BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0181.p (433 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2337 [J] COG0172 Seryl-tRNA synthetase Rso Ralstonia solanace... 686 0.0 NMB1684 [J] COG0172 Seryl-tRNA synthetase Nme Neisseria meningit... 617 e-176 NMA1943 [J] COG0172 Seryl-tRNA synthetase NmA Neisseria meningit... 611 e-174 PA2612 [J] COG0172 Seryl-tRNA synthetase Pae Pseudomonas aeruginosa 566 e-161 STM0963 [J] COG0172 Seryl-tRNA synthetase Sty Salmonella typhimu... 546 e-155 >RSc2337 [J] COG0172 Seryl-tRNA synthetase Rso Ralstonia solanacearum Length = 438 Score = 686 bits (1771), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/438 (76%), Positives = 368/438 (84%), Gaps = 5/438 (1%) Query: 1 MIDIQLLRKDIENVAARLAARKFVLDVAGFNALEAERKQIQTRTEELQGKRNSLSKQIGM 60 M+DIQLLRKDI+ VAARL R + LDVAGF ALEAERK IQTRTEELQ +RNSLSKQIGM Sbjct: 1 MLDIQLLRKDIDAVAARLNDRGYELDVAGFAALEAERKAIQTRTEELQARRNSLSKQIGM 60 Query: 61 LKGKGEDASAVMAEVNGIGDELKASATRLEEVQQQMNLFLQAVPNLPHESVPVGNDESGN 120 LKGKGEDASAVMAEV GIGDELKASA +L+ VQ ++ L ++PN+PHESVP G E+ N Sbjct: 61 LKGKGEDASAVMAEVAGIGDELKASAAQLDVVQGRLQDLLLSIPNVPHESVPAGKSEAEN 120 Query: 121 VELRKVGTPRQFDFEIKDHVDVGAALGLDFDTATKLTGSRFAVLKGGIARLHRALAQFML 180 VE+R+ GTPR FDF +KDHVD+GA LGLDFD A KL+GSRFAVLKG +ARLHRALAQFML Sbjct: 121 VEVRREGTPRAFDFPVKDHVDLGAGLGLDFDVAAKLSGSRFAVLKGPVARLHRALAQFML 180 Query: 181 NTHTMEHGYTECYTPYIVNADSLRGTGQLPKFEADLF-AAKKGGQEGEAENAA----LYL 235 +THT EHGYTE Y PYIVNA S+RGTGQLPKFE DLF +K GQ EAE YL Sbjct: 181 DTHTQEHGYTEAYVPYIVNAASMRGTGQLPKFEEDLFRVPRKMGQATEAEAGEHVENFYL 240 Query: 236 IPTAEVPLTNFVRDEIVAGDALPMKFTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQ 295 IPTAEVPLTN VRDEIVAGDALPMKF AHSPCFRSEAGSYG+DTRGMIRQHQFDKVEMVQ Sbjct: 241 IPTAEVPLTNLVRDEIVAGDALPMKFAAHSPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQ 300 Query: 296 IVHPEQSYDALDEMLGHAETILKKLGLPYRVITLCTGDMGFGAAKTYDIEVWLPAQNTYR 355 IV PE S++ALD M HAE IL+KL LP+R + LCTGDMGFG+ KTYDIEVW+PAQNTYR Sbjct: 301 IVQPETSFEALDAMTHHAENILRKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYR 360 Query: 356 EISSVSNCEAFQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAVLENYQQADGSVDI 415 EISS SN FQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAVLENYQ ADGSV + Sbjct: 361 EISSCSNMGDFQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAVLENYQNADGSVTV 420 Query: 416 PEALQPYMGGVTRLVPGA 433 P AL+PY+GG L P A Sbjct: 421 PAALRPYLGGQAVLKPAA 438 >NMB1684 [J] COG0172 