BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0217.p (626 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1071 [L] COG0322 Nuclease subunit of the excinuclease complex... 894 0.0 NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex... 622 e-178 NMB1326 [L] COG0322 Nuclease subunit of the excinuclease complex... 609 e-174 PA2585 [L] COG0322 Nuclease subunit of the excinuclease complex ... 564 e-160 XF2311 [L] COG0322 Nuclease subunit of the excinuclease complex ... 520 e-147 >RSc1071 [L] COG0322 Nuclease subunit of the excinuclease complex Rso Ralstonia solanacearum Length = 654 Score = 894 bits (2311), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/653 (69%), Positives = 516/653 (79%), Gaps = 38/653 (5%) Query: 5 PASPLPDPREAVLET---VARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLT 61 P +P DP EA + +ARLP LPGVYRYFDA+ +VLYVGKARDLKKRVSSYF KTL Sbjct: 9 PPAPAVDPSEAAFDAKAHIARLPSLPGVYRYFDAQGSVLYVGKARDLKKRVSSYFTKTLL 68 Query: 62 SPRIAMMVERIARLETTVTRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAF 121 SPRIAMMV +IA +ETTV RSEAEALLLENNLIK L PR+NILFRDDKSYPYLK+T HA+ Sbjct: 69 SPRIAMMVAKIAHIETTVVRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTQHAY 128 Query: 122 PRMAYYRGAVDKRNQYFGPFPNAGAVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIH 181 PRMAYYRGA D+++QYFGPFP+A AV+ES+QILQKVF LRTCEDTVF+NRTRPCLLHQIH Sbjct: 129 PRMAYYRGATDRKHQYFGPFPSAHAVRESMQILQKVFQLRTCEDTVFNNRTRPCLLHQIH 188 Query: 182 RCSGPCVNLVSREDYAIDVENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQI 241 RC+ PCV +S EDYA DV NA+ FL GRQ EVM+ L+ KM AA L+FEQAA VRDQI Sbjct: 189 RCTAPCVQAISAEDYARDVANAAGFLLGRQDEVMQTLQDKMQRHAAALEFEQAATVRDQI 248 Query: 242 GSLSSVLHQQSMETVSDA-DIDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAM 300 G+LS+VL +QS+E V A DIDI+AV ++GG ACVNLAMVRGGRHLGD+AYFPTHV++ Sbjct: 249 GALSTVLTRQSVEEVGQASDIDILAVAIKGGHACVNLAMVRGGRHLGDKAYFPTHVEEG- 307 Query: 301 DTAEDSIDVE-----------------------VLKAFLAQHYIDKFIPGSLIVGTEFDD 337 A +DVE +L+AF+AQHY+D+F+P L+V Sbjct: 308 -AAIVGVDVEADVPEGAETQPEPARDPERMARDILEAFVAQHYLDQFVPPVLVVSHPIRA 366 Query: 338 PALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALARLLSEQGSQQARTRALADV 397 L+ AL Q G R+++ QPQG RR WLEMA KGAE++LAR LSEQGSQQARTRALA+ Sbjct: 367 AGLIEALAAQAGRRVSVVRQPQGARRAWLEMAEKGAELSLARRLSEQGSQQARTRALAET 426 Query: 398 LELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGEYRRYNINDITPGDDYAAM 457 + ++ +DL LR ECFDISHT GEATQASCVVFH HAMQNGEYRRYNI DI PGDDYAAM Sbjct: 427 IGVDLEDLAALRVECFDISHTAGEATQASCVVFHSHAMQNGEYRRYNIQDIIPGDDYAAM 486 Query: 458 RQVLTRRYEKV----ANGEGVRPDIVLIDGGKGQVEMARQVLTELGLDISLIVGVAKGEG 513 RQVLTRRY+KV A P +VLIDGGKGQVE+ARQV ELGLDI L+VGVAKGEG Sbjct: 487 RQVLTRRYQKVVEQAAEDAPDMPRVVLIDGGKGQVEVARQVFEELGLDIGLLVGVAKGEG 546 Query: 514 RKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITGMRAKRSKASAPSVASAX 573 RKVGLETLVFADGR ELG+ SAALML+AQIRDEAHRFAITGMRAKR+KA S Sbjct: 547 RKVGLETLVFADGRPSLELGQGSAALMLVAQIRDEAHRFAITGMRAKRAKARNTS----- 601 Query: 574 RLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQLAEEIYRQLH 626 RLEEIEGIGAKRRQRLL RFGGLRGV ASV++LA+VEGIS+ LAEEIYRQLH Sbjct: 602 RLEEIEGIGAKRRQRLLARFGGLRGVMAASVEELATVEGISQTLAEEIYRQLH 654 >NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex NmA Neisseria meningitidis Z2491 Length = 628 Score = 622 bits (1604), Expect = e-178, Method: Compositional matrix adjust. Identities = 324/615 (52%), Positives = 417/615 (67%), Gaps = 22/615 (3%) Query: 20 VARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTV 79 + LP LPGVYR+FD VLYVGKA +LK+RVS YFQK SPRIA+MV+++ +ETT+ Sbjct: 28 LKNLPKLPGVYRFFDEGGKVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTI 87 Query: 80 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRNQYFG 139 TRSEAEAL+LENN IK L P++NILFRDDKSYPYL ++GH +P+MAYYRG + K NQYFG Sbjct: 88 TRSEAEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFG 147 Query: 140 PFPNAGAVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCVNLVSREDYAID 199 P+PN+ AV++SIQILQKVF+LRTCED+VF +R RPCLL+QI RC+ PCV +S EDY Sbjct: 148 PYPNSNAVRDSIQILQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDS 207 Query: 200 VENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETV--- 256 V A+ FL G+ E+ L+ KM AA+L+FE+AA RDQI +L + Q +++ Sbjct: 208 VRQAATFLNGKTDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPN 267 Query: 257 SDADIDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFL 316 + DID++A+ V G CV+ +RGGRH+GD+++FP +D +D + AF+ Sbjct: 268 NPNDIDLLALAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAE-----AFV 322 Query: 317 AQHYIDKFIPGSLIVGTEFDDPALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIA 376 AQHY+ K P +I D AL AL + G ++ + G+R+ WL+MA + A++A Sbjct: 323 AQHYLGKSKPDIIINNFPVPD-ALKEALEGEHGKQMQFVTKTIGERKVWLKMAEQNAQMA 381 Query: 377 LARLLSEQGSQQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQ 436 +A+ +Q +QQ R LA +L ++ D L+ R ECFDISHTQGEAT ASCVV+ +Q Sbjct: 382 IAQRRLQQSNQQHRIDELAKILGMDSDGLN--RLECFDISHTQGEATIASCVVYDEQNIQ 439 Query: 437 NGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGEGVR-PDIVLIDGGKGQVEMA 491 +YRRYNI PGDDYAAMR+VLTRRY K+ ANGE V+ PD VLIDGGKGQ+ +A Sbjct: 440 PSQYRRYNITTAKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGIA 499 Query: 492 RQVLTELGLDISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHR 551 V ELGL I L VG+AKG RK G+E L+ L S AL L+ +RDE+HR Sbjct: 500 VSVWEELGLHIPL-VGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHR 558 Query: 552 FAITGMRAKRSKASAPSVASAXRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVE 611 FAITG R KR KA S L +I G+G+KRRQ LL RFGGLRGV AS +DL VE Sbjct: 559 FAITGHRKKRDKARVTS-----SLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVE 613 Query: 612 GISRQLAEEIYRQLH 626 GIS+ LAE IY LH Sbjct: 614 GISKALAETIYEHLH 628 >NMB1326 [L] COG0322 Nuclease subunit of the excinuclease complex Nme Neisseria meningitidis MC58 Length = 617 Score = 609 bits (1570), Expect = e-174, Method: Compositional matrix adjust. Identities = 322/615 (52%), Positives = 418/615 (67%), Gaps = 22/615 (3%) Query: 20 VARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTV 79 + LP+LPGVYR+F+ NVLYVGKA +LK+RVS YFQK SPRIA+MV+++ +ETT+ Sbjct: 17 LKNLPNLPGVYRFFNESGNVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTI 76 Query: 80 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRNQYFG 139 TRSE+EAL+LENN IK L P++NILFRDDKSYPYL ++GH +P+MAYYRG + K NQYFG Sbjct: 77 TRSESEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFG 136 Query: 140 PFPNAGAVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCVNLVSREDYAID 199 P+PN+ AV++SIQ+LQKVF+LRTCED+VF +R RPCLL+QI RC+ PCV +S EDY Sbjct: 137 PYPNSNAVRDSIQVLQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDS 196 Query: 200 VENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETV--- 256 V A+ FL G+ E+ L+ KM AA+L+FE+AA RDQI +L + Q +++ Sbjct: 197 VREAATFLNGKTDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPN 256 Query: 257 SDADIDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFL 316 + DID++A+ V G CV+ +RGGRH+GD+++FP +D +D + AF+ Sbjct: 257 NPNDIDLLALAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAE-----AFV 311 Query: 317 AQHYIDKFIPGSLIVGTEFDDPALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIA 376 AQHY+ K P +I D AL AL + G ++ + G+R+ L+MA + A++A Sbjct: 312 AQHYLGKSKPDIIISNFPVPD-ALKEALEGEHGKQMQFVTKTIGERKVRLKMAEQNAQMA 370 Query: 377 LARLLSEQGSQQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQ 436 +A+ +Q SQQ R LA +L ++ D L+ R ECFDISHTQGEAT ASCVV+ +Q Sbjct: 371 IAQRRLQQSSQQHRIDELAKILGMDSDGLN--RLECFDISHTQGEATIASCVVYDEQNIQ 428 Query: 437 NGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGEGVR-PDIVLIDGGKGQVEMA 491 +YRRYNI PGDDYAAMR+VLTRRY K+ ANGE V+ PD VLIDGGKGQ+ +A Sbjct: 429 PSQYRRYNITTAKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGVA 488 Query: 492 RQVLTELGLDISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHR 551 V ELGL I L VG+AKG RK G+E L+ L S AL L+ +RDE+HR Sbjct: 489 VSVWEELGLHIPL-VGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHR 547 Query: 552 FAITGMRAKRSKASAPSVASAXRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVE 611 FAITG R KR KA S L +I G+G+KRRQ LL RFGGLRGV AS +DL VE Sbjct: 548 FAITGHRKKRDKARVTS-----SLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVE 602 Query: 612 GISRQLAEEIYRQLH 626 GIS+ LAE IY LH Sbjct: 603 GISKALAETIYNHLH 617 >PA2585 [L] COG0322 Nuclease subunit of the excinuclease complex Pae Pseudomonas aeruginosa Length = 608 Score = 564 bits (1454), Expect = e-160, Method: Compositional matrix adjust. Identities = 301/605 (49%), Positives = 404/605 (66%), Gaps = 21/605 (3%) Query: 27 PGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVTRSEAEA 86 PGVYR FDAE +LYVGKA+ LKKR++SYF+K+ +P+ A +V RIA++ETT+T +E EA Sbjct: 18 PGVYRMFDAEAKLLYVGKAKSLKKRLASYFRKSGLAPKTAALVARIAQVETTITANETEA 77 Query: 87 LLLENNLIKTLRPRFNILFRDDKSYPYLKITGH-AFPRMAYYRGAVDKRNQYFGPFPNAG 145 LLLE LIK RP +NIL RDDKSYP++ ++ +PR++ +RGA ++ +YFGP+P+AG Sbjct: 78 LLLEQTLIKEWRPPYNILLRDDKSYPFVFLSSEDEYPRLSLHRGAKKRKGRYFGPYPSAG 137 Query: 146 AVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCVNLVSREDYAIDVENASK 205 A++ES+ +LQK FL+R CED+ F NRTRPCL +QI RC GPCV LVS E+YA DV ++ Sbjct: 138 AIRESLNLLQKAFLVRQCEDSYFRNRTRPCLQYQIKRCKGPCVGLVSPEEYAEDVRHSVM 197 Query: 206 FLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDADIDIIA 265 FL GR + + + L M A L FE+AA +RDQ+ L V QQSME + D+DI+A Sbjct: 198 FLEGRSNALADELNVGMEQAAMRLDFEKAAELRDQVAILRRVQDQQSMEG-GNGDVDIVA 256 Query: 266 VVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFLAQHYI---D 322 +V G ACV+L VRGGR LG + +FP E+ + EVL AFL Q+Y+ + Sbjct: 257 AIVTPGGACVHLISVRGGRVLGSKNFFP------QVAIEEEVG-EVLLAFLGQYYLSHQE 309 Query: 323 KFIPGSLIVGTEFDD-PALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALARLL 381 + +P LIV +D P L+ A+ E G + ++++ +G R +W ++A AE AL L Sbjct: 310 RDLPAELIVNVTHEDFPVLVSAIAEARGRELEISYRVRGTRARWQQLAVTNAEQALGARL 369 Query: 382 SEQGSQQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGEYR 441 + + AR ALA+ L+L R ECFDISH+ GEAT ASCVVF +YR Sbjct: 370 ANRQHVAARFEALAEALDLAEPPQ---RLECFDISHSSGEATVASCVVFGPEGPLKSDYR 426 Query: 442 RYNINDITPGDDYAAMRQVLTRRYEKVANGEGVRPDIVLIDGGKGQVEMARQVLTELGLD 501 RYNI +T GDDYAAM Q LTRR+ ++ +GEG PDI+L+DGGKGQ+ MA++VL EL + Sbjct: 427 RYNIEGVTAGDDYAAMHQALTRRFSRLKDGEGKMPDILLVDGGKGQLAMAQEVLQELAVA 486 Query: 502 ISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITGMRAKR 561 +++GVAKG RK GLETL D L +S AL LI QIRDEAHRFAITG RA+R Sbjct: 487 GLILLGVAKGVTRKPGLETLYLNDASHEFTLPADSPALHLIQQIRDEAHRFAITGHRARR 546 Query: 562 SKASAPSVASAXRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQLAEEI 621 KA S LE++ G+G KRR+ LL FGGL+ ++ AS+D+LA GIS++LAE+I Sbjct: 547 GKARRTST-----LEDVPGVGPKRRRDLLKHFGGLQELSRASIDELAKAPGISKKLAEQI 601 Query: 622 YRQLH 626 Y LH Sbjct: 602 YAVLH 606 >XF2311 [L] COG0322 Nuclease subunit of the excinuclease complex Xfa Xylella fastidiosa 9a5c Length = 627 Score = 520 bits (1338), Expect = e-147, Method: Compositional matrix adjust. Identities = 279/611 (45%), Positives = 390/611 (63%), Gaps = 24/611 (3%) Query: 21 ARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVT 80 A L PGVY + A+D +LYVGKA L+KRV+SYF T + R+ M+ ++ R++ T+T Sbjct: 22 AHLSMAPGVYCMYAADDTLLYVGKAGALRKRVASYFNGTPKNTRLTAMLAQVVRMDVTIT 81 Query: 81 RSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRNQYFGP 140 R+EAEALLLEN LIK+L PR+N+L RDDKSYPY+ +T A+PR+A +RG +YFGP Sbjct: 82 RNEAEALLLENQLIKSLAPRYNVLLRDDKSYPYVLLTREAWPRIALHRGPQIVPGRYFGP 141 Query: 141 FPNAGAVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCVNLVSREDYAIDV 200 +P AV++ + ++ K+F LR+CED+VF NR+RPCL +QI RCS PCVN+V+ ++Y V Sbjct: 142 YPGVTAVRDMLNLIHKLFKLRSCEDSVFRNRSRPCLQYQIGRCSAPCVNVVTHDNYTEAV 201 Query: 201 ENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDAD 260 + FL G+ + E L Q M + L+FEQAA +RD + SL S+ ++Q ++ + AD Sbjct: 202 RRVTLFLEGKSDLLAEELIQAMQVASEHLEFEQAARLRDLLTSLRSMQNRQYVDGRA-AD 260 Query: 261 IDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFLAQHY 320 +D++A G ACV L R GR+LG R +FP T + E+L AF++Q+Y Sbjct: 261 LDVLACAALSGHACVLLLSFRDGRNLGTRMFFP-------KTNGEERTAEILSAFVSQYY 313 Query: 321 IDKFIPGSLIVGTEFDDPALM-MALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALAR 379 + P +++ E D L+ A H+I+L + +G+R ++E+A + A++AL+ Sbjct: 314 AEYPPPPEILLDQEIPDHTLLEAAFSRSSAHKISLRWNVRGERAGYVELAVRNAQVALST 373 Query: 380 LLSEQGSQQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGE 439 L+ Q +Q+ R+ A+ +L LE R ECFDISHT GEAT ASCVVF + Sbjct: 374 ELTSQRAQRVRSEAVRQLLGLEEPI---KRVECFDISHTMGEATVASCVVFDAVGPVRSQ 430 Query: 440 YRRYNINDITPGDDYAAMRQVLTRRYEKVA--NGEGVRPDIVLIDGGKGQVEMARQVLTE 497 YRRYNI ITPGDDYAAMRQ + RR+ + + +G RPD++ IDGG GQ+ A+ L Sbjct: 431 YRRYNITGITPGDDYAAMRQAIERRFRRAVEEDKQGERPDVLFIDGGAGQLAQAKMALNA 490 Query: 498 LGLDISLIVGVAKGEGRKVGLETLVFADGRAPKEL--GKESAALMLIAQIRDEAHRFAIT 555 +G++ L+VGV+KGE R+ G ETL+ DG +EL G S AL I Q+RDEAHRFAIT Sbjct: 491 VGVESVLLVGVSKGEERRAGHETLIMLDG---QELHPGAASPALQFIQQVRDEAHRFAIT 547 Query: 556 GMRAKRSKASAPSVASAXRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISR 615 G RA+R K S +LE+I GIG++RR LL FGGL GV A ++A VEGIS Sbjct: 548 GHRARRQKTRMTS-----KLEDIPGIGSRRRANLLKHFGGLAGVKAAGQTEIARVEGIST 602 Query: 616 QLAEEIYRQLH 626 LA +IY LH Sbjct: 603 ALAAKIYASLH 613