BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0239.p (314 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2830 [O] COG0501 Zn-dependent protease with chaperone function... 302 5e-82 NMA1031 [O] COG0501 Zn-dependent protease with chaperone functio... 290 3e-78 NMB0822 [O] COG0501 Zn-dependent protease with chaperone functio... 288 9e-78 HI0720 [O] COG0501 Zn-dependent protease with chaperone function... 278 2e-74 XF2625 [O] COG0501 Zn-dependent protease with chaperone function... 277 2e-74 >PA2830 [O] COG0501 Zn-dependent protease with chaperone function Pae Pseudomonas aeruginosa Length = 291 Score = 302 bits (774), Expect = 5e-82, Method: Compositional matrix adjust. Identities = 164/295 (55%), Positives = 207/295 (70%), Gaps = 12/295 (4%) Query: 23 MKRVILFLVTNLAVMLVLSVTASLLGVNRYLTANGLNFGMLLVFCGLMGFGGSFISLFMS 82 M R++LFL TNLAV+++ S+T LLGV+R+ G N+G LLVFC + GF GS +SLF+S Sbjct: 1 MMRILLFLATNLAVLVIASITLKLLGVDRF---TGQNYGSLLVFCAVFGFAGSLVSLFIS 57 Query: 83 KTIAKWSTGARVIEQPQNSTELWLLQTVQNLAARAQLPMPEVAVYDG-PPNAFATGASKS 141 K +AK STG VI QP+ E WLLQTV+ L+ A + MPEV ++ NAFATG +K+ Sbjct: 58 KWMAKMSTGTEVISQPRTRHEQWLLQTVEELSREAGIKMPEVGIFPAYEANAFATGWNKN 117 Query: 142 NSLVAVSTGLLQGMTKDEVEAVLAHEVAHIANGDMVTLTLIQGVVNTFVMFFARIVGYFV 201 ++LVAVS GLL+ + DEV+AVLAHE+ H+ANGDMVTL LIQGVVNTFVMFFARI G FV Sbjct: 118 DALVAVSQGLLERFSPDEVKAVLAHEIGHVANGDMVTLALIQGVVNTFVMFFARIFGNFV 177 Query: 202 DSFLRRNNEENSGPGIGYMVTVFVCEIIFGILASIIVMYFSRQREYRADAGAASLMGSNA 261 D + +N + GPGIGY V E++ GILASIIVM+FSR+RE+RADA A L G+ A Sbjct: 178 DKAILKNED---GPGIGYFVATIFAELVLGILASIIVMWFSRRREFRADAAGAHLAGTGA 234 Query: 262 PMINALRRLGGMQS--DGLPQNLQAAGISG--RESWMGLFSSHPSLESRIAALQS 312 MI AL+RL Q +P L A GI+G + GL SHP LE RI AL++ Sbjct: 235 -MIAALQRLRSEQGVPVQMPDTLNAFGINGGLKHGLAGLLMSHPPLEDRIEALRA 288 >NMA1031 [O] COG0501 Zn-dependent protease with chaperone function NmA Neisseria meningitidis Z2491 Length = 279 Score = 290 bits (742), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 162/292 (55%), Positives = 215/292 (73%), Gaps = 16/292 (5%) Query: 23 MKRVILFLVTNLAVMLVLSVTASLLGVNRYLTANGLNFGMLLVFCGLMGFGGSFISLFMS 82 MKR+ LFL TN+AV++V+++ ++LG+N + G G LL + ++GF GS ISL MS Sbjct: 1 MKRIFLFLATNIAVLVVINIVLAVLGIN---SQGGT--GSLLAYSAVVGFTGSIISLLMS 55 Query: 83 KTIAKWSTGARVIEQPQNSTELWLLQTVQNLAARAQLPMPEVAVYDGP-PNAFATGASKS 