Seryl-tRNA synthetase Nme Neisseria meningitidis MC58 Length = 431 Score = 617 bits (1591), Expect = e-176, Method: Compositional matrix adjust. Identities = 292/431 (67%), Positives = 350/431 (81%), Gaps = 5/431 (1%) Query: 1 MIDIQLLRKDIENVAARLAARKFVLDVAGFNALEAERKQIQTRTEELQGKRNSLSKQIGM 60 M+DIQLLR + VA RLA R + D A F+ LE RK +Q +TEELQ RNS+SKQIG Sbjct: 1 MLDIQLLRSNTAAVAERLARRGYDFDTARFDTLEERRKSVQVKTEELQASRNSISKQIGA 60 Query: 61 LKGKG--EDASAVMAEVNGIGDELKASATRLEEVQQQMNLFLQAVPNLPHESVPVGNDES 118 LKG+G E+A A M +V I +L+ +A L+ VQ++++ +L ++PNLPHESVP G DE+ Sbjct: 61 LKGQGKHEEAQAAMNQVAQIKTDLEQAAADLDAVQKELDAWLLSIPNLPHESVPAGKDET 120 Query: 119 GNVELRKVGTPRQFDFEIKDHVDVGAALGLDFDTATKLTGSRFAVLKGGIARLHRALAQF 178 NVE+RKVGTPR+FDFEIKDHVD+G LGLDF+ KL+G+RF V++G IARLHRALAQF Sbjct: 121 ENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSGARFTVMRGQIARLHRALAQF 180 Query: 179 MLNTHTMEHGYTECYTPYIVNADSLRGTGQLPKFEADLFAAKKGGQEGEAENAALYLIPT 238 ML+THT++HGYTE YTPYIV+ +L+GTGQLPKF DLF +GG E + YLIPT Sbjct: 181 MLDTHTLQHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDETKTTQ---YLIPT 237 Query: 239 AEVPLTNFVRDEIVAGDALPMKFTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVH 298 AEV LTN V D I+ + LP+K TAHSPCFRSEAGSYG+DTRG+IRQHQFDKVEMVQIVH Sbjct: 238 AEVTLTNTVADSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVH 297 Query: 299 PEQSYDALDEMLGHAETILKKLGLPYRVITLCTGDMGFGAAKTYDIEVWLPAQNTYREIS 358 PE+SY+ L+EM+GHAE ILK L LPYRVITLCTGDMGFGAAKTYD+EVW+PAQNTYREIS Sbjct: 298 PEKSYETLEEMVGHAENILKALELPYRVITLCTGDMGFGAAKTYDLEVWVPAQNTYREIS 357 Query: 359 SVSNCEAFQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAVLENYQQADGSVDIPEA 418 S SNCE FQARR++ARF++ GK L+HTLNGSGLAVGRTLVAVLEN+Q ADGS++IP A Sbjct: 358 SCSNCEDFQARRLKARFKDENGKNRLVHTLNGSGLAVGRTLVAVLENHQNADGSINIPAA 417 Query: 419 LQPYMGGVTRL 429 LQPYMGGV +L Sbjct: 418 LQPYMGGVAKL 428 >NMA1943 [J] COG0172 Seryl-tRNA synthetase NmA Neisseria meningitidis Z2491 Length = 431 Score = 611 bits (1575), Expect = e-174, Method: Compositional matrix adjust. Identities = 290/431 (67%), Positives = 347/431 (80%), Gaps = 5/431 (1%) Query: 1 MIDIQLLRKDIENVAARLAARKFVLDVAGFNALEAERKQIQTRTEELQGKRNSLSKQIGM 60 M+DIQLLR + VA RLA R + D A F+ALE RK +Q +TEELQ RNS+SKQIG Sbjct: 1 MLDIQLLRSNTAAVAERLARRGYDFDTARFDALEERRKSVQVKTEELQASRNSISKQIGA 60 Query: 61 LKGKG--EDASAVMAEVNGIGDELKASATRLEEVQQQMNLFLQAVPNLPHESVPVGNDES 118 LKG+G E+A M +V I +L+ +A L+ VQ++++ +L ++PNLPHE VP G DE+ Sbjct: 61 LKGQGKHEEAQVAMDQVAQIKTDLEQAAADLDAVQKELDAWLLSIPNLPHEDVPFGKDET 120 Query: 119 GNVELRKVGTPRQFDFEIKDHVDVGAALGLDFDTATKLTGSRFAVLKGGIARLHRALAQF 178 NVE+RKVGTPR+FDFEIKDHVD+G LGLDF+ KL+G+RF V++G IARLHRALAQF Sbjct: 121 ENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSGARFTVMRGQIARLHRALAQF 180 Query: 179 MLNTHTMEHGYTECYTPYIVNADSLRGTGQLPKFEADLFAAKKGGQEGEAENAALYLIPT 238 ML+THT++HGYTE YTPYIV+ +L+GTGQLPKF DLF +GG E + YLIPT Sbjct: 181 MLDTHTLKHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDESKTTQ---YLIPT 237 Query: 239 AEVPLTNFVRDEIVAGDALPMKFTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVH 298 AEV LTN V I+ + LP+K TAHSPCFRSEAGSYG+DTRG+IRQHQFDKVEMVQIVH Sbjct: 238 AEVTLTNTVAGSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVH 297 Query: 299 PEQSYDALDEMLGHAETILKKLGLPYRVITLCTGDMGFGAAKTYDIEVWLPAQNTYREIS 358 PE+SY+ L+EM+GHAE ILK L LPYRVITLCTGDMGFGA KTYD+EVW+PAQNTYREIS Sbjct: 298 PEKSYETLEEMVGHAENILKALELPYRVITLCTGDMGFGATKTYDLEVWVPAQNTYREIS 357 Query: 359 SVSNCEAFQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAVLENYQQADGSVDIPEA 418 S SNCE FQARRM+ARF++ GK L+HTLNGSGLAVGRTLVAVLEN+Q ADGS++IP A Sbjct: 358 SCSNCEDFQARRMKARFKDENGKNRLVHTLNGSGLAVGRTLVAVLENHQNADGSINIPAA 417 Query: 419 LQPYMGGVTRL 429 LQPYMGGV +L Sbjct: 418 LQPYMGGVAKL 428 >PA2612 [J] COG0172 Seryl-tRNA synthetase Pae Pseudomonas aeruginosa Length = 426 Score = 566 bits (1459), Expect = e-161, Method: Compositional matrix adjust. Identities = 274/428 (64%), Positives = 339/428 (79%), Gaps = 8/428 (1%) Query: 1 MIDIQLLRKDIENVAARLAARKFVLDVAGFNALEAERKQIQTRTEELQGKRNSLSKQIGM 60 M+D +L+R + VAARLA R F LDVA ALE +RK +QTRTE+LQ +RN+ SK IG Sbjct: 1 MLDPKLVRTQPQEVAARLATRGFQLDVARIEALEEQRKSVQTRTEQLQAERNARSKAIGQ 60 Query: 61 LKGKGEDASAVMAEVNGIGDELKASATRLEEVQQQMNLFLQAVPNLPHESVPVGNDESGN 120 K +GED + ++A+V+ +G EL+ +L+ +Q +++ L +PNLPHESVPVG DE N Sbjct: 61 AKQRGEDIAPLLADVDRMGSELEEGKRQLDAIQGELDAMLLGIPNLPHESVPVGADEDAN 120 Query: 121 VELRKVGTPRQFDFEIKDHVDVGAALG-LDFDTATKLTGSRFAVLKGGIARLHRALAQFM 179 VE+R+ GTP+ FDFE+KDHV +G G LDF+TA KL+G+RFA+++G IARLHRALAQFM Sbjct: 121 VEVRRWGTPKTFDFEVKDHVALGERHGWLDFETAAKLSGARFALMRGPIARLHRALAQFM 180 Query: 180 LNTHTMEHGYTECYTPYIVNADSLRGTGQLPKFEADLFAAKKGGQEGEAENAALYLIPTA 239 +N HT EHGY E YTPY+V A +L+GTGQLPKFE DLF K G++GEA+ LYLIPTA Sbjct: 181 INLHTAEHGYEEAYTPYLVQAPALQGTGQLPKFEEDLF---KIGRDGEAD---LYLIPTA 234 Query: 240 EVPLTNFVRDEIVAGDALPMKFTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVHP 299 EV LTN V +I+ LP+KF AH+PCFRSEAG+ GRDTRGMIRQHQFDKVEMVQIV P Sbjct: 235 EVSLTNIVSGQILDAKQLPLKFVAHTPCFRSEAGASGRDTRGMIRQHQFDKVEMVQIVDP 294 Query: 300 EQSYDALDEMLGHAETILKKLGLPYRVITLCTGDMGFGAAKTYDIEVWLPAQNTYREISS 359 SY+AL+ + +AE +L+ L LPYRV+ LCTGDMGFGA KTYD+EVW+P+Q+ YREISS Sbjct: 295 ATSYEALEGLTANAERVLQLLELPYRVLALCTGDMGFGATKTYDLEVWVPSQDKYREISS 354 Query: 360 VSNCEAFQARRMQARFRNAQ-GKPELLHTLNGSGLAVGRTLVAVLENYQQADGSVDIPEA 418 SNC FQARRMQAR+RN + GKPEL+HTLNGSGLAVGRTLVAVLENYQQADGS+ +PE Sbjct: 355 CSNCGDFQARRMQARYRNPETGKPELVHTLNGSGLAVGRTLVAVLENYQQADGSIRVPEV 414 Query: 419 LQPYMGGV 426 L+PYM G+ Sbjct: 415 LKPYMAGI 422 >STM0963 [J] COG0172 Seryl-tRNA synthetase Sty Salmonella typhimurium LT2 Length = 430 Score = 546 bits (1407), Expect = e-155, Method: Compositional matrix adjust. Identities = 268/428 (62%), Positives = 321/428 (75%), Gaps = 4/428 (0%) Query: 1 MIDIQLLRKDIENVAARLAARKFVLDVAGFNALEAERKQIQTRTEELQGKRNSLSKQIGM 60 M+D LLR + + VA +LA R F LDV ALE RK +Q TE LQ +RNS SK IG Sbjct: 1 MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVNTENLQAERNSRSKSIGQ 60 Query: 61 LKGKGEDASAVMAEVNGIGDELKASATRLEEVQQQMNLFLQAVPNLPHESVPVGNDESGN 120 K +GED + EVN +G+EL A+ L+ + ++ +PNLP + VPVG DE+ N Sbjct: 61 AKARGEDIEPLRLEVNKLGEELDAAKAELDTLLAEIRDIALTIPNLPADEVPVGKDENDN 120 Query: 121 VELRKVGTPRQFDFEIKDHVDVGAA-LGLDFDTATKLTGSRFAVLKGGIARLHRALAQFM 179 VE+ + GTPR+FDFEI+DHV +G GLDF A KLTGSRF V+KG IAR+HRAL+QFM Sbjct: 121 VEVSRWGTPREFDFEIRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFM 180 Query: 180 LNTHTMEHGYTECYTPYIVNADSLRGTGQLPKFEADLFAAKKGGQEGEAENAALYLIPTA 239 L+ HT +HGY+E Y PY+VN D+L GTGQLPKF DLF + +E ++ N AL IPTA Sbjct: 181 LDLHTEQHGYSENYVPYLVNHDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYAL--IPTA 238 Query: 240 EVPLTNFVRDEIVAGDALPMKFTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVHP 299 EVPLTN VRDEI+ D LP+K TAH+PCFRSEAGSYGRDTRG+IR HQFDKVEMVQIV P Sbjct: 239 EVPLTNLVRDEIIDEDQLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRP 298 Query: 300 EQSYDALDEMLGHAETILKKLGLPYRVITLCTGDMGFGAAKTYDIEVWLPAQNTYREISS 359 E S AL+EM GHAE +L+ LGLPYR I LCTGDMGFGA KTYD+EVW+PAQNTYREISS Sbjct: 299 EDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWVPAQNTYREISS 358 Query: 360 VSNCEAFQARRMQARFRN-AQGKPELLHTLNGSGLAVGRTLVAVLENYQQADGSVDIPEA 418 SN FQARRMQAR R+ + K L+HTLNGSGLAVGRTLVAV+ENYQQADG +++PE Sbjct: 359 CSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEV 418 Query: 419 LQPYMGGV 426 L+PYM G+ Sbjct: 419 LRPYMNGL 426