BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0005.0227.p         (395 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PAB0724 [GEPR] COG0477 Permeases of the major facilitator superf...    71   4e-12
TM1336 [GEPR] COG0477 Permeases of the major facilitator superfa...    61   4e-09
mlr4214 [GEPR] COG0477 Permeases of the major facilitator superf...    60   9e-09

>PAB0724 [GEPR] COG0477 Permeases of the major facilitator superfamily Pab
           Pyrococcus abyssi
          Length = 418

 Score = 71.2 bits (173), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 87/352 (24%), Positives = 165/352 (46%), Gaps = 15/352 (4%)

Query: 8   VLLQMLMFELTQSAFQVMLLVLAELAPMLLLGPWAGAVTDRSGLRRVLGGSCVARLALLL 67
           V L + + ++T SA  + L VLA+L P ++  P AG   DR   ++++ G  + R  +LL
Sbjct: 24  VALPLYVLDVTHSAKIMTLFVLADLIPSIITTPIAGVFGDRYDRKKIMVGFDLIR-GVLL 82

Query: 68  LLALPAARSSAAPLLAVAALTAVCNRFFSPAANALLPCLVCPGQLPAANACAMAARMAGM 127
            L +     +   LL V  + A+ N FFS    A+ P LV P +L  AN+  M+A +   
Sbjct: 83  FLVIAFNFLTIRCLLVVQVIMAIMNAFFSAGTGAMYPDLVKPEELERANSIVMSASIISR 142

Query: 128 ALGAMVGGVLAGVAGNDATILTMGLLMLGCGGLSLSLPERRRLAATQSPAWRWTLVVQCV 187
            +G  +GG + G  G    IL   +   G G   + +    +    +  +     + + +
Sbjct: 143 LVGPAIGGFVYGFGGIKLAILMNAISFFGSGLFEIFIKYEWKTRNIEGFSDFVRDIKEGL 202

Query: 188 AAPGRSGWLAIAAGMLVM-AALGSIEILAIVY---VKQVLHRPAADVGLLFGAYGAGVVL 243
                + +++   G++++  ALG+    +I+Y   ++++L   +   GL+  A+  G ++
Sbjct: 203 KFIMSNSFISTLIGLVILLNALGA-PFASIIYPYAMREILKFSSQQFGLVESAFMLGALI 261

Query: 244 GLVLSSWHRIVARSDDVIRLSLL---LMCVAIGLVSQVERL--GSAALLVSMAGLAEGM- 297
           G ++            + RL L+   +  + I ++S    L   SA +L+ + G   GM 
Sbjct: 262 GNLIVGAFLGAKAGRYIFRLFLVNGAVELIFILIISPFLALPRNSAFMLLLVLGATMGMA 321

Query: 298 --VMSLGLLRLYQTVDPSRL-GRATALLDSASGAAFLLAVVVTGLLADTVAA 346
             ++++ L    Q   PS + GR  + ++  +  A  L++VV G L DT+ A
Sbjct: 322 GAMINVPLASKLQRAVPSEIRGRVFSTMEMLARIANPLSLVVVGPLVDTIGA 373


>TM1336 [GEPR] COG0477 Permeases of the major facilitator superfamily Tma
           Thermotoga maritima
          Length = 390

 Score = 61.2 bits (147), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 47/171 (27%), Positives = 82/171 (47%), Gaps = 5/171 (2%)

Query: 14  MFELTQSAFQVMLLVLAELAPMLLLGPWAGAVTDRSGLRRVLGGSCVARLALLLLLALPA 73
           ++  T S+  V L +++   P +++ P+AG V DR   R ++    + R  L + L L  
Sbjct: 30  LYSKTGSSEYVGLFMISSFLPAIIVSPFAGTVVDRHSRRNMMVVMDILRGVLFMYLFLME 89

Query: 74  ARS--SAAPLLAVAALTAVCNRFFSPAANALLPCLVCPGQLPAANACAMAARMAGMALGA 131
             S  + A LL V  L +V + FF+PA ++LLP LV    L  AN+     +     LG 
Sbjct: 90  YFSELTMALLLIVTVLVSVFDSFFNPAVDSLLPDLVRKENLVRANSLYRLLKNLSKILGP 149

Query: 132 MVGGVLAGVAGNDATIL--TMGLLMLGCGGLSLSLPERR-RLAATQSPAWR 179
            +G +L  V G    IL  ++  L+ G   + + + E+  +  + +   W+
Sbjct: 150 ALGSLLLKVVGLAGVILINSLSFLISGIFEMFIKVEEKHLKKVSKERNMWQ 200


>mlr4214 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo
           Mesorhizobium loti
          Length = 412

 Score = 60.1 bits (144), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 51/165 (30%), Positives = 78/165 (47%), Gaps = 3/165 (1%)

Query: 14  MFELTQSAFQVMLLVLAELAPMLLLGPWAGAVTDRSGLRRVLGGSCVARLALLLLLALPA 73
           M++LT+  F + ++ + +  P LLL    GAV DR G R ++  + V      L L    
Sbjct: 45  MYDLTRDPFDLGIVGIVQFLPSLLLVLVTGAVADRFGRRLIMALAVVVEAICALALLALT 104

Query: 74  ARSSAAPL--LAVAALTAVCNRFFSPAANALLPCLVCPGQLPAANACAMAARMAGMALGA 131
            RS + PL    V A+  V   FF PA+ +L   LV P     A A   +A      +G 
Sbjct: 105 LRSISGPLPIFCVLAMFGVARAFFGPASASLFANLVPPEDFANAIAWNSSAWQTATIVGP 164

Query: 132 MVGGVLAGVAGNDATILTMGLLMLGCGGLSLSLPERRRLAATQSP 176
           + GG+L GV+  +    T  +LML  G L  ++P+  +   T+ P
Sbjct: 165 VAGGLLYGVS-PEVAYGTAAVLMLASGLLIFTIPKPAQRTETEKP 208