141 K IAK S GA VI+ P+ E WLL TV+ A + L PEVA+Y P PNAFATGAS++ Sbjct: 56 KFIAKQSVGAEVIDTPRTEEEAWLLNTVEAQARQWNLKTPEVAIYHSPEPNAFATGASRN 115 Query: 142 NSLVAVSTGLLQGMTKDEVEAVLAHEVAHIANGDMVTLTLIQGVVNTFVMFFARIVGYFV 201 +SL+AVSTGLL MT+DEVEAVLAHE+AH+ NGDMVTLTLIQGVVNTFV+F +RI+ Sbjct: 116 SSLIAVSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVVNTFVVFLSRIIA--- 172 Query: 202 DSFLRRNNEENSGPGIGYMVTVFVCEIIFGILASIIVMYFSRQREYRADAGAASLMGSNA 261 + + RNN+ + G ++V++ V +I+FG LAS+IVM+FSRQREYRADAGAA L+G A Sbjct: 173 -NLIARNNDGSQSQGTYFLVSM-VFQILFGFLASLIVMWFSRQREYRADAGAAKLVG--A 228 Query: 262 P-MINALRRLGGMQSDGLPQNLQAAGISGRESWMGLFSSHPSLESRIAALQS 312 P MI+AL+RL G D LP+ + A GI+G ++ L S+HPSL++RIA L+S Sbjct: 229 PKMISALQRLKGNPVD-LPEEMNAMGIAG-DTRDSLLSTHPSLDNRIARLKS 278 >NMB0822 [O] COG0501 Zn-dependent protease with chaperone function Nme Neisseria meningitidis MC58 Length = 347 Score = 288 bits (738), Expect = 9e-78, Method: Compositional matrix adjust. Identities = 162/298 (54%), Positives = 216/298 (72%), Gaps = 18/298 (6%) Query: 18 HSGKIMKRVILFLVTNLAVMLVLSVTASLLGVNRYLTANGLNFGMLLVFCGLMGFGGSFI 77 G +KR+ LFL TN+AV++V+++ ++LG+N + G G LL + ++GF GS I Sbjct: 64 QKGTSVKRIFLFLATNIAVLVVINIVLAVLGIN---SRGGT--GSLLAYSAVVGFTGSII 118 Query: 78 SLFMSKTIAKWSTGARVIEQPQNSTELWLLQTVQNLAARAQLPMPEVAVYDGP-PNAFAT 136 SL MSK IAK S GA VI+ P+ E WLL TV+ A + L PEVA+Y P PNAFAT Sbjct: 119 SLLMSKFIAKQSVGAEVIDTPRTEEEAWLLNTVEAQARQWNLKTPEVAIYHSPEPNAFAT 178 Query: 137 GASKSNSLVAVSTGLLQGMTKDEVEAVLAHEVAHIANGDMVTLTLIQGVVNTFVMFFARI 196 GAS+++SL+AVSTGLL MT+DEVEAVLAHE+AH+ NGDMVTLTLIQGVVNTFV+F +RI Sbjct: 179 GASRNSSLIAVSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVVNTFVVFLSRI 238 Query: 197 VGYFVDSFLRRNNEENSGPGIGYMVTVFVCEIIFGILASIIVMYFSRQREYRADAGAASL 256 + + + RNN+ + G ++V++ V +I+FG LAS+IVM+FSRQREYRADAGAA L Sbjct: 239 IA----NLIARNNDGSQSQGTYFLVSM-VFQILFGFLASLIVMWFSRQREYRADAGAAKL 293 Query: 257 MGSNAPMINALRRLGGMQSDGLPQNLQAAGISG--RESWMGLFSSHPSLESRIAALQS 312 +G+ MI+AL+RL G D LP+ + A GI+G R+S L S+HPSL++RIA L+S Sbjct: 294 VGA-PKMISALQRLKGNPVD-LPEEMNAMGIAGDTRDS---LLSTHPSLDNRIARLKS 346 >HI0720 [O] COG0501 Zn-dependent protease with chaperone function Hin Haemophilus influenzae Length = 283 Score = 278 bits (710), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 157/295 (53%), Positives = 204/295 (69%), Gaps = 18/295 (6%) Query: 23 MKRVILFLVTNLAVMLVLSVTASLLGVNRYLTANGLNFGMLLVFCGLMGFGGSFISLFMS 82 M R++LFL TN+AVMLVL + S+ G+ G + G +L+ L GF GS ISLF+S Sbjct: 1 MMRILLFLATNMAVMLVLGIILSVTGIA------GNSTGGILIMALLFGFAGSLISLFLS 54 Query: 83 KTIAKWSTGARVIEQPQNSTELWLLQTVQNLAARAQLPMPEVAVYDGPP-NAFATGASKS 141 KT+A S VI QP+N TE WL+ TV A +A +PMP+VA+Y P NAFATGA+KS Sbjct: 55 KTMALRSVDGEVITQPRNQTERWLIDTVSRQAQKAGIPMPDVAIYHSPDVNAFATGATKS 114 Query: 142 NSLVAVSTGLLQGMTKDEVEAVLAHEVAHIANGDMVTLTLIQGVVNTFVMFFARIVGYFV 201 NSLVAVSTGLL MT+ E EAVLAHE++HI+NGDMVT+ L+QGV+NTFV+F +R++ V Sbjct: 115 NSLVAVSTGLLNNMTEAEAEAVLAHEISHISNGDMVTMALLQGVLNTFVIFLSRVIATAV 174 Query: 202 DSFLRRNNEENSGPGIGYMVTVFVCEIIFGILASIIVMYFSRQREYRADAGAASLMGSNA 261 S N EE GI ++V++ V E++FG+LASII M+FSR RE+RADAG+ASL+G Sbjct: 175 ASSRNNNGEETRSSGIYFLVSM-VLEMLFGVLASIIAMWFSRYREFRADAGSASLVGKE- 232 Query: 262 PMINALRRLGGMQSDGLPQNLQ----AAGISGRESWMGLFSSHPSLESRIAALQS 312 MI AL+RL + PQNL+ A I+G+ S LF SHP LE RI AL++ Sbjct: 233 KMIMALQRLQQLHE---PQNLEGSLNAFMINGKRS--ELFMSHPPLEKRIEALRN 282 >XF2625 [O] COG0501 Zn-dependent protease with chaperone function Xfa Xylella fastidiosa 9a5c Length = 289 Score = 277 bits (709), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 156/297 (52%), Positives = 199/297 (67%), Gaps = 13/297 (4%) Query: 22 IMKRVILFLVTNLAVMLVLSVTASLLGVNRYLTANGLNFGMLLVFCGLMGFGGSFISLFM 81 ++ R++LF +TNLAV+++ S+ SLLGVN + LLV + GF GSFISL M Sbjct: 1 MLTRIVLFAITNLAVLILASIVMSLLGVNPTQMSG------LLVMALIFGFAGSFISLLM 54 Query: 82 SKTIAKWSTGARVIEQPQNSTELWLLQTVQNLAARAQLPMPEVAVYDGPP-NAFATGASK 140 SK IAK +TGA VI+QP+N +E WLL TV A + PE+A+Y+G NAFATGA + Sbjct: 55 SKAIAKRTTGAYVIDQPRNLSERWLLDTVSRQAEIVGIGRPEIAIYEGVEINAFATGADR 114 Query: 141 SNSLVAVSTGLLQGMTKDEVEAVLAHEVAHIANGDMVTLTLIQGVVNTFVMFFARIVGYF 200 +N+LVAVSTGLLQ M++DEVEAVL HE+AH+ANGDMVT+ L+QGV+NTFV+ AR+VG F Sbjct: 115 NNALVAVSTGLLQNMSQDEVEAVLGHEIAHVANGDMVTMALLQGVLNTFVIVLARVVGGF 174 Query: 201 VDSFLRRNNEENSGPGIGYMVTVFVCEIIFGILASIIVMYFSRQREYRADAGAASLMGSN 260 +DS L N G+ Y V V E++FG+ A++I M+FSR+RE+RAD G A L G N Sbjct: 175 IDSLLSGN--RGGARGVAYYAIVLVLELLFGLFATMITMWFSRRREFRADEGGAYLAGRN 232 Query: 261 APMINALRRLG-GMQSDGLPQNLQAAGISG--RESWMGLFSSHPSLESRIAALQSRR 314 MI AL RLG LP +QA GI G E LF SHP L RIAAL+ R Sbjct: 233 -KMIAALERLGINHGQSTLPTQVQAFGIYGGIGEGLRKLFLSHPPLSERIAALRVAR 288