: 1 MKIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGN 60 + + PVI++GGAG+RLWPLSRA YPKQ L L S+ TMLQET+ R+ P LAPLV+C Sbjct: 2 LMLLPVIMAGGAGSRLWPLSRALYPKQFLALTSDLTMLQETLLRLDGLPH-LAPLVICNE 60 Query: 61 EHRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITN 120 EHRF+IAEQLR+ ++ IVLEP G+NTAPA+A AAL+ D ++LVL ADHVI + Sbjct: 61 EHRFIIAEQLRQKNLVHSGIVLEPVGRNTAPAIALAALRATMSGDDPLLLVLAADHVIQD 120 Query: 121 REAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDTGNFAVERFVEKPDL 180 + AF AV+ A E G LVTFGI P PETGYGYI +G D G + V FVEKPDL Sbjct: 121 KLAFIRAVQRAEPLAEAGKLVTFGIVPKSPETGYGYIRQGKQVVD-GAYQVAAFVEKPDL 179 Query: 181 ERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGEA 240 A+ ++A G YYWNSGMF+ +A YL+EL+LHRP I AA K A+A +TDLDF RL E Sbjct: 180 ITAERYLASGDYYWNSGMFVFKASRYLQELDLHRPDILAACKQAIAGQHTDLDFIRLNEE 239 Query: 241 AFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLDG 300 AF + P ESIDYAVME T AVVVP D W+DVG WSAL E+ D GNV RGDV ++ Sbjct: 240 AFSSCPDESIDYAVMEKTSDAVVVPLDAQWNDVGCWSALWEINTKDDHGNVIRGDVLIED 299 Query: 301 VSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSE 355 +NS V +++R++A +G+ DL++VET DA+LVAHKDK Q+VKG+V QLK + R E Sbjct: 300 TNNSYVYSQNRLIATVGINDLVIVETKDAILVAHKDKVQNVKGIVGQLKLESRCE 354 >ECs2854_1 [M] COG0836 Mannose-1-phosphate guanylyltransferase Ecs Escherichia coli O157:H7 Length = 341 Score = 350 bits (899), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 189/337 (56%), Positives = 233/337 (69%), Gaps = 6/337 (1%) Query: 2 KIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGNE 61 K+YPV+++GG+G+RLWPLSR YPKQ L L + TMLQ T+ R+ E +P+V+C + Sbjct: 5 KLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNG-VECESPVVICNEQ 63 Query: 62 HRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDP--DAVMLVLPADHVIT 119 HRF++AEQLR+++ I+LEP G+NTAPA+A AAL R P D +MLVL ADHVI Sbjct: 64 HRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAAKRHSPENDPLMLVLAADHVIA 123 Query: 120 NREAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRG---AAHGDTGNFAVERFVE 176 + +AF AVR AM E G LVTFGI P PETGYGYI RG A DT F V +FVE Sbjct: 124 DEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGYIRRGEVSAGEQDTVAFEVAQFVE 183 Query: 177 KPDLERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCR 236 KP+LE AQ +VA G YYWNSGMFL RA YLEEL+ +RP I A + A++ DLDF R Sbjct: 184 KPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELKKYRPDILDACEKAMSAVDPDLDFIR 243 Query: 237 LGEAAFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDV 296 + E AF A P ES+DYAVME T AVVVP D GWSDVGSWS+L E+ A+GNV GDV Sbjct: 244 VDEDAFLACPEESVDYAVMERTADAVVVPMDAGWSDVGSWSSLWEISAHTAEGNVCHGDV 303 Query: 297 YLDGVSNSLVRAESRMVAVLGLQDLIVVETDDAVLVA 333 NS V AES +V +G++DL+VV+T DAVL+A Sbjct: 304 INHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLIA 340 >ZcpsB_1 [M] COG0836 Mannose-1-phosphate guanylyltransferase EcZ Escherichia coli O157:H7 EDL933 Length = 341 Score = 350 bits (899), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 189/337 (56%), Positives = 233/337 (69%), Gaps = 6/337 (1%) Query: 2 KIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGNE 61 K+YPV+++GG+G+RLWPLSR YPKQ L L + TMLQ T+ R+ E +P+V+C + Sbjct: 5 KLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNG-VECESPVVICNEQ 63 Query: 62 HRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDP--DAVMLVLPADHVIT 119 HRF++AEQLR+++ I+LEP G+NTAPA+A AAL R P D +MLVL ADHVI Sbjct: 64 HRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAAKRHSPENDPLMLVLAADHVIA 123 Query: 120 NREAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRG---AAHGDTGNFAVERFVE 176 + +AF AVR AM E G LVTFGI P PETGYGYI RG A DT F V +FVE Sbjct: 124 DEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGYIRRGEVSAGEQDTVAFEVAQFVE 183 Query: 177 KPDLERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCR 236 KP+LE AQ +VA G YYWNSGMFL RA YLEEL+ +RP I A + A++ DLDF R Sbjct: 184 KPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELKKYRPDILDACEKAMSAVDPDLDFIR 243 Query: 237 LGEAAFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDV 296 + E AF A P ES+DYAVME T AVVVP D GWSDVGSWS+L E+ A+GNV GDV Sbjct: 244 VDEDAFLACPEESVDYAVMERTADAVVVPMDAGWSDVGSWSSLWEISAHTAEGNVCHGDV 303 Query: 297 YLDGVSNSLVRAESRMVAVLGLQDLIVVETDDAVLVA 333 NS V AES +V +G++DL+VV+T DAVL+A Sbjct: 304 INHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLIA 340 >cpsB_1 [M] COG0836 Mannose-1-phosphate guanylyltransferase Eco Escherichia coli K12 Length = 341 Score = 347 bits (891), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 187/337 (55%), Positives = 232/337 (68%), Gaps = 6/337 (1%) Query: 2 KIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGNE 61 K+YPV+++GG+G+RLWPLSR YPKQ L L + TMLQ T+ R+ E +P+V+C + Sbjct: 5 KLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNG-VECESPVVICNEQ 63 Query: 62 HRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDP--DAVMLVLPADHVIT 119 HRF++AEQLR+++ I+LEP G+NTAPA+A AAL R P D +MLVL ADHVI Sbjct: 64 HRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAAKRHSPESDPLMLVLAADHVIA 123 Query: 120 NREAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRG---AAHGDTGNFAVERFVE 176 + +AF AVR AM E G LVTFGI P PETGYGYI RG A D F V +FVE Sbjct: 124 DEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGYIRRGEVSAGEQDMVAFEVAQFVE 183 Query: 177 KPDLERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCR 236 KP+LE AQ +VA G YYWNSGMFL RA YLEEL+ +RP I A + A++ DL+F R Sbjct: 184 KPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELKKYRPDILDACEKAMSAVDPDLNFIR 243 Query: 237 LGEAAFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDV 296 + E AF A P ES+DYAVME T AVVVP D GWSDVGSWS+L E+ A+GNV GDV Sbjct: 244 VDEEAFLACPEESVDYAVMERTADAVVVPMDAGWSDVGSWSSLWEISAHTAEGNVCHGDV 303 Query: 297 YLDGVSNSLVRAESRMVAVLGLQDLIVVETDDAVLVA 333 NS V AES +V +G++DL+VV+T DAVL+A Sbjct: 304 INHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLIA 340 >STM2084_1 [M] COG0836 Mannose-1-phosphate guanylyltransferase Sty Salmonella typhimurium LT2 Length = 355 Score = 347 bits (890), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 170/357 (47%), Positives = 237/357 (66%), Gaps = 4/357 (1%) Query: 1 MKIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGN 60 M PVI++GG G+RLWPLSR +PKQ L + + +MLQ T+ R+ + P+V+C + Sbjct: 1 MSFLPVIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKRLASLSTE-EPVVICND 59 Query: 61 EHRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQ--DPDAVMLVLPADHVI 118 HRF++AEQLRE+D + I+LEP G+NTAPA+A AA ++ + D ++LVL ADHVI Sbjct: 60 RHRFLVAEQLREIDKLANNIILEPVGRNTAPAIALAAFCALQNADNADPLLLVLAADHVI 119 Query: 119 TNREAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDTGNFAVERFVEKP 178 + AF +AVR A G LVTFGI P+ ETGYGYI RG G+ +AV FVEKP Sbjct: 120 QDEIAFTKAVRHAEEYAANGKLVTFGIVPTHAETGYGYIRRGELIGNDA-YAVAEFVEKP 178 Query: 179 DLERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLG 238 D++ A + G+YYWNSGMFL RA YL EL+ P I A + AV DLDF R+ Sbjct: 179 DIDTAGDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIYKACEKAVGHINPDLDFIRID 238 Query: 239 EAAFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYL 298 + F + P++SIDYAVME+T+ AVV+P GWSDVGSWS+L ++ D Q NV +GD++ Sbjct: 239 KEEFMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSWSSLWDISNKDHQRNVLKGDIFA 298 Query: 299 DGVSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSE 355 +++ + +E ++ +G+ +L++V+T DA+LVA+KD QDVK +VD LK R+E Sbjct: 299 HACNDNYIYSEDMFISAIGVSNLVIVQTTDALLVANKDTVQDVKKIVDYLKRNDRNE